Cellular senescence in aging and age-related disease: from mechanisms to therapy

Childs, Bennett G, Durik, Matej, Baker, Darren J, van Deursen, Jan M·2015·Nature Medicine

Cited by (1,011)

Items 701–800 of 1,011

  1. New insights into molecular changes in skeletal muscle aging and disease: Differential alternative splicing and senescence
    Elizaveta M. Solovyeva, Chikwendu Ibebunjo, Stephan Utzinger, John K. Eash, Andrew Dunbar, Ulrike Naumann, Yunyu Zhang, Fabrizio C. Serluca, Sabrina Demirci, Berndt Oberhauser et al. · 2021 · Mechanisms of Ageing and Development
  2. CGRP Regulates the Age-Related Switch Between Osteoblast and Adipocyte Differentiation
    Hang Li, Jian Qu, Haihong Zhu, Jiaojiao Wang, Hao He, Xinyan Xie, Ren Wu, Qiong Lu · 2021 · Frontiers in Cell and Developmental Biology
  3. Mechanisms of skin aging induced by EGFR inhibitors
    Peter Arne Gerber, Bettina Alexandra Buhren, Holger Schrumpf, Peter A. Hevezi, Edwin Bölke, Dennis Sohn, Reiner U. Jänicke, Viswanath Reddy Belum, Caroline Robert, Mario E. Lacouture et al. · 2016 · Supportive Care in Cancer
  4. Advancing biological understanding of cellular senescence with computational multiomics
    Li, Sheng, Agudelo Garcia, Paula A., Aliferis, Constantin, Becich, Michael J., Calyeca, Jazmin, Cosgrove, Benjamin D., Elisseeff, Jennifer, Farzad, Negin, Fertig, Elana J., Glass, Carolyn et al. · 2025 · Nature Genetics
  5. Role of Oxidative Stress in the Senescence Pattern of Auditory Cells in Age-Related Hearing Loss
    Luz del Mar Rivas Chacón, Sofía Martínez-Rodríguez, Raquel Madrid, Joaquin Yanes‐Diaz, Juan Riestra‐Ayora, Ricardo Sanz Fernández, Carolina Sánchez‐Rodríguez · 2021 · Antioxidants
  6. PAI-1: A Major Player in the Vascular Dysfunction in Obstructive Sleep Apnea?
    Mohammad Badran, David Gozal · 2022 · International Journal of Molecular Sciences
  7. Metformin Improves the Senescence of Renal Tubular Epithelial Cells in a High-Glucose State Through E2F1
    Dan Liang, Zhiyang Li, Zhaowei Feng, Zhiping Yuan, Yunli Dai, Xin Wu, Fan Zhang, Yuanyuan Wang, Yüxia Zhou, Lingling Liu et al. · 2022 · Frontiers in Pharmacology
  8. Type 2 Diabetes, Independent of Obesity and Age, Is Characterized by Senescent and Dysfunctional Mature Human Adipose Cells
    Birgit Gustafson, Annika Nerstedt, Rosa Spinelli, Francesco Bèguinot, Ulf Smith · 2022 · Diabetes
  9. A study of the molecular mechanism of quercetin and dasatinib combination as senolytic in alleviating age‐related and kidney diseases
    Khalid Saad Alharbi, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Waleed Hassan Almalki, Imran Ahmed Kazmi, Fahad Ahmed Al-Abbasi, Sami Ibrahim Alzarea, Hafiz Antar Makeen, Mohammed Albratty · 2022 · Journal of Food Biochemistry
  10. DNA damage response(DDR): a link between cellular senescence and human cytomegalovirus
    Xinna Wu, Xuqiang Zhou, Sanying Wang, Genxiang Mao · 2023 · Virology Journal
  11. Emerging concepts and challenges in the development of disease-modifying osteoarthritis drugs – a more refined perspective
    Z. Jenei-Lanzl, Svenja Maurer, Rolf E. Brenner, F. Zaucke, Michael Fuchs, J. Riegger · 2025 · Archives of pharmacal research
  12. Age, gender and UV-exposition related effects on gene expression in in vivo aged short term cultivated human dermal fibroblasts
    Wolfgang Kaisers, Petra Boukamp, Hans‐Jürgen Stark, Holger R. Schwender, Julia Tigges, Jean Krutmann, Heiner Schaal · 2017 · PLoS ONE
  13. IGFBP-3 plays an important role in senescence as an aging marker
    Sugyeong Hong, Moon‐Moo Kim · 2018 · Environmental Toxicology and Pharmacology
  14. Childhood obesity and leucocyte telomere length
    Agaristi Lamprokostopoulou, George Moschonis, Yannis Μanios, Elena Critselis, Nicolas C. Nicolaides, Alketa Stefa, Eleni Koniari, Sarantis Gagos, Evangelia Charmandari · 2019 · European Journal of Clinical Investigation
  15. Regeneration Through in vivo Cell Fate Reprogramming for Neural Repair
    Wenjiao Tai, Xiao‐Ming Xu, Chun‐Li Zhang · 2020 · Frontiers in Cellular Neuroscience
  16. Cell dormancy plasticity: quiescence deepens into senescence through a dimmer switch
    Kotaro Fujimaki, Guang Yao · 2020 · Physiological Genomics
  17. Implication of cellular senescence in the progression of chronic kidney disease and the treatment potencies
    Yao Wang, Ying Wang, Ming Yang, Xingjie Ma · 2021 · Biomedicine & Pharmacotherapy
  18. Ageing, cellular senescence and the impact of diet: an overview
    Ana Isabel Maduro, Carla Luís, Raquel A. Soares · 2021 · Porto Biomedical Journal
  19. Specific Clearance of Senescent Synoviocytes Suppresses the Development of Osteoarthritis based on Aptamer‐Functionalized Targeted Drug Delivery System
    Xiang 'Anthony' Chen, Lei Zhang, Xiaoyan Shao, Wang Gong, Tianshu Shi, Jian Ping Dong, Yong Shi, Siyu Shen, Yi He, Jianghui Qin et al. · 2022 · Advanced Functional Materials
  20. Sirtuin-1 attenuates cadmium-induced renal cell senescence through p53 deacetylation
    Xin Chou, Xiaohu Li, Zhen Min, Fan Ding, Kunpeng Ma, Yue Liang Shen, Daoyuan Sun, Qing Wu · 2022 · Ecotoxicology and Environmental Safety
  21. Sav1 Loss Induces Senescence and Stat3 Activation Coinciding with Tubulointerstitial Fibrosis
    Janet Y. Leung, Harper L. Wilson, Kristin J. Voltzke, Lindsay A. Williams, Hyo Jin Lee, Sara Elizabeth Wobker, William Y. Kim · 2017 · Molecular and Cellular Biology
  22. Genomic instability in the naturally and prematurely aged myocardium
    De Majo, Federica, Martens, Leonie, Hegenbarth, Jana-Charlotte, Rühle, Frank, Hamczyk, Magda R., Nevado, Rosa M., Andrés, Vicente, Hilbold, Erika, Bär, Christian, Thum, Thomas et al. · 2021 · Proceedings of the National Academy of Sciences
  23. Senopathies-Diseases Associated with Cellular Senescence
    Lushchak, Oleh, Schosserer, Markus, Grillari, Johannes · 2023 · Biomolecules
  24. Exercise activates AMPK in mouse and human pancreatic islets to decrease senescence
    Carapeto, Priscila, Iwasaki, Kanako, Hela, Francesko, Kahng, Jiho, Alves-Wagner, Ana B., Middelbeek, Roeland J. W., Hirshman, Michael F., Rutter, Guy A., Goodyear, Laurie J., Aguayo-Mazzucato, Cristina · 2024 · Nature Metabolism
  25. A BDNF-TrkB autocrine loop enhances senescent cell viability
    Anerillas, Carlos, Herman, Allison B., Munk, Rachel, Garrido, Amanda, Lam, Kwan-Wood Gabriel, Payea, Matthew J., Rossi, Martina, Tsitsipatis, Dimitrios, Martindale, Jennifer L., Piao, Yulan et al. · 2022 · Nature Communications
  26. Current Understanding of the Role of Senescent Melanocytes in Skin Ageing
    Bethany K. Hughes, Cleo L. Bishop · 2022 · Biomedicines
  27. An untapped window of opportunity for glioma: targeting therapy-induced senescence prior to recurrence
    Cécile Riviere-Cazaux, Lucas P. Carlstrom, Bryan J. Neth, Ian Olson, Karishma R. Rajani, Masum Rahman, Samar Ikram, Moustafa A. Mansour, Bipasha Mukherjee, Arthur E. Warrington et al. · 2023 · npj Precision Oncology
  28. Senotherapy: growing old and staying young?
    Roland Schmitt · 2017 · Pflügers Archiv - European Journal of Physiology
  29. Microenvironment-Cell Nucleus Relationship in the Context of Oxidative Stress
    Shirisha Chittiboyina, Yunfeng Bai, Sophie A. Lelièvre · 2018 · Frontiers in Cell and Developmental Biology
  30. Hydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo
    Wenbo Zhang, Chao Hui Huang, Aijun Sun, Liang Qiao, Xi Zhang, Junlong Huang, Xuejun Sun, Xiangqun Yang, Shanquan Sun · 2018 · Biomedicine & Pharmacotherapy
  31. Endothelial Extracellular Vesicles Produced by Senescent Cells: Pathophysiological Role in the Cardiovascular Disease Associated with all Types of Diabetes Mellitus
    Julia Carracedo, Matilde Alique, Rafael Ramírez-Carracedo, Guillermo Bodega, Rafael Ramı́rez · 2018 · Current Vascular Pharmacology
  32. Deciphering the Molecular Mechanism of Spontaneous Senescence in Primary Epithelial Ovarian Cancer Cells
    Martyna Pakuła, E. Maly, P. Uruski, A. Witucka, M. Bogucka, Natalia Jaroszewska, N. Makowska, A. Niklas, R. Moszyński, S. Sajdak et al. · 2020 · Cancers
  33. Recent update on discovery and development of Hsp90 inhibitors as senolytic agents
    Sayan Dutta Gupta, Cheol Ho Pan · 2020 · International Journal of Biological Macromolecules
  34. FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer
    Norihiko Sasaki, Fujiya Gomi, Hisashi Yoshimura, Masami Yamamoto, Yoko Matsuda, Masaki Michishita, Hitoshi Hatakeyama, Yoichi Kawano, Masashi Toyoda, Murray Korc et al. · 2020 · Cancers
  35. TFEB protein expression is reduced in aged brains and its overexpression mitigates senescence-associated biomarkers and memory deficits in mice
    Hongjie Wang, Mohan Kumar Muthu Karuppan, Dinesh Devadoss, Madhavan Nair, Hitendra Singh Chand, Madepalli Krishnappa Lakshmana · 2021 · Neurobiology of Aging
  36. p27, The Cell Cycle and Alzheimer´s Disease
    Ana García‐Osta, Jinya Dong, María Jesús Moreno-Aliaga, María Javier Ramírez · 2022 · International Journal of Molecular Sciences
  37. Induced Pluripotent Stem Cell-Based Drug Screening by Use of Artificial Intelligence
    Dai Kusumoto, Shinsuke Yuasa, Keiichi Fukuda · 2022 · Pharmaceuticals
  38. Electrophilic Compounds in the Human Diet and Their Role in the Induction of the Transcription Factor NRF2
    Celia María Curieses Andrés, José Manuel Pérez de la Lastra, Elena Bustamante Munguira, Celia Andrés, Francisco J. Plou, Eduardo Pérez Lebeña · 2024 · International Journal of Molecular Sciences
  39. Accelerated Aging Induced by an Unhealthy High-Fat Diet: Initial Evidence for the Role of Nrf2 Deficiency and Impaired Stress Resilience in Cellular Senescence
    Priya Balasubramanian, Tamás Kiss, Rafał Gulej, Adam Nyul Toth, Stefano Tarantini, Andriy Yabluchanskiy, Zoltan I. Ungvari, Anna Csiszár · 2024 · Nutrients
  40. Epithelial–mesenchymal transition to mitigate age-related progression in lung cancer
    Riya Thapa, Saurabh Gupta, Gaurav Gupta, Asif Ahmad Bhat, Smriti, Smriti, Haider Ali, Sachin Kumar Singh, Kamal Dua, Manoj Kumar Kashyap · 2024 · Ageing Research Reviews
  41. In vivo reprogramming for tissue regeneration and organismal rejuvenation
    Jumpei Taguchi, Yasuhiro Yamada · 2017 · Current Opinion in Genetics & Development
  42. Protein sequestration at the nuclear periphery as a potential regulatory mechanism in premature aging
    Leonid Serebryannyy, Tom Misteli · 2017 · The Journal of Cell Biology
  43. Cellular Senescence in the Treatment of Ovarian Cancer
    Zehua Wang, Haiou Liu, Congjian Xu · 2018 · International Journal of Gynecological Cancer
  44. The role of STAT3/mTOR-regulated autophagy in angiotensin II-induced senescence of human glomerular mesangial cells
    Shuang Yang, Dan Sun, Lining Wang, Xiuying Wang, Mai Shi, Xue Jiang, Xinran Gao · 2018 · Cellular Signalling
  45. Administration of hydrogen-rich water prevents vascular aging of the aorta in LDL receptor-deficient mice
    Masumi Iketani, Kanako Sekimoto, Tsutomu Igarashi, Mayumi M. Takahashi, Masaki Komatsu, Iwao Sakane, Hiroshi Takahashi, Hideo Kawaguchi, Ritsuko Ohtani‐Kaneko, Ikuroh Ohsawa · 2018 · Scientific Reports
  46. Manipulation of molecular pathways and senescence hallmarks by natural compounds in fibroblast cells
    Saeideh Momtaz, Maryam Baeeri, Mahban Rahimifard, Hamed Haghi‐Aminjan, Shokoufeh Hassani, Mohammad Reza Abdollahi · 2018 · Journal of Cellular Biochemistry
  47. Tackling Aging by Using miRNA as a Target and a Tool
    Wing‐Fu Lai, Marie Lin, Wing‐Tak Wong · 2019 · Trends in Molecular Medicine
  48. Intermedin1-53 attenuates aging-associated vascular calcification in rats by upregulating sirtuin 1
    Yao Chen, Linshuang Zhang, Jin-Ling Ren, Ya-Rong Zhang, Ning Wu, Mo-Zhi Jia, Yan-Rong Yu, Zhongping Ning, Chaoshu Tang, Yongfen Qi · 2020 · Aging
  49. Treating age-related multimorbidity: the drug discovery challenge
    Christos Ermogenous, Charlotte Green, Thomas Jackson, Michael A. J. Ferguson, Janet M. Lord · 2020 · Drug Discovery Today
  50. Effects of cellular senescence on metabolic pathways in non-immune and immune cells
    Daniela Frasca, Yara Bou Saada, Denisse Garcia, Bertrand Friguet · 2020 · Mechanisms of Ageing and Development
  51. Neutralization of oxidized phospholipids attenuates age‐associated bone loss in mice
    Michela Palmieri, Maria Almeida, Intawat Nookaew, Horacio Gómez-Acevedo, Teenamol E. Joseph, Xuchu Que, Sotirios Tsimikas, Xiaoli Sun, Stavros C. Manolagas, Joseph Lee Witztum et al. · 2021 · Aging Cell
  52. Spatially Confined Intervention of Cellular Senescence by a Lysosomal Metabolism Targeting Molecular Prodrug for Broad‐Spectrum Senotherapy
    Yinghao Xia, Jili Li, Linlin Wang, Xiyuan Luo, Yuqi Xie, Yanlan Liu · 2022 · Angewandte Chemie International Edition
  53. A Tandemly Activated Fluorescence Probe for Detecting Senescent Cells with Improved Selectivity by Targeting a Biomarker Combination
    Lei Zhou, Xuan Kai Zhang, Ying Dong, Yuan Jiang Pan, Jia Xuan Li, Yi Zang, Xin Li · 2022 · ACS Sensors
  54. Celastrol alleviates angiotensin II-mediated vascular smooth muscle cell senescence via induction of autophagy
    Xian-Jie Xu, Weibo Zhao, Shibin Feng, Cheng Sun, Qiang Chen, Bing Ni, Houyuan Hu · 2017 · Molecular Medicine Reports
  55. Cerebral Microvascular Senescence and Inflammation in Diabetes
    Ashley Phoenix, Raghavendar Chandran, Adviye Ergul · 2022 · Frontiers in Physiology
  56. Aberrant induction of p19Arf-mediated cellular senescence contributes to neurodevelopmental defects
    Muriel Rhinn, Irene Zapata-Bodalo, Annabelle Klein, Jean‐Luc Plassat, Tania Knauer-Meyer, William M. Keyes · 2022 · PLoS Biology
  57. The Bcl-2/Bcl-xL Inhibitor ABT-263 Attenuates Retinal Degeneration by Selectively Inducing Apoptosis in Senescent Retinal Pigment Epithelial Cells
    Wonseon Ryu, Chul-Woo Park, Junghoon Kim, Hyungwoo Lee, Hyewon Chung · 2023 · Molecules and Cells
  58. The Potential of Polyphenols in Modulating the Cellular Senescence Process: Implications and Mechanism of Action
    Larissa Della Vedova, Giovanna Baron, Paolo Morazzoni, Giancarlo Aldini, Francesca Gado · 2025 · Pharmaceuticals
  59. Senolytic treatment for low back pain
    Matthew Mannarino, Hosni Cherif, Saber Ghazizadeh Darband, Oliver Wu Martinez, Kai Sheng, Elsa Cousineau, Seunghwan Lee, Magali Millecamps, Chan Gao, Alice Gilbert et al. · 2025 · Science Advances
  60. Cellular senescence in chronic obstructive pulmonary disease: Molecular mechanisms and therapeutic interventions
    Sapana Subedi, Mounika Guntipally, Newton Suwal, Rajan Thapa, Saroj Bashyal, Nisha Panth, Gaurav Gupta, Ronan J. MacLoughlin, Brian Gregory George Oliver, Kamal Dua et al. · 2025 · Ageing Research Reviews
  61. Radical scavenging activity of sulfated Bupleurum chinense polysaccharides and their effects against oxidative stress-induced senescence
    Haibin Tong, Xiaoli Zheng, Jianxi Song, Jian Liu, Ting Ren, Xu Zhang, Luqi Huang, Mingjiang Wu · 2018 · Carbohydrate Polymers
  62. DNA damage response induced by Etoposide promotes steroidogenesis via GADD45A in cultured adrenal cells
    Mimi Tamamori‐Adachi, Akane Koga, Takao Susa, Hiroko Fujii, Masao Tsuchiya, Hiroko Okinaga, Harumi Hisaki, Masayoshi Iizuka, Shigetaka Kitajima, Tomoki Okazaki · 2018 · Scientific Reports
  63. The Endocannabinoid System May Modulate Sleep Disorders in Aging
    Eric Murillo‐Rodríguez, Henning Budde, André Barciela Veras, Nuno Rocha, Diogo Telles‐Correia, Diogo Monteiro, Luí­s Cid, Tetsuya Yamamoto, Sergio Eduardo de Carvalho Machado, Pablo Torterolo · 2019 · Current Neuropharmacology
  64. RETRACTED: Cannabinoids as anti-ROS in aged pancreatic islet cells
    Maryam Baeeri, Mahban Rahimifard, Seyed Mojtaba Daghighi, Fazlullah Khan, Seyed Alireza Salami, Shermineh Moeini‐Nodeh, Hamed Haghi‐Aminjan, Zahra Bayrami, Farhad Rezaee, Mohammad Reza Abdollahi · 2020 · Life Sciences · Retracted
  65. The role of telomeres and telomerase in the senescence of postmitotic cells
    Anna Pańczyszyn, Ewa Boniewska‐Bernacka, Anna Goc · 2020 · DNA repair
  66. Immune Regulation of the cGAS-STING Signaling Pathway in the Tumor Microenvironment and Its Clinical Application
    Feifei Pu, Fengxia Chen, Jianxiang Liu, Zhicai Zhang, Zengwu Shao · 2021 · OncoTargets and Therapy
  67. Fluorescent nanocarriers targeting VCAM-1 for early detection of senescent endothelial cells
    Eugenia Belcastro, Asad Ur Rehman, Lamia Remila, Sin‐Hee Park, David Gong, Nicolas Anton, Cyril Auger, Olivier Lefèbvre, Jacky G. Goetz, Mayeul Collot et al. · 2021 · Nanomedicine Nanotechnology Biology and Medicine
  68. Loss of legumain induces premature senescence and mediates aging‐related renal fibrosis
    Dekun Wang, Lichun Kang, Chuan’ai Chen, Jiasen Guo, Lingfang Du, Donghui Zhou, Gang Li, Yuying Zhang, Xue Mi, Mianzhi Zhang et al. · 2022 · Aging Cell
  69. Miscarriage syndrome: Linking early pregnancy loss to obstetric and age-related disorders
    Pietro E. Bortoletto, Emma S. Lucas, Pedro Melo, Ioannis D. Gallos, Adam Devall, Tom Bourne, Siobhan M. Quenby, Phillip R. Bennett, Arri Coomarasamy, Jan Joris Brosens · 2022 · EBioMedicine
  70. Identification of new genes associated to senescent and tumorigenic phenotypes in mesenchymal stem cells
    Joana Cristina Medeiros Tavares Marques, Déborah Afonso Cornélio, Vivian Nogueira Silbiger, André Ducati Luchessi, Sandro de Souza, Sílvia Regina Batistuzzo de Medeiros · 2017 · Scientific Reports
  71. Suppression of TREX1 deficiency-induced cellular senescence and interferonopathies by inhibition of DNA damage response
    Hekang Du, Nanyang Xiao, Sitong Zhang, Xueyuan Zhou, Yangfan Zhang, Zengzeng Lu, Yuqian Fu, Miaohui Huang, Shan Xu, Qi Chen · 2023 · iScience
  72. Branched‐Chain Amino Acid Accumulation Fuels the Senescence‐Associated Secretory Phenotype
    Yaosi Liang, Christopher C. Pan, Tao Yin, Lu Wang, Xia Gao, Ergang Wang, Holly Quang, De Huang, Lianmei Tan, Kun Xiang et al. · 2023 · Advanced Science
  73. Therapeutic effects of resveratrol on epigenetic mechanisms in age‐related diseases: A comprehensive review
    Sale Zhang, Farzam Kiarasi · 2024 · Phytotherapy Research
  74. Molecular hallmarks of ageing in amyotrophic lateral sclerosis
    Cyril Jones Jagaraj, Sina Shadfar, Sara Assar Kashani, Sayanthooran Saravanabavan, Fabiha Farzana, Julie D. Atkin · 2024 · Cellular and Molecular Life Sciences
  75. Understanding the intricacies of cellular senescence in atherosclerosis: Mechanisms and therapeutic implications
    Ilyas Ali, Hongliang Zhang, Syed Aqib Ali Zaidi, Guangqian Zhou · 2024 · Ageing Research Reviews
  76. Senolytic Therapy Enabled by Senescent Cell‐Sensitive Biomimetic Melanin Nano‐Senolytics
    Hairui Zhang, Xiaoling Xu, Xin Shou, Wucan Liao, Chengkang Jin, Changjiang Chen, Chen Yu Zhang, Wenhua Gao, Junfeng Zhang, Weihong Ge et al. · 2024 · Advanced Healthcare Materials
  77. Multifunctional scaffolds for bone repair following age-related biological decline: Promising prospects for smart biomaterial-driven technologies
    Jonathan D. Schwartzman, Max McCall, Yasmine S. Ghattas, Abinaya Sindu Pugazhendhi, Fei Wei, Christopher Ngo, Jonathan Ruiz, Sudipta Seal, Melanie Jean Coathup · 2024 · Biomaterials
  78. Developing transcriptomic signatures as a biomarker of cellular senescence
    Shamsed Mahmud, Louise E. Pitcher, Elijah Torbenson, Paul D. Robbins, Lei Zhang, Xiao Dong · 2024 · Ageing Research Reviews
  79. GATD3A-deficiency-induced mitochondrial dysfunction facilitates senescence of fibroblast-like synoviocytes and osteoarthritis progression
    Kai Shen, Hao Zhou, Qiang Zuo, Yue Gu, Jiangqi Cheng, Kai Yan, Huiwen Zhang, Huanghe Song, Wen-Wei Liang, Jinchun Zhou et al. · 2024 · Nature Communications
  80. Fibroblasts potentiate melanoma cells in vitro invasiveness induced by UV-irradiated keratinocytes
    Njainday Pulo Jobe, Veronika Bandúrová, Alžběta Fíková, Daniel Rösel, Barbora Dvořánková, Ondřej Kodet, Hynek Strnad, Michal Kolář, Aleksi Šedo, Karel Smetana et al. · 2018 · Histochemistry and Cell Biology
  81. Regulatory RNA binding proteins contribute to the transcriptome-wide splicing alterations in human cellular senescence
    Qiongye Dong, Lei Wei, Michael Q. Zhang, Xiaowo Wang · 2018 · Aging
  82. Rat Glioma Cell-Based Functional Characterization of Anti-Stress and Protein Deaggregation Activities in the Marine Carotenoids, Astaxanthin and Fucoxanthin
    Sajal Afzal, Sukant Garg, Yoshiyuki Ishida, Keiji Terao, Sunil C. Kaul, Renu Wadhwa · 2019 · Marine Drugs
  83. Data-Driven Analysis of Age, Sex, and Tissue Effects on Gene Expression Variability in Alzheimer's Disease
    Brooks, Lavida R. K., Mias, George I. · 2019 · Frontiers in Neuroscience
  84. HNRNPA1-mediated 3′ UTR length changes of HN1 contributes to cancer- and senescence-associated phenotypes
    Qi Jia, Hongbo Nie, Peng Yu, Baiyun Xie, Chenji Wang, Fu Yang, Gang Wei, Ting Ni · 2019 · Aging
  85. (Pro)renin receptor accelerates development of sarcopenia via activation of Wnt/YAP signaling axis
    Naohiro Yoshida, Jin Endo, Kenichiro Kinouchi, Hiroki Kitakata, Hidenori Moriyama, Masaharu Kataoka, Tsunehisa Yamamoto, Kohsuke Shirakawa, Satoshi Morimoto, Akira Nishiyama et al. · 2019 · Aging Cell
  86. Artemether Attenuates the Progression of Non-small Cell Lung Cancer by Inducing Apoptosis, Cell Cycle Arrest and Promoting Cellular Senescence
    Jian Chen, Xiaofei Huang, Cheng Tao, Ting Xiao, Xinping Li, Qiang Zeng, Min Ma, Zhengzhi Wu · 2019 · Biological and Pharmaceutical Bulletin
  87. Low Intensity Vibrations Augment Mesenchymal Stem Cell Proliferation and Differentiation Capacity during in vitro Expansion
    Guniz Bas, Stacie Loisate, Stephanie Fern Hudon, Kali Woods, Eric J. Hayden, Xinzhu Pu, Richard S. Beard, Julia Thom Oxford, Gunes Uzer · 2020 · Scientific Reports
  88. Urolithin A Protects Chondrocytes From Mechanical Overloading-Induced Injuries
    Yuchen He, Lauren Yocum, Peter Geoffrey Alexander, Michael J. Jurczak, Hang Lin · 2021 · Frontiers in Pharmacology
  89. Highly concentrated trehalose induces prohealing senescence-like state in fibroblasts via CDKN1A/p21
    Jun Muto, Shinji Fukuda, Kenji Watanabe, Xiuju Dai, Teruko Tsuda, Takeshi Kiyoi, Kenji Kameda, Ryosuke Kawakami, Hideki Mori, Ken Shiraishi et al. · 2023 · Communications Biology
  90. Mesenchymal stromal cell senescence in haematological malignancies
    Natalya Plakhova, Vasilios Panagopoulos, Kate Vandyke, Andrew C.W. Zannettino, Krzysztof Marek Mrozik · 2023 · Cancer and Metastasis Reviews
  91. Extracellular Vesicles as “Very Important Particles” (VIPs) in Aging
    Cristina Mas‐Bargues, Matilde Alique · 2023 · International Journal of Molecular Sciences
  92. Regulation of stem cell aging by SIRT1 – Linking metabolic signaling to epigenetic modifications
    Yu An, Weiwei Dang · 2017 · Molecular and Cellular Endocrinology
  93. Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer
    Ryosuke Tanino, Yukari Tsubata, Nanae Harashima, Mamoru Harada, Takeshi Isobe · 2018 · Oncotarget
  94. Novel role of PKR in palmitate-induced Sirt1 inactivation and endothelial cell senescence
    Yapei Li, Zhouyangfan Peng, Chunle Wang, Le Li, Yiping Leng, Ruifang Chen, Hong Yuan, Shenghua Zhou, Zhen Zhang, Alex F. Chen · 2018 · American Journal of Physiology-Heart and Circulatory Physiology
  95. Endothelial Cell Aging: How miRNAs Contribute?
    Munekazu Yamakuchi, Teruto Hashiguchi · 2018 · Journal of Clinical Medicine
  96. Rejuvenating effects of young extracellular vesicles in aged rats and in cellular models of human senescence
    Lilian Grigorian Shamagian, Russell George Rogers, Kristin M. Luther, David Angert, Antonio K. Echavez, Weixin Liu, Ryan Middleton, Travis J. Antes, Jackelyn Valle, Mario Fourier et al. · 2023 · Scientific Reports
  97. Endothelial Senescence: From Macro- to Micro-Vasculature and Its Implications on Cardiovascular Health
    Peichun Wang, Daniels Konja, Sandeep Singh, Beijia Zhang, Yu Wang · 2024 · International Journal of Molecular Sciences
  98. CD4+CD57+ senescent T cells as promoters of systemic lupus erythematosus pathogenesis and the therapeutic potential of senolytic BCL‐2 inhibitor
    Jiao Jiang, Ming Yang, Huan Zhu, Di Long, Zhenghao He, Juan Liu, Liting He, Yixin Tan, Arne N. Akbar, Venkat R Reddy et al. · 2024 · European Journal of Immunology
  99. A nutrigeroscience approach: Dietary macronutrients and cellular senescence
    Mariah F. Calubag, Paul D. Robbins, Dudley W. Lamming · 2024 · Cell Metabolism
  100. MicroRNA-126: From biology to therapeutics
    Bei Guo, Jia Gu, Tongtian Zhuang, Jingbin Zhang, Chunyang Fan, Yiyao Li, Mengdi Zhao, Ruoran Chen, Rui Wang, Yuan Kong et al. · 2025 · Biomedicine & Pharmacotherapy