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Prognosis and Immunotherapy Significances of a Cancer-Associated Fibroblasts-Related Gene Signature in Gliomas

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Endocannabinoid System and Tumour Microenvironment: New Intertwined Connections for Anticancer Approaches

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The Convergence of FTIR and EVs: Emergence Strategy for Non-Invasive Cancer Markers Discovery

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Unraveling the intricacies of cancer‐associated fibroblasts: a comprehensive review on metabolic reprogramming and tumor microenvironment crosstalk

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Recombinant Viral Vectors for Therapeutic Programming of Tumour Microenvironment: Advantages and Limitations

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CAFs vs. TECs: when blood feuds fuel cancer progression, dissemination and therapeutic resistance

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Precision Targeting Strategies in Pancreatic Cancer: The Role of Tumor Microenvironment

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Nano-Drug Delivery Systems Targeting CAFs: A Promising Treatment for Pancreatic Cancer

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MicroRNAs in Hepatocellular Carcinoma Pathogenesis: Insights into Mechanisms and Therapeutic Opportunities

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Weakly migratory metastatic breast cancer cells activate fibroblasts via microvesicle-Tg2 to facilitate dissemination and metastasis

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IFN γ and TNF α drive an inflammatory secretion profile in cancer‐associated fibroblasts from human non‐small cell lung cancer

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Peptide–Platinum(IV) Conjugation Minimizes the Negative Impact of Current Anticancer Chemotherapy on Nonmalignant Cells

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Musashi-2 in cancer-associated fibroblasts promotes non-small cell lung cancer metastasis through paracrine IL-6-driven epithelial-mesenchymal transition

Samart, P., Palliyage, G. H., Issaragrisil, S., Luanpitpong, S., & Rojanasakul, Y. (2023) · Cell & Bioscience · doi:10.1186/s13578-023-01158-5 · Cited by 16 · see citing works

In Vitro Effect of Δ9-Tetrahydrocannabinol and Cannabidiol on Cancer-Associated Fibroblasts Isolated from Lung Cancer

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Exosome-Derived Non-Coding RNAs in the Tumor Microenvironment of Colorectal Cancer: Possible Functions, Mechanisms and Clinical Applications

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Targeting CAFs and extracellular matrix (ECM) in lung cancer: Potential of adjuvants and nanoparticles

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FGFR4 promotes CAF activation through the CXCL10-CXCR3 axis in colon cancer

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3D printing to construct in vitro multicellular models of melanoma

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The tumor microenvironment: adding pieces to the puzzle

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miR-200-mediated inactivation of cancer-associated fibroblasts via targeting of NRP2-VEGFR signaling attenuates lung cancer invasion and metastasis

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Exploring the multifaceted role of direct interaction between cancer cells and fibroblasts in cancer progression

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Differential roles of normal and lung cancer-associated fibroblasts in microvascular network formation

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Valsartan as a prophylactic treatment against breast cancer development and niche activation: What molecular sequels follow chronic AT-1R blockade?

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Mechanistic role of stromal cancer-associated fibroblasts in tumorigenesis and brain metastasis: Highlighting drug resistance and targeted therapy

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Tumor microenvironment in non-melanoma skin cancer resistance to photodynamic therapy

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Assessing the epithelial-to-mesenchymal plasticity in a small cell lung carcinoma (SCLC) and lung fibroblasts co-culture model

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Tumor Microenvironmental Cytokines Drive NSCLC Cell Aggressiveness and Drug-Resistance via YAP-Mediated Autophagy

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Proteomic profiling identifies a stromal TGF-β1/podoplanin axis as a driver of colorectal cancer progression

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Cancer-associated fibroblasts in osteosarcoma: key players in immune escape and targeted therapy

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Critical Contribution of Various Signaling Pathways in the Development of Drug Resistance in Colorectal Cancer: An Update

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Single-cell aggrephagy-related patterns facilitate tumor microenvironment intercellular communication, influencing osteosarcoma progression and prognosis

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TiME for a change: The tumor microenvironment as the missing piece in cancer therapeutics

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Rimonabant and Cannabidiol Rewrite the Interactions between Breast Cancer Cells and Tumor Microenvironment

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The anti-neoplastic effects of metformin modulate the acquired phenotype of fibroblast cells in the breast cancer-normal fibroblast co-culture system

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LOX+ iCAFs in HNSCC have the potential to predict prognosis and immunotherapy responses revealed by single cell RNA sequencing analysis

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TRIM16 mediates secretory autophagy in head and neck cancer-associated fibroblasts

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HSF2 drives breast cancer progression by acting as a stage-specific switch between proliferation and invasion

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DNA Damage Responses in Tumors Are Not Proliferative Stimuli, but Rather They Are DNA Repair Actions Requiring Supportive Medical Care

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Oral Squamous Cell Carcinoma-Derived ANGPTL3 Induces Cancer Associated Fibroblastic Phenotypes in Surrounding Fibroblasts

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The use of a multi-metric readout screen to identify EHMT2/G9a-inhibition as a modulator of cancer-associated fibroblast activation state

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ECM‐Stiffness Mediated Persistent Fibroblast Activation Requires Integrin and Formin Dependent Chromatin Remodeling

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Re-Shaping the Pancreatic Cancer Tumor Microenvironment: A New Role for the Metastasis Suppressor NDRG1

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Stromal transcriptomics uncover LIF as a key effector in high tumor budding triple-negative breast cancer

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Estrogen Regulated Genes Compel Apoptosis in Breast Cancer Cells, Whilst Stimulate Antitumor Activity in Peritumoral Immune Cells in a Janus-Faced Manner

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Dynamic HSF2 regulation drives breast cancer progression by steering the balance between proliferation and invasionPreprint

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Stromal biomarker-based framework for identifying pMMR/MSS and dMMR/MSI colorectal cancers with poor outcomes and limited benefit from immunotherapy

Iglesias, M., Badia-Ramentol, J., Martínez‐Ciarpaglini, C., Linares, J., Tarazona, N., Mulet-Margalef, N., Tornero-Piñero, P., Sallent-Aragay, A., Recort-Bascuas, A., Gibert, J., et al. (2026) · Gut · doi:10.1136/gutjnl-2025-336804 · Cited by 3 · see citing works

Unveiling immune cell response disparities in human primary cancer-associated fibroblasts between two- and three-dimensional cultures

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Fibroblasts activated by miRs-185-5p, miR-652-5p, and miR-1246 shape the tumor microenvironment in triple-negative breast cancer via PATZ1 downregulation

Luca, G. D., Petrillo, G., Scognamiglio, I., Pane, K., Cocca, L., Roscigno, G., Mascolo, M., Pignataro, C., Verde, S., Fraticelli, A., et al. (2025) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-025-05781-y · Cited by 3 · see citing works

Tumor Microenvironment: Multiway Role in Drug Resistance

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Biophysical Regulation of TGFβ Signaling in the Tumor Microenvironment

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Decoding the mechanical language of the tumor microenvironment: From physical forces to malignant behaviors

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Fibroblasts Promote Resistance to KRAS Silencing in Colorectal Cancer Cells

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Elucidating the mechanistic role of ovarian cancer biomarkers: Lessons learnt from affinity-proteomics

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The Role of Inflammatory Cells in Tumor Angiogenesis

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Effects of mitotically active polyploid giant cancer cells on chemoresistance through interaction with cancer-associated fibroblasts

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A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

Carter, A. T., Fabiano, A. R., Aalaei, E., Deng, J. Z., Rostant, D. E., & King, M. R. (2026) · Advanced Healthcare Materials · doi:10.1002/adhm.202600011 · Cited by 1 · see citing works

Reversible electroporation triggers the release of microvesicles affecting viability, migration, and adhesion of melanoma cells

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Single-cell multi-omics reveal epigenomic reprogramming and multicellular ecosystem shaping venous tumor thrombus in hepatocellular carcinoma

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Characterizing pancreatic cancer-associated fibroblast heterogeneity in vascular microphysiological systems

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Tumor Cell Communications as Promising Supramolecular Targets for Cancer Chemotherapy: A Possible Strategy

Алексеенко, И. В., Zhukova, L., Kondratyeva, L. G., Buzdin, A. A., Чернов, И. П., & Sverdlov, E. D. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms251910454 · Cited by 1 · see citing works

Boosting antitumor immunity in breast cancers: Potential of adjuvants, drugs, and nanocarriers

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EHMT2/G9a-Inhibition Reprograms Cancer-Associated Fibroblasts (CAFs) to a More Differentiated, Less Proliferative and Invasive StatePreprint

Wu, N. C., Quevedo, R., Nurse, M., Hezaveh, K., Liu, H., Sun, F., Muffat, J., Sun, Y., Simmons, C. A., McGaha, T. L., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.07.17.549300 · Cited by 1 · see citing works

CHEMOTHERAPY-INDUCED PDL-1 EXPRESSION IN CANCER-ASSOCIATED FIBROBLASTS PROMOTES CHEMORESISTANCE IN NSCLC

Palliyage, G. H. (2023) · doi:10.33915/etd.12138 · Cited by 1 · see citing works

Unveiling the Mechanisms to Bypass KRAS Inhibition: In Vitro Insights into the Influence of Fibroblast-SecretomePreprint

Mendonça, S., Carvalho, P. D., Serra‐Roma, A., Oliveira, P., Ribeiro, A., Carvalho, J., Martins, F., Machado, A. L., Oliveira, M. J., & Velho, S. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.04.19.590324

Targeting Ezrin Can Impede Transformation of Cancer Associated Fibroblast (Caf) to Metastasis Associated Fibroblasts (Maf) in Brca1 Defective Triple Negative Breast CancersPreprint

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ACPA prevents lung fibroblast-to-CAF transformation by reprogramming the tumor microenvironment through NSCLC-derived exosomes

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Additional file 1 of Comprehensive bioinformatic analysis reveals a cancer-associated fibroblast gene signature as a poor prognostic factor and potential therapeutic target in gastric cancer

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Additional file 2 of Musashi-2 in cancer-associated fibroblasts promotes non-small cell lung cancer metastasis through paracrine IL-6-driven epithelial-mesenchymal transition

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Secretome of Stromal Cancer-Associated Fibroblasts (CAFs): Relevance in Cancer

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Mechanism study of cancer-associated fibroblasts and clinical application in breast cancer

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Research progress on cancer-associated fibroblasts in malignant tumors

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Cancer-Associated Fibroblasts: Master Tumor Microenvironment Modifiers

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