Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell

Yui, Shiro, Nakamura, Tetsuya, Sato, Toshiro, Nemoto, Yasuhiro, Mizutani, Tomohiro, Zheng, Xiu, Ichinose, Shizuko, Nagaishi, Takashi +4 more·2012·Nature Medicine

DOI 10.1038/nm.2695

Cited by (805)

Items 201–300 of 805

Epithelial stem cells and intestinal cancer
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Organoid technologies meet genome engineering
Jing Nie, Eri Hashino · 2017 · EMBO Reports
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Application of CRISPR/Cas9 genome editing to the study and treatment of disease
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Organoid technology for brain and therapeutics research
Zhi Wang, Shu‐Na Wang, Tian‐Ying Xu, Zhu‐Wei Miao, Ding‐Feng Su, Chao‐Yu Miao · 2017 · CNS Neuroscience & Therapeutics
Organoid Models for Cancer Research
Hans C. Clevers, David A. Tuveson · 2019 · Annual Review of Cancer Biology
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Fredrik Holmberg, Jannie Pedersen, Peter Leth Jørgensen, Christoffer Soendergaard, Kim Bak Jensen, Ole Haagen Nielsen · 2017 · Journal of Tissue Engineering and Regenerative Medicine
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Yu Takahashi, Shintaro Sato, Yosuke Kurashima, Chen‐Yi Lai, Makoto Otsu, Mikio Hayashi, Takayuki Yamaguchi, Hiroshi Kiyono · 2017 · EBioMedicine
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Tao Xiang, Jie Wang, Hui Li · 2024 · Stem Cell Research & Therapy
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Yuli Wang, Asad A. Ahmad, Christopher E. Sims, Scott T. Magness, Nancy L. Allbritton · 2014 · Lab on a Chip
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Peter Jung, Christian Sommer, Francisco M. Barriga, Simon J. A. Buczacki, Xavier Hernando‐Momblona, Marta Sevillano, Miquel Duran‐Frigola, Patrick Aloy, Matthias Selbach, Douglas J. Winton et al. · 2015 · Stem Cell Reports
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Dianjun Qi, Wen Shi, Adrian R. Black, Mitchell A. Kuss, Xining Pang, Yini He, Bing Liu, Bin Duan · 2020 · Biomaterials
Ti 3 C 2 T x MXene Composite 3D Hydrogel Potentiates mTOR Signaling to Promote the Generation of Functional Hair Cells in Cochlea Organoids
Zhong Zhang, Shan Gao, Yangnan Hu, Xin Chen, Cheng Cheng, Xiaolong Fu, Sha‐Sha Zhang, Xin‐Lin Wang, Yu‐Wei Che, Chen Zhang et al. · 2022 · Advanced Science
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Yu Tan, Robert C. Coyle, Ryan W. Barrs, Sophia E. Silver, Mei Li, Dylan Richards, Yiliang Lin, Yuanwen Jiang, Hongjun Wang, Donald R. Menick et al. · 2023 · Science Advances
Development of a functional thyroid model based on an organoid culture system
Yoshiyuki Saito, Nobuyuki Onishi, Hiroshi E. Takami, Ryo Seishima, Hiroyoshi Inoue, Yuki Hirata, Kaori Kameyama, Kenji Tsuchihashi, Eiji Sugihara, Shinya Uchino et al. · 2018 · Biochemical and Biophysical Research Communications
Stem cell therapy for inflammatory bowel disease
Kanna Nagaishi, Yoshiaki Arimura, Mineko Fujimiya · 2015 · Journal of Gastroenterology
Long-term Inflammation Transforms Intestinal Epithelial Cells of Colonic Organoids
Shuji Hibiya, Kiichiro Tsuchiya, Ryohei Hayashi, Keita Fukushima, Nobukatsu Horita, Sho Watanabe, Tomoaki Shirasaki, Ryu Nishimura, Natsuko Kimura, Tatsunori Nishimura et al. · 2016 · Journal of Crohn s and Colitis
Cellular self-assembly and biomaterials-based organoid models of development and diseases
Shivem B. Shah, Ankur K. Singh · 2017 · Acta Biomaterialia
Contribution of Wound-Associated Cells and Mediators in Orchestrating Gastrointestinal Mucosal Wound Repair
Miguel Quirós, A. Nusrat · 2018 · Annual Review of Physiology
Innovative Therapeutic Strategies for Cystic Fibrosis: Moving Forward to CRISPR Technique
Michele Marangi, Giuseppa Pistritto · 2018 · Frontiers in Pharmacology
The role of intestinal stem cell within gut homeostasis: Focusing on its interplay with gut microbiota and the regulating pathways
Haoming Luo, Mingxing Li, Fang Wang, Yifei Yang, Qin Lin Wang, Yueshui Zhao, Fukuan Du, Yu Chen, Jing Shen, Qianyun Zhao et al. · 2022 · International Journal of Biological Sciences
An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate
Hansen, Stine L., Larsen, Hjalte L., Pikkupeura, Laura M., Maciag, Grzegorz, Guiu, Jordi, Müller, Iris, Clement, Ditte L., Mueller, Christina, Johansen, Jens Vilstrup, Helin, Kristian et al. · 2023 · Science Advances
Gastric Organoids: An Emerging Model System to Study Helicobacter pylori Pathogenesis
Malvika Pompaiah, Sina Bartfeld · 2017 · Current topics in microbiology and immunology
Intestinal Stem Cells to Advance Drug Development, Precision, and Regenerative Medicine: A Paradigm Shift in Translational Research
Jonathan Paul Mochel, Albert E. Jergens, Dawn D. Kingsbury, Hyun Jung Kim, Martı́n G. Martı́n, Karin Allenspach · 2017 · The AAPS Journal
Kidney organoids in translational medicine: Disease modeling and regenerative medicine
Tomoya Miyoshi, Ken Hiratsuka, Edgar Garcia Saiz, Ryuji Morizane · 2019 · Developmental Dynamics
Enhancing organoid culture: harnessing the potential of decellularized extracellular matrix hydrogels for mimicking microenvironments
Chen Li, Ni An, Qingru Song, Yuelei Hu, Wenzhen Yin, Qi Wang, Yinpeng Le, Wenting Pan, Xinlong Yan, Yunfang Wang et al. · 2024 · Journal of Biomedical Science
Progress in human liver organoids
Lulu Sun, Lijian Hui · 2020 · Journal of Molecular Cell Biology
Advancing Organoid Engineering for Tissue Regeneration and Biofunctional Reconstruction
Hairong Jin, Zengqi Xue, Jinnv Liu, Bin Ma, Jianfeng Yang, Lanjie Lei · 2024 · Biomaterials Research
Survival and Evolution of CRISPR–Cas System in Prokaryotes and Its Applications
Muhammad Abu Bakr Shabbir, Haihong Hao, Muhammad Zubair Shabbir, Hafiz Iftikhar Hussain, Iqbal Zahid, Saeed Ahmed, Adeel Sattar, Mujahid Iqbal, Jun Li, Zonghui Yuan · 2016 · Frontiers in Immunology
BMP signaling in homeostasis, transformation and inflammatory response of intestinal epithelium
Shan Wang, Ye‐Guang Chen · 2018 · Science China Life Sciences
Amelioration of DSS-induced murine colitis by VSL#3 supplementation is primarily associated with changes in ileal microbiota composition.
Jordan S. Mar, Nabeetha A. Nagalingam, Yuanlin Song, Michio Onizawa, Jae Woo Lee, Susan V. Lynch · 2014 · Gut Microbes
ER-stress mobilization of death-associated protein kinase-1–dependent xenophagy counteracts mitochondria stress–induced epithelial barrier dysfunction
Fernando Lopes, Åsa V. Keita, Alpana Saxena, Jose Luis Reyes, Nicole L. Mancini, Ala Al Rajabi, Arthur Wang, Cristiane Hatsuko Baggio, Michael S. Dicay, Rob van Dalen et al. · 2018 · Journal of Biological Chemistry
Salmonella enterica Serovar Typhimurium Exploits Cycling through Epithelial Cells To Colonize Human and Murine Enteroids
Petra Geiser, Maria Letizia Di Martino, Pilar Samperio Ventayol, Jens Eriksson, Eduardo Sima, Anas Kh. Al-Saffar, David Ahl, Mia Phillipson, Dominic‐Luc Webb, Magnus Sundbom et al. · 2021 · mBio
Scalable Production and Cryostorage of Organoids Using Core–Shell Decoupled Hydrogel Capsules
Lu, Yen‐Chun, Fu, Dah‐Jiun, An, Duo, Chiu, Alan, Schwartz, Robert, Nikitin, Alexander Yu., Ma, Minglin · 2017 · Advanced Biosystems
Long-term three-dimensional high-resolution imaging of live unlabeled small intestinal organoids via low-coherence holotomography
Mahn Jae Lee, Jaehyeok Lee, Jeongmin Ha, Geon Wu Kim, Hye‐Jin Kim, Sumin Lee, Bon‐Kyoung Koo, YongKeun Park · 2024 · Experimental & Molecular Medicine
Organoids and organoid extracellular vesicles-based disease treatment strategies
Guangyin Zhou, Ruiyang Li, Shihao Sheng, Jingtao Huang, Fengjin Zhou, Yan Wei, Han Liu, Jiacan Su · 2024 · Journal of Nanobiotechnology
Colorectal cancer models for novel drug discovery
Daniel M. Golovko, Dmitriy Kedrin, Ömer H. Yilmaz, Jatin Roper · 2015 · Expert Opinion on Drug Discovery
Stem cell therapy: an exercise in patience and prudence
Huan-Ting Lin, M. Otsu, H. Nakauchi · 2013 · Philosophical Transactions of the Royal Society B: Biological Sciences
Modeling human disease using organotypic cultures
Pawel J. Schweiger, Kim Bak Jensen · 2016 · Current Opinion in Cell Biology
Towards a defined ECM and small molecule based monolayer culture system for the expansion of mouse and human intestinal stem cells
Zhixiang Tong, Keir Martyn, Andy W. Yang, Xiaolei Yin, Benjamin E. Mead, Nitin Joshi, Nicholas E. Sherman, Róbert Langer, Jeffrey M. Karp · 2017 · Biomaterials
Organoids Reveal That Inherent Radiosensitivity of Small and Large Intestinal Stem Cells Determines Organ Sensitivity
M. Laura Martín, Mohammad Adileh, Kuo‐Shun Hsu, Guoqiang Hua, Sang Gyu Lee, Christy Li, John D. Fuller, Jimmy A. Rotolo, Sahra Bodo, Stefan Klingler et al. · 2019 · Cancer Research
The Contributions of Human Mini-Intestines to the Study of Intestinal Physiology and Pathophysiology
Huimin M. Yu, Nesrin M. Hasan, Julie In, Mary Kolb Estes, Olga N. Kovbasnjuk, Nicholas C. Zachos, Mark Donowitz · 2017 · Annual Review of Physiology
Through the Looking Glass: In Vitro Models for Inhalation Toxicology and Interindividual Variability in the Airway
Samantha C. Faber, Shaun D. McCullough · 2018 · Applied In Vitro Toxicology
Interleukin‑22 regulates the homeostasis of the intestinal epithelium during inflammation
Xinyan Zhang, Shijie Liu, Yueqian Wang, Huiqiong Hu, Liang Li, Yibin Wu, Duo Cao, Yuankun Cai, Jiqin Zhang, Xueli Zhang · 2019 · International Journal of Molecular Medicine
A bioengineering perspective on modelling the intestinal epithelial physiology in vitro
Maria Antfolk, Kim Bak Jensen · 2020 · Nature Communications
Organoids and regenerative hepatology
Nidhi Jalan‐Sakrikar, Teresa Brevini, Robert C. Huebert, Fotios Sampaziotis · 2022 · Hepatology
A Gutsy Task: Generating Intestinal Tissue from Human Pluripotent Stem Cells
Stacy R. Finkbeiner, Jason R. Spence · 2013 · Digestive Diseases and Sciences
Mesenchymal marker and LGR5 expression levels in circulating tumor cells correlate with colorectal cancer prognosis
Wuyi Wang, Lin Wan, Shiyang Wu, Jianguo Yang, Yang Zhou, Fang Liu, Zhengzheng Wu, Yong Cheng · 2018 · Cellular Oncology
Farm and Companion Animal Organoid Models in Translational Research: A Powerful Tool to Bridge the Gap Between Mice and Humans
Minae Kawasaki, Takashi Goyama, Yurika Tachibana, Itsuma Nagao, Yoko M. Ambrosini · 2022 · Frontiers in Medical Technology
Stem cell-derived cell cultures and organoids for protozoan parasite propagation and studying host–parasite interaction
Christian Klotz, Toni Aebischer, Frank Seeber · 2012 · International Journal of Medical Microbiology
Advanced three‐dimensional culture of equine intestinal epithelial stem cells
Amy Stieler Stewart, John M. Freund, Liara M. Gonzalez · 2017 · Equine Veterinary Journal
Potential Use of Human Stem Cell-Derived Intestinal Organoids to Study Inflammatory Bowel Diseases.
Isabella Dotti, Azucena Salas · 2018 · Europe PMC (PubMed Central)
Early injection of human adipose tissue-derived mesenchymal stem cell after inflammation ameliorates dextran sulfate sodium-induced colitis in mice through the induction of M2 macrophages and regulatory T cells
Yuzo Kawata, Atsunori Tsuchiya, Satoshi Seino, Yusuke Watanabe, Yuichi Kojima, Shunzo Ikarashi, Kentaro Tominaga, Junji Yokoyama, Satoshi Yamagiwa, Shuji Terai · 2019 · Cell and Tissue Research
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Konstantin J. Bode, Stefanie Mueller, Matthias Schweinlin, Marco Metzger, Thomas Brunner · 2019 · BioTechniques
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Maxime M. Mahé, Nambirajan Sundaram, Carey L. Watson, Noah F. Shroyer, Michael A. Helmrath · 2015 · Journal of Visualized Experiments
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Thomas A. Sebrell, Barkan Sidar, Rachel Bruns, Royce A. Wilkinson, Blake Wiedenheft, Paul J. Taylor, Brian A. Perrino, Linda C. Samuelson, James N. Wilking, Diane Bimczok · 2017 · Cell and Tissue Research
Intestinal organoids as tissue surrogates for toxicological and pharmacological studies
Anton Kuratnik, Charles A. Giardina · 2013 · Biochemical Pharmacology
Type 1 Diabetes and Dysfunctional Intestinal Homeostasis
Francesca D’Addio, Paolo Fiorina · 2016 · Trends in Endocrinology and Metabolism
ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases
Doaa Glal, Janaki N. Sudhakar, Hsueh-Han Lu, Ming-Che James Liu, Hung-Yu Chiang, Yen‐Chun Liu, Ching‐Feng Cheng, Jr‐Wen Shui · 2018 · Frontiers in Immunology
Defining hierarchies of stemness in the intestine: evidence from biomarkers and regulatory pathways
Adam D. Gracz, Scott T. Magness · 2014 · American Journal of Physiology-Gastrointestinal and Liver Physiology
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Deepthi Alapati, Edward E. Morrisey · 2016 · American Journal of Respiratory Cell and Molecular Biology
Long-term culture-induced phenotypic difference and efficient cryopreservation of small intestinal organoids by treatment timing of Rho kinase inhibitor
Sung-Hoon Han, Sehwan Shim, Minjung Kim, Hye‐Yun Shin, Won‐Suk Jang, Sun‐Joo Lee, Young-Woo Jin, Seung‐Sook Lee, Seung Bum Lee, Sunhoo Park · 2017 · World Journal of Gastroenterology
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Dušan Hrčkulák, Lucie Janečková, Lucie Lanikova, Vı́tězslav Křı́ž, Monika Horázná, Oľga Babošová, Martina Vojtěchová, Kateřina Galušková, Eva Šloncová, Vladimír Kořínek · 2018 · Genes
Investigation of infertility using endometrial organoids
Κωνσταντίνα Νικολακοπούλου, Margherita Yayoi Turco · 2021 · Reproduction
Advancement of Organoid Technology in Regenerative Medicine
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Alpana Saxena, Fernando Lopes, Karen Poon, Derek Mark McKay · 2017 · American Journal of Physiology-Gastrointestinal and Liver Physiology
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Edgar, Rachel D., Perrone, Francesca, Foster, April R., Payne, Felicity, Lewis, Sophia, Nayak, Komal M., Kraiczy, Judith, Cenier, Aurélie, Torrente, Franco, Salvestrini, Camilla et al. · 2022 · Cellular and Molecular Gastroenterology and Hepatology
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