Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy

Muller, Alexander J, DuHadaway, James B, Donover, P Scott, Sutanto-Ward, Erika, Prendergast, George C·2005·Nature Medicine

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  12. High-Throughput Fluorescence-Based Screening Assays for Tryptophan-Catabolizing Enzymes
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  13. O-alkylhydroxylamines as rationally-designed mechanism-based inhibitors of indoleamine 2,3-dioxygenase-1
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  16. Indoleamine 2,3-Dioxygenase Expression Pattern in the Tumor Microenvironment Predicts Clinical Outcome in Early Stage Cervical Cancer
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  17. Structural Basis of Inhibitor Selectivity in Human Indoleamine 2,3-Dioxygenase 1 and Tryptophan Dioxygenase
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  30. Indoximod opposes the immunosuppressive effects mediated by IDO and TDO via modulation of AhR function and activation of mTORC1
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  31. Inhibitors of indoleamine 2,3-dioxygenase: a review of novel patented lead compounds
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  35. Inhibition of Indoleamine 2,3-Dioxygenase Enhances the Therapeutic Efficacy of Immunogenic Chemotherapeutics in Breast Cancer
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  36. Recent advances in the discovery of indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors
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    Liancai Wang, Han Liu, Xiangli Chen, Min Zhang, Keping Xie, Qingyong Ma · 2012 · PLoS ONE
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    Daniel Delitto, Shannon Margaret Wallet, Steven J. Hughes · 2016 · Pharmacology & Therapeutics
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    Eduardo Vottero, David A. Mitchell, Michael J. Page, Ross T. A. MacGillivray, Ivan Sadowski, Michel Roberge, A. Grant Mauk · 2006 · FEBS Letters
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    Zhentai Huang, Michael W. Epperly, Simon C. Watkins, Joel S. Greenberger, Valerian E. Kagan, Hülya Bayır · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
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    Le Zhang, Shiwei Fan, Julio Vera, Xin Lai · 2022 · Computational and Structural Biotechnology Journal
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  49. Harnessing the immune system for the treatment of breast cancer
    Xinguo Jiang · 2014 · Journal of Zhejiang University SCIENCE B
  50. Enhancing the efficacy of cancer vaccines in urologic oncology: new directions
    Sergei A. Kusmartsev, Johannes Vieweg · 2009 · Nature Reviews Urology
  51. A combination of the metabolic enzyme inhibitor APO866 and the immune adjuvant L-1-methyl tryptophan induces additive antitumor activity
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  70. Identification of potent virtual leads to design novel indoleamine 2,3-dioxygenase inhibitors: pharmacophore modeling and molecular docking studies.
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  99. Manipulation of indoleamine 2,3 dioxygenase; a novel therapeutic target for treatment of diseases
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