Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease

Ebrahimkhani, Mohammad R, Oakley, Fiona, Murphy, Lindsay B, Mann, Jelena, Moles, Anna, Perugorria, Maria J, Ellis, Elizabeth, Lakey, Anne F +7 more·2011·Nature Medicine
DOI 10.1038/nm.2490

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  9. 5-Hydroxytryptamine 2B receptor antagonism restores ATP and reduces tubulointerstitial fibrosis in the renal cortices of aged mice
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  10. Cross-talk between insulin and serotonin signaling in the brain : Involvement of the PI3K/Akt pathway and behavioral consequences in models of insulin resistance
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  11. L’autophagie macrophagique protège contre l'atteinte hépatique et la fibrose au cours de la maladie alcoolique du foie
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  12. Implication du métabolisme de la sérotonine dans les cancers du sein triple négatifs et perspectives cliniques
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  15. Cryo‐ EM Structures of the Human 5‐ HT 2B R Bound to Three Distinct Ligands Reveal Molecular Determinants of Subtype Selectivity
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  16. The Role of Gut Microbiota in Liver Regeneration After Partial Hepatectomy: New Evidence From Animal and Human Studies
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  17. Extracellular vesicles derived from Echinococcus granulosus hydatid cyst fluid may modulate liver fibrosis through 5-HT2B receptor
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  18. The role of tryptophan hydroxylase‐1 in metabolic dysfunction‐associated steatotic liver disease
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  19. Pharmacological antagonism of HTR2B reduces ERK and STAT3 activation and prevents renal fibrosis during the development of Adenine-Induced CKD in rats
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  20. BindingDB Entry 50047977: Structure-Based Scaffold Repurposing for G Protein-Coupled Receptors: Transformation of Adenosine Derivatives into 5HT
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  24. Insulin-sensitizing effects of Monascuspilosus ΔMpclr4 fermentation products: a strain- and time-dependent metabolomic and phenotypic study with candidate mwct echanisms
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