Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
Dong, Haidong, Strome, Scott E., Salomao, Diva R., Tamura, Hideto, Hirano, Fumiya, Flies, Dallas B., Roche, Patrick C., Lu, Jun +5 more·2002·Nature Medicine
DOI 10.1038/nm730
Cited by (1,026)
Items 501–600 of 1,026
- Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumabRichard S. Hotchkiss, Elizabeth Colston, Sachin P. Yende, Elliott D. Crouser, Greg S. Martin, Timothy E. Albertson, Raquel R. Bartz, Scott C. Brakenridge, Matthew J. Delano, Pauline K. Park et al. · 2019 · Intensive Care Medicine
- Targeting PD1–PDL1 immune checkpoint in plasmacytoid dendritic cell interactions with T cells, natural killer cells and multiple myeloma cellsArghya Ray, Deepika Sharma Das, Yan Y. Song, Paul Gerard Guy Richardson, Nikhil C. Munshi, Dharminder Chauhan, Kenneth Carl Anderson · 2015 · Leukemia
- Cancer stem cells and human malignant melanomaT. Schatton, M. Frank · 2007 · Pigment Cell & Melanoma Research
- Research Status and Outlook of PD-1/PD-L1 Inhibitors for Cancer TherapyLeilei Ai, Jian Chen, Hao Yan, Qiaojun He, Peihua Luo, Zhifei Xu, Xiaochun Yang · 2020 · Drug Design Development and Therapy
- FOXP3+ Tregs and B7-H1+/PD-1+T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapyHazem Ghebeh, Eman Barhoush, Asma M. Tulbah, Naser B. Elkum, Taher Al‐Tweigeri, Said Dermime · 2008 · BMC Cancer
- Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infectionPablo Penaloza‐MacMaster, Alice Oliffson Kamphorst, Andreas Wieland, Koichi Araki, Smita Swaminathan Iyer, Erin E. West, Leigh A. O’Mara, Shu Yang, Bogumila T. Konieczny, Arlene H. Sharpe et al. · 2014 · The Journal of Experimental Medicine
- Glioblastoma-Derived IL6 Induces Immunosuppressive Peripheral Myeloid Cell PD-L1 and Promotes Tumor GrowthJonathan Balquiedra Lamano, Jason Balquidera Lamano, Yuping D. Li, Joseph D. DiDomenico, Winward Choy, Dorina Veliceasa, Daniel Eduardo Oyon, Shayan Fakurnejad, Leonel Ampie, Kartik Kesavabhotla et al. · 2019 · Clinical Cancer Research
- B7-H1-Induced Apoptosis as a Mechanism of Immune Privilege of Corneal AllograftsHori, Junko, Wang, Mingcong, Miyashita, Megumi, Tanemoto, Keiko, Takahashi, Hiroshi, Takemori, Toshitada, Okumura, Ko, Yagita, Hideo, Azuma, Miyuki · 2006 · The Journal of Immunology
- Trastuzumab upregulates PD-L1 as a potential mechanism of trastuzumab resistance through engagement of immune effector cells and stimulation of IFNγ secretionBharat K. R. Chaganty, Songbo Qiu, Anneliese M. M. Gest, Yang Lü, Cristina Ivan, George A. Călin, Louis M. Weiner, Zhen Fan · 2018 · Cancer Letters
- PD-1 Blockade and OX40 Triggering Synergistically Protects against Tumor Growth in a Murine Model of Ovarian CancerZhiqiang Guo, Xin Wang, Dali Cheng, Zhijun Xia, Meng Luan, Shulan Zhang · 2014 · PLoS ONE
- Immune modulation of the tumor microenvironment for enhancing cancer immunotherapyChristel Devaud, Liza B. John, Jennifer A. Westwood, Phillip Kevin Darcy, Michael H. Kershaw · 2013 · OncoImmunology
- PDL1 Is Required for Peripheral Transplantation Tolerance and Protection from Chronic Allograft RejectionKatsunori Tanaka, Monica J. Albin, Xueli Yuan, Kazuhiro Yamaura, Antje Habicht, Takaya Murayama, Martin R. Grimm, Ana Maria Waaga, Takuya Ueno, Robert F. Padera et al. · 2007 · The Journal of Immunology
- Combinations of Bevacizumab With Cancer ImmunotherapyDaniel S. Chen, Herbert I. Hurwitz · 2018 · The Cancer Journal
- Combination immunotherapy with α-CTLA-4 and α-PD-L1 antibody blockade prevents immune escape and leads to complete control of metastatic osteosarcomaLussier, Danielle M, Johnson, John L, Hingorani, Pooja, Blattman, Joseph N · 2015 · Journal for ImmunoTherapy of Cancer
- Defining the optimal murine models to investigate immune checkpoint blockers and their combination with other immunotherapiesMiguel F. Sanmamed, Cariad Chester, Ignacio Melero, Holbrook E K Kohrt · 2016 · Annals of Oncology
- Specific TP53 subtype as biomarker for immune checkpoint inhibitors in lung adenocarcinomaHao Sun, Si‐Yang Maggie Liu, Jiaying Zhou, Jintian Xu, Huang-Kai Zhang, Hong‐Hong Yan, Jiaojiao Huan, Pingping Dai, Chong‐Rui Xu, Jian Su et al. · 2020 · EBioMedicine
- The Roles of the New Negative T Cell Costimulatory Pathways in Regulating AutoimmunitySamia Joseph Khoury, Mohamed H. Sayegh · 2004 · Immunity
- Focus on TILs: prognostic significance of tumor infiltrating lymphocytes in human melanoma.Darryl A. Oble, Robert P. Loewe, Ping Yu, Martín C. Mihm · 2009 · PubMed Central
- Restoring Immune Function of Tumor-Specific CD4+ T Cells during Recurrence of MelanomaStephen R. Goding, Kyle A. Wilson, Ying Xie, Kristina M. Harris, Aparna B. Baxi, Akgül Akpınarlı, Amy M. Fulton, Koji Tamada, Scott Eric Strome, Paul Andrew Antony · 2013 · The Journal of Immunology
- Neutrophils as active regulators of the immune system in the tumor microenvironmentMerav E. Shaul, Zvi Gregorio Fridlender · 2017 · Journal of Leukocyte Biology
- High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosisFabian Finkelmeier, Özge Canli, Andrea Oliver Tal, Thomas Pleli, Jörg Trojan, Michael Schmidt, Bernd Kronenberger, Stefan Zeuzem, Albrecht Piiper, Florian R. Greten et al. · 2016 · European Journal of Cancer
- Insights into the post-translational modification and its emerging role in shaping the tumor microenvironmentWen Li, Feifei Li, Xia Zhang, Hui‐Kuan Lin, Chuan Shan Xu · 2021 · Signal Transduction and Targeted Therapy
- Current state of anti-PD-L1 and anti-PD-1 agents in cancer therapyAbhisek Swaika, William A. Hammond, Richard Wayne Joseph · 2015 · Molecular Immunology
- Negative regulators of T‐cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infectionsTsvetelina Pentcheva‐Hoang, Emily Corse, James Patrick Allison · 2009 · Immunological Reviews
- T cell exhaustion: from pathophysiological basics to tumor immunotherapyKemal Catakovic, Eckhard Klieser, Daniel Neureiter, Roland Geisberger · 2017 · Cell Communication and Signaling
- Tumor immunotherapy resistance: Revealing the mechanism of PD-1 / PD-L1-mediated tumor immune escapeJiawen Cui, Yao Li, Yang Yang, Hai‐Kui Yang, Jia-Mei Dong, Zhi-Hua Xiao, Xin He, Jiahao Guo, Ruiqi L. Wang, Bo Dai et al. · 2024 · Biomedicine & Pharmacotherapy
- Interferon-γ and tumor necrosis factor-α induce an immunoinhibitory molecule, B7-H1, via nuclear factor-κB activation in blasts in myelodysplastic syndromesAsaka Kondo, Taishi Yamashita, Hideto Tamura, Wanhong Zhao, Takashi Tsuji, Masumi Shimizu, Eiji Shinya, Hidemi Takahashi, Koji Tamada, Lieping Chen et al. · 2010 · Blood
- Characterization of PD-L1 Expression and Associated T-cell Infiltrates in Metastatic Melanoma Samples from Variable Anatomic SitesHarriet M. Kluger, Christopher R. Zito, Meaghan L. Barr, Marina K. Baine, Veronica Chiang, Mario Sznol, David L. Rimm, Lieping Chen, Lucia B. Jilaveanu · 2015 · Clinical Cancer Research
- Nivolumab: Targeting PD-1 to Bolster Antitumor ImmunityJulie Renee Brahmer, Hans J. Hammers, Evan J. Lipson · 2015 · Future Oncology
- ATR kinase inhibitor AZD6738 potentiates CD8+ T cell-dependent antitumor activity following radiationVendetti, Frank P., Karukonda, Pooja, Clump, David A., Teo, Troy, Lalonde, Ronald, Nugent, Katriana, Ballew, Matthew, Kiesel, Brian F., Beumer, Jan H., Sarkar, Saumendra N. et al. · 2018 · Journal of Clinical Investigation
- Immunomodulators targeting the PD‐1/PD‐L1 protein‐protein interaction: From antibodies to small moleculesJeffrey Yang, Longqin Hu · 2018 · Medicinal Research Reviews
- TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate TumorigenesisDaniel R. Principe, Brian T. DeCant, Emman Mascariñas, Elizabeth A. Wayne, Andrew M. Diaz, Naomi Akagi, Rosa F. Hwang, Boris Pasche, David W. Dawson, Deyu Fang et al. · 2016 · Cancer Research
- Human Anti-tumor Immunity: Insights from Immunotherapy Clinical TrialsJackson G. Egen, Wenjun Ouyang, Lawren C. Wu · 2020 · Immunity
- <i>TP53</i>
mutations in myelodysplastic syndromes and secondary AML confer an immunosuppressive phenotypeSallman, David A., McLemore, Amy F., Aldrich, Amy L., Komrokji, Rami S., McGraw, Kathy L., Dhawan, Abhishek, Geyer, Susan, Hou, Hsin-An, Eksioglu, Erika A., Sullivan, Amy et al. · 2020 · Blood
- The role of herpesvirus entry mediator as a negative regulator of T cell–mediated responsesYang Wang, Sumit Kumar Subudhi, Robert A. Anders, James C. Lo, Yonglian Sun, Sarah E. Blink, Yugang Wang, Jing Hong Wang, Xiaojuan Liu, Karin Mink et al. · 2005 · Journal of Clinical Investigation
- Mesenchymal stem cells repress Th17 molecular program through the PD-1 pathwayLuz-Crawford, Patricia, Noël, Danièle, Fernandez, Ximena, Khoury, Maroun, Figueroa, Fernando, Carrión, Flavio, Jorgensen, Christian, Djouad, Farida · 2012 · PLoS ONE
- Programmed Cell Death Ligand 1 Expression in OsteosarcomaJacson K. Shen, Gregory Michael Cote, Edwin Choy, Pei Yang, David C. Harmon, Joseph Hasbrouck Schwab, G. Petur Nielsen, Ivan A. Chebib, Soldano Ferrone, Xinhui Wang et al. · 2014 · Cancer Immunology Research
- The role of PD-L1 in the radiation response and clinical outcome for bladder cancerChun‐Te Wu, Wen‐Cheng Chen, Ying‐Hsu Chang, Wei‐Yu Lin, Miao‐Fen Chen · 2016 · Scientific Reports
- Immune Resistance in Lung AdenocarcinomaΜάγδα Σπέλλα, Georgios T. Stathopoulos · 2021 · Cancers
- A comprehensive review of immune checkpoint inhibitors for cancer treatmentMd Aslam Hossain · 2024 · International Immunopharmacology
- B7 Family Molecules Are Favorably Positioned at the Human Maternal-Fetal Interface1Margaret Greene Petroff, Lieping Chen, Teresa A. Phillips, Dagmar Azzola, Peter Sedlmayr, Joan S. Hunt · 2003 · Biology of Reproduction
- High-Resolution PET Imaging with Therapeutic Antibody-based PD-1/PD-L1 Checkpoint TracersMichael Hettich, Friederike Braun, Mark Daniel Bartholomä, Reinhold Schirmbeck, Gabriele Niedermann · 2016 · Theranostics
- Future prospects of immune checkpoint blockade in cancer: from response prediction to overcoming resistanceYoung‐Jun Park, Da‐Sol Kuen, Yeonseok Chung · 2018 · Experimental & Molecular Medicine
- LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapyGaopeng Li, Ilona Kryczek, Jutaek Nam, Xiong Li, Shasha Li, Jing Li, Shuang Wei, Sara Grove, Linda Vatan, Jiajia Zhou et al. · 2021 · Nature Cell Biology
- Combination therapy strategies for improving PD‐1 blockade efficacy: a new era in cancer immunotherapyPartha Sarathi Chowdhury, Kenji Chamoto, Tasuku Honjo · 2017 · Journal of Internal Medicine
- Targeting Wnt/β-Catenin Signaling for Cancer ImmunotherapyBojun Wang, Tian Tian, Karl‐Henning Kalland, Xisong Ke, Yi Qu · 2018 · Trends in Pharmacological Sciences
- GOLM1 exacerbates CD8+ T cell suppression in hepatocellular carcinoma by promoting exosomal PD-L1 transport into tumor-associated macrophagesJinhong Chen, Zhifei Lin, Lu Liu, Rui Zhang, Yan Geng, Ming-Hao Fan, Wenwei Zhu, Ming Lü, Lu Lu, Huliang Jia et al. · 2021 · Signal Transduction and Targeted Therapy
- Soluble CD276 (B7‐H3) is released from monocytes, dendritic cells and activated T cells and is detectable in normal human serumGuangbo Zhang, Jianquan Hou, Jinfang Shi, Gehua Yu, Binfeng Lu, Xueguang Zhang · 2008 · Immunology
- Dual blockade of CXCL12‐CXCR4 and PD‐1–PD‐L1 pathways prolongs survival of ovarian tumor–bearing mice by prevention of immunosuppression in the tumor microenvironmentYang C. Zeng, Binghao Li, Yingying Liang, Patrick M. Reeves, Xiying Qu, Chongzhao Ran, Qiuyan Liu, Michael V. Callahan, Ann E. Sluder, Jeffrey A. Gelfand et al. · 2019 · The FASEB Journal
- Anti–Programmed Death-1 Synergizes with Granulocyte Macrophage Colony-Stimulating Factor–Secreting Tumor Cell Immunotherapy Providing Therapeutic Benefit to Mice with Established TumorsBetty Li, Melinda J. VanRoey, Changyu Wang, Tseng-hui Timothy Chen, Alan J. Korman, Karin U. Jooss · 2009 · Clinical Cancer Research
- Intratumoral expression of IL-7 and IL-12 using an oncolytic virus increases systemic sensitivity to immune checkpoint blockadeShinsuke Nakao, Yukinori Arai, Mamoru Tasaki, Midori YAMASHITA, Ryuji Murakami, Tatsuya Kawase, Nobuaki Amino, Motomu Nakatake, Hajime Kurosaki, Masamichi Mori et al. · 2020 · Science Translational Medicine
- Attenuation of peripheral serotonin inhibits tumor growth and enhances immune checkpoint blockade therapy in murine tumor modelsMarcel André Schneider, Laura Heeb, Michał Beffinger, Stanislav Pantelyushin, Michael Linecker, Lilian Roth, Kuno Lehmann, U. Ungethüm, Sebastian Kobold, Rolf Graf et al. · 2021 · Science Translational Medicine
- Development of an automated PD-L1 immunohistochemistry (IHC) assay for non-small cell lung cancerPhillips, Therese, Simmons, Pauline, Inzunza, Hector D., Cogswell, John, Novotny, James, Taylor, Clive, Zhang, Xiaoling · 2015 · Applied Immunohistochemistry & Molecular Morphology
- Exploiting CTLA-4, PD-1 and PD-L1 to reactivate the host immune response against cancerSergio A. Quezada, Karl S. Peggs · 2013 · British Journal of Cancer
- Epigenetics and immunotherapy: The current state of playJennifer Dunn, Sudha Rao · 2017 · Molecular Immunology
- Defining and Understanding Adaptive Resistance in Cancer ImmunotherapyTae Kon Kim, Roy S. Herbst, Lieping Chen · 2018 · Trends in Immunology
- Hypomethylation and up-regulation ofPD-1in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylationAndreas Due Ørskov, Marianne Bach Treppendahl, Anni Skovbo, Mette Skov Holm, Lone Smidstrup Friis, Marianne Hokland, Kirsten Grønbæk · 2015 · Oncotarget
- Combination Therapy With Reovirus and Anti-PD-1 Blockade Controls Tumor Growth Through Innate and Adaptive Immune ResponsesKarishma R. Rajani, Christopher Parrish, Timothy J. Kottke, Jill Thompson, Shane Zaidi, Elizabeth J. Ilett, Kevin G. Shim, Rosa María Díaz, Hardev Pandha, Kevin Joseph Harrington et al. · 2015 · Molecular Therapy
- The role of B7 family molecules in hematologic malignancyPaul Greaves, John G. Gribben · 2012 · Blood
- The New B7s: Playing a Pivotal Role in Tumor ImmunityDallas B. Flies, Lieping Chen · 2007 · Journal of Immunotherapy
- Costimulating aberrant T cell responses by B7-H1 autoantibodies in rheumatoid arthritisHaidong Dong, Scott Eric Strome, Eric L. Matteson, Kevin G. Moder, Dallas B. Flies, Gefeng Zhu, Hideto Tamura, Colin L. W. Driscoll, Lieping Chen · 2003 · Journal of Clinical Investigation
- Paucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistanceAllison M. Martin, Thomas R. Nirschl, Christopher J. Nirschl, Brian J. Francica, Christina M. Kochel, Adrie van Bokhoven, Alan Keith Meeker, Marshall Scott Lucia, Robert A. Anders, A M DeMarzo et al. · 2015 · Prostate Cancer and Prostatic Diseases
- Radiation therapy and PD-1/PD-L1 blockade: the clinical development of an evolving anticancer combinationJun Gong, Thang Q. Le, Erminia Massarelli, Andrew Eugene Hendifar, Richard Tuli · 2018 · Journal for ImmunoTherapy of Cancer
- Oscillating CD8+ T Cell Effector Functions after Antigen Recognition in the LiverIsogawa, Masanori, Furuichi, Yoshihiro, Chisari, Francis V. · 2005 · Immunity
- Tumor PD-L1 co-stimulates primary human CD8+ cytotoxic T cells modified to express a PD1:CD28 chimeric receptorMegan E. Prosser, Christine E. Brown, Andrew F. Shami, Stephen J. Forman, Michael C. Jensen · 2012 · Molecular Immunology
- The HIF-1α Hypoxia Response in Tumor-Infiltrating T Lymphocytes Induces Functional CD137 (4-1BB) for ImmunotherapyAsís Palazón, Iván Martínez‐Forero, Álvaro Teijeira, Aizea Morales‐Kastresana, Carlos Alfaro, Miguel F. Sanmamed, José Luis Perez‐Gracia, Iván Peñuelas, Sandra Hervás‐Stubbs, Ana Rouzaut et al. · 2012 · Cancer Discovery
- Autophagy inhibition enhances PD-L1 expression in gastric cancerXiaojuan Wang, William Ka Kei Wu, Jing Gao, Zhongwu Li, Bin Dong, Xiaoting Lin, Yilin Li, Yanyan Li, Jifang Gong, Changsong Qi et al. · 2019 · Journal of Experimental & Clinical Cancer Research
- Role of the Programmed Death-1 Pathway in Regulation of Alloimmune Responses In VivoSigrid E. Sandner, Michael R. Clarkson, Alan David Salama, Alberto Sanchez Fueyo, Christoph M. Domenig, Antje Habicht, Nader Najafian, Hideo Yagita∥, Miyuki Azuma, Laurence A. Turka et al. · 2005 · The Journal of Immunology
- Insights from a 30-year journey: function, regulation and therapeutic modulation of PD1Chamoto, Kenji, Yaguchi, Tomonori, Tajima, Masaki, Honjo, Tasuku · 2023 · Nature Reviews Immunology
- Schistosoma mansoni Worms Induce Anergy of T Cells via Selective Up-Regulation of Programmed Death Ligand 1 on MacrophagesPhilip Smith, Caitríona M. Walsh, Niamh E. Mangan, Rosie E. Fallon, Jon R. Sayers, Andrew N. J. McKenzie, Padraic G. Fallon · 2004 · The Journal of Immunology
- Lymphocyte‐activation gene‐3, an important immune checkpoint in cancerYayi He, Christopher J. Rivard, Leslie M. Rozeboom, Hui Yu, Kim E. Ellison, Ashley A. Kowalewski, Caicun Zhou, Fred R. Hirsch · 2016 · Cancer Science
- Endoplasmic reticulum stress‐induced exosomal miR‐27a‐3p promotes immune escape in breast cancer via regulating PD‐L1 expression in macrophagesXiaoli Yao, Yi Tu, Yulin Xu, Yueyue Guo, Feng Yao, Xinghua Zhang · 2020 · Journal of Cellular and Molecular Medicine
- PD-1 expression on dendritic cells suppresses CD8<sup>+</sup>T cell function and antitumor immunityLim, Tong Seng, Chew, Valerie, Sieow, Je Lin, Goh, Siting, Yeong, Joe Poh-Sheng, Soon, Ai Ling, Ricciardi-Castagnoli, Paola · 2016 · OncoImmunology
- Hypomethylating agents in combination with immune checkpoint inhibitors in acute myeloid leukemia and myelodysplastic syndromesNaval Guastad Daver, Prajwal Chaitanya Boddu, Guillermo Garcia‐Manero, Shalini Singh Yadav, Padmanee Sharma, James Patrick Allison, Hagop M. Kantarjian · 2018 · Leukemia
- Platelet Adhesion and Degranulation Induce Pro-Survival and Pro-Angiogenic Signalling in Ovarian Cancer CellsKarl Egan, Darragh Crowley, Paul C Smyth, Sharon A. O’Toole, Cathy D. Spillane, Cara M. Martin, Michael F. Gallagher, Aoife Canney, Lucy Norris, Niamh Conlon et al. · 2011 · PLoS ONE
- Upregulation of programmed cell death ligand 1 promotes resistance response in non‐small‐cell lung cancer patients treated with neo‐adjuvant chemotherapyPanpan Zhang, Yuanyuan Ma, Chao Lv, Miao Huang, Mingzhen Li, Bin Dong, Xijuan Liu, Guo An, Wenlong Zhang, Jianzhi Zhang et al. · 2016 · Cancer Science
- PI(3) kinase is associated with a mechanism of immunoresistance in breast and prostate cancerCrane, C A, Panner, A, Murray, J C, Wilson, S P, Xu, H, Chen, L, Simko, J P, Waldman, F M, Pieper, R O, Parsa, A T · 2009 · Oncogene
- Expression of B7-H1 on Gastric Epithelial Cells: Its Potential Role in Regulating T Cells during Helicobacter pylori InfectionSoumita Das, Giovanni Suárez, Ellen J. Beswick, Johanna C. Sierra, David Yates Graham, Victor E. Reyes · 2006 · The Journal of Immunology
- Immunomodulation by ionizing radiation—impact for design of radio‐immunotherapies and for treatment of inflammatory diseasesBenjamin Frey, Michael Rückert, Lisa Deloch, Paul F. Rühle, Anja Derer, Rainer Fietkau, Udo S. Gaipl · 2017 · Immunological Reviews
- Checkpoint Blockade Reverses Anergy in IL-13Rα2 Humanized scFv-Based CAR T Cells to Treat Murine and Canine GliomasYibo Yin, Alina C. Boesteanu, Zev A. Binder, Chong Bing Xu, Reiss A. Reid, Jesse L. Rodriguez, Danielle R. Cook, Radhika Thokala, Kristin Blouch, Bevin McGettigan-Croce et al. · 2018 · Molecular Therapy — Oncolytics
- A novel bifunctional anti-PD-L1/TGF-β Trap fusion protein (M7824) efficiently reverts mesenchymalization of human lung cancer cellsDavid, Justin M., Dominguez, Charli, McCampbell, Kristen K., Gulley, James L., Schlom, Jeffrey, Palena, Claudia · 2017 · OncoImmunology
- Immunotherapies: Exploiting the Immune System for Cancer TreatmentJeffrey Koury, Mariana Lucero, Caleb Cato, Lawrence Chang, Joseph Geiger, Denise Henry, Jennifer Hernandez, Fion Hung, Preet Kaur, Garrett Teskey et al. · 2018 · Journal of Immunology Research
- Dermatologic toxicities to immune checkpoint inhibitor therapy: A review of histopathologic featuresSamantha R. Ellis, Aren T Vierra, Jillian Wong Millsop, Mario E. Lacouture, Maija H. Kiuru · 2020 · Journal of the American Academy of Dermatology
- Inducible Expression of B7-H1 (PD-L1) and Its Selective Role in Tumor Site Immune ModulationMiguel F. Sanmamed, Lieping Chen · 2014 · The Cancer Journal
- Immunology beats cancer: a blueprint for successful translationDrew M. Pardoll · 2012 · Nature Immunology
- Combined PD-1 blockade and GITR triggering induce a potent antitumor immunity in murine cancer models and synergizes with chemotherapeutic drugsLei Lü, Xiaobing Xu, Bin Zhang, Rongsheng Zhang, Hongzan Ji, Xuan Wang · 2014 · Journal of Translational Medicine
- Clinicopathologic Analysis of PD-L1 and PD-L2 Expression in Renal Cell Carcinoma: Association with Oncogenic Proteins StatusSu‐Jin Shin, Yoon Kyung Jeon, Pil-Jong Kim, Yong Mee Cho, Jaemoon Koh, Doo Hyun Chung, Heounjeong Go · 2015 · Annals of Surgical Oncology
- PD-L1 expression in perihilar and intrahepatic cholangiocarcinomaJacqueline Fontugne, Jérémy Augustin, Anaïs Pujals, Philippe Compagnon, Benoı̂t Rousseau, Alain Luciani, Christophe Tournigand, Daniel Cherqui, Daniel Azoulay, Jean–Michel Pawlotsky et al. · 2017 · Oncotarget
- Targeting Tumors with IL-10 Prevents Dendritic Cell-Mediated CD8+ T Cell ApoptosisJian Qiao, Zhida Liu, Chunbo Dong, Yan Luan, Anli Zhang, Casey Moore, Kai Fu, Jianjian Peng, Yang Wang, Zhenhua Ren et al. · 2019 · Cancer Cell
- Deubiquitinating enzyme OTUB1 promotes cancer cell immunosuppression via preventing ER-associated degradation of immune checkpoint protein PD-L1Dan Zhu, Ruidan Xu, Xinping Huang, Zefang Tang, Yonglu Tian, Jinfang Zhang, Xiaofeng Zheng · 2020 · Cell Death and Differentiation
- Upregulation of PD-L1 and APE1 is associated with tumorigenesis and poor prognosis of gastric cancerYi Qing, Qing Li, Tao Ren, Wei Xia, Yu Peng, Gao lei Liu, Hao Luo, Yuxing Yang, Xiao Yan Dai, Shufeng Zhou et al. · 2015 · Drug Design Development and Therapy
- Significance of Programmed Cell Death-Ligand 1 Expression and its Association with Survival in Patients with Small Cell Lung CancerHidenobu Ishii, Koichi Azuma, Akihiko Kawahara, Kazuhiko Yamada, Yohei Imamura, Takaaki Tokito, Takashi Kinoshita, Masayoshi Kage, Tomoaki Hoshino · 2014 · Journal of Thoracic Oncology
- Serum levels of soluble programmed death ligand 1 predict treatment response and progression free survival in multiple myelomaLiang Wang, Hua Wang, Hao Chen, Wei-da Wang, Xiao-qin Chen, Qi-rong Geng, Zhong-Jun Xia, Yue Lu · 2015 · Oncotarget
- In a model of tumor dormancy, long-term persistent leukemic cells have increased B7-H1 and B7.1 expression and resist CTL-mediated lysisAurore Saudemont, Bruno Quesnel · 2004 · Blood
- PD-1 Expression on Peripheral Blood Cells Increases with Stage in Renal Cell Carcinoma Patients and Is Rapidly Reduced after Surgical Tumor ResectionAlexander W. Macfarlane, Mowafaq Jillab, Elizabeth R. Plimack, Gary R. Hudes, Robert G. Uzzo, Samuel Litwin, Essel Dulaimi, Tahseen Al‐Saleem, Kerry S. Campbell · 2013 · Cancer Immunology Research
- Emerging targeted agents in metastatic breast cancerDimitrios Zardavas, Jose M Baselga, Martine J Piccart · 2013 · Nature Reviews Clinical Oncology
- Assessment of Tumoral PD-L1 Expression and Intratumoral CD8+ T Cells in Urothelial CarcinomaSheila F. Faraj, Enrico Munari, Güneş Güner, Janis Marie Taube, Robert A. Anders, Jessica L Hicks, Alan Keith Meeker, Mark Schoenberg, Trinity Jude Bivalacqua, Charles G. Drake et al. · 2015 · Urology
- PD-L1 Binds to B7-1 Only In Cis on the Same Cell SurfaceApoorvi Chaudhri, Yanping Xiao, Alyssa N. Klee, Xiaoxu Wang, Baogong Zhu, Gordon James Freeman · 2018 · Cancer Immunology Research
- FcγR-Binding Is an Important Functional Attribute for Immune Checkpoint Antibodies in Cancer ImmunotherapyXin Chen, Xiaomin Song, Kang Li, Tong Zhang · 2019 · Frontiers in Immunology
- Sex Differences in Cancer Immunotherapy Efficacy, Biomarkers, and Therapeutic StrategyShixiang Wang, Li An Cowley, Xuesong Liu · 2019 · Molecules