A bone marrow factor contributes to kidney disease
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Bone-marrow-derived immune cells are activated by the gut microbiota, leading to low-grade inflammation that affects the brain, ANS and the kidney via the circulation.
“Bone-marrow-derived immune cells are activated by the gut microbiota, leading to low-grade inflammation that affects the brain, ANS and the kidney via the circulation13–15.”
From The gut microbiota and the brain–gut–kidney axis in hypertension and chronic kidney disease (2018) · cites this paper as [14]
Cites
Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis
Wei, C., Hindi, S. E., Li, J., Fornoni, A., Goes, N. B., Sageshima, J., Maiguel, D. A., Karumanchi, S. A., Yap, H., Saleem, M. A., et al. (2011) · Nature Medicine · doi:10.1038/nm.2411 · Cited by 840 · see citing works
Modification of kidney barrier function by the urokinase receptor
Wei, C., Möller, C., Altintas, M. M., Li, J., Schwarz, K., Zacchigna, S., Xie, L., Henger, A., Schmid, H., Rastaldi, M. P., et al. (2007) · Nature Medicine · doi:10.1038/nm1696 · Cited by 524 · see citing works
Soluble Urokinase Receptor and Chronic Kidney Disease
Hayek, S. S., Sever, S., Ko, Y.-A., Trachtman, H., Awad, M., Wadhwani, S., Altintas, M. M., Wei, C., Hotton, A., French, A., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1506362 · Cited by 388 · see citing works
Eugen‐Olsen, J., Andersen, O., Linneberg, A. R., Ladelund, S., Hansen, T. W., Langkilde, A., Petersen, J., Pielak, T., Møller, L. N., Jeppesen, J., et al. (2010) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2010.02252.x · Cited by 383 · see citing works
Hahm, E., Wei, C., Fernandez, I., Li, J., Tardi, N. J., Tracy, M. J., Wadhwani, S., Cao, Y., Peev, V., Zloza, A., et al. (2016) · Nature Medicine · doi:10.1038/nm.4242 · Cited by 153 · see citing works
A reassessment of soluble urokinase-type plasminogen activator receptor in glomerular disease
Spinale, J. M., Mariani, L. H., Kapoor, S. C., Zhang, J., Weyant, R., Song, P. X. ‐., Wong, H. N., Troost, J. P., Gadegbeku, C. A., Gipson, D. S., et al. (2014) · Kidney International · doi:10.1038/ki.2014.346 · Cited by 121 · see citing works
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The gut microbiota and the brain–gut–kidney axis in hypertension and chronic kidney disease
Yang, T., Richards, E. M., Pepine, C. J., & Raizada, M. K. (2018) · Nature Reviews Nephrology · doi:10.1038/s41581-018-0018-2 · Cited by 753 · see citing works
Kiuchi, M. G., Ho, J. K., Nolde, J. M., Gavidia, L. M. L., Carnagarin, R., Matthews, V. B., & Schlaich, M. P. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2019.01546 · Cited by 36 · see citing works
Guan, Y., Chen, K., Quan, D., Kang, L., Yang, D., Wu, H., Yan, M., Wu, S., Lv, L., & Zhang, G. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.575294 · Cited by 36 · see citing works
suPAR as a marker of infection in acute kidney injury – a prospective observational study
Hall, A., Crichton, S. L., Varrier, M., Bear, D. E., & Ostermann, M. (2018) · BMC Nephrology · doi:10.1186/s12882-018-0990-6 · Cited by 10 · see citing works
Yang, A., Chidiac, R., Russo, E. E., Steenland, H. W., Pauli, Q., Bonin, R. P., Blazer, L. L., Adams, J., Sidhu, S. S., Goeva, A., et al. (2024) · Development · doi:10.1242/dev.202545 · Cited by 8 · see citing works
The Perspective of Vitamin D on suPAR-Related AKI in COVID-19
Liao, T.-H., Wu, H.-C., Liao, M.-T., Hu, W., Tsai, K., Lin, C., & Lu, K. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231810725 · Cited by 8 · see citing works
Novel Approaches to Immunotherapy in Triple Negative Breast Cancer
Tabarestani, S., Akbari, M. E., & Namaki, S. (2018) · International Journal of Cancer Management · doi:10.5812/ijcm.87024 · Cited by 2 · see citing works
- Authors
- Shankland, S. J., & Jefferson, J. A.
- Affiliations
- University of Washington (US)
- Corresponding author
- Shankland, Stuart J
- Venue
- Nature Medicine
- Published
- 2017-01
- Volume
- 23
- Issue
- 1
- Pages
- 13-14
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W2569691699
- Cited by
- 7
- References
- 6
- Citations by year
- 2024: 1 · 2022: 1 · 2021: 1 · 2020: 1 · 2018: 3
- FWCI
- 0.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Inflammation biomarkers and pathways
- Health Sciences › Medicine › Nephrology › Chronic Kidney Disease and Diabetes
- Health Sciences › Medicine › Nephrology › Dialysis and Renal Disease Management
- Keywords
- soluble urokinase plasminogen activator receptor, suPAR, immature myeloid cells, bone marrow, kidney disease, inflammation, biomarkers, myeloid-derived cells
- MeSH terms
- Bone Marrow, Bone Marrow Cells, Humans, Kidney, Kidney Diseases, Bone Marrow Transplantation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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