Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B

Sun, Yu, Campisi, Judith, Higano, Celestia, Beer, Tomasz M, Porter, Peggy, Coleman, Ilsa, True, Lawrence, Nelson, Peter S·2012·Nature Medicine

Cited by (791)

Items 101–200 of 791

  1. Tumor microenvironment mechanisms and bone metastatic disease progression of prostate cancer
    Juening Kang, Federico La Manna, Francesco Bonollo, Natalie Sampson, Ian Alberts, Clemens Mingels, Ali Afshar‐Oromieh, George Niklaus Thalmann, Sofia Karkampouna · 2022 · Cancer Letters
  2. Physiological hypoxia restrains the senescence-associated secretory phenotype via AMPK-mediated mTOR suppression
    van Vliet, Thijmen, Varela-Eirin, Marta, Wang, Boshi, Borghesan, Michela, Brandenburg, Simone M., Franzin, Rossana, Evangelou, Konstantinos, Seelen, Marc, Gorgoulis, Vassilis, Demaria, Marco · 2021 · Molecular Cell
  3. SOX9 drives WNT pathway activation in prostate cancer
    Fen Ma, Huihui Ye, Housheng Hansen He, Sean J. Gerrin, Sen Chen, Benjamin Tanenbaum, Changmeng Cai, Adam G. Sowalsky, Lingfeng He, Hongyun Wang et al. · 2016 · Journal of Clinical Investigation
  4. Comprehensive review on how platinum- and taxane-based chemotherapy of ovarian cancer affects biology of normal cells
    Justyna Mikuła‐Pietrasik, Anna Witucka, Martyna Pakuła, Paweł Uruski, Beata Krasińska, Arkadiusz Andrzej Niklas, Andrzej Tykarski, Krzysztof Książek · 2018 · Cellular and Molecular Life Sciences
  5. The Role of Cancer-Associated Fibroblasts in Prostate Cancer Tumorigenesis
    Francesco Bonollo, George Niklaus Thalmann, Marianna Kruithof‐de Julio, Sofia Karkampouna · 2020 · Cancers
  6. Mathematical modeling of tumor-immune cell interactions
    Grace E. Mahlbacher, Kara C. Reihmer, Hermann B. Frieboes · 2019 · Journal of Theoretical Biology
  7. Overcoming the senescence‐associated secretory phenotype (SASP): a complex mechanism of resistance in the treatment of cancer
    Cecilia R. Chambers, Shona Ritchie, Brooke Pereira, Paul Timpson · 2021 · Molecular Oncology
  8. Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity
    Ilkow, Carolina S, Marguerie, Monique, Batenchuk, Cory, Mayer, Justin, Ben Neriah, Daniela, Cousineau, Sophie, Falls, Theresa, Jennings, Victoria A, Boileau, Meaghan, Bellamy, David et al. · 2015 · Nature Medicine
  9. Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination
    Yasuda, Tadahito, Koiwa, Mayu, Yonemura, Atsuko, Miyake, Keisuke, Kariya, Ryusho, Kubota, Sho, Yokomizo-Nakano, Takako, Yasuda-Yoshihara, Noriko, Uchihara, Tomoyuki, Itoyama, Rumi et al. · 2021 · Cell Reports
  10. Endothelial-cell FAK targeting sensitizes tumours to DNA-damaging therapy
    Tavora, Bernardo, Reynolds, Louise E., Batista, Silvia, Demircioglu, Fevzi, Fernandez, Isabelle, Lechertier, Tanguy, Lees, Delphine M., Wong, Ping-Pui, Alexopoulou, Annika, Elia, George et al. · 2014 · Nature
  11. Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging
    Muñoz, Denise P., Yannone, Steven M., Daemen, Anneleen, Sun, Yu, Vakar-Lopez, Funda, Kawahara, Misako, Freund, Adam M., Rodier, Francis, Wu, Jennifer D., Desprez, Pierre-Yves et al. · 2019 · JCI Insight
  12. Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells
    Tze‐Sian Chan, Chung‐Chi Hsu, Vincent C. Pai, Wen‐Ying Liao, Shenq‐Shyang Huang, Kok‐Tong Tan, Chia-Jui Yen, Shu-Ching Hsu, Wei‐Yu Chen, Yan‐Shen Shan et al. · 2016 · The Journal of Experimental Medicine
  13. MLL1 is essential for the senescence-associated secretory phenotype
    Capell, Brian C., Drake, Adam M., Zhu, Jiajun, Shah, Parisha P., Dou, Zhixun, Dorsey, Jean, Simola, Daniel F., Donahue, Greg, Sammons, Morgan, Rai, Taranjit Singh et al. · 2016 · Genes & Development
  14. Melatonin Anticancer Effects: Review
    Giuseppe Di Bella, Fabrizio Mascia, Luciano Gualano, Luigi Di Bella · 2013 · International Journal of Molecular Sciences
  15. Cancer-associated Fibroblast–promoted LncRNA DNM3OS Confers Radioresistance by Regulating DNA Damage Response in Esophageal Squamous Cell Carcinoma
    Hongfang Zhang, Yuhui Hua, Zhenzhen Jiang, Yue Jing, Ming Shi, Xiaoli Zhen, Xiaoyan Zhang, Ling Yang, Rongjing Zhou, Shixiu Wu · 2018 · Clinical Cancer Research
  16. The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1.
    Zhang, Boyi, Fu, Da, Xu, Qixia, Cong, Xianling, Wu, Chunyan, Zhong, Xiaoming, Ma, Yushui, Lv, Zhongwei, Chen, Fei, Han, Liu et al. · 2018 · Nature Communications
  17. Next-generation Sequencing of Advanced Prostate Cancer Treated with Androgen-deprivation Therapy
    Prabhakar Rajan, Ian M. Sudbery, M. Eugenia M. Villasevil, Ernest J. Mui, Janis Fleming, Mark Davis, Imran Ahmad, Joanne Edwards, Owen James Sansom, David Sims et al. · 2013 · European Urology
  18. Design of nanocarriers based on complex biological barriers in vivo for tumor therapy
    Junjie Liu, Menghuan Li, Zhong Yuan Luo, Liangliang Dai, Xingming Guo, Kaiyong Cai · 2017 · Nano Today
  19. Oxidative stress, cellular senescence and ageing
    Akshaj Pole, Manjari Dimri, Goberdhan P. Dimri · 2016 · AIMS molecular science
  20. CAF-secreted CXCL1 conferred radioresistance by regulating DNA damage response in a ROS-dependent manner in esophageal squamous cell carcinoma
    Hongfang Zhang, Jing Yue, Zhenzhen Jiang, Rongjing Zhou, Ruifei Xie, Yiping Xu, Shixiu Wu · 2017 · Cell Death and Disease
  21. Harnessing the tumor microenvironment: targeted cancer therapies through modulation of epithelial-mesenchymal transition
    Antonino Glaviano, Hannah Lau, Lukas M. Carter, E. Hui Clarissa Lee, Hiu Yan Lam, Elena Okina, Donavan Jia Jie Tan, Wency Tan, Hui Li Ang, Daniela Carbone et al. · 2025 · Journal of Hematology & Oncology
  22. Exploring the Tumor Microenvironment with Nanoparticles
    Lei Miao, Leaf Huang · 2015 · Cancer treatment and research
  23. Cancer Metastases to Bone: Concepts, Mechanisms, and Interactions with Bone Osteoblasts
    Alison B. Shupp, Alexus D. Kolb, Dimpi Mukhopadhyay, Karen M. Bussard · 2018 · Cancers
  24. The role of cellular senescence in skin aging and age-related skin pathologies
    Toby Chin, Xin Er Lee, Pei Yi Ng, Yaelim Lee, Oliver Dreesen · 2023 · Frontiers in Physiology
  25. Sorafenib resistance and JNK signaling in carcinoma during extracellular matrix stiffening
    Thuy V. Nguyen, Marianne Sleiman, Timothy Moriarty, William G. Herrick, Shelly R. Peyton · 2014 · Biomaterials
  26. Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD‐L1)‐mediated immunosuppression
    Qixia Xu, Qilai Long, Dexiang Zhu, Da Fu, Boyi Zhang, Liu Han, Min Qian, Jianming Guo, Jianmin Xu, Liu Cao et al. · 2019 · Aging Cell
  27. Tumor microenvironment-mediated chemoresistance in breast cancer
    Kobra Velaei, Nasser Samadi, Balal Brazvan, Jafar Soleimani Rad · 2016 · The Breast
  28. Tumour microenvironment responsive nanoconstructs for cancer theranostic
    Arif Gulzar, Jiating Xu, Chen Wang, Fei He, Dan Yang, Shili Gai, Piaoping Yang, Jun Lin, Dayong Jin, Bengang Xing · 2019 · Nano Today
  29. Manganese Dioxide Coated WS2@Fe3O4/sSiO2 Nanocomposites for pH‐Responsive MR Imaging and Oxygen‐Elevated Synergetic Therapy
    Guangbao Yang, Rui Zhang, Chao Liang, He Zhao, Xuan Yi, Sida Shen, Kai Yang, Liang Cheng, Zhuang Liu · 2017 · Small
  30. Senescence and the tumor-immune landscape: Implications for cancer immunotherapy
    Loretah Chibaya, Jarin T. Snyder, Marcus A. Ruscetti · 2022 · Seminars in Cancer Biology
  31. WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERThigh Prostate Cancer Stem Cells
    Kai Zhang, Yanjing Guo, Xue Wang, Huifang Zhao, Zhongzhong Ji, Chaping Cheng, Li Li, Yuxiang Fang, Dawei Xu, Helen He Zhu et al. · 2017 · Cancer Research
  32. A phase I study of niclosamide in combination with enzalutamide in men with castration-resistant prostate cancer
    Michael Thomas Schweizer, Kathleen L. Haugk, Jožefa S. McKiernan, Roman Gulati, Heather H. Cheng, Jessica L. Maes, Ruth F. Dumpit, Peter S. Nelson, Bruce Montgomery, Jeannine S. McCune et al. · 2018 · PLoS ONE
  33. Rutin is a potent senomorphic agent to target senescent cells and can improve chemotherapeutic efficacy
    Hanxin Liu, Qixia Xu, Halidan Wufuer, Zi Li, Rong Sun, Zhirui Jiang, Xuefeng Dou, Qiang Fu, Judith Campisi, Yu Sun · 2023 · Aging Cell
  34. Targeting Senescent Cells for a Healthier Aging: Challenges and Opportunities
    Song, Shuling, Tchkonia, Tamara, Jiang, Jing, Kirkland, James L., Sun, Yu · 2020 · Advanced Science
  35. The tumor microenvironment controls drug sensitivity
    Arne Östman · 2012 · Nature Medicine
  36. BRAF Inhibitors Induce Metastasis in RAS Mutant or Inhibitor-Resistant Melanoma Cells by Reactivating MEK and ERK Signaling
    Berta L. Sánchez‐Laorden, Amaya Virós, María Romina Girotti, Malin Pedersen, Grazia Saturno, Alfonso Zambon, Dan Niculescu‐Duvaz, Samra Turajlic, Andrew J Hayes, Martin Eric Gore et al. · 2014 · Science Signaling
  37. Targeting the adaptive molecular landscape of castration‐resistant prostate cancer
    Alexander William Wyatt, Martin Edwin Gleave · 2015 · EMBO Molecular Medicine
  38. Combinatorial prospects of nano-targeted chemoimmunotherapy
    Candido G. Da Silva, Félix Rueda, Clemens W.G.M. Löwik, FERRY A. OSSENDORP, Luis Javier Cruz · 2016 · Biomaterials
  39. Cisplatin-activated PAI-1 secretion in the cancer-associated fibroblasts with paracrine effects promoting esophageal squamous cell carcinoma progression and causing chemoresistance
    Yun Che, Jingnan Wang, Yuan Li, Zhiliang Lu, Jianbing Huang, Shouguo Sun, Shuangshuang Mao, Yuanyuan Lei, Ruochuan Zang, Nan Sun et al. · 2018 · Cell Death and Disease
  40. Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies
    Go J. Yoshida, Arata Azuma, Yukiko Miura, Akira Orimo · 2019 · International Journal of Molecular Sciences
  41. Charge-reversal nanocarriers: An emerging paradigm for smart cancer nanomedicine
    Mingzhen Zhang, Xiaoxiao Chen, Chao Li, Xian Shen · 2019 · Journal of Controlled Release
  42. Cancer-Associated Fibroblasts: Versatile Players in the Tumor Microenvironment
    Debolina Ganguly, Raghav Chandra, John D. Karalis, Martha E. Teke, Todd Anthony Aguilera, Ravikanth Maddipati, Megan Wachsmann, Dario Ghersi, Giulia Siravegna, Herbert J. Zeh et al. · 2020 · Cancers
  43. Inflammation in cancer: therapeutic opportunities from new insights
    Yifei Xie, Fangfang Liu, Yunfei Wu, Yuer Zhu, Yanan Jiang, Qiong Wu, Zigang Dong, Kangdong Liu · 2025 · Molecular Cancer
  44. Tumour Cell Heterogeneity
    Laura J. Gay, Ann‐Marie Baker, Trevor A. Graham · 2016 · F1000Research
  45. The roles of tumor- and metastasis-promoting carcinoma-associated fibroblasts in human carcinomas
    Yoshihiro Mezawa, Akira Orimo · 2016 · Cell and Tissue Research
  46. Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2
    Stephen B. Keysar, Phuong N. Le, Bettina Miller, Brian C. Jackson, Justin R. Eagles, Cera Nieto, Jihye Kim, Binwu Tang, Magdalena J. Glogowska, J. Jason Morton et al. · 2016 · JNCI Journal of the National Cancer Institute
  47. Targeting SPINK1 in the damaged tumour microenvironment alleviates therapeutic resistance
    Fei Chen, Qilai Long, Da Fu, Dexiang Zhu, Yan Ji, Liu Han, Boyi Zhang, Qixia Xu, Bingjie Liu, Yan Li et al. · 2018 · Nature Communications
  48. Integrative spatial analysis of cell morphologies and transcriptional states with MUSE
    Feng Bao, Yue Cheng Deng, Sen Wan, Susan Q. Shen, Bo Wang, Qionghai Dai, Steven J. Altschuler, Lani F. Wu · 2022 · Nature Biotechnology
  49. Senescence in cancer
    Manuel Colucci, Miles Sarill, Martino Maddalena, Aurora Valdata, Martina Troiani, Martina Massarotti, Marco Bolis, Silvia Bressan, Anna Kohl, Daniele Robesti et al. · 2025 · Cancer Cell
  50. Studying cancer immunotherapy using patient-derived xenografts (PDXs) in humanized mice
    Yunsik Choi, Sanghyuk Lee, Kapyoul Kim, Soo Hyun Kim, Yeun‐Jun Chung, Charles Lee · 2018 · Experimental & Molecular Medicine
  51. Targeting the Interplay Between Cancer Fibroblasts, Mesenchymal Stem Cells, and Cancer Stem Cells in Desmoplastic Cancers
    Tze‐Sian Chan, Yuval Shaked, Kelvin K. Tsai · 2019 · Frontiers in Oncology
  52. Pharmacological CDK4/6 inhibition reveals a p53‐dependent senescent state with restricted toxicity
    Wang, Boshi, Varela‐Eirin, Marta, Brandenburg, Simone M, Hernandez‐Segura, Alejandra, van Vliet, Thijmen, Jongbloed, Elisabeth M, Wilting, Saskia M, Ohtani, Naoko, Jager, Agnes, Demaria, Marco · 2022 · The EMBO Journal
  53. Nanoparticle modulation of the tumor microenvironment enhances therapeutic efficacy of cisplatin
    Lei Miao, Yuhua Wang, C. Michael Lin, Yang Xiong, Naihan Chen, Lu Zhang, William Y. Kim, Leaf Huang · 2015 · Journal of Controlled Release
  54. Of Flies, Mice, and Men: Evolutionarily Conserved Tissue Damage Responses and Aging
    Joana Neves, Marco Demaria, Judith Campisi, Heinrich Jasper · 2015 · Developmental Cell
  55. Human cancer-associated fibroblasts enhance glutathione levels and antagonize drug-induced prostate cancer cell death
    Emarndeena Haji Cheteh, Martin Augsten, Helene Rundqvist, Julie Bianchi, Victoria Sarne, Lars Egevad, Vladimir J.N. Bykov, Arne Östman, Klas G. Wiman · 2017 · Cell Death and Disease
  56. What can be learned from a chaotic cancer model?
    Christophe Letellier A, Fabrice Denis, Luís A. Aguirre · 2013 · Journal of Theoretical Biology
  57. DDR-mediated crosstalk between DNA-damaged cells and their microenvironment
    Nicolas Malaquin, Audrey Carrier-Leclerc, Mireille Dessureault, Françis Rodier · 2015 · Frontiers in Genetics
  58. RETRACTED ARTICLE: SFRP2 augments WNT16B signaling to promote therapeutic resistance in the damaged tumor microenvironment
    Yu Sun, Dexiang Zhu, F Chen, Min Qian, Haifeng Wei, W Chen, Jinhua Xu · 2016 · Oncogene · Retracted
  59. Revisiting the role of Wnt/β-catenin signaling in prostate cancer
    Jeffrey A. Schneider, Susan K. Logan · 2017 · Molecular and Cellular Endocrinology
  60. Metformin reverses prostate cancer resistance to enzalutamide by targeting TGF-β1/STAT3 axis-regulated EMT
    Qiuli Liu, Dali Tong, Gaolei Liu, Jing Xu, Khang Do, Kyla R. Geary, Dianzheng Zhang, Jun Zhang, Yao Zhang, Yaoming Li et al. · 2017 · Cell Death and Disease
  61. Tumor Microenvironment as a Regulator of Radiation Therapy: New Insights into Stromal-Mediated Radioresistance
    Varintra E. Krisnawan, Jennifer Anne Stanley, Julie Kristina Schwarz, David G. DeNardo · 2020 · Cancers
  62. Cisplatin-induced CCL5 secretion from CAFs promotes cisplatin-resistance in ovarian cancer via regulation of the STAT3 and PI3K/Akt signaling pathways
    Bo Zhou, Chaoyang Sun, Na Li, Wanying Shan, Hao Lü, Lili Guo, Ensong Guo, Meng Xia, DANHUI WENG, Meng Li et al. · 2016 · International Journal of Oncology
  63. Altered p53 functionality in cancer-associated fibroblasts contributes to their cancer-supporting features
    Sharathchandra Arandkar, Noa Furth, Yair Elisha, Nishanth Belugali Nataraj, Heiko van der Kuip, Yosef Yarden, Walter E. Aulitzky, Igor Ulitsky, Benjamin Geiger, Moshe Oren · 2018 · Proceedings of the National Academy of Sciences
  64. Determinants and functions of CAFs secretome during cancer progression and therapy
    Linares, Jenniffer, Marín-Jiménez, Juan A., Badia-Ramentol, Jordi, Calon, Alexandre · 2021 · Frontiers in Cell and Developmental Biology
  65. Quercetin and doxorubicin co-delivery using mesoporous silica nanoparticles enhance the efficacy of gastric carcinoma chemotherapy
    Jian Fang, Shangwu Zhang, Xiaofeng Xue, Xinguo Zhu, Shiduo Song, Bin Wang, Lin‐Hua Jiang, Mingde Qin, Hansi Liang, Ling Gao · 2018 · International Journal of Nanomedicine
  66. Sequential delivery of nanoformulated α-mangostin and triptolide overcomes permeation obstacles and improves therapeutic effects in pancreatic cancer
    Jingxian Feng, Minjun Xu, Jiahao Wang, Songlei Zhou, Yipu Liu, Shanshan Liu, Yukun Huang, Yu Chen, Chen Liang, Qingxiang Song et al. · 2020 · Biomaterials
  67. The impact of tumor stroma on drug response in breast cancer
    Jürgen Dittmer, Benjamin Leyh · 2014 · Seminars in Cancer Biology
  68. Intersection of AHR and Wnt Signaling in Development, Health, and Disease
    Andrew J. Schneider, Amanda M. Branam, Richard E. Peterson · 2014 · International Journal of Molecular Sciences
  69. The role of Wnt signaling pathway in tumor metabolic reprogramming
    Yongzhen Mo, Yumin Wang, Lishen Zhang, Liting Yang, Ming Zhou, Xiaoling Li, Yong Li, Guiyuan Li, Zhaoyang Zeng, Wei Xiong et al. · 2019 · Journal of Cancer
  70. To clear, or not to clear (senescent cells)? That is the question
    Lujambio, Amaia · 2016 · BioEssays
  71. An autocrine inflammatory forward-feedback loop after chemotherapy withdrawal facilitates the repopulation of drug-resistant breast cancer cells
    Jia, Deyong, Li, Li, Andrew, Sulaiman, Allan, David, Li, Xuguang, Lee, Jonathan, Ji, Guang, Yao, Zemin, Gadde, Suresh, Figeys, Danial et al. · 2017 · Cell Death & Disease
  72. Stress management by autophagy: Implications for chemoresistance
    Zhao Huang, Li Zhou, Zhibin Chen, Edouard Collins Nice, Canhua Huang · 2016 · International Journal of Cancer
  73. Recent advances in nanoparticle carriers for photodynamic therapy
    Gawon Yi, Suk ho Hong, Jihwan Son, Jihye Yoo, Changhee Park, Yongdoo Choi, Heebeom Koo · 2018 · Quantitative Imaging in Medicine and Surgery
  74. The extracellular matrix alteration, implication in modulation of drug resistance mechanism: friends or foes?
    Ancuta Maria Jurj, Călin Ionescu, Ioana Berindan‐Neagoe, Cornelia Braicu · 2022 · Journal of Experimental & Clinical Cancer Research
  75. Mesenchymal stromal cells derived from acute myeloid leukemia bone marrow exhibit aberrant cytogenetics and cytokine elaboration
    Joe Chin-Sun Huang, Soumit K. Basu, Xueqin Zhao, S Chien, Min Fang, Vivian G. Oehler, Frederick R. Appelbaum, Pamela Sue Becker · 2015 · Blood Cancer Journal
  76. Inhibition of androgen receptor and β-catenin activity in prostate cancer
    Eugine Lee, Aviv Madar, Gregory David, Michael J. Garabedian, Ramanuj DasGupta, Susan K. Logan · 2013 · Proceedings of the National Academy of Sciences
  77. Paracrine tumor signaling induces transdifferentiation of surrounding fibroblasts.
    P. Heneberg · 2016 · Critical reviews in oncology/hematology
  78. Tie2 Expression on Macrophages Is Required for Blood Vessel Reconstruction and Tumor Relapse after Chemotherapy
    Lin Chen, Jie Li, Fei Wang, Chengliang Dai, Fan Wu, Xiaoman Liu, Taotao Li, Rainer Glauben, Yi Zhang, Guangjun Nie et al. · 2016 · Cancer Research
  79. Tumor microenvironment remodeling-based penetration strategies to amplify nanodrug accessibility to tumor parenchyma
    Yanhong Liu, Jiyuan Zhou, Qiang Li, Lingchao Li, Yue Jia, Feiyang Geng, Jianping Zhou, Tingjie Yin · 2021 · Advanced Drug Delivery Reviews
  80. Tumor-Associated Fibroblast-Targeted Regulation and Deep Tumor Delivery of Chemotherapeutic Drugs with a Multifunctional Size-Switchable Nanoparticle
    Xingli Cun, Jiantao Chen, Mengmeng Li, Xuan He, Xian Tang, Rong Hua Guo, Miao Deng, Man Li, Zhirong Zhang, Qin He · 2019 · ACS Applied Materials & Interfaces
  81. The tumor microenvironment shapes hallmarks of mature B-cell malignancies
    Kenneth H. Shain, William S. Dalton, Jianguo Tao · 2015 · Oncogene
  82. Cellular Constituents of the Prostate Stroma: Key Contributors to Prostate Cancer Progression and Therapy Resistance
    Christine Levesque, Peter S. Nelson · 2017 · Cold Spring Harbor Perspectives in Medicine
  83. Metformin Suppresses Tumor Progression by Inactivating Stromal Fibroblasts in Ovarian Cancer
    Sen Xu, Zongyuan Yang, Ping Jin, Xin Yang, Xiaoting Li, Wei Xiao, Ya Wang, Sixiang Long, Taoran Zhang, Gang Chen et al. · 2018 · Molecular Cancer Therapeutics
  84. Carbon dots for cancer nanomedicine: a bright future
    Samer Bayda, Emanuele Amadio, Simone Cailotto, Yahima Frión-Herrera, Alvise Perosa, Flavio Rizzolio · 2021 · Nanoscale Advances
  85. Tumor microenvironment and cellular senescence: Understanding therapeutic resistance and harnessing strategies
    Hanxin Liu, Huifang Zhao, Yu Sun · 2021 · Seminars in Cancer Biology
  86. Advances of Wnt Signalling Pathway in Colorectal Cancer
    Yaoyao Zhu, Xia Li · 2023 · Cells
  87. Cellular senescence of renal tubular epithelial cells in acute kidney injury
    Juan Chen, Huhai Zhang, Xiangling Yi, Qian Dou, Xin Yang, Jia Chen, Jia Chen, Kehong Chen · 2024 · Cell Death Discovery
  88. Elevated CXCL1 expression in breast cancer stroma predicts poor prognosis and is inversely associated with expression of TGF-β signaling proteins
    An Zou, Diana L. Lambert, Hung‐Wen Yeh, Ken Yasukawa, Fariba Behbod, Fang Fan, Nikki Cheng · 2014 · BMC Cancer
  89. CXCL1-LCN2 paracrine axis promotes progression of prostate cancer via the Src activation and epithelial-mesenchymal transition
    Yongning Lu, Baijun Dong, Fan Xu, Yunze Xu, Jiahua Pan, Jiajia Song, Jin Zhang, Yong Huang, Wei Xue · 2019 · Cell Communication and Signaling
  90. How tumor growth can be influenced by delayed interactions between cancer cells and the microenvironment?
    Dibakar Ghosh, Subhas Khajanchi, Sylvain Mangiarotti, Fabrice Denis, Syamal K. Dana, Christophe Letellier A · 2017 · Biosystems
  91. RETRACTED: Senescent Stromal Cells Promote Cancer Resistance through SIRT1 Loss-Potentiated Overproduction of Small Extracellular Vesicles
    Liu Han, Qilai Long, Shenjun Li, Qixia Xu, Boyi Zhang, Xuefeng Dou, Min Qian, Yannasittha Jiramongkol, Jianming Guo, Liu Cao et al. · 2020 · Cancer Research · Retracted
  92. Curcumin Inhibits Gastric Carcinoma Cell Growth and Induces Apoptosis by Suppressing the Wnt/β-Catenin Signaling Pathway
    Ruzhen Zheng, Qinghua Deng, Yuehua Liu, Pengjun Zhao · 2017 · Medical Science Monitor
  93. Cancer secretome and inflammation: The bright and the dark sides of NF-κB
    Daria Capece, Daniela Verzella, Alessandra Tessitore, Edoardo Alesse, Carlo Capalbo, Francesca Zazzeroni · 2017 · Seminars in Cell and Developmental Biology
  94. Mangiferin functionalized radioactive gold nanoparticles (MGF- 198 AuNPs) in prostate tumor therapy: green nanotechnology for production, in vivo tumor retention and evaluation of therapeutic efficacy
    Amal Yousif Al-Yasiri, Menka Khoobchandani, C. Cutler, Lisa D. Watkinson, Terry L. Carmack, Charles Jeffrey Smith, Marina Kuchuk, Sudarshan K. Loyalka, Ademar B. Lugão, Kattesh V. Katti · 2017 · Dalton Transactions
  95. Emerging Nano Drug Delivery Systems Targeting Cancer-Associated Fibroblasts for Improved Antitumor Effect and Tumor Drug Penetration
    Jian Xin Guo, Huating Zeng, Yan Chen · 2020 · Molecular Pharmaceutics
  96. Stromal epigenetic dysregulation is sufficient to initiate mouse prostate cancer via paracrine Wnt signaling
    Yang Zong, Jiaoti Huang, Devipriya Sankarasharma, Teppei Morikawa, Masashi Fukayama, Jonathan I. Epstein, Kiran K. Chada, Owen N. Witte · 2012 · Proceedings of the National Academy of Sciences
  97. Functional diversity of cancer‐associated fibroblasts in modulating drug resistance
    Luke Bu, Hideo Baba, Tadahito Yasuda, Tomoyuki Uchihara, Takatsugu Ishimoto · 2020 · Cancer Science
  98. TRPC3 shapes the ER-mitochondria Ca2+ transfer characterizing tumour-promoting senescence
    Valério Farfariello, Dmitri V. Gordienko, Lina Mesilmany, Yasmine S. Touil, Emmanuelle Germain, Ingrid Fliniaux, Emilie Desruelles, Dimitra Gkika, Morad M. Roudbaraki, George Shapovalov et al. · 2022 · Nature Communications
  99. Parallel microfluidic chemosensitivity testing on individual slice cultures
    Tim C. Chang, Andrei M. Mikheev, Wilson Huynh, Raymond J. Monnat, Robert Rostomily, Albert Folch · 2014 · Lab on a Chip
  100. Chemotherapy induces expression and release of heparanase leading to changes associated with an aggressive tumor phenotype
    Vishnu C. Ramani, Israël Vlodavsky, Mary Ng, Yi Zhang, Paola Barbieri, Alessandro Noseda, Ralph D. Sanderson · 2016 · Matrix Biology