Noninvasive detection of macrophages using a nanoparticulate contrast agent for computed tomography

Hyafil, Fabien, Cornily, Jean-Christophe, Feig, Jonathan E, Gordon, Ronald, Vucic, Esad, Amirbekian, Vardan, Fisher, Edward A, Fuster, Valentin +2 more·2007·Nature Medicine
DOI 10.1038/nm1571

Cited by (467)

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  11. In vivo molecular imaging of vascular stress
    Marius C. Wick, Christian Kremser, Stefan Frischauf, Georg Wick · 2008 · Cell Stress and Chaperones
  12. Prediction of cardiovascular outcomes by imaging coronary atherosclerosis
    Faraz K. Pathan, Kazuaki Negishi · 2016 · Cardiovascular Diagnosis and Therapy
  13. Imaging outcomes in cardiovascular clinical trials
    Louai Razzouk, Michael E. Farkouh · 2009 · Nature Reviews Cardiology
  14. Design of catheter for combined intravascular photoacoustic and ultrasound imaging
    Bo Wang, Andrei B. Karpiouk, Stanislav Emelianov · 2008 · Proceedings/Proceedings - IEEE Ultrasonics Symposium
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    Carlos Navarrete-León, Adam Doherty, Margarita Štrimaite, Joseph C. Bear, Alessandro Olivo, Marco Endrizzi, Peter Stephen Patrick · 2024 · Nano Letters
  16. Dual-modality fiber-based OCT-TPL imaging system for simultaneous microstructural and molecular analysis of atherosclerotic plaques
    Tianyi Wang, Austin McElroy, David L. Halaney, Deborah C. Vela, Edmund Fung, Shafat Hossain, Jennifer E. Phipps, Bingqing Wang, Biwei Yin, Marc D. Feldman et al. · 2015 · Biomedical Optics Express
  17. Multimodality Imaging of Atherosclerosis (Magnetic Resonance Imaging/Computed Tomography/Positron Emission Tomography-Computed Tomography)
    James H F Rudd, Kelly S. Myers, Javier Sanz, Zahi Adel Fayad · 2007 · Topics in Magnetic Resonance Imaging
  18. Current imaging modalities for atherosclerosis
    Yu Kataoka, Kiyoko Uno, Rishi Puri, Stephen James Nicholls · 2012 · Expert Review of Cardiovascular Therapy
  19. X-ray intravital microscopy for functional imaging in rat hearts using synchrotron radiation coronary microangiography
    Keiji Umetani, Kazuhito Fukushima · 2013 · Review of Scientific Instruments
  20. Synthesis and characterization of ethosomal contrast agents containing iodine for computed tomography (CT) imaging applications
    Hanjin Shin, Young-Min Cho, Kangtaek Lee, Chang‐Ha Lee, Byoung Wook Choi, Bumsang Kim · 2013 · Journal of Liposome Research
  21. Delayed Plaque Enhancement by CT Angiography
    Shinichiro Fujimoto, Takeshi Kondo, Takahide Kodama, Shinichi Takase, Jagat Narula · 2012 · JACC. Cardiovascular imaging
  22. Pathobiology and Mechanisms of Atherosclerosis
    Thibaut Quillard, Kevin Croce · 2014 · Springer eBooks
  23. Molecular Imaging of the Heart
    Nabil E. Boutagy, Attila Fehér, Imran Alkhalil, Nsini Umoh, Albert J. Sinusas · 2019 · Comprehensive physiology
  24. Ischemic stroke nanomedicine
    Lan Luo, Meiqi Chang, Ying Wang, Yu Chen, Bingcang Huang · 2025 · Biomaterials
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    Isha Sharma, Shivani Bhardwaj, Ritu Karwasra, Dhirender Kaushik, Shivkant Sharma · 2023 · Recent Patents on Nanotechnology
  26. Nanotechnology at the forefront of liver cancer diagnosis
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    Stephen James Nicholls, Jordan Andrews, Rishi Puri, Kiyoko Uno, Yu Kataoka · 2012 · Circulation Journal
  29. Nanotechnology
    Avinash P. Ingle, Patrycja Golińska, Alka Yadav, Mehdi Razzaghi‐Abyaneh, Mrunali Rashmin Patel, Rashmin B. Patel, Yulia Victorovna Plekhanova, Anatoly Nikolaevich Reshetilov, Mahendra Rai · 2020 · Wiley eBooks
  30. Nanomedicine: Dynamic Integration of Nanotechnology with Biomedical Science
    Ki‐Bum Lee, Aniruddh Solanki, J. Dongun Kim, Jongjin Jung · 2010 · Pan Stanford Publishing eBooks
  31. Recent Advances in Visualizing Vulnerable Plaque: Focus on Noninvasive Molecular Imaging
    Gezim Bala, Bernard Cosyns · 2014 · Current Cardiology Reports
  32. The Significance of Nanoparticles in Medicine and Their Potential Application in Asthma
    Stephanie M. Tortorella, Tom C. Karagiannis · 2014 · Springer eBooks
  33. Novel clinical applications of state-of-the-art multi-slice computed tomography
    Joanne Désirée Schuijf, Victoria Delgado, Jacob M. van Werkhoven, Fleur Rianne de Graaf, Joella E. van Velzen, Mark M. Boogers, Lucia J.M. Kroft, A. Roos, J. Wouter Jukema, Johannes H. C. Reiber et al. · 2009 · International journal of cardiac imaging
  34. Assessing vulnerable plaque: Is shear stress enough?
    Dimitris Tousoulis, Νικόλαος Παπαγεωργίου, Andreas G. Synetos, Christodoulos Stefanadis · 2014 · International Journal of Cardiology
  35. Atherosclerosis: cell biology and lipoproteins – new developments in imaging of inflammation of the vulnerable plaque
    Nicholas Foin, Paul Charles Evans, Rob Krams · 2008 · Current Opinion in Lipidology
  36. Size and CT density of iodine‐containing ethosomal vesicles obtained by membrane extrusion: Potential for use as CT contrast agents
    Na Bomin, Byoung Wook Choi, Bumsang Kim · 2013 · Biotechnology Journal
  37. Approaching the Asymptote: Obstacles and Opportunities for Nanomedicine in Cardiovascular Disease
    Sascha N. Goonewardena · 2012 · Current Atherosclerosis Reports
  38. Scintillating Balloon-Enabled Fiber-Optic System for Radionuclide Imaging of Atherosclerotic Plaques
    Raiyan T. Zaman, Hisanori Kosuge, Colin M. Carpenter, Conroy Sun, Michael V. McConnell, Lei Xing · 2015 · Journal of Nuclear Medicine
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    Johan G. Schnitzler, Kim E. Dzobo, Nick S. Nurmohamed, Erik S.G. Stroes, Jeffrey Kroon · 2020 · Atherosclerosis
  40. Advances in contrast media for vascular imaging of atherosclerosis
    Victoria E. L. Young, Andrew Joseph Degnan, Jonathan H. Gillard · 2011 · Imaging in Medicine
  41. High sensitivity intravascular photoacoustic imaging of macrophages
    Bo Wang, Evgeniya Yantsen, Konstantin Sokolov, Stanislav Emelianov · 2009 · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
  42. Nanoparticles for Cardiovascular Imaging with CT
    Peter Chhour, Rabee Cheheltani, Pratap C. Naha, Harold I Litt, Victor A. Ferrari, David P. Cormode · 2016 · Springer eBooks
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    Noel M. Caplice, Kenneth Martin · 2010 · JACC. Cardiovascular imaging
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    Yongwen Zhou, Tong Yue, Yu Ding, Huiling Tan, Jianping Weng, Sihui Luo, Xueying Zheng · 2023 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
  46. The vulnerable plaque: Current concepts and future perspectives on coronary morphology, composition and wall stress imaging
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    James Nadel, Xiaoying Wang, Prakash Saha, André Bongers, Sergey Tumanov, Nicola Giannotti, Weiyu Chen, Niv Vigder, Mohammed M. Chowdhury, Gastao José Lima da Cruz et al. · 2024 · European Heart Journal - Imaging Methods and Practice
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    Marlon Perera, Joseph J. Ischia, Damien Michael Bolton, Arthur Shulkes, Graham S. Baldwin, Oneel Patel · 2020 · Journal of Nephropathology
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  55. Ultrasmall, elementary and highly translational nanoparticle X-ray contrast media from amphiphilic iodinated statistical copolymers
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  56. Conduction nerveuse d’excitation sans potentiel d’action
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    Ravi K. Sureddi, Jawahar L. Mehta · 2011 · Journal of Nanotechnology in Engineering and Medicine
  59. Molecular Imaging of Atherosclerosis
    Dong‐Eog Kim, Sang‐Wuk Jeong · 2009 · Journal of Korean Medical Association
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    Sara Seitun, Erica Maffei, Chiara Martini, Margherita Castiglione Morelli, Anselmo Alessandro Palumbo, Filippo Cademartiri · 2012 · Springer eBooks
  61. Nanosized drug delivery systems as radiopharmaceuticals
    Mine Silindir‐Gunay, A. Yekta Özer · 2017 · Elsevier eBooks
  62. How do you quantify noncalcified plaque?
    Joanne Désirée Schuijf, Jeroen Joost Bax · 2008 · Journal of cardiovascular computed tomography
  63. Spectral Micro-CT Imaging of Ex Vivo Atherosclerotic Plaque
    Rafidah Zainon · 2012 · UC Research Repository (University of Canterbury)
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    Minghuan Mao, Banghua Zhong, Zhifei Jing, Qi Pan, Ning Liu, Yijie Zhang · 2025 · Industrial Crops and Products
  65. The relationship between plaque imaging characterization and treatment modality selection
    Florian Schwarz, Marcus Treitl, J Grimm, Clemens C. Cyran, Konstantin Nikolaou, Maximilian Ferdinand Reiser, Tobias Saam · 2011 · Interventional Cardiology
  66. Theranostic Toolbox for Neutrophil Functionalization
    Pascal Bouvain, Kay‐Matthias Thomy, Anika Prinz, Bodo Steckel, Shiwa Kadir, Alexandra Röhs, Jonas Schmitz, Claudia Dohle, Matthias Karg, Maria Grandoch et al. · 2025 · Advanced Science
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    Raiyan T. Zaman, Siavash Yousefi, Hidetoshi Chibana, Fumiaki Ikeno, Steven Long, Sanjiv Sam Gambhir, Frederick T. Chin, Michael V. McConnell, Lei Xing, Alan C. Yeung · 2019 · Journal of Nuclear Medicine
  68. Atherosclerosis and Angiogenesis: Double Face of Neovascularization in Atherosclerotic Intima and Collateral Vessels in Ischemic Organs
    Katsuo Sueishi, Mitsuho Onimaru, Yutaka Nakashima · 2009 · Springer eBooks
  69. Molecular Imaging of Atherosclerosis
    Ahmed A Tawakol, Jagat Narula, Jagat Narula, Jagat Narula, Jagat Narula, Farouc Amin Jaffer · 2012 · Springer eBooks
  70. Fullerenes and Their Potential in Nanomedicine
    Ajit D. Kelkar, Daniel J. C. Herr, James G. Ryan · 2014 · CRC Press eBooks
  71. Development of biocompatible nanocubes as a T 1 -contrast enhancer for MR imaging of primary and metastatic liver cancer
    Xiaoxia Song, Xianzhu Xu, Hongping Wan, Qun Tang · 2014 · RSC Advances
  72. Visualización de la guerra macrofágica arterial con resonancia magnética nuclear, tomografía de emisión de positrones y tomografía computarizada
    Valentı́n Fuster, Javier Sanz · 2009 · Revista Española de Cardiología
  73. Advances in imaging vascular inflammation
    Nikil K Rajani, Francis Richard Joshi, Jason M. Tarkin, James H F Rudd · 2013 · Clinical and Translational Imaging
  74. Imaging of vascular biology in the heart
    Sina Tavakoli, Mehran M. Sadeghi · 2009 · Current Cardiovascular Imaging Reports
  75. Macrophage Tracking Using the Hungarian Algorithm in Time Lapse MR Images
    Tashita Atsuki, Syoji Kobashi, Yuki Mori, Masakazu Morimoto, Satoru Aikawa, Yoshichika Yoshioka, Yutaka Hata · 2015 · International Conference on Emerging Trends in Engineering and Technology (ICETET)
  76. Nanoparticle Contrast Agents for Cardiovascular Medical Imaging
    David P. Cormode, Ahmed Klink, Zahi Adel Fayad, Willem J. M. Mulder · 2011 · Science Publishers eBooks
  77. Current Clinical Status of Vascular Non-Invasive Imaging Methodologies
    Thanjavur Bragadeesh, Ann C. Tweddel · 2011 · Advances in bioinformatics and biomedical engineering book series
  78. Biomedical Applications of Functional Micro-/Nanoimaging Probes
    Fangfang Yu, Shunlong Xu, Xianwei Ni, Jinmin Ye, Yueyue Cheng, Pengfei Wang, Beibei Wu, Chengfang Wang, Yanyan Dong, Liping Wang et al. · 2018 · Engineering materials
  79. Molecular Imaging Methods in Theranostic Platform
    Fuad Nurili, Gülin Uçmak Vural, Ömer Aras · 2015 · Nuclear Medicine Seminars
  80. Nanotechnology for Molecular Imaging of Atherosclerosis: Current Design and Approaches
    Mardhiah Maslizan, Intan Diana Mat Azmi, Adila Mohamad Jaafar, Muhammad Salahuddin Haris · 2021 · Journal of Advanced Research in Fluid Mechanics and Thermal Sciences
  81. Cardiovascular Molecular Imaging
    Alan Morrison, Joseph C. Wu, Mehran M. Sadeghi · 2015 · Oxford University Press eBooks
  82. [Coronary artery disease and cardiac ischemic disease: two different pathologies with different diagnostic procedures].
    Enrique Vallejo · 2009 · PubMed
  83. Multislice Computed Tomography in Acute Coronary Syndromes
    Pim J. de Feyter, Koen Nieman · 2011 · Elsevier eBooks
  84. Atherosclerosis
    Christopher D. Owens, Michael S. Conte · 2010 · Elsevier eBooks
  85. The imaging of acute chest pain with multidetector computed tomography
    M R JONES · 2009 · Imaging
  86. Vascular Biology
    Cristina Sanina, Olga L. Bockeria, Karlo A. Wiley, Jonathan E. Feig · 2018 · Wiley eBooks
  87. Imaging of Tumor-Associated Macrophages
    Nastaran Khalili, Nima Rezaei · 2025 · Springer eBooks
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    Yitong Zhao, Mengjun Wang, Ming Ma, Yu Zhang, Haoan Wu · 2025 · Small Structures
  89. Imaging Occlusive Atherosclerosis
    José Fernandes e Fernandes, Luís Mendes Pedro, Ruy Fernandes e Fernandes, Luís Silvestre · 2013 · Springer eBooks
  90. Macrophage learning-tracking algorithm in time-lapse MR images
    Tashita Atsuki, Syoji Kobashi, Manabu Nii, Yuki Mori, Yoshichika Yoshioka, Yutaka Hata · 2016 · International Conference on Machine Learning and Cybernetics
  91. Development and validation of an activatable PET radiotracer reporting extracellular myeloperoxidase activity for the detection of unstable atherosclerotic plaque
    George P. Keeling, Xiaoying Wang, Weiyu Chen, Nadia Chaher, Ling Gao, Marcelo E. Andía, Sergey Tumanov, Piotr GOLDA, Mohammed M. Chowdhury, Prakash Saha et al. · 2026 · npj Imaging
  92. Nanomedicine for Treatment of Cardiovascular Diseases and Stroke
    Narenda Kumar, Rajiv Kumar · 2014 · Elsevier eBooks
  93. Molecular MRI of Atherosclerosis
    B.C. Te, Klaas Nicolay · 2012 · InTech eBooks
  94. Plaque Evaluation by Coronary CT Angiography
    Shinichiro Fujimoto, Takeshi Kondo, Hiroyuki Daida · 2014 · Journal of the Japanese Coronary Association
  95. Image alignment for single-cell imaging of macrophage in the mouse brain using 11.7T MRI
    Syoji Kobashi, Yuki Mori, Yoshichika Yoshioka, Yutaka Hata · 2014 · World Automation Congress (WAC)
  96. Imaging coronary atherosclerosis: is there space for magnetic resonance imaging?
    Jordan Andrews, Stephen James Nicholls · 2013 · Expert Review of Cardiovascular Therapy
  97. State of the Art Cardiac MDCT: Where are We Today and Where Are We Going?
    Yasushi Koyama · 2008 · Japanese Journal of Radiological Technology
  98. Ethyl-3,5-bis(acetylamino)-2,4,6-triiodobenzoate nanoparticles
    Huiming Zhang · 2008 · Europe PMC (PubMed Central)
  99. Coronary Artery Calcification
    Shreenidhi M. Venuraju, Ajay Kumar Yerramasu, Dennis A. Goodman, Avijit Lahiri · 2010 · Elsevier eBooks
  100. High-Perform Yb-Based Nanoparticulate X-Ray CT Contrast Agent
    Yanlan Liu · 2017 · Springer theses