NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury
Hecker, Louise, Vittal, Ragini, Jones, Tamara, Jagirdar, Rajesh, Luckhardt, Tracy R, Horowitz, Jeffrey C, Pennathur, Subramaniam, Martinez, Fernando J +1 more·2009·Nature Medicine
DOI 10.1038/nm.2005
Cited by (857)
Items 501–600 of 857
- The molecular mechanisms of extracellular matrix-derived hydrogel therapy in idiopathic pulmonary fibrosis modelsDaniele Evangelista-Leite, Ana Cláudia Oliveira Carreira, Milton Yutaka Nishiyama, Sarah E. Gilpin, María Angélica Miglino · 2023 · Biomaterials
- α7‑nAchR agonist GTS‑21 reduces radiation‑induced lung injuryZijie Mei, Xiaoli Tian, Jing Chen, Yacheng Wang, Ye Yao, Xin Li, Chunxu Yang, Shimin Zhang, Conghua Xie · 2018 · Oncology Reports
- Role of various imbalances centered on alveolar epithelial cell/fibroblast apoptosis imbalance in the pathogenesis of idiopathic pulmonary fibrosisQing Wang, Zhaoliang Xie, Qi Wu, Zhixian Jin, Chao Yang, Jing Feng · 2021 · Chinese Medical Journal
- 1H NMR-based metabonomics study on serum of renal interstitial fibrosis rats induced by unilateral ureteral obstructionHaiyan Zhang, Jianmin Jia, Jinguo Cheng, Faqing Ye, Xiaokun Li, Hongchang Gao · 2011 · Molecular BioSystems
- The inhibitory effect of salvianolic acid B on TGF-β1-induced proliferation and differentiation in lung fibroblastsMin Zhang, Shuren Cao, Rui Zhang, Jin-Lan Jin, Youfeng Zhu · 2014 · Experimental Lung Research
- NADPH Oxidases and Their Roles in Skin Homeostasis and CarcinogenesisJana Rudolf, Houssam Raad, Alain Taı̈eb, Hamid Reza Rezvani · 2017 · Antioxidants and Redox Signaling
- S-Allylmercaptocysteine attenuates Bleomycin-induced pulmonary fibrosis in mice via suppressing TGF-β1/Smad and oxidative stress pathwaysChunyan Li, Xiao Sun, Ang Li, Min Mo, Zhongxi Zhao · 2019 · International Immunopharmacology
- Differential knockdown of TGF-β ligands in a three-dimensional co-culture tumor- stromal interaction model of lung cancerMasafumi Horie, Akira Saito, Satoshi F. Noguchi, Yoko Yamaguchi, Mitsuhiro Ohshima, Yasuyuki Morishita, Hiroshi I. Suzuki, Tadashi Kohyama, Takahide Nagase · 2014 · BMC Cancer
- AMPK signaling inhibits the differentiation of myofibroblasts: impact on age-related tissue fibrosis and degenerationAntero Salminen · 2023 · Biogerontology
- Emerging drugs for idiopathic pulmonary fibrosisMoisés Selman, Annie Pardo, Luca Richeldi, Stefania Cerri · 2011 · Expert Opinion on Emerging Drugs
- The evolving pharmacotherapy of pulmonary fibrosisHarpreet Lota, Athol Umfrey Wells · 2012 · Expert Opinion on Pharmacotherapy
- The use of exhaled air analysis in discriminating interstitial lung diseases: a pilot studyLaurent Plantier, Agnieszka Smolinska, Rianne Fijten, Martin Flamant, Jan W. Dallinga, Jean-Jacques Mercadier, Danielle M. F. A. Pachen, Marie‐Pia d’Ortho, Frederik‐Jan van Schooten, Bruno Crestani et al. · 2022 · Respiratory Research
- Transforming growth factor-β mediates endothelial dysfunction in rats during high salt intakeWenguang Feng, Wei‐Zhong Ying, Kristal J. Aaron, Paul W. Sanders · 2015 · American Journal of Physiology-Renal Physiology
- Possible Modulatory Effect of Tamarind Seed Coat Extract on Fluoride-Induced Pulmonary Inflammation and Fibrosis in RatsJaishabanu Ameeramja, Ekambaram Perumal · 2018 · Inflammation
- Current Advances in Idiopathic Pulmonary Fibrosis: The pathogenesis, Therapeutic Strategies and Candidate MoleculesMeng Lv, Yan Liu, Shuli Ma, Zutao Yu · 2019 · Future Medicinal Chemistry
- Thromboxane–Prostanoid Receptor Signaling Drives Persistent Fibroblast Activation in Pulmonary FibrosisSuzuki, Toshio, Kropski, Jonathan A., Chen, Jingyuan, Carrier, Erica J., Chen, Xinping, Sherrill, Taylor P., Winters, Nichelle I., Camarata, Jane E., Polosukhin, Vasiliy V., Han, Wei et al. · 2022 · American Journal of Respiratory and Critical Care Medicine
- Endothelial Reprogramming in AtherosclerosisLu Zhang, Wu Xin, Liang Hong · 2024 · Bioengineering
- Protocatechuic acid methyl ester modulates fluoride induced pulmonary toxicity in ratsJaishabanu Ameeramja, Vishnu Vignesh Kanagaraj, Ekambaram Perumal · 2018 · Food and Chemical Toxicology
- Galectin-3 Promotes ROS, Inflammation, and Vascular Fibrosis in Pulmonary Arterial HypertensionScott A. Barman, Zsuzsanna Bordán, Robert Karoly Batori, Stephen B. Haigh, David J. Fulton · 2021 · Advances in experimental medicine and biology
- Natural Bioactive Compounds Targeting NADPH Oxidase Pathway in Cardiovascular DiseasesSiti Sarah M. Sofiullah, Dharmani Devi Murugan, Suhaila Abd Muid, Yuan Seng Wu, Sharifah Zamiah Syed Abdul Kadir, Razif Abas, Nurul Raudzah Adib Ridzuan, Nor Hisam Zamakshshari, Ker Woon Choy · 2023 · Molecules
- Particulate Air Pollutants and Respiratory DiseasesAn‐Soo Jang · 2012 · InTech eBooks
- Centrality of bone marrow in the severity of gadolinium‐based contrast‐induced systemic fibrosisViktor R. Drel, Chunyan Tan, Jeffrey L. Barnes, Yves C. Gorin, Doug-Yoon Lee, Brent Wagner · 2016 · The FASEB Journal
- Role of Reactive Oxygen Species in Transforming Growth Factor Beta1-Induced Alpha Smooth-Muscle Actin and Collagen Production in Nasal Polyp-Derived FibroblastsIl‐Ho Park, Se-Jin Park, Jung-Sun Cho, You‐Mi Moon, Tae Hoon Kim, Sang Hag Lee, Heung-Man Lee · 2012 · International Archives of Allergy and Immunology
- Extracellular
<scp>HSP90α</scp>
promotes cellular senescence by modulating
<scp>TGF</scp>
‐β signaling in pulmonary fibrosisZhong, Wenshan, Chen, Weimou, Liu, Yuanyuan, Zhang, Jinming, Lu, Ye, Wan, Xuan, Qiao, Yujie, Huang, Haohua, Zeng, Zhaojin, Li, Wei et al. · 2022 · The FASEB Journal
- Abrogation of transforming growth factor-β-induced tissue fibrosis in mice with a global genetic deletion of Nox4Peter J. Wermuth, Fabian A. Mendoza, Sergio A. Jiménez · 2018 · Laboratory Investigation
- Wound Healing Promoting Activity of Tonsil-Derived Stem Cells on 5-Fluorouracil-Induced Oral Mucositis ModelHarry Jung, Han Su Kim, Jun Ho Lee, Jae Jun Lee, Hae Sang Park · 2019 · Tissue Engineering and Regenerative Medicine
- Alamandine via MrgD receptor attenuates pulmonary fibrosis via NOX4 and autophagy pathwayQingxia Liu, Bojun Zheng, Yue Zhang, Wenhui Huang, Qiaohui Hong, Ying Meng · 2021 · Canadian Journal of Physiology and Pharmacology
- [Retracted] Osthole Attenuates Bleomycin‐Induced Pulmonary Fibrosis by Modulating NADPH Oxidase 4‐Derived Oxidative Stress in MiceLijun Fang, Wei Wang, Jiazheng Chen, Anju Zuo, Hongmei Gao, Tao Yan, Pengqi Wang, Yujia Lu, Ruijuan Lv, Feng Xu et al. · 2021 · Oxidative Medicine and Cellular Longevity · Retracted
- Lung-Targeted Delivery of Dimethyl Fumarate Promotes the Reversal of Age-Dependent Established Lung FibrosisKosuke Kato, Ioannis Papageorgiou, Yoon-Joo Shin, Jennifer Kleinhenz, Sunny Palumbo, Seongmin Hahn, Joseph D. Irish, Skye P. Rounseville, Kenneth S. Knox, Louise Hecker · 2022 · Antioxidants
- Change in Nox4 expression is accompanied by changes in myogenic marker expression in differentiating C2C12 myoblastsS. Acharya, A. Mack Peters, Ann S. Norton, Gordon K. Murdoch, Rodney A. Hill · 2013 · Pflügers Archiv - European Journal of Physiology
- Innovative approaches to the therapy of fibrosisJoão A. de Andrade, Victor John Thannickal · 2009 · Current Opinion in Rheumatology
- A Positive Feed Forward Loop between Wnt/β-Catenin and NOX4 Promotes Silicon Dioxide-Induced Epithelial-Mesenchymal Transition of Lung Epithelial CellsJia Ma, Qian Cai, Dandan Yang, Jiali Yang, Jing Xue, Miao Yu, Yingxue Liu, Fucheng Ma, Feng Li, Xiaoming Liu · 2020 · Oxidative Medicine and Cellular Longevity
- Oxidative Stress and Pulmonary FibrosisMichelle L. Manni, Tim D. Oury · 2014 · Springer eBooks
- The Immunogenetics of Morphea and Lichen SclerosusPooya Khan Mohammad Beigi · 2022 · Advances in experimental medicine and biology
- Interleukin-6 blockade reduces salt-induced cardiac inflammation and fibrosis in subtotal nephrectomized miceHiroya Tanaka, Ting Sun, Hiroshi Kinashi, Keisuke Kamiya, Makoto Yamaguchi, Hironobu Nobata, Fumiko Sakata, Hangsoo Kim, Masashi Mizuno, Shunnosuke Kunoki et al. · 2022 · American Journal of Physiology-Renal Physiology
- NOX4 inhibition promotes the remodeling of dystrophic muscleDavid W. Hammers · 2022 · JCI Insight
- Cellular heterogeneity and plasticity during NAFLD progressionHyunju Park, Juyong Choi, Hyun-Mi Kim, Da-Yeon Yang, Tae Hyeon An, Eun‐Woo Lee, Baek‐Soo Han, Sang Chul Lee, Won Kon Kim, Kwang‐Hee Bae et al. · 2023 · Frontiers in Molecular Biosciences
- NOX4 Mediates Epithelial Cell Death in Hyperoxic Acute Lung Injury Through Mitochondrial Reactive Oxygen SpeciesAnantha K. Harijith, Prathima Basa, Alison W. Ha, Jaya Thomas, Anjum Jafri, Panfeng Fu, Peter Mathew MacFarlane, Thomas Michael Raffay, Viswanathan Natarajan, Tara Sudhadevi · 2022 · Frontiers in Pharmacology
- Reactive Oxygen Species as Mediators of Disease Progression and Therapeutic Response in Colorectal CancerNicholas Lyons, Rabina Giri, Jakob Begun, David A. Clark, David M. Proud, Yaowu He, John David Hooper, Thomas Kryza · 2023 · Antioxidants and Redox Signaling
- Bringing Light to Chronic Obstructive Pulmonary Disease Pathogenesis and ResilienceRubin M. Tuder · 2018 · Annals of the American Thoracic Society
- MicroRNA‑375 prevents TGF‑β‑dependent transdifferentiation of lung fibroblasts via the MAP2K6/P38 pathwayXinghua Zhang, Qian Chen, Hengya Song, Wanli Jiang, Songping Xie, Jie Huang, Ganjun Kang · 2020 · Molecular Medicine Reports
- NOX4 regulates macrophage apoptosis resistance to induce fibrotic progressionJennifer L. Larson‐Casey, Linlin Gu, Jungsoon Kang, A. Dhyani, A. Brent Carter · 2021 · Journal of Biological Chemistry
- NOX4 Is a Janus-Faced Reactive Oxygen Species Generating NADPH OxidaseHarald H.H.W. Schmidt, Kirstin Wingler, Christoph Kleinschnitz, G. J. Dusting · 2012 · Circulation Research
- Correlation between serum uric acid to high-density lipoprotein cholesterol ratio and atrial fibrillation in patients with NAFLDGaizhen Liu, Qi Zhang, Meng Zhou, Baojie Li, Jianqi Zhao, Rui Bai, Xiaosu Song, Weiwei Qin, Yonglai Zhang · 2024 · PLoS ONE
- NADPH oxidase 4 attenuates cerebral artery changes during the progression of Marfan syndromeYara Onetti, Thayna Meirelles, Ana Paula Dantas, Katrin Schröder, Elisabet Vila, Gustavo Egea, Francesc Jiménez‐Altayó · 2016 · American Journal of Physiology-Heart and Circulatory Physiology
- Amine oxidase activity regulates the development of pulmonary fibrosisFumiko Marttila‐Ichihara, Kati Elima, Kaisa Auvinen, Tibor Z. Veres, Pia Rantakari, Chris J. Weston, Masayuki Miyasaka, David Adams, Sirpa Jalkanen, Marko Salmi · 2017 · The FASEB Journal
- Trichodelphinine A alleviates pulmonary fibrosis by inhibiting collagen synthesis via NOX4-ARG1/TGF-β signaling pathwayFangle Liu, Yufeng Yao, Chengxi Guo, Pengyu Dai, Jinhao Huang, Peng Peng, Meiqi Wang, Zeren Dawa, Chenchen Zhu, Chaozhan Lin · 2024 · Phytomedicine
- Oxidative Stress and Endoplasmic Reticulum Stress in Rare Respiratory DiseasesMaría Magallón, Sara Pastor, Ana Carrión, Lucía Bañuls, Daniel Pellicer, Silvia Castillo, Sergio Bondía, María Mercedes Navarro‐García, Cruz González, Francisco Dası́ · 2021 · Journal of Clinical Medicine
- NADPH Oxidase 4 is required for interleukin-1β-mediated activation of protein kinase Cδ and downstream activation of c-Jun N-terminal kinase signaling in smooth muscleR. Ginnan, F. Jourd’heuil, Benjamin J. Guikema, Malorie Simons, H. Singer, D. Jourd’heuil · 2012 · Free Radical Biology & Medicine
- The Role of BRG1 in Antioxidant and Redox SignalingShilong You, Ying Zhang, Jiaqi Xu, Hao Ran Qian, Shaojun Wu, Boquan Wu, Saien Lu, Yingxian Sun, Naijin Zhang · 2020 · Oxidative Medicine and Cellular Longevity
- NADPH oxidase 4 is protective and not fibrogenic in intestinal inflammationEmily Stenke, Gabriella Aviello, Ashish Kumar Singh, Seán Martin, Des C. Winter, Brian Sweeney, Michael McDermott, Billy Bourke, Séamus Hussey, Ulla G. Knaus · 2020 · Redox Biology
- Manipulation of Redox Metabolism Using Pharmacologic Ascorbate Opens a Therapeutic Window for Radio-Sensitization by ATM Inhibitors in Colorectal CancerCameron Matthew Callaghan, Ibrahim M. Abukhiran, Amr H. Masaadeh, Richard V. Van Rheeden, Amanda L. Kalen, Samuel N. Rodman, Michael S. Petronek, Kranti A. Mapuskar, Benjamin N. George, Mitchell C. Coleman et al. · 2022 · International Journal of Radiation Oncology*Biology*Physics
- Identification of tyrosine brominated extracellular matrix proteins in normal and fibrotic lung tissuesLitiele Cezar Cruz, Aida Habibovic, Bianca Dempsey, Mariana Pereira Massafera, Yvonne M. W. Janssen-Heininger, Miao-Chong Joy Lin, Evan T. Hoffman, Daniel J. Weiss, Steven Kenneth Huang, Albert van der Vliet et al. · 2024 · Redox Biology
- Peroxidasin is a novel target of the redox-sensitive transcription factor Nrf2Kerry L. Hanmer, Demetra Mavri‐Damelin · 2018 · Gene
- Transforming growth factor β1-induced collagen production in myofibroblasts is mediated by reactive oxygen species derived from NADPH oxidase 4Yuma Hotta, Kazuhiko Uchiyama, Tomohisa Takagi, Saori Kashiwagi, Takahiro Nakano, Rieko Mukai, Yuki Toyokawa, Tomoyo Yasuda, Tomohiro Ueda, Yosuke Suyama et al. · 2018 · Biochemical and Biophysical Research Communications
- Transcriptome analysis reveals a protective role of liver X receptor alpha against silica particle-induced experimental silicosisWu Yao, Peiyan Yang, Yuanmeng Qi, Luheng Jin, Ahui Zhao, Mingcui Ding, Di Wang, Yiping Li, Changfu Hao · 2020 · The Science of The Total Environment
- Update in Diffuse Parenchymal Lung Disease 2009Oliver Eickelberg, Moisés Selman · 2010 · American Journal of Respiratory and Critical Care Medicine
- Novel mediators of idiopathic pulmonary fibrosisShigeki Saito, B. Deskin, Mohammad Rehan, Santosh Yadav, Yasuka Matsunaga, Joseph A. Lasky, Victor John Thannickal · 2022 · Clinical Science
- Metformin Attenuates TGF-β1-Induced Fibrosis in Salivary Gland: A Preliminary StudyLianhao Wang, Nian‐Nian Zhong, Xiaofeng Wang, Boyuan Peng, Zhuo Chen, Lili Wei, Bo Li, Yuhong Li, Yong Cheng · 2023 · International Journal of Molecular Sciences
- Downregulation of NOX4 Expression by Roflumilast N-Oxide Reduces Markers of Fibrosis in Lung FibroblastsDaniela Vecchio, Alessandra Acquaviva, Beatrice Arezzini, Hermann Tenor, Piero A. Martorana, Concetta Gardi · 2013 · Mediators of Inflammation
- Possible Role of NADPH Oxidase 4 in Angiotensin II-Induced Muscle Wasting in MiceTomoyasu Kadoguchi, Kazunori Shimada, Hiroshi Koide, Tetsuro Miyazaki, Tomoyuki Shiozawa, Shuhei Takahashi, Tatsuro Aikawa, Shohei Ouchi, Kenichi Kitamura, Yurina Sugita et al. · 2018 · Frontiers in Physiology
- Latest progress on the molecular mechanisms of idiopathic pulmonary fibrosisYue Fang, Jingya Tian, Yumei Fan, Pengxiu Cao · 2020 · Molecular Biology Reports
- Controlling pH by electronic ion pumps to fight fibrosisAnne Géraldine Guex, David J. Poxson, Daniel T. Simon, Magnus Berggren A, Giuseppino Fortunato, René Michel Rossi, Katharina Maniura‐Weber, Markus Rottmar · 2021 · Applied Materials Today
- NADPH oxidase-dependent heme oxygenase-1 expression mediates cigarette smoke-induced ferroptosis via intracellular Fe(II) accumulationOk‐Joo Sul, Seo Hee Park, Hye Won Choi, Dong Jun Kim, Seung Hwan Won · 2025 · Free Radical Biology and Medicine
- Crohn’s Strictures—Moving Away from the KnifeEmily Stenke, Billy Bourke, Ulla G. Knaus · 2017 · Frontiers in Pediatrics
- Understanding the Relationship between Glutathione, TGF-β, and Vitamin D in Combating Mycobacterium tuberculosis InfectionsMohkam Singh, Charles Vaughn, Kayvan Sasaninia, Christopher Yeh, Devanshi M. Mehta, Ibrahim Khieran, Vishwanath Venketaraman · 2020 · Journal of Clinical Medicine
- Effects of the Cytoplasm and Mitochondrial Specific Hydroxyl Radical Scavengers TA293 and mitoTA293 in Bleomycin-Induced Pulmonary Fibrosis Model MiceTakahiro Sakai, Hidetsugu Takagaki, Noriyuki Yamagiwa, Michio Ui, Shinichi Hatta, Jun Imai · 2021 · Antioxidants
- S-Glutathionylation-Controlled Apoptosis of Lung Epithelial Cells; Potential Implications for Lung FibrosisElizabeth Corteselli, Reem Aboushousha, Yvonne M. W. Janssen-Heininger · 2022 · Antioxidants
- Nicotinamide N-methyltransferase mediates lipofibroblast–myofibroblast transition and apoptosis resistanceMohammad Rehan, B. Deskin, Ashish Kurundkar, Santosh Yadav, Yasuka Matsunaga, Justin Manges, Nia Smith, K.G. Dsouza, Matthew E. Burow, Victor John Thannickal · 2023 · Journal of Biological Chemistry
- Pentaerythritol Tetranitrate Targeting Myocardial Reactive Oxygen Species Production Improves Left Ventricular Remodeling and Function in Rats With Ischemic Heart FailureDaniela Fraccarollo, Paolo Galuppo, Jonas Neuser, Johann K Bauersachs, Julian Daniel Widder · 2015 · Hypertension
- Oxidants in Acute and Chronic Lung DiseasePraveen Mannam · 2014 · Journal of Blood & Lymph
- Inflammasome as an Effective Platform for Fibrosis TherapyTingting Chen, Feng Xiao, Nan Li, Shan Shan, Meng Qi, Ziying Wang, Shengnan Zhang, Wei Wei, Wu‐Yi Sun · 2021 · Journal of Inflammation Research
- La voie Nrf2 en pathologie respiratoireAnne Boutten, Delphine Goven, Élise Artaud-Macari, Marcel Bonay · 2011 · médecine/sciences
- New treatment and markers of prognosis for idiopathic pulmonary fibrosis: lessons learned from translational researchEva Baroke, Jack Gauldie, Martin R.J. Kolb · 2013 · Expert Review of Respiratory Medicine
- Renal microRNA-144-3p is associated with transforming growth factor-β1-induced oxidative stress and fibrosis by suppressing the NRF2 pathway in hypertensive diabetic kidney diseaseSeung Ki Kim, Gwang Sun Bae, Taegeun Bae, Sae‐Kwang Ku, Bo-Hyun Choi, Mi‐Kyoung Kwak · 2024 · Free Radical Biology and Medicine
- Genome-scale modeling identifies dynamic metabolic vulnerabilities during the epithelial to mesenchymal transitionRupa Bhowmick, Scott Campit, Shiva Krishna Katkam, Venkateshwar G. Keshamouni, Sriram Chandrasekaran · 2024 · Communications Biology
- Pharmacological Inhibition of NOX4 Improves Mitochondrial Function and Survival in Human Beta-CellsAndris Elksnis, Jing Cen, Per Wikström, Per‐Ola Carlsson, Nils Welsh · 2021 · Biomedicines
- Selective Inhibition of Bromodomain-Containing Protein 4 Reduces Myofibroblast Transdifferentiation and Pulmonary FibrosisKsenija Bernau, Melissa E. Skibba, Jonathan P. Leet, S. Furey, Carson Gehl, Yi Li, Jia Zhou, Nathan K. Sandbo, Allan R. Brasier · 2022 · Frontiers in Molecular Medicine
- Docosahexaenoic acid (DHA) attenuated paraquat induced lung damage in miceJingjing Chen, Tao Zeng, Ye Bi, Zhixia Zhong, Keqin Xie, Xiulan Zhao · 2013 · Inhalation Toxicology
- Hyaluronidase-Loaded PLGA Microparticles as a New Strategy for the Treatment of Pulmonary FibrosisCláudia da Silva Bitencourt, Guilherme M. Gelfuso, Priscilla Aparecida Tártari Pereira, Patricia Aparecida de Assis, Cristiane Tefé‐Silva, Simone Gusmão Ramos, Eliane Candiani Arantes, Lúcia Helena Faccioli · 2014 · Tissue Engineering Part A
- NADPH Oxidase 4 Mediates TGFβ1-induced CCN2 in Gingival FibroblastsWenhao Yang, Yiting Deng, Y.P. Hsieh, King‐Jean Wu, Mark Yen‐Ping Kuo · 2015 · Journal of Dental Research
- TGFβ1 induces resistance of human lung myofibroblasts to cell death via down‐regulation of TRPA1 channelsHarvinder S Virk, Michael Biddle, Dawn T. Smallwood, Cathryn A. Weston, Emily Castells, Viona W. Bowman, Jamie McCarthy, Yassine Amrani, Stephen Mark Duffy, Peter H. Bradding et al. · 2021 · British Journal of Pharmacology
- Executable network of SARS-CoV-2-host interaction predicts drug combination treatmentsRowan S. M. Howell, Matthew A. Clarke, Ann‐Kathrin Reuschl, Tianyi Chen, Sean Abbott-Imboden, Mervyn Singer, David M. Lowe, Clare L. Bennett, Benny Chain, Clare L. Jolly et al. · 2022 · npj Digital Medicine
- Dynamic Interplay of Smooth Muscle α-Actin Gene-Regulatory Proteins Reflects the Biological Complexity of Myofibroblast DifferentiationArthur Roger Strauch, Seethalakshmi Hariharan · 2013 · Biology
- Oxidative/nitrative stress in the pathogenesis of systemic sclerosis: are antioxidants beneficial?Paul R. J. Ames, Tommaso Bucci, Mira Merashli, Marta Amaral, Alessia Arcaro, Fabrizio Gentile, Jaffar Nourooz‐Zadeh, José Delgado Alves · 2018 · Free Radical Research
- Intrahepatic microcirculatory disorder, parenchymal hypoxia and NOX4 upregulation result in zonal differences in hepatocyte apoptosis following lipopolysaccharide- and D-galactosamine-induced acute liver failure in ratsMasatake Tanaka, KOSUKE TANAKA, YUKO MASAKI, MASAYUKI MIYAZAKI, Masaki Kato, Kazuhiro Kotoh, Munechika Enjoji, Makoto Nakamuta, Ryoichi Takayanagi · 2013 · International Journal of Molecular Medicine
- Efferocytosis and enhanced FPR2 expression following apoptotic cell instillation attenuate radiation-induced lung inflammation and fibrosisSang Yeon Kim, Jin‐Mo Kim, Son Ro Lee, Hyun‐Jin Kim, Jae Hee Lee, Ho Lim Choi, Yoon‐Jin Lee, Yun‐Sil Lee, Jaeho Cho · 2022 · Biochemical and Biophysical Research Communications
- A novel caffeic acid derivative prevents angiotensin II-induced cardiac remodelingShih-Yi Lee, Yueh‐Hsiung Kuo, Chen-Xuan Du, Cheng-Wei Huang, Hui-Chun Ku · 2023 · Biomedicine & Pharmacotherapy
- Substrate-specific binding of 8-oxoguanine DNA glycosylase 1 (OGG1) reprograms mucosal adaptations to chronic airway injuryLang Pan, Spiros Vlahopoulos, Lloyd Tanner, Jesper Bergwik, Attila Bácsi, Zsolt O. Radak, Arne Egesten, Xueqing Ba, Allan R. Brasier, Istvan R. Boldogh · 2023 · Frontiers in Immunology
- Simvastatin attenuates silica-induced pulmonary inflammation and fibrosis in rats via the AMPK-NOX pathwayCunxiang Bo, Fang Liu, Zewen Zhang, Zhongjun Du, Haidi Xiu, Zhenling Zhang, Ming Li, Wei Zhang, Qiang Jia · 2024 · BMC Pulmonary Medicine
- Serum levels of nicotinamide-adenine dinucleotide phosphate oxidase 4 are associated with non-valvular atrial fibrillationTong Liu, Qingmiao Shao, Panagiotis G. Korantzopoulos, Enzhao Liu, Gang Xu, Guangping Li · 2015 · Biomedical Reports
- Age-dependent dysregulation of redox genes may contribute to fibrotic pulmonary disease susceptibilityEvan A. Elko, J. Matthew Mahoney, Pamela M. Vacek, Albert van der Vliet, Vikas Anathy, Jos L. J. van der Velden, Yvonne M. W. Janssen-Heininger, David Joseph Seward · 2019 · Free Radical Biology and Medicine
- AGE–RAGE Stress in the Pathophysiology of Atrial Fibrillation and Its TreatmentKailash Prasad · 2019 · International Journal of Angiology
- Modulation of COX-2 and NADPH oxidase-4 by alpha-lipoic acid ameliorates busulfan-induced pulmonary injury in ratsMona G. Elhadidy, Ahlam Elmasry, Hassan Reda Hassan Elsayed, Mohammad El-Nablaway, Shereen Mohamed Hamed, Mahmoud M. Elalfy, Mohammed R. Rabei · 2021 · Heliyon
- [Retracted] Progress of Statin Therapy in the Treatment of Idiopathic Pulmonary FibrosisLeiya Kou, Pei Kou, Guangwei Luo, Shuang Wei · 2022 · Oxidative Medicine and Cellular Longevity · Retracted
- CYB5R3 in type II alveolar epithelial cells protects against lung fibrosis by suppressing TGF-β1 signalingMarta Bueno, Jazmín Calyeca, Халиуллин Тимур Оскарович, Megan P. Miller, Diana Álvarez, Lorena Rosas, Judith Brands, Christian Baker, Amro Nasser, Stephanie Shulkowski et al. · 2023 · JCI Insight
- Dysregulated bidirectional epithelial–mesenchymal crosstalk: A core determinant of lung fibrosis progressionLiudi Yao, Zijian Xu, Donna E. Davies, Mark G. Jones, Yihua Wang · 2024 · Chinese Medical Journal - Pulmonary and Critical Care Medicine
- Endoplasmic Reticulum Oxidative Stress Promotes Glutathione-Dependent Oxidation of Collagen-1A1 and Promotes Lung Fibroblast ActivationJoseph E. Druso, Maximilian B. MacPherson, Shi Biao Chia, Evan A. Elko, Reem Aboushousha, David Joseph Seward, Hend Abdelhamid, Cuixia Shi Erickson, Elizabeth Corteselli, Megan Tarte et al. · 2024 · American Journal of Respiratory Cell and Molecular Biology
- Targeting Wnt Signaling to Improve Wound Healing After Myocardial InfarctionEvangelos P. Daskalopoulos, Ben J. Janssen, W. Matthijs Blankesteijn · 2013 · Methods in molecular biology
- Participation of NADPH 4 oxidase in thyroid regulationRomina Oglio, Leonardo A. Salvarredi, Luciano E. Rossich, Silvia Copelli, Mario Alberto Pisarev, Guillermo Juan Juvenal, Lisa Thomasz · 2018 · Molecular and Cellular Endocrinology