Intranasal delivery of the cytoplasmic domain of CTLA-4 using a novel protein transduction domain prevents allergic inflammation

In Vivo Protein Transduction: Delivery of a Biologically Active Protein into the Mouse

Schwarze, S. R., Ho, A. L., Vocero-Akbani, A. M., & Dowdy, S. F. (1999) · Science · doi:10.1126/science.285.5433.1569 · Cited by 2,418 · see citing works

Asthma: From Bronchoconstriction to Airways Inflammation and Remodeling

BOUSQUET, J., JEFFERY, P. K., BUSSE, W. W., JOHNSON, M., & VIGNOLA, A. M. (2000) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.161.5.9903102 · Cited by 1,702 · see citing works

Immune Inhibitory Receptors

Ravetch, J. V., & Lanier, L. L. (2000) · Science · doi:10.1126/science.290.5489.84 · Cited by 1,278 · see citing works

IMMUNOLOGIC BASIS OF ANTIGEN-INDUCED AIRWAY HYPERRESPONSIVENESS

Wills-Karp, M. A. (1999) · Annual Review of Immunology · doi:10.1146/annurev.immunol.17.1.255 · Cited by 1,027 · see citing works

Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration

Nagahara, H., Vocero-Akbani, A. M., Snyder, E. L., Ho, A. L., Latham, D. G., Lissy, N. A., Becker‐Hapak, M., Ezhevsky, S. A., & Dowdy, S. F. (1998) · Nature Medicine · doi:10.1038/4042 · Cited by 928 · see citing works

Molecular Basis of T Cell Inactivation by CTLA-4

Lee, K.-M., Chuang, E., Griffin, M., Khattri, R., Hong, D. K., Zhang, W., Straus, D., Samelson, L. E., Thompson, C. B., & Bluestone, J. A. (1998) · Science · doi:10.1126/science.282.5397.2263 · Cited by 684 · see citing works

Interleukin‐13 in asthma pathogenesis

Wills‐Karp, M. (2004) · Immunological Reviews · doi:10.1111/j.0105-2896.2004.00215.x · Cited by 683 · see citing works

The Emerging Role of CTLA-4 as an Immune Attenuator

Thompson, C. B., & Allison, J. P. (1997) · Immunity · doi:10.1016/s1074-7613(00)80366-0 · Cited by 633 · see citing works

A MOLECULAR PERSPECTIVE OF CTLA-4 FUNCTION

Teft, W. A., Kirchhof, M. G., & Madrenas, J. (2005) · Annual Review of Immunology · doi:10.1146/annurev.immunol.24.021605.090535 · Cited by 518 · see citing works

Interleukin-5 Expression in the Lung Epithelium of Transgenic Mice Leads to Pulmonary Changes Pathognomonic of Asthma

Lee, J. J., McGarry, M. P., Farmer, S. C., Denzler, K. L., Larson, K. A., Carrigan, P. E., Brenneise, I. E., Horton, M. A., Haczku, A., Gelfand, E. W., et al. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.185.12.2143 · Cited by 517 · see citing works

TAT-Mediated Protein Transduction into Mammalian Cells

Becker‐Hapak, M., McAllister, S. S., & Dowdy, S. F. (2001) · Methods · doi:10.1006/meth.2001.1186 · Cited by 384 · see citing works

CD4+ T-Lymphocytes and Interleukin-5 Mediate Antigen-induced Eosinophil Infiltration into the Mouse Trachea

Nakajima, H., Iwamoto, I., Tomoe, S., Matsumura, R., Tomioka, H., Takatsu, K., & Yoshida, S. (1992) · American Review of Respiratory Disease · doi:10.1164/ajrccm/146.2.374 · Cited by 346 · see citing works

Blockade of Inflammation and Airway Hyperresponsiveness in Immune-sensitized Mice by Dominant-Negative Phosphoinositide 3-Kinase–TAT

Myou, S., Leff, A. R., Myo, S., Boetticher, E., Tong, J., Meliton, A. Y., Liu, J., Muñoz, N. M., & Zhu, X. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030298 · Cited by 259 · see citing works

An Autoimmune Disease-Associated CTLA-4 Splice Variant Lacking the B7 Binding Domain Signals Negatively in T Cells

Vijayakrishnan, L., Slavik, J. M., Illés, Z., Greenwald, R. J., Rainbow, D., Greve, B., Peterson, L. B., Hafler, D. A., Freeman, G. J., Sharpe, A. H., et al. (2004) · Immunity · doi:10.1016/s1074-7613(04)00110-4 · Cited by 218 · see citing works

Inhibitory receptors, ITIM sequences and phosphatases

Unkeless, J. C., & Jin, J. (1997) · Current Opinion in Immunology · doi:10.1016/s0952-7915(97)80079-9 · Cited by 154 · see citing works

Cytotoxic T Lymphocyte Antigen 4 (CTLA-4) Interferes with Extracellular Signal-regulated Kinase (ERK) and Jun NH2-terminal Kinase (JNK) Activation, but Does Not Affect Phosphorylation of T Cell Receptor ζ and ZAP70

Revilla, C., Amsen, D., & Kruisbeek, A. M. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.186.10.1645 · Cited by 151 · see citing works

Contribution of Vascular Endothelial Growth Factor to Airway Hyperresponsiveness and Inflammation in a Murine Model of Toluene Diisocyanate-Induced Asthma

Lee, Y. C., Kwak, Y., & Song, C. H. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.7.3595 · Cited by 148 · see citing works

Tryptase Inhibition Blocks Airway Inflammation in a Mouse Asthma Model

Oh, S., Pae, C. I., Lee, D.-K., Jones, F., Chiang, G. K. S., Kim, H.-O., Moon, S., Cao, B., Ogbu, C. O., Jeong, K.-W., et al. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.4.1992 · Cited by 131 · see citing works

Allergen-induced accumulation of airway dendritic cells is supported by an increase in CD31hiLy-6Cneg bone marrow precursors in a mouse model of asthma

van Rijt, L. S., Prins, J., Leenen, P. J. M., Thielemans, K., de Vries, V. C., Hoogsteden, H. C., & Lambrecht, B. N. (2002) · Blood · doi:10.1182/blood-2002-03-0673 · Cited by 129 · see citing works

CTLA-4 Suppresses Proximal TCR Signaling in Resting Human CD4+ T Cells by Inhibiting ZAP-70 Tyr319 Phosphorylation: A Potential Role for Tyrosine Phosphatases

Guntermann, C., & Alexander, D. R. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.9.4420 · Cited by 127 · see citing works

Tyrosine Phosphatase SHP-2 Binding to CTLA-4: Absence of Direct YVKM/YFIP Motif Recognition

Schneider, H., & Rudd, C. E. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.2234 · Cited by 78 · see citing works

B7-Independent Inhibition of T Cells by CTLA-4

Chikuma, S., Abbas, A. K., & Bluestone, J. A. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.1.177 · Cited by 78 · see citing works

Involvement of the SHP-1 Tyrosine Phosphatase in Regulation of T Cell Selection

Zhang, J., Somani, A.-K. B., Yuen, D. A., Yang, Y., Love, P. E., & Siminovitch, K. A. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.6.3012 · Cited by 68 · see citing works

Complement Activation Is Critical to Airway Hyperresponsiveness after Acute Ozone Exposure

Park, J., Taube, C., Joetham, A., Takeda, K., Kodama, T., Dakhama, A., McConville, G., Allen, C. B., Sfyroera, G., Shultz, L., et al. (2004) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200307-1042oc · Cited by 54 · see citing works

Isolation of peripheral blood CD4+ T cells using RosetteSep™ and MACS™ for studies of DNA turnover by deuterium labeling

Busch, R., Cesar, D., Higuera‐Alhino, D., Gee, T. A., Hellerstein, M. K., & McCune, J. M. (2004) · Journal of Immunological Methods · doi:10.1016/j.jim.2003.12.012 · Cited by 35 · see citing works

Transduction of the TAT-FLIP Fusion Protein Results in Transient Resistance to Fas-induced Apoptosis in Vivo

Krautwald, S., Ziegler, E., Tiede, K., Pust, R. A., & Kunzendorf, U. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m401327200 · Cited by 26 · see citing works

Blockade of Airway Inflammation and Hyperresponsiveness by HIV-TAT-Dominant Negative Ras

Myou, S., Zhu, X., Myo, S., Boetticher, E., Meliton, A. Y., Liu, J., Muñoz, N. M., & Leff, A. R. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.8.4379 · Cited by 25 · see citing works

Tyrosine-mediated inhibitory signals contribute to CTLA-4 function in vivo

Yi, L. (2004) · International Immunology · doi:10.1093/intimm/dxh055 · Cited by 24 · see citing works

The glucocorticoid inhibition of LFA-1 and CD2 expression by human mononuclear cells is reversed by IL-2, IL-7 and IL-15

Pipitone, N., Sinha, M., Theodoridis, E., Goulding, N. J., Hall, M. D., Lanchbury, J. S. S., Corrigall, V., Panayi, G. S., & Pitzalis, C. (2001) · European Journal of Immunology · doi:10.1002/1521-4141(200107)31:7 · Cited by 19 · see citing works

Transduction of naive CD4 T cells with kinase‐deficient Lck‐HIV‐Tat fusion protein dampens T cell activation and provokes a switch to regulatory function

Veldhoen, M., Magee, A. I., Penha‐Goncalves, M. N., & Stockinger, B. (2004) · European Journal of Immunology · doi:10.1002/eji.200425542 · Cited by 6 · see citing works

Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4

Qureshi, O. S., Zheng, Y., Nakamura, K., Attridge, K., Manzotti, C., Schmidt, E. M., Baker, J., Jeffery, L. E., Kaur, S., Briggs, Z., et al. (2011) · Science · doi:10.1126/science.1202947 · Cited by 1,860 · see citing works

Combination strategies with PD-1/PD-L1 blockade: current advances and future directions

Yi, M., Zheng, X., Niu, M., Zhu, S., Ge, H., & Wu, K. (2022) · Molecular Cancer · doi:10.1186/s12943-021-01489-2 · Cited by 1,445 · see citing works

Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery

Nicolas, J., Mura, S., Brambilla, D., Mackiewicz, N., & Couvreur, P. (2013) · Chem. Soc. Rev. · doi:10.1039/c2cs35265f · Cited by 1,270 · see citing works

The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses

Walker, L. S. K., & Sansom, D. M. (2011) · Nature reviews. Immunology · doi:10.1038/nri3108 · Cited by 786 · see citing works

CTLA-4 blockade in tumor models: an overview of preclinical and translational research.

Grosso, J. F., & Jure‐Kunkel, M. (2013) · Europe PMC (PubMed Central) · Cited by 335 · see citing works

Engineering lymphocyte subsets: tools, trials and tribulations

June, C. H., Blazar, B. R., & Riley, J. L. (2009) · Nature reviews. Immunology · doi:10.1038/nri2635 · Cited by 199 · see citing works

The Nuclear Receptor PPARs as Important Regulators of T-Cell Functions and Autoimmune Diseases

Choi, J., & Bothwell, A. L. M. (2012) · Molecules and Cells · doi:10.1007/s10059-012-2297-y · Cited by 178 · see citing works

Cell-Penetrating Peptide-Mediated Delivery of TALEN Proteins via Bioconjugation for Genome Engineering

Liu, J., Gaj, T., Patterson, J. T., Sirk, S. J., & Barbas, C. F. (2014) · PLoS ONE · doi:10.1371/journal.pone.0085755 · Cited by 147 · see citing works

Molecular mechanisms of IgE mediated food allergy

Kumar, S., Verma, A. K., Das, M., & Dwivedi, P. D. (2012) · International Immunopharmacology · doi:10.1016/j.intimp.2012.05.018 · Cited by 124 · see citing works

Current Understanding of Cytotoxic T Lymphocyte Antigen-4 (CTLA-4) Signaling in T-Cell Biology and Disease Therapy

Kim, G., & Choi, J. (2022) · Molecules and Cells · doi:10.14348/molcells.2022.2056 · Cited by 124 · see citing works

The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils

Honda, F., Kano, H., Kanegane, H., Nonoyama, S., Kim, E. S., Lee, S., Takagi, M., Mizutani, S., & Morio, T. (2012) · Nature Immunology · doi:10.1038/ni.2234 · Cited by 120 · see citing works

dNP2 is a blood–brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis

Lim, S., Kim, W., Kim, Y.-H., Lee, S., Koo, J., Lee, J.-A., Yoon, H., Kim, D.-H., Park, H.-J., Kim, H.-M., et al. (2015) · Nature Communications · doi:10.1038/ncomms9244 · Cited by 119 · see citing works

A Transendocytosis Model of CTLA-4 Function Predicts Its Suppressive Behavior on Regulatory T Cells

Hou, T. Z., Qureshi, O., Wang, C. J., Baker, J., Young, S. P., Walker, L. S. K., & Sansom, D. M. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1401876 · Cited by 115 · see citing works

Selective inhibition of RANK blocks osteoclast maturation and function and prevents bone loss in mice

Kim, H., Choi, H. K., Shin, J. H., Kim, K., Huh, J. Y., Lee, S. A., Ko, C., Kim, H.-S., Shin, H.-I., Jeong, D., et al. (2009) · Journal of Clinical Investigation · doi:10.1172/jci36809 · Cited by 106 · see citing works

Intracellular Trafficking and Unpacking of siRNA/Quantum Dot-PEI Complexes Modified with and without Cell Penetrating Peptide: Confocal and Flow Cytometric FRET Analysis

Lee, H., Kim, I.-K., & Park, T. G. (2010) · Bioconjugate Chemistry · doi:10.1021/bc900342p · Cited by 99 · see citing works

Celastrol suppresses allergen-induced airway inflammation in a mouse allergic asthma model

Kim, D. Y., Park, J., Jeoung, D., & Ro, J. Y. (2009) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2009.03.078 · Cited by 99 · see citing works

PEGylated and MMP-2 Specifically DePEGylated Quantum Dots: Comparative Evaluation of Cellular Uptake

Mok, H., Bae, K. H., Ahn, C., & Park, T. G. (2008) · Langmuir · doi:10.1021/la803542v · Cited by 99 · see citing works

Mesenchymal Stem Cells Pretreated with Delivered Hph-1-Hsp70 Protein Are Protected from Hypoxia-Mediated Cell Death and Rescue Heart Functions from Myocardial Injury

Chang, W., Song, B., Lim, S., Song, H., Shim, C. Y., Cha, M., Ahn, D. H., Jung, Y.-G., Lee, D.-H., Chung, J. H., et al. (2009) · Stem Cells · doi:10.1002/stem.153 · Cited by 91 · see citing works

Inhibition of Multiple Subtypes of Influenza A Virus in Cell Cultures with Morpholino Oligomers

Ge, Q., Pastey, M. K., Kobasa, D., Puthavathana, P., Lupfer, C. R., Bestwick, R. K., Iversen, P. L., Chen, J., & Stein, D. A. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00644-06 · Cited by 89 · see citing works

Redesigning of Cell-Penetrating Peptides to Improve Their Efficacy as a Drug Delivery System

Szabó, I., Yousef, M., Soltész, D. B., Bató, C., Mező, G., & Bánóczi, Z. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14050907 · Cited by 80 · see citing works

Multifunctional siRNA delivery system: Polyelectrolyte complex micelles of six‐arm PEG conjugate of siRNA and cell penetrating peptide with crosslinked fusogenic peptide

Choi, S. W., Hyeon, L. S., Mok, H., & Park, T. G. (2009) · Biotechnology Progress · doi:10.1002/btpr.310 · Cited by 74 · see citing works

Immune Checkpoint Receptors Signaling in T Cells

Baldanzi, G. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073529 · Cited by 71 · see citing works

Mesenchymal Stem Cell Transfer Suppresses Airway Remodeling in a Toluene Diisocyanate-Induced Murine Asthma Model

Lee, S., Jang, A., Kwon, J.-H., Park, S.-K., Won, J.-H., & Park, C. (2011) · Allergy Asthma and Immunology Research · doi:10.4168/aair.2011.3.3.205 · Cited by 69 · see citing works

Harnessing the power of cell‐penetrating peptides: activatable carriers for targeting systemic delivery of cancer therapeutics and imaging agents

MacEwan, S. R., & Chilkoti, A. (2012) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1197 · Cited by 63 · see citing works

Intracellular Delivery of Molecular Cargo Using Cell-Penetrating Peptides and the Combination Strategies

Li, H., Tsui, T. Y., & Ma, W. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms160819518 · Cited by 61 · see citing works

Thermally Triggered Cellular Uptake of Quantum Dots Immobilized with Poly(N-isopropylacrylamide) and Cell Penetrating Peptide

Kim, C.-S., Lee, Y., Kim, J. S., Jeong, J. H., & Park, T. G. (2010) · Langmuir · doi:10.1021/la102632m · Cited by 56 · see citing works

Apolipoprotein A1 potentiates lipoxin A4 synthesis and recovery of allergen‐induced disrupted tight junctions in the airway epithelium

Park, S. ‐., Lee, E. H., Lee, E., Kim, H. J., Bae, D. J., Han, S., Kim, D., Jang, A., Uh, S., Kim, Y., et al. (2013) · Clinical & Experimental Allergy · doi:10.1111/cea.12143 · Cited by 56 · see citing works

Use of Cell-Penetrating Peptides in Dendritic Cell-Based Vaccination

Lim, S., Koo, J., & Choi, J. (2016) · Immune Network · doi:10.4110/in.2016.16.1.33 · Cited by 54 · see citing works

Development of DG9 peptide-conjugated single- and multi-exon skipping therapies for the treatment of Duchenne muscular dystrophy

Lim, K. R. Q., Woo, S., Melo, D., Huang, Y., Dzierlega, K., Shah, M. N. A., Aslesh, T., Roshmi, R. R., Echigoya, Y., Maruyama, R., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2112546119 · Cited by 52 · see citing works

Branched oligomerization of cell-permeable peptides markedly enhances the transduction efficiency of adenovirus into mesenchymal stem cells

Park, S.-H., Doh, J., Park, S. I., Lim, J. Y., Kim, S. M., Youn, J. Y., Jin, H.-T., Seo, S.-H., Song, M.-Y., Sung, S. Y., et al. (2010) · Gene Therapy · doi:10.1038/gt.2010.58 · Cited by 45 · see citing works

RORγt-specific transcriptional interactomic inhibition suppresses autoimmunity associated with T H 17 cells

Park, T. Y., Park, S.-D., Cho, J.-Y., Moon, J., Kim, N.-Y., Park, K., Seong, R. H., Lee, S., Morio, T., Bothwell, A. L. M., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1413687112 · Cited by 45 · see citing works

Anti‐inflammatory effects of the R2 peptide, an inhibitor of transglutaminase 2, in a mouse model of allergic asthma, induced by ovalbumin

Kim, D. Y., Park, B. S., Hong, G. U., Lee, B., Park, J., Kim, S. Y., & Ro, J. Y. (2010) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2010.01033.x · Cited by 44 · see citing works

Intracellular delivery of paclitaxel using oil-free, shell cross-linked HSA – Multi-armed PEG nanocapsules

Lee, J. Y., Bae, K. H., Kim, J. S., Nam, Y. S., & Park, T. G. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.07.063 · Cited by 44 · see citing works

Effects of Interleukin-9 Blockade on Chronic Airway Inflammation in Murine Asthma Models

Kim, M., Cho, K., Cho, Y.-J., & Woo, S. (2013) · Allergy Asthma and Immunology Research · doi:10.4168/aair.2013.5.4.197 · Cited by 44 · see citing works

A protein delivery system using 30Kc19 cell-penetrating protein originating from silkworm

Park, J. H., Lee, J. H., Park, H. H., Rhee, W. J., Choi, S. S., & Park, T. H. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.08.063 · Cited by 42 · see citing works

Transduction of the cytoplasmic domain of CTLA-4 inhibits TcR-specific activation signals and prevents collagen-induced arthritis

Choi, J., Kim, S., Shin, J.-H., Gibson, T. F., Yoon, B.-S., Lee, D., Lee, S.-K., Bothwell, A. L. M., Lim, J.-S., & Lee, S. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0805198105 · Cited by 41 · see citing works

Bioportide: an emergent concept of bioactive cell-penetrating peptides

Howl, J., Matou‐Nasri, S., West, D. C., Farquhar, M. J., Slaninová, J., Östenson, C., Zorko, M., Östlund, P., Kumar, S., Langel, Ü., et al. (2012) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-012-0979-4 · Cited by 40 · see citing works

Efficient therapeutic delivery by a novel cell-permeant peptide derived from KDM4A protein for antitumor and antifibrosis

Wang, H., Ma, J.-L., Yang, Y., Song, Y., Wu, J., Qin, Y., Zhao, X., Wang, J., Zou, L., Wu, J., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.8682 · Cited by 40 · see citing works

Optical imaging of intracellular reactive oxygen species for the assessment of the cytotoxicity of nanoparticles

Lee, K., Lee, H., Lee, K. W., & Park, T. G. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2010.11.072 · Cited by 39 · see citing works

Evaluation of the effect of kaempferol in a murine allergic rhinitis model

Oh, H., Han, N., Kim, M. J., Kim, H., & Jeong, H. (2013) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2013.08.045 · Cited by 39 · see citing works

Unleashing cell-penetrating peptide applications for immunotherapy

Koo, J., Kim, G., Nam, K.-H., & Choi, J. (2022) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2022.03.010 · Cited by 39 · see citing works

Controlled release of cell-permeable gene complex from poly(L-lactide) scaffold for enhanced stem cell tissue engineering

Jung, M.-R., Shim, I. K., Kim, E. S., Park, Y., Yang, Y., Lee, S., & Lee, S. J. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.03.002 · Cited by 39 · see citing works

Enhancing Antisense Oligonucleotide-Based Therapeutic Delivery with DG9, a Versatile Cell-Penetrating Peptide

Haque, U. S., & Yokota, T. (2023) · Cells · doi:10.3390/cells12192395 · Cited by 38 · see citing works

Cell-Penetrating Mx1 Enhances Anti-Viral Resistance against Mucosal Influenza Viral Infection

Jung, H. E., Oh, J. E., & Lee, H. K. (2019) · Viruses · doi:10.3390/v11020109 · Cited by 34 · see citing works

Cell-penetrating interactomic inhibition of nuclear factor-kappa B in a mouse model of postoperative cognitive dysfunction

Cheon, S. Y., Kim, J., Kam, E. H., Ho, C.-C., Kim, E. J., Chung, S., Jeong, J., Lee, D. D.-H., Lee, S., & Koo, B. (2017) · Scientific Reports · doi:10.1038/s41598-017-14027-2 · Cited by 34 · see citing works

Enhanced delivery efficiency of recombinant adenovirus into tumor and mesenchymal stem cells by a novel PTD

Youn, J. Y., Park, S.-H., Jin, H.-T., Lee, C.-G., Seo, S.-H., Song, M.-Y., Lee, C.-W., & Sung, Y.-C. (2008) · Cancer Gene Therapy · doi:10.1038/cgt.2008.45 · Cited by 33 · see citing works

The therapeutic effects of tuberostemonine against cigarette smoke-induced acute lung inflammation in mice

Jung, K., Beak, H., Park, S., Shin, D., Jung, J., Park, S., Kim, J., & Bae, H. (2016) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2016.02.006 · Cited by 32 · see citing works

Bioportides: Bioactive cell‐penetrating peptides that modulate cellular dynamics

Lukanowska, M., Howl, J., & Jones, S. (2013) · Biotechnology Journal · doi:10.1002/biot.201200335 · Cited by 32 · see citing works

Highly efficient delivery of siRNA to a heart transplant model by a novel cell penetrating peptide-dsRNA binding domain

Li, H., Zheng, X., Koren, V., Vashist, Y. K., & Tsui, T. Y. (2014) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2014.04.050 · Cited by 30 · see citing works

Skin‐penetrating methotrexate alleviates imiquimod‐induced psoriasiform dermatitis via decreasing IL ‐17‐producing gamma delta T cells

Byamba, D., ‍Kim, D. Y., Kim, D., Kim, T., Jee, H., Kim, S. H., Park, T. Y., Yang, S., Lee, S., & Lee, M. (2014) · Experimental Dermatology · doi:10.1111/exd.12448 · Cited by 30 · see citing works

Highly Efficient Delivery of Functional Cargoes by a Novel Cell-Penetrating Peptide Derived from SP140-Like Protein

Wang, H., Ma, J.-L., Yang, Y., Zeng, F., & Liu, C.-B. (2016) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.6b00161 · Cited by 30 · see citing works

TCR-Driven Transendothelial Migration of Human Effector Memory CD4 T Cells Involves Vav, Rac, and Myosin IIA

Manes, T. D., & Pober, J. S. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1201817 · Cited by 28 · see citing works

Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein Receptor-Derived Peptides for Regulation of Mast Cell Degranulation

Yang, Y., Kong, B., Jung, Y. H., Park, J.-B., Oh, J.-M., Hwang, J., Cho, J. Y., & Kweon, D. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00725 · Cited by 28 · see citing works

Intracellular ATP Assay of Live Cells Using PTD-Conjugated Luciferase

Lee, M., Park, W.-S., Kim, Y., Ahn, W. G., Kwon, S., & Her, S. (2012) · Sensors · doi:10.3390/s121115628 · Cited by 27 · see citing works

Chronic inflammation in asthma: a contest of persistence vs resolution

Hove, C. L. V., Maes, T., Joos, G., & Tournoy, K. G. (2008) · Allergy · doi:10.1111/j.1398-9995.2008.01772.x · Cited by 27 · see citing works

Cell-permeable mitochondrial ubiquinol–cytochrome c reductase binding protein induces angiogenesis in vitro and in vivo

Chang, J., Jung, H. J., Park, H.-J., Cho, S., Lee, S., & Kwon, H. J. (2015) · Cancer Letters · doi:10.1016/j.canlet.2015.06.013 · Cited by 26 · see citing works

Targeting MCM2 function as a novel strategy for the treatment of highly malignant breast tumors

Abe, S., Yamamoto, K., Kurata, M., Abe‐Suzuki, S., Horii, R., Akiyama, F., & Kitagawa, M. (2015) · Oncotarget · doi:10.18632/oncotarget.5408 · Cited by 26 · see citing works

Identification of a Novel Cell-Penetrating Peptide from Human Phosphatidate Phosphatase LpIN3

Lim, S., Kim, W., Kim, Y., & Choi, J. (2012) · Molecules and Cells · doi:10.1007/s10059-012-0284-y · Cited by 25 · see citing works

Cytotoxic T-Lymphocyte Associated Antigen 4 Polymorphisms and Asthma Risk: A Meta-Analysis

Nie, W., Chen, J., & Xiu, Q. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042062 · Cited by 25 · see citing works

Immune Tolerance Induction by Integrating Innate and Adaptive Immune Regulators

Suzuki, J., Ricordi, C., & Chen, Z. (2010) · Cell Transplantation · doi:10.3727/096368909x480314 · Cited by 25 · see citing works

Recombinant expression and purification of a MAP30-cell penetrating peptide fusion protein with higher anti-tumor bioactivity

Lv, Q., Yang, X., Fu, L., Lu, Y.-T., Lü, Y., Zhao, J., & Wang, F. (2015) · Protein Expression and Purification · doi:10.1016/j.pep.2015.03.008 · Cited by 24 · see citing works

Cell-penetrating peptides and proteins: new inhibitors of allergic airways diseaseThis review is an invited paper from 2007 ICRH Leadership in Science: a Forum for Trainees and New Investigators.

Kinyanjui, M. W., & Fixman, E. D. (2008) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y07-125 · Cited by 24 · see citing works

Decrease of GSK 3β phosphorylation in the rat nucleus accumbens core enhances cocaine‐induced hyper‐locomotor activity

Kim, W. Y., Jang, J. K., Lee, J. W., Jang, H., & Kim, J. (2013) · Journal of Neurochemistry · doi:10.1111/jnc.12222 · Cited by 24 · see citing works

Intranuclear interactomic inhibition of NF-κB suppresses LPS-induced severe sepsis

Park, S.-D., Cheon, S. Y., Park, T. Y., Shin, B.-Y., Oh, H.-J., Ghosh, S., Koo, B., & Lee, S. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.07.008 · Cited by 24 · see citing works

Cell permeable NFAT inhibitory peptide Sim-2-VIVIT inhibits T-cell activation and alleviates allergic airway inflammation and hyper-responsiveness

Choi, J., Sohn, J.-H., Park, T. Y., Park, J., & Lee, S. (2012) · Immunology Letters · doi:10.1016/j.imlet.2012.01.016 · Cited by 24 · see citing works

Specific RANK Cytoplasmic Motifs Drive Osteoclastogenesis

Li, Y., Shi, Z., Jules, J., Chen, S., Kesterson, R. A., Zhao, D., Zhang, P., & Feng, X. (2019) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3810 · Cited by 23 · see citing works

The standardized herbal formula, PM014, ameliorated cigarette smoke-induced lung inflammation in a murine model of chronic obstructive pulmonary disease

Jung, K., Haam, K.-K., Park, S., Kim, Y., Lee, S. R., Lee, G., Kim, M., Hong, M., Shin, M., Jung, S., et al. (2013) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-13-219 · Cited by 22 · see citing works

Alleviating psoriatic skin inflammation through augmentation of Treg cells via CTLA-4 signaling peptide

Lee, W.-S., Nam, K.-H., Kim, J. H., Kim, W., Kim, J. E., Shin, E., Kim, G., & Choi, J. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1233514 · Cited by 21 · see citing works

Cell-penetrating DNA-binding protein as a safe and efficient naked DNA delivery carrier in vitro and in vivo

Kim, E. S., Yang, S., Hong, D.-K., Kim, W.-T., Kim, H.-G., & Lee, S. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.12.135 · Cited by 21 · see citing works

Quantification of cellular uptake and in vivo tracking of transduction using real-time monitoring

Lee, M.-S., Kwon, E.-H., Choi, H. S., Kwon, S., Lee, C.-H., Shim, I., Lee, S., & Her, S. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.03.009 · Cited by 20 · see citing works

Relationship between Group-Specific Component Protein and the Development of Asthma

Lee, S., Kim, K.-H., Kim, J.-M., Yoon, S., Kim, T. H., Park, S., Park, J., Uh, S., Lee, H. S., Kim, Y. H., et al. (2010) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201006-0951oc · Cited by 20 · see citing works

Force-dependent trans-endocytosis by breast cancer cells depletes costimulatory receptor CD80 and attenuates T cell activation

Park, S., Shi, Y., Kim, B. C., Jo, M. H., Cruz, L. O., Gou, Z., Ha, T., Lu, L., Reich, D. H., & Chen, Y. (2020) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2020.112389 · Cited by 20 · see citing works

Effects of 7,8‐dihydro‐8‐oxo‐deoxyguanosine on antigen challenge in ovalbumin‐sensitized mice may be mediated by suppression of Rac

Ro, J., Kim, D., Lee, S., Park, J., & Chung, M. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2009.00436.x · Cited by 20 · see citing works

Amelioration of neurodegenerative diseases by cell death-induced cytoplasmic delivery of humanin

Park, T. Y., Kim, S., Shin, Y.-C., Lee, N.-H., Lee, R.-K. C., Shim, J., Glimcher, L. H., Mook‐Jung, I., Cheong, E., Kim, W.-K., et al. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.12.022 · Cited by 20 · see citing works

Cell Type Preference of a Novel Human Derived Cell-Permeable Peptide dNP2 and TAT in Murine Splenic Immune Cells

Lim, S., Lee, J.-A., Koo, J., Kang, T. G., Ha, S., & Choi, J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0155689 · Cited by 19 · see citing works

DG9-conjugated morpholino rescues phenotype in SMA mice by reaching the CNS via a subcutaneous administration

Aslesh, T., Erkut, E. J. N., Ren, J. T., Lim, K. R. Q., Woo, S., Hatlevig, S. A., Moulton, H. M., Gosgnach, S., Greer, J. J., Maruyama, R., et al. (2023) · JCI Insight · doi:10.1172/jci.insight.160516 · Cited by 19 · see citing works

Regulation of keratinocyte differentiation by O-GlcNAcylation

Sohn, K., Lee, E. J., Shin, J., Lim, E.-H., No, Y., Lee, J. Y., Yoon, T. Y., Lee, Y., Im, M., Lee, Y., et al. (2014) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2014.04.010 · Cited by 18 · see citing works

HIF1A overexpression using cell-penetrating DNA-binding protein induces angiogenesis in vitro and in vivo

Jeon, M., Shin, Y., Jung, J., Jung, U., Lee, J. H., Moon, J., Kim, I.-K., Shin, J.-S., Lee, S., & Song, J. S. (2017) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-017-3098-6 · Cited by 18 · see citing works

Identification and characterization of a novel cell-penetrating peptide of 30Kc19 protein derived from Bombyx mori

Park, H. H., Sohn, Y., Yeo, J. W., Park, J. H., Lee, H. J., Ryu, J., Rhee, W. J., & Park, T. H. (2014) · Process Biochemistry · doi:10.1016/j.procbio.2014.05.008 · Cited by 17 · see citing works

Past, Present, and Future of Allergy in Korea

Kim, Y.-Y. (2010) · Allergy Asthma and Immunology Research · doi:10.4168/aair.2010.2.3.155 · Cited by 16 · see citing works

Optimization of formulation for enhanced intranasal delivery of insulin with translationally controlled tumor protein-derived protein transduction domain

Bae, H.-D., Lee, J.-S., Pyun, H., Kim, M., & Lee, K. (2019) · Drug Delivery · doi:10.1080/10717544.2019.1628119 · Cited by 16 · see citing works

Src‐type tyrosine kinase p56lck is critical for thymic stromal lymphopoietin‐induced allergic rhinitis

Nam, S., Kim, H., Han, N. ‐., Moon, P., Cho, J. ‐., Kim, H. ‐., & Jeong, H. (2018) · Clinical & Experimental Allergy · doi:10.1111/cea.13167 · Cited by 15 · see citing works

Cell-penetrating peptide-mediated delivery of therapeutic peptides/proteins to manage the diseases involving oxidative stress, inflammatory response and apoptosis

Sadeghian, I., Heidari, R., Raee, M. J., & Negahdaripour, M. (2022) · Journal of Pharmacy and Pharmacology · doi:10.1093/jpp/rgac038 · Cited by 14 · see citing works

Intranuclear interactomic inhibition of FoxP3 suppresses functions of Treg cells

Park, J., Ko, J. S., Shin, Y., Cho, J. Y., Oh, H.-A., Bothwell, A. L. M., & Lee, S. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.06.141 · Cited by 14 · see citing works

Cell-Permeable Peptide Blocks TLR4 Signaling and Improves Islet Allograft Survival

Dong, H., Zhang, Y., Song, L., Kim, D., Wu, H., Yang, L., Li, S., Morgan, K. A., Adams, D. B., & Wang, H. (2016) · Cell Transplantation · doi:10.3727/096368916x690449 · Cited by 13 · see citing works

Recombinant TAT-CD137 Ligand Cytoplasmic Domain Fusion Protein Induces the Production of IL-6 and TNF-α in Peritoneal Macrophages

Kim, J. D., Lee, E. A., Quang, N. N., Cho, H. R., & Kwon, B. (2011) · Immune Network · doi:10.4110/in.2011.11.4.216 · Cited by 12 · see citing works

A peptide interfering with the dimerization of oncogenic KITENIN protein and its stability suppresses colorectal tumour progression

Kim, S. J., Sun, E. G., Bae, J. A., Park, S., Hong, C., Park, Z., Kim, H., & Kim, K. K. (2022) · Clinical and Translational Medicine · doi:10.1002/ctm2.871 · Cited by 12 · see citing works

Functional polymorphism inCTLA4gene influences the response to therapy with inhaled corticosteroids in Slovenian children with atopic asthma

Berce, V., & Potočnik, U. (2009) · Biomarkers · doi:10.3109/13547500903384318 · Cited by 12 · see citing works

Galla Chinensis Attenuates Cigarette Smoke‐associated Lung Injury by Inhibiting Recruitment of Inflammatory Cells into the Lung

Lee, H., Yu, S., Lim, D., Lee, H., Jin, E., Jang, Y., & Kim, J. (2014) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.12308 · Cited by 11 · see citing works

CAR-NKT Cells in Asthma: Use of NKT as a Promising Cell for CAR Therapy

Taheri, M. M., Javan, F., Poudineh, M., & Athari, S. S. (2024) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-024-08998-0 · Cited by 11 · see citing works

Six-cell penetrating peptide-based fusion proteins for siRNA delivery

Li, H., & Tsui, T. (2014) · Drug Delivery · doi:10.3109/10717544.2014.881439 · Cited by 11 · see citing works

Insight of immune checkpoint inhibitor related myocarditis

Pi, J.-K., Chen, X.-T., Zhang, Y., Chen, X.-M., Wang, Y.-C., Xu, J., Zhou, J.-H., Yu, S.-S., & Wu, S. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.113559 · Cited by 10 · see citing works

Cell-Penetrating Function of the Poly(ADP-Ribose) (PAR)-Binding Motif Derived from the PAR-Dependent E3 Ubiquitin Ligase Iduna

Koo, J., Yoon, H., Kim, W., Cha, D., & Choi, J. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19030779 · Cited by 10 · see citing works

LDP12, a novel cell-permeable peptide derived from L1 capsid protein of the human papillomavirus

Lee, J. E., & Lim, H. J. (2011) · Molecular Biology Reports · doi:10.1007/s11033-011-0834-y · Cited by 10 · see citing works

PAG/Cbp suppression reveals a contribution of CTLA-4 to setting the activation threshold in T cells

Šmída, M., Cammann, C., Gurbiel, S., Kerstin, N., Lingel, H., Lindquist, S., Simeoni, L., Brunner-Weinzierl, M. C., Suchánek, M., Schraven, B. L., et al. (2013) · Cell Communication and Signaling · doi:10.1186/1478-811x-11-28 · Cited by 10 · see citing works

Attenuation of contact hypersensitivity by cell‐permeable heat shock protein 70 in BALB /c mouse model

Park, J. M., Je, J. H., Wu, W. H., Jee, H. J., Lee, S., & Lee, M. (2012) · Experimental Dermatology · doi:10.1111/exd.12044 · Cited by 9 · see citing works

dNP2-ctCTLA-4 inhibits German cockroach extract-induced allergic airway inflammation and hyper-responsiveness via inhibition of Th2 responses

Lim, S., Sohn, J.-H., Koo, J., Park, J., & Choi, J. (2017) · Experimental & Molecular Medicine · doi:10.1038/emm.2017.107 · Cited by 9 · see citing works

A non-catalytic role of IPMK is required for PLCγ1 activation in T cell receptor signaling by stabilizing the PLCγ1-Sam68 complex

Hong, S.-H., Kim, K., Shim, Y., Park, J., Choi, S. E., Min, H., Lee, S., Song, J., Kang, S., Jeong, W., et al. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-024-01907-0 · Cited by 8 · see citing works

Impaired cell adhesion, apoptosis, and signaling in WASP gene-disrupted Nalm-6 pre-B cells and recovery of cell adhesion using a transducible form of WASp

Sato, R., Iiizumi, S., Kim, E. S., Honda, F., Lee, S., Adachi, N., Koyama, H., Mizutani, S., & Morio, T. (2012) · International Journal of Hematology · doi:10.1007/s12185-012-1013-1 · Cited by 8 · see citing works

Rutin ameliorates cigarette smoke mediated lung inflammation in a mouse model of chronic obstructive pulmonary disease via regulating the levels of tumor necrosis factor-α, interleukin-8 and PAF

Chen, J., Su, J., Dong, L., Bai, Z., Liu, Y., Bao, H., Lu, Y., & Wu, Y. (2020) · Archives of Medical Science · doi:10.5114/aoms.2020.95874 · Cited by 8 · see citing works

dNP2-ctCTLA-4 inhibits German cockroach extract-induced allergic airway inflammation and hyper-responsiveness via inhibition of Th2 responses

Lim, S., Sohn, J.-H., Koo, J., Park, J., & Choi, J. (2017) · Experimental & Molecular Medicine · doi:10.1038/emm.2017.107 · Cited by 9 · see citing works

천식 마우스모델에서 Human Cytotoxic T Lymphocyte-associated Antigen 4-immunoglobulin (Hu.CTLA4-Ig) 융합단백의 기도 염증과 기도과민성 억제

장성옥, 김병주, 유진호, 송영화, 강미진, 최원아, 정현돈, 이소연, & 홍수종 (2008) · 천식 및 알레르기

CTLA4‐Ig inhibits allergic airway inflammation by a novel CD28‐independent, nitric oxide synthase‐dependent mechanism

Deppong, C. M., Parulekar, A. D., Boomer, J. S., Bricker, T. L., & Green, J. M. (2010) · European Journal of Immunology · doi:10.1002/eji.200940282 · Cited by 17 · see citing works

Cytotoxic T lymphocyte antigen 4 immunoglobulin modified dendritic cells attenuate allergic airway inflammation and hyperresponsiveness by regulating the development of T helper type 1 (Th1)/Th2 and Th2/regulatory T cell subsets in a murine model of asthma

Ying, L., Fu, Z., Luo, J., Zhou, C., Chen, Y., Wang, L., & Liu, E. (2011) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2011.04405.x · Cited by 22 · see citing works

Transduction of the cytoplasmic domain of CTLA-4 inhibits TcR-specific activation signals and prevents collagen-induced arthritis

Choi, J., Kim, S., Shin, J.-H., Gibson, T. F., Yoon, B.-S., Lee, D., Lee, S.-K., Bothwell, A. L. M., Lim, J.-S., & Lee, S. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0805198105 · Cited by 41 · see citing works