Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

Komatsu, Noriko, Okamoto, Kazuo, Sawa, Shinichiro, Nakashima, Tomoki, Oh-hora, Masatsugu, Kodama, Tatsuhiko, Tanaka, Sakae, Bluestone, Jeffrey A +1 more·2014·Nature Medicine

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  20. Arthritis susceptibility and the gut microbiome
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  32. Recruitment and Expansion of Tregs Cells in the Tumor Environment—How to Target Them?
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