Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas

Piunti, Andrea, Hashizume, Rintaro, Morgan, Marc A, Bartom, Elizabeth T, Horbinski, Craig M, Marshall, Stacy A, Rendleman, Emily J, Ma, Quanhong +9 more·2017·Nature Medicine

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  13. Diffuse Midline Glioma – Diffuse Intrinsic Pontine Glioma
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  14. Super elongation complex as a targetable dependency in diffuse midline glioma
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    Lerco Elisa · 2014 · Publications Docs-en-stock.com
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