Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas

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Items 401–458 of 458

  1. Supplementary Data S1 from Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways
    Sriram Venneti, Abed Rahman Kawakibi, Sunjong Ji et al. · 2023
  2. Supplementary Data S2 from Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways
    Sriram Venneti, Abed Rahman Kawakibi, Sunjong Ji et al. · 2023
  3. Supplementary Data S2 from Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways
    Sriram Venneti, Abed Rahman Kawakibi, Sunjong Ji et al. · 2023
  4. Supplementary Data S1 from Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways
    Sriram Venneti, Abed Rahman Kawakibi, Sunjong Ji et al. · 2023
  5. Reviewer #1 (Public Review): BMP2 and BMP7 cooperate with H3.3K27M to promote quiescence and invasiveness in pediatric diffuse midline gliomas
    Paul Huchedé, Swann Meyer, Clément Berthelot et al. · 2023
  6. Reviewer #2 (Public Review): BMP2 and BMP7 cooperate with H3.3K27M to promote quiescence and invasiveness in pediatric diffuse midline gliomas
    Paul Huchedé, Swann Meyer, Clément Berthelot et al. · 2023
  7. BMP2 and BMP7 cooperate with H3.3K27M to promote quiescence and invasiveness in pediatric diffuse midline gliomas
    Paul Huchedé, Swann Meyer, Clément Berthelot et al. · 2023 · eLife
  8. eLife Assessment: BMP2 and BMP7 cooperate with H3.3K27M to promote quiescence and invasiveness in pediatric diffuse midline gliomas
    Lynne-Marie M Postovit · 2023
  9. Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas
    Danielle Algranati, Roni Oren, Bareket Dassa, Liat Fellus-Alyagor, Alexander N. Plotnikov, Haim Michael Barr, Alon Harmelin, Nir London, Guy Ron, Noa Furth et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  10. Additional file 1 of Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma
    Guisheng Zhao, Patrick A. Newbury, Yukitomo Ishi, Eugene Chekalin, Billy Zeng, Benjamin Scott Glicksberg, Anita Wen, Shreya Paithankar, Takahiro Sasaki, Amreena Suri et al. · 2022 · Figshare
  11. Additional file 3 of Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma
    Guisheng Zhao, Patrick A. Newbury, Yukitomo Ishi, Eugene Chekalin, Billy Zeng, Benjamin Scott Glicksberg, Anita Wen, Shreya Paithankar, Takahiro Sasaki, Amreena Suri et al. · 2022 · Figshare
  12. Additional file 8 of Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma
    Guisheng Zhao, Patrick A. Newbury, Yukitomo Ishi, Eugene Chekalin, Billy Zeng, Benjamin Scott Glicksberg, Anita Wen, Shreya Paithankar, Takahiro Sasaki, Amreena Suri et al. · 2022 · Figshare
  13. Additional file 7 of Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma
    Guisheng Zhao, Patrick A. Newbury, Yukitomo Ishi, Eugene Chekalin, Billy Zeng, Benjamin Scott Glicksberg, Anita Wen, Shreya Paithankar, Takahiro Sasaki, Amreena Suri et al. · 2022 · Figshare
  14. Additional file 2 of Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma
    Guisheng Zhao, Patrick A. Newbury, Yukitomo Ishi, Eugene Chekalin, Billy Zeng, Benjamin Scott Glicksberg, Anita Wen, Shreya Paithankar, Takahiro Sasaki, Amreena Suri et al. · 2022 · Figshare
  15. Additional file 2 of Defining super-enhancers by highly ranked histone H4 multi-acetylation levels identifies transcription factors associated with glioblastoma stem-like properties
    Nando Dulal Das, Jen-Chien Chang, Chung-Chau Hon, S. Thomas Kelly, Shinsuke Ito, Marina Lizio, Bogumił Kaczkowski, Hisami Watanabe, Keisuke Katsushima, Atsushi Natsume et al. · 2023 · Figshare
  16. Additional file 6 of Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma
    Guisheng Zhao, Patrick A. Newbury, Yukitomo Ishi, Eugene Chekalin, Billy Zeng, Benjamin Scott Glicksberg, Anita Wen, Shreya Paithankar, Takahiro Sasaki, Amreena Suri et al. · 2022 · Figshare
  17. Additional file 5 of Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma
    Guisheng Zhao, Patrick A. Newbury, Yukitomo Ishi, Eugene Chekalin, Billy Zeng, Benjamin Scott Glicksberg, Anita Wen, Shreya Paithankar, Takahiro Sasaki, Amreena Suri et al. · 2022 · Figshare
  18. Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas
    Danielle Algranati, Roni Oren, Bareket Dassa, Liat Fellus-Alyagor, Alexander N. Plotnikov, Haim Michael Barr, Alon Harmelin, Nir London, Guy Ron, Noa Furth et al. · 2024 · eLife
  19. Author Response: BMP2 and BMP7 cooperate with H3.3K27M to promote quiescence and invasiveness in pediatric diffuse midline gliomas
    Paul Huchedé, Swann Meyer, Clément Berthelot et al. · 2023
  20. Chromatin remodeling with combined FACT and BET inhibition disrupts oncogenic transcription in Diffuse Midline Glioma
    Holly Holliday, Aaminah Khan, Anahid Ehteda, Hieu Trung Nguyen, Samuel E. Ross, Nisitha Jayatilleke, Anjana Gopalakrishnan, Eyden Wang, Yolanda Colino‐Sanguino, Daisy Kavanagh et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  21. Reviewer #2 (Public Review): Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas
    Danielle Algranati, Roni Oren, Bareket Dassa et al. · 2024 · eLife
  22. Author response: Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas
    Danielle Algranati, Roni Oren, Bareket Dassa, Liat Fellus-Alyagor, Alexander N. Plotnikov, Haim Michael Barr, Alon Harmelin, Nir London, Guy Ron, Noa Furth et al. · 2024 · eLife
  23. eLife Assessment: Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas
    Yamini Dalal · 2024 · eLife
  24. Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas
    Danielle Algranati, Roni Oren, Bareket Dassa, Liat Fellus-Alyagor, Alexander N. Plotnikov, Haim Michael Barr, Alon Harmelin, Nir London, Guy Ron, Noa Furth et al. · 2024 · eLife
  25. BMP2 and BMP7 cooperate with H3.3K27M to promote quiescence and invasiveness in pediatric diffuse midline gliomas
    Paul Huchedé, Swann Meyer, Clément Berthelot et al. · 2024 · eLife
  26. eLife Assessment: BMP2 and BMP7 cooperate with H3.3K27M to promote quiescence and invasiveness in pediatric diffuse midline gliomas
    Lynne-Marie M Postovit · 2024
  27. Reviewer #1 (Public Review): BMP2 and BMP7 cooperate with H3.3K27M to promote quiescence and invasiveness in pediatric diffuse midline gliomas
    Paul Huchedé, Swann Meyer, Clément Berthelot et al. · 2024
  28. Author response: BMP2 and BMP7 cooperate with H3.3K27M to promote quiescence and invasiveness in pediatric diffuse midline gliomas
    Paul Huchedé, Swann Meyer, Clément Berthelot et al. · 2024
  29. A pontine-specific axonal niche supports de novo gliomagenesis
    Zhigang Xie, Adrija Pathak, Vytas A. Bankaitis · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  30. The Impact of Epigenetic Methylation on Gliomagenesis: An Understanding and Therapeutic Approaches
    Kholoud K. Arafa, Zahra Hanafy, Mohamed Medhat, Reem K. Arafa · 2024 · Interdisciplinary cancer research
  31. Pediatric High Grade Glioma
    Craig Alexander Erker, Magimairajan Vanan, Vivek Mehta, David D. Eisenstat · 2024 · Springer eBooks
  32. The role of chemotherapy in patients with H3K27M-mutant diffuse midline gliomas: a SEER-based propensity scored matching study
    Jin Zhang, Shanshan Wang, Sichen Wang · 2024 · Research Square
  33. Pediatric-type diffuse high-grade gliomas
    Michelle Monje, Steve E. Braunstein, Mitchel Stuart Berger, Hannes S. Vogel · 2025 · Oxford University Press eBooks
  34. PALB2 deficiency may sensitize H3K27M-mutant pediatric HGG cells to BMN673/talazoparib
    Xiaowen Guan, Xinke Xu, Xiaolan Mo, Houliang Deng · 2025 · Frontiers in Oncology
  35. Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes
    Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon · 2025 · Molecular Oncology
  36. Priming Anti-Tumour Immunity in Paediatric High-Grade Brain Tumours Through Low-Dose Immunogenic Radiotherapy: A Preclinical Paradigm for Enhancing Survival and Preserving Neurodevelopment Literature Analysis
    W. D. Chambers · 2025 · SSRN Electronic Journal
  37. Multiplexed measurements of protein-protein interactions and protein abundance across cellular conditions using Prod&PQ-seq
    Tianyao Xu, Jingyao Wang, Yoonju Shin, Yuwei Cao, Lingzhi Zhang, Eduardo Modolo, Tamar Dishon, Jeremy Fisher, Matthew Norton, Christopher J. Fry et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  38. Direct Readout of Multivalent Chromatin Reader-Nucleosome Interactions by Nucleosome Mass Spectrometry
    Alexander S. Lee, Nickolas P. Fisher, M. Marunde, Pei Su, Laiba F. Khan, Ryan J. Ezell, Zachary B. Gillespie, Bria Graham, Hailey F. Taylor, Ugochi C. Onuoha et al. · 2026 · ACS Central Science
  39. A new hope: Clinical advances in targeted therapies for pediatric diffuse midline glioma
    Joshua Zhu, Maria Tsoli, Jean Borges Bertoldo, Sabine Mueller, David Simon Ziegler · 2025 · Neuro-Oncology Advances
  40. Outcomes of H3K27M-altered diffuse midline glioma adult Chinese patients and real-world experience with German-sourced ONC201 targeted therapy: A multi-center study in Hong Kong
    Peter YM Woo, Clara KW Lee, Lai‐Fung Li et al. · 2026 · Neuro-Oncology Advances
  41. Acetylation modification in malignant progression and therapeutic resistance of gliomas
    Jiayi Zhang, Mengying Wang, Hong Wang, Xuemei Jiang, Hanyan Zou · 2026 · Frontiers in Cell and Developmental Biology
  42. Développement et caractérisation de modèles vitro et vivo de cancers pédiatriques infiltrant du tronc cérébral (DIPG)
    Alexandre Plessier · 2018 · theses.fr (ABES)
  43. The tale of the histone H3.3 tail An essential role for the histone variant H3.3S31 residue during gastrulation in Xenopus
    David Sitbon · 2018 · theses.fr (ABES)
  44. Role of histone variant H3.3 mutations in the development of pediatric high-grade glioma
    Alexia Vidal · 2019 · theses.fr (ABES)
  45. Modélisation in vitro & in vivo de la résistance à la radiothérapie dans les gliomes infiltrants du tronc cérébral (DIPG)
    Coralie Werbrouck · 2020 · theses.fr (ABES)
  46. Exon-Skipping Antisense Oligonucleotides for H3.3K27M-Altered Diffuse Midline Glioma Therapy
    Lucia Yang, Qian Zhang, John Erby Wilkinson, Adrian R. Krainer · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  47. Dérégulations épigénétiques et maintien de l'intégrité du génome dans les gliomes pédiatriques mutés H3-K27M (DMG)
    Chloé Subecz · 2023 · theses.fr (ABES)
  48. Nouvelles stratégies thérapeutiques dans le traitement du gliome infiltrant du tronc cérébral
    Guillaume Herrault · 2024 · theses.fr (ABES)
  49. Histone mark remodeling in cancer: an enhancer-centered perspective
    Jiyoon Park, 전진하, Sujeong Gim, Chan Chung · 2026 · Genes & Genomics
  50. Evidence for coordinate CTCF and histone H3.3 activities in K27M diffuse midline gliomas
    Rachel Herndon Klein, Jennifer Q. Yee, Paul S. Knoepfler · 2026 · Acta Neuropathologica Communications
  51. H3K27M-altered diffuse midline glioma: Experience and outcomes from a low-middle income country setting in the contemporary era
    Meenakshi Jeeva, Mamta Gurav, Abhishek Chatterjee et al. · 2026 · Neuro-Oncology Advances
  52. Elongin B orchestrates chromatin and transcriptional programs in H3K27M-mutant diffuse midline glioma
    Alan L. Jiao, Rebecca L. Murdaugh, Adam Fiseha Kebede, Claudia A. Mimoso, Barry M. Zee, Rosemary U. Richard, Kwanha Yu, Caitlin L. Bagnetto, Karen Adelman, Mariella G. Filbin et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  53. Selective histone deacetylase inhibition as a therapeutically relevant strategy in H3K27M-glioma
    Andrew Groves, Orville O. Kirkland, Costanza Lo Cascio, Xiuqi Wang, Caleb Heaslip, Joana Graca Marques, Chen Song, Rebecca Poetschke, Tingjian Wang, Diana H. Chin et al. · 2026 · Neuro-Oncology
  54. Overview of transcriptomics and epigenomics approaches in the diagnosis, prognosis, and therapeutics of primary brain cancers
    Luna Guerra-Núñez, David Hughes-Herrera, Juan Manuel Molina-López, Luis Miguel Valor · 2026 · Epigenomics
  55. Mapping epigenetic alterations across brain tumor hallmarks
    Celeste Antonacci, Luana Abballe, Angela Di Giannatale, Evelina Miele · 2026 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  56. Exon-skipping antisense oligonucleotides for H3.3K27M-altered diffuse midline glioma therapy
    Lucia Yang, Qian Zhang, John Erby Wilkinson, Shivani Deshpande, Adrian R. Krainer · 2026 · Molecular Therapy — Nucleic Acids
  57. Histone tail mutants: versatile tools for decoding chromatin, development, and disease
    Masaki Yagi, Xiangle Ren, Konrad Hochedlinger · 2026 · Trends in Genetics
  58. Combination of ALK2 and cholesterol targeting agents exploits linked genetic and metabolic dependencies in diffuse midline glioma
    Rebecca Rogers, Alan G. Mackay, Yura Grabovska, Diana Carvalho, Claire Dobinson, Anna Burford, Valeria Molinari, Rita Pereira, Laura Bevington, Ruth Ruddle et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)