Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease

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Items 101–200 of 224

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7. Anti-Cholestatic Therapy with Obeticholic Acid Improves Short-Term Memory in Bile Duct-Ligated Mice
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11. Activation of liver stromal cells is associated with male-biased liver tumor initiation in xmrk and Myc transgenic zebrafish
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12. Serotonin: A key molecule in acute and chronic liver injury!
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14. Machine‐Learning Prediction of Oral Drug‐Induced Liver Injury (DILI) via Multiple Features and Endpoints
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15. Deregulated Serotonin Pathway in Women with Morbid Obesity and NAFLD
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18. Wnt2b attenuates HSCs activation and liver fibrosis through negative regulating TLR4 signaling
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19. Assessment of the possible roles of SB-269970 versus ketanserin on carbon tetrachloride-induced liver fibrosis in rats: Oxidative stress/TGF-β 1 -induced HSCs activation pathway
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24. Activated hepatic stellate cells: Negative regulators of hepatocyte proliferation in liver diseases
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28. Discovery of a peripheral 5HT2A antagonist as a clinical candidate for metabolic dysfunction-associated steatohepatitis
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32. Potent and Selective Human 5-HT2B Serotonin Receptor Antagonists: 4′-Cyano-(N)-methanocarba-adenosines by Synthetic Serendipity
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33. Accumulation of myeloid lineage cells is mapping out liver fibrosis post injury: a targetable lesion using Ketanserin
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34. Targeting the epithelial cells in fibrosis: a new concept for an old disease
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36. Targeting serotonin receptor 2B inhibits TGFβ induced differentiation of human vascular smooth muscle cells
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37. Sustained Isoprostane E2 Elevation, Inflammation and Fibrosis after Acute Ischaemia-Reperfusion Injury Are Reduced by Pregnane X Receptor Activation
    Aimen O. Amer, Philip M. E. Probert, Michael Dunn, Margaret Knight, Abigail E. Vallance, Paul Andrew Flecknell, Fiona Oakley, Iain Cameron, Steven Alan White, Peter G. Blain et al. · 2015 · PLoS ONE
38. Serotonin augments smooth muscle differentiation of bone marrow stromal cells
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39. Chronic restraint stress reduces carbon tetrachloride-induced liver fibrosis
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40. Characterization of non-coding variants associated with transcription-factor binding through ATAC-seq-defined footprint QTLs in liver
    Max F. Dudek, Brandon M. Wenz, Christopher D. Brown, Benjamin F. Voight, Laura A. Almasy, Struan F.A. Grant · 2025 · The American Journal of Human Genetics
41. Stellate Cells, Portal Myofibroblasts, and Epithelial-to-Mesenchymal Transition
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42. Hepatotoxicity of antipsychotics: an exploratory pharmacoepidemiologic and pharmacodynamic study integrating FAERS data and in vitro receptor-binding affinities
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43. Development of Pharmacophore Models for the Important Off-Target 5-HT2B Receptor
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44. New renal drug development to face chronic renal disease
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46. Serotonin: is it a marker for the diagnosis of hepatocellular carcinoma in cirrhotic patients?
    Hoda Aly Abd El Moety, Dalia Aly Maharem, Salwa H. Gomaa · 2013 · Alexandria Journal of Medicine
47. Gut-liver The role of serotonin and its pathways in hepatic fibrogenesis
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48. The Effects of Freshwater Clam (Corbicula fluminea) Extract on Activated Hepatic Stellate Cells
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49. Mdka produced by the activated HSCs drives bipotential progenitor cell redifferentiation during zebrafish biliary-mediated liver regeneration
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50. Altered serotonin metabolism in Takeda G protein-coupled receptor 5 knockout mice protects against diet-induced hepatic fibrosis
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51. Gene Structure, Expression, and 5-HT2B Receptor Signaling
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53. Serotonin-induced miR-221/222 contribute to the activation of hepatic stellate cells
    Yi Xiang, Yu‐Shui Ma, Ji‐Bin Liu, Zhijun Wu, Xiaoping Wang, Liping Liu, Gao‐Ren Wang, Da Fu, Wei Shi · 2020 · Biologia
54. Synthesis and Biological Evaluation of Peripheral 5HT2B Antagonists for Liver Fibrosis
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55. Sedum mexicanumBritt. Induces Apoptosis of Primary Rat Activated Hepatic Stellate Cells
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57. Structure activity relationships of 5-HT2B and 5-HT2C serotonin receptor antagonists: N6, C2 and 5′-Modified (N)-methanocarba-adenosine derivatives
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