Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
Dong, Haidong, Strome, Scott E., Salomao, Diva R., Tamura, Hideto, Hirano, Fumiya, Flies, Dallas B., Roche, Patrick C., Lu, Jun +5 more·2002·Nature Medicine
DOI 10.1038/nm730
Cited by (1,026)
Items 101–200 of 1,026
- Control of PD-L1 Expression by Oncogenic Activation of the AKT-mTOR Pathway in Non-Small Cell Lung Cancer.Lastwika, Kristin J., Wilson, Willie, Li, Qing Kay, Norris, Jeffrey, Xu, Haiying, Ghazarian, Sharon R., Kitagawa, Hiroshi, Kawabata, Shigeru, Taube, Janis M., Yao, Sheng et al. · 2016 · Cancer Research
- Evidence for a Role of the PD-1:PD-L1 Pathway in Immune Resistance of HPV-Associated Head and Neck Squamous Cell CarcinomaSofía Lyford-Pike, Shiwen Peng, Geoffrey D. Young, Janis Marie Taube, William H. Westra, Belinda Akpeng, Tullia Carmela Bruno, Jeremy D. Richmon, Hao Wang, Justin A. Bishop et al. · 2013 · Cancer Research
- Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic targetThompson, R. Houston, Gillett, Michael D., Cheville, John C., Lohse, Christine M., Dong, Haidong, Webster, W. Scott, Krejci, Kent G., Lobo, John R., Sengupta, Shomik, Chen, Lieping et al. · 2004 · Proceedings of the National Academy of Sciences
- PD-L1/B7H-1 Inhibits the Effector Phase of Tumor Rejection by T Cell Receptor (TCR) Transgenic CD8+ T CellsBlank, Christian, Brown, Ian, Peterson, Amy C., Spiotto, Mike, Iwai, Yoshiko, Honjo, Tasuku, Gajewski, Thomas F. · 2004 · Cancer Research
- CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell ActivationDeng, Jiehui, Wang, Eric S., Jenkins, Russell W., Li, Shuai, Dries, Ruben, Yates, Kathleen, Chhabra, Sandeep, Huang, Wei, Liu, Hongye, Aref, Amir R. et al. · 2018 · Cancer Discovery
- Modulation of the antitumor immune response by complementMaciej M. Markiewski, Robert A. DeAngelis, Fabián Benencia, Salome K. Ricklin-Lichtsteiner, Anna Koutoulaki, Craig J Gerard, George Coukos, John D. Lambris · 2008 · Nature Immunology
- Targeting FTO suppresses cancer stem cell maintenance and immune evasionR. Su, Lei Dong, Yang-Chan Li, Min Gao, Li Han, M. Wunderlich, Xiaolan Deng, Hongzhi Li, Yue Huang, Lei Gao et al. · 2020 · Cancer Cell
- Tumor biomarkers for diagnosis, prognosis and targeted therapyYue Zhou, Lei Tao, Jiahao Qiu, Jing Xu, Xinyu Yang, Yu Zhang, Xinyu Tian, Xinqi Guan, Xiaobo Cen, Yinglan Zhao · 2024 · Signal Transduction and Targeted Therapy
- Disruption of CXCR2-Mediated MDSC Tumor Trafficking Enhances Anti-PD1 EfficacyHighfill, Steven L., Cui, Yongzhi, Giles, Amber J., Smith, Jillian P., Zhang, Hua, Morse, Elizabeth, Kaplan, Rosandra N., Mackall, Crystal L. · 2014 · Science Translational Medicine
- A mechanism of hypoxia-mediated escape from adaptive immunity in cancer cellsBarsoum, Ivraym B., Smallwood, Chelsea A., Siemens, D. Robert, Graham, Charles H. · 2014 · Cancer Research
- The head and neck cancer immune landscape and its immunotherapeutic implicationsRajarsi Mandal, Yasin Şenbabaoğlu, Alexis Desrichard, Jonathan J. Havel, Martin G. Dalin, Nadeem Riaz, Ken-Wing Lee, Ian Ganly, A. Ari Hakimi, Timothy An-thy Chan et al. · 2016 · JCI Insight
- Programmed death ligand-1 expression in non-small cell lung cancerVamsidhar Velcheti, Kurt Alex Schalper, Daniel E Carvajal, Valsamo Anagnostou, Konstantinos Nikolaos Syrigos, Mario Sznol, Roy S. Herbst, Scott N. Gettinger, Lieping Chen, David L. Rimm · 2013 · Laboratory Investigation
- B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinomaKryczek, Ilona, Zou, Linhua, Rodriguez, Paulo, Zhu, Gefeng, Wei, Shuang, Mottram, Peter, Brumlik, Michael, Cheng, Pui, Curiel, Tyler, Myers, Leann et al. · 2006 · The Journal of Experimental Medicine
- Avelumab, an anti-PD-L1 antibody, in patients with locally advanced or metastatic breast cancer: a phase 1b JAVELIN Solid Tumor studyLuc Yves Dirix, István Takács, Guy Jérusalem, Petros G. Nikolinakos, Hendrik‐Tobias Arkenau, Andres Forero, Ralph Vincent Boccia, Marc E. Lippman, Robert A. Somer, Martin Šmakal et al. · 2017 · Breast Cancer Research and Treatment
- Immune checkpoint inhibitors of PD-L1 as cancer therapeuticsAkintunde Akinleye, Zoaib Rasool · 2019 · Journal of Hematology & Oncology
- Dual Blockade of PD-1 and CTLA-4 Combined with Tumor Vaccine Effectively Restores T-Cell Rejection Function in TumorsJaikumar Duraiswamy, Karen M. Kaluza, Gordon James Freeman, George Coukos · 2013 · Cancer Research
- Evaluation of Immune-Related Response Criteria and RECIST v1.1 in Patients With Advanced Melanoma Treated With PembrolizumabFrank Stephen Hodi, Wen‐Jen Hwu, Richard F. Kefford, Jeffrey S. Weber, ADIL I. DAUD, Omid Hamid, Amita Patnaik, Antoni Ribas, Caroline Robert, Tara C. Gangadhar et al. · 2016 · Journal of Clinical Oncology
- Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and CancerWing, James B., Tanaka, Atsushi, Sakaguchi, Shimon · 2019 · Immunity
- The PD-1–PD-L pathway in immunological toleranceTaku Okazaki, Tasuku Honjo · 2006 · Trends in Immunology
- VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responsesLi Lily Wang, Rotem Rubinstein, Janet Louise Lines, Anna Wasiuk, Cory L. Ahonen, Yanxia Guo, Li‐Fan Lu, David C. Gondek, Yan Wang, Roy A. Fava et al. · 2011 · The Journal of Experimental Medicine
- B7-H4, a Molecule of the B7 Family, Negatively Regulates T Cell ImmunityGabriel Sica, In-Hak Choi, Gefeng Zhu, Koji Tamada, Sheng-Dian Wang, Hideto Tamura, Andrei I. Chapoval, Dallas B. Flies, Jürgen Bajorath, Lieping Chen · 2003 · Immunity
- Vaccines for established cancer: overcoming the challenges posed by immune evasionSjoerd H. van der Burg, Ramon Arens, FERRY A. OSSENDORP, Thorbald van Hall, Cornelis J.M. Melief · 2016 · Nature reviews. Cancer
- Neoantigen vaccine: an emerging tumor immunotherapyPeng Miao, Yongzhen Mo, Yian Wang, Pan Wu, Yijie Zhang, Fang Xiong, Can Jie Guo, Steven Wu, Yong Li, Xiaoling Li et al. · 2019 · Molecular Cancer
- Mechanisms of Immune Evasion by TumorsCharles G. Drake, Elizabeth M. Jaffee, Drew M. Pardoll · 2006 · Advances in immunology
- CTLA-4 and PD-1/PD-L1 Blockade: New Immunotherapeutic Modalities with Durable Clinical Benefit in Melanoma PatientsPatrick Alexander Ott, Frank Stephen Hodi, Caroline Robert · 2013 · Clinical Cancer Research
- Cancer immunotherapy—immune checkpoint blockade and associated endocrinopathies.Byun, David J., Wolchok, Jedd D., Rosenberg, Lynne M., Girotra, Monica · 2017 · Nature Reviews Endocrinology
- Phase I Safety and Pharmacokinetic Study of CT-011, a Humanized Antibody Interacting with PD-1, in Patients with Advanced Hematologic MalignanciesRaanan Berger, Rinat Rotem‐Yehudar, Gideon Slama, Shimon Landes, Abraham Kneller, Merav Leiba, Maya Koren‐Michowitz, Avichai Shimoni, Arnon Nagler · 2008 · Clinical Cancer Research
- B7-H1 Expression on Non-Small Cell Lung Cancer Cells and Its Relationship with Tumor-Infiltrating Lymphocytes and Their PD-1 ExpressionJun Sakakibara Konishi, Koichi Yamazaki, Miyuki Azuma, Ichiro Kinoshita, Hirotoshi Dosaka‐Akita, Masaharu Nishimura · 2004 · Clinical Cancer Research
- Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapyJun Wang, Jingwei Sun, Linda N. Liu, Dallas B. Flies, Xinxin Nie, Maria I Toki, Jianping Zhang, Chang Cheng Song, Melissa A. Zarr, Xu Zhou et al. · 2019 · Nature Medicine
- Tumor cell expression of programmed cell death‐1 ligand 1 is a prognostic factor for malignant melanomaRyosuke Hino, Kenji Kabashima, Yu Kato, Hiroaki Yagi, Motonobu Nakamura, Tasuku Honjo, Taku Okazaki, YOSHIKI TOKURA · 2010 · Cancer
- Improving immunotherapy outcomes with anti-angiogenic treatments and vice versaKabir A. Khan, Robert S. Kerbel · 2018 · Nature Reviews Clinical Oncology
- CD8 T Cell Exhaustion in Chronic Infection and Cancer: Opportunities for InterventionsMasao Hashimoto, Alice Oliffson Kamphorst, Se Jin Im, Haydn Thomas Kissick, Rathi Narayana Pillai, Suresh S. Ramalingam, Koichi Araki, Rafi Ahmed · 2018 · Annual Review of Medicine
- HUMAN T CELL RESPONSES AGAINST MELANOMAThierry Boon, Pierre G. Coulie, Benoit J. Van den Eynde, Pierre van der Bruggen · 2005 · Annual Review of Immunology
- Immune escape to PD-L1/PD-1 blockade: seven steps to success (or failure)Kim, J.M., Chen, D.S. · 2016 · Annals of Oncology
- Molecular Pathways: Next-Generation Immunotherapy—Inhibiting Programmed Death-Ligand 1 and Programmed Death-1Daniel S. Chen, Bryan A. Irving, Frank Stephen Hodi · 2012 · Clinical Cancer Research
- Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor GrowthSonja Kleffel, Christian Posch, Steven R. Barthel, Hansgeorg Mueller, Christoph Schlapbach, Emmanuella Guenova, Christopher P. Elco, Nayoung Lee, Vikram R. Juneja, Qian Zhan et al. · 2015 · Cell
- Mechanisms of Resistance to Immune Checkpoint Blockade: Why Does Checkpoint Inhibitor Immunotherapy Not Work for All Patients?Charlene Marie Fares, Eliezer M. Van Allen, Charles G. Drake, James Patrick Allison, Siwen Hu‐Lieskovan · 2019 · American Society of Clinical Oncology Educational Book
- Regulation of PD‐1, PD‐L1, and PD‐L2 expression during normal and autoimmune responsesSpencer C. Liang, Yvette E Latchman, Janet E. Buhlmann, Michal F. Tomczak, Bruce Harold Horwitz, Gordon James Freeman, Arlene H. Sharpe · 2003 · European Journal of Immunology
- Interaction of PD-L1 on tumor cells with PD-1 on tumor-specific T cells as a mechanism of immune evasion: implications for tumor immunotherapyChristian U. Blank, Thomas Frank Gajewski, Andréas Mackensen · 2004 · Cancer Immunology Immunotherapy
- PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cellsYvette E Latchman, Spencer C. Liang, Yin Wu, Tatyana Chernova, Raymond A. Sobel, Martina Klemm, Vijay Kumar Kuchroo, Gordon James Freeman, Arlene H. Sharpe · 2004 · Proceedings of the National Academy of Sciences
- PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cellsP’ng Loke, James Patrick Allison · 2003 · Proceedings of the National Academy of Sciences
- Immunostimulatory monoclonal antibodies for cancer therapyIgnacio Melero, Sandra Hervás‐Stubbs, Martin J. Glennie, Drew M. Pardoll, Lieping Chen · 2007 · Nature reviews. Cancer
- Clinical Significance of PD-L1+ Exosomes in Plasma of Head and Neck Cancer PatientsTheodoraki, Marie-Nicole, Yerneni, Saigopalakrishna S., Hoffmann, Thomas K., Gooding, William E., Whiteside, Theresa L. · 2018 · Clinical Cancer Research
- CD8+CD103+ Tumor–Infiltrating Lymphocytes Are Tumor-Specific Tissue-Resident Memory T Cells and a Prognostic Factor for Survival in Lung Cancer PatientsDjenidi, Fayçal, Adam, Julien, Goubar, Aïcha, Durgeau, Aurélie, Meurice, Guillaume, de Montpréville, Vincent, Validire, Pierre, Besse, Benjamin, Mami-Chouaib, Fathia · 2015 · The Journal of Immunology
- Clinical blockade of PD1 and LAG3 — potential mechanisms of actionLinh T. Nguyen, Pamela S. Ohashi · 2014 · Nature reviews. Immunology
- Interferon γ and Its Important Roles in Promoting and Inhibiting Spontaneous and Therapeutic Cancer ImmunityElise Alspach, Danielle M. Lussier, Robert D. Schreiber · 2018 · Cold Spring Harbor Perspectives in Biology
- Prostate cancer and inflammation: the evidenceKaren Sandell Sfanos, Angelo Michael De Marzo · 2011 · Histopathology
- The B7-H1 (PD-L1) T Lymphocyte-Inhibitory Molecule Is Expressed in Breast Cancer Patients with Infiltrating Ductal Carcinoma: Correlation with Important High-Risk Prognostic FactorsHazem Ghebeh, Shamayel F. Mohammed, Abeer Al-Omair, Amal T. Qattan, Cynthia L. Lehé, Ghofran Al-Qudaihi, Naser B. Elkum, Mohamed Alshabanah, Suad M. Bin Amer, Asma M. Tulbah et al. · 2006 · Neoplasia
- Emerging Concepts in the Immunopathogenesis of AIDSDaniel C. Douek, Mario Roederer, Richard A. Koup · 2008 · Annual Review of Medicine
- Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1Chia‐Wei Li, Seung‐Oe Lim, Ezra M. Chung, Yongsoo Kim, Andrew H Park, Jun Yao, Jong‐Ho Cha, Weiya Xia, Li-Chuan Chan, Tae‐Wan Kim et al. · 2018 · Cancer Cell
- The PD1:PD-L1/2 Pathway from Discovery to Clinical ImplementationBardhan, Kankana, Anagnostou, Theodora, Boussiotis, Vassiliki A. · 2016 · Frontiers in Immunology
- In Vitro Characterization of the Anti-PD-1 Antibody Nivolumab, BMS-936558, and In Vivo Toxicology in Non-Human PrimatesChangyu Wang, Kent B. Thudium, Minhua Han, Xitao Wang, Haichun Huang, Diane Feingersh, Candy Garcia, Yi Ming Wu, Michelle R. Kuhné, Mohan Srinivasan et al. · 2014 · Cancer Immunology Research
- Deciphering and Reversing Tumor Immune SuppressionGregory T. Motz, George Coukos · 2013 · Immunity
- Cancer stem cells: advances in knowledge and implications for cancer therapyXianjing Chu, Wentao Tian, Jiaoyang Ning, Gang Xiao, Yunqi Zhou, Ziqi Wang, Zhuofan Zhai, Guilong Tanzhu, Jie Yang, Rongrong Zhou · 2024 · Signal Transduction and Targeted Therapy
- Cancer Immunotherapy Comes of AgeSuzanne Louise Topalian, George J. Weiner, Drew M. Pardoll · 2011 · Journal of Clinical Oncology
- Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-γ and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathwayJizhong Liu, Abdelbasset Hamrouni, Dariusz Wołowiec, Valérie Coiteux, Kazimierz Kuliczkowski, Dominique Hétuin, Aurore Saudemont, Bruno Quesnel · 2007 · Blood
- Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade–mediated tumor regressionHeng Lin, Shuang Wei, Elaine M. Hurt, Michael D. Green, Lili Zhao, Linda Vatan, Wojciech Szeliga, Ronald Herbst, Paul W. Harms, Leslie Anne Fecher et al. · 2018 · Journal of Clinical Investigation
- Checkpoint Blockade in Cancer ImmunotherapyAlan J. Korman, Karl S. Peggs, James Patrick Allison · 2006 · Advances in immunology
- High expression of PD-L1 in lung cancer may contribute to poor prognosis and tumor cells immune escape through suppressing tumor infiltrating dendritic cells maturationChuanyong Mu, Jian‐An Huang, Ying Chen, Cheng Chen, Xueguang Zhang · 2010 · Medical Oncology
- The B7 family member B7-H3 preferentially down-regulates T helper type 1–mediated immune responsesSuh, Woong-Kyung, Gajewska, Beata U, Okada, Hitoshi, Gronski, Matthew A, Bertram, Edward M, Dawicki, Wojciech, Duncan, Gordon S, Bukczynski, Jacob, Plyte, Suzanne, Elia, Andrew et al. · 2003 · Nature Immunology
- Autophagy, Inflammation, and Immunity: A Troika Governing Cancer and Its TreatmentZhenyu Zhong, Elsa Sánchez‐López, Michael Karin · 2016 · Cell
- Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF V600E melanomaSiwen Hu‐Lieskovan, Stephen Mok, Blanca Homet Moreno, Jennifer Tsoi, Lídia Robert, Lucas Goedert, Elaine M. Pinheiro, Richard Chikara Koya, Thomas G. Graeber, Begoña Comı́n-Anduix et al. · 2015 · Science Translational Medicine
- Improving immune–vascular crosstalk for cancer immunotherapyHuang, Yuhui, Kim, Betty Y. S., Chan, Charles K., Hahn, Stephen M., Weissman, Irving L., Jiang, Wen · 2018 · Nature Reviews Immunology
- PD-1/PD-L1 inhibitorsJoel Chaim Sunshine, Janis Marie Taube · 2015 · Current Opinion in Pharmacology
- The foundations of immune checkpoint blockade and the ipilimumab approval decennialAlan J. Korman, Sarah C. Garrett-Thomson, Nils Lönberg · 2021 · Nature Reviews Drug Discovery
- DNA mismatch repair in cancerMarina Baretti, Dung Thi Le · 2018 · Pharmacology & Therapeutics
- Expression of programmed death ligand 1 (PD-L1) is associated with poor prognosis in human breast cancerSimone E. Muenst, A. R. Schaerli, Feng Gao, Silvio Däster, Emanuele Trella, Raoul Andre Droeser, Manuele Giuseppe Muraro, Paul Zajac, Rosanna Zanetti, William E. Gillanders et al. · 2014 · Breast Cancer Research and Treatment
- Immune-mediated antitumor effect by type 2 diabetes drug, metforminShingo Eikawa, Mikako Nishida, Shusaku Mizukami, Chihiro Yamazaki, Eiichi Nakayama, Heiichiro Udono · 2015 · Proceedings of the National Academy of Sciences
- Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8(+) T cells directly within the tumor microenvironmentSpranger, Stefani, Koblish, Holly K, Horton, Brendan, Scherle, Peggy A, Newton, Robert, Gajewski, Thomas F · 2014 · Journal for ImmunoTherapy of Cancer
- Signaling pathways involved in colorectal cancer: pathogenesis and targeted therapyLi, Qing, Geng, Shan, Luo, Hao, Wang, Wei, Mo, Ya-Qi, Luo, Qing, Wang, Lu, Song, Guan-Bin, Sheng, Jian-Peng, Xu, Bo · 2024 · Signal Transduction and Targeted Therapy
- Erratum: Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasionHaidong Dong, Scott Eric Strome, Diva R. Salomão, Hideto Tamura, Fumiya Hirano, Dallas B. Flies, Patrick C. Roche, Jun Lu, Gefeng Zhu, Koji Tamada et al. · 2002 · Nature Medicine
- Toll-Like Receptors on Tumor Cells Facilitate Evasion of Immune SurveillanceBo Huang, Jie Zhao, Hongxing Li, Kai‐Li He, Yibang Chen, Lloyd F. Mayer, Jay C. Unkeless, Huabao Xiong · 2005 · Cancer Research
- Tumor Immunology and Tumor Evolution: Intertwined HistoriesJérôme Galon, Daniela Bruni · 2020 · Immunity
- Revisiting the PD-1 pathwayNikolaos Patsoukis, Qi Wang, Laura Strauss, Vassiliki A. Boussiotis · 2020 · Science Advances
- Coinhibitory Pathways in the B7-CD28 Ligand-Receptor FamilyFrank Alexander Schildberg, Sarah R. Klein, Gordon James Freeman, Arlene H. Sharpe · 2016 · Immunity
- Safety and Efficacy of Pembrolizumab in Advanced, Programmed Death Ligand 1–Positive Cervical Cancer: Results From the Phase Ib KEYNOTE-028 TrialJean‐Sébastien Frenel, Christophe Le Tourneau, Bert H. O’Neil, Patrick Alexander Ott, Sarina Anne Piha-Paul, Carlos Gomez‐Roca, Emilie M.J. van Brummelen, Hope S. Rugo, Shari Thomas, Sanatan Saraf et al. · 2017 · Journal of Clinical Oncology
- Tumour immunity: effector response to tumour and role of the microenvironmentAlberto Mantovani, Pedro J. Romero, Anna Karolina Palucka, Francesco Maria Marincola · 2008 · The Lancet
- Safety, efficacy, and biomarkers of nivolumab with vaccine in ipilimumab-refractory or -naive melanomaWeber, Jeffrey S., Kudchadkar, Ragini Reiney, Yu, Bin, Gallenstein, Donna, Horak, Christine E., Inzunza, H. David, Zhao, Xiuhua, Martinez, Alberto J., Wang, Wenshi, Gibney, Geoffrey et al. · 2013 · Journal of Clinical Oncology
- Updates on global epidemiology, risk and prognostic factors of gastric cancerWenjuan Yang, Heping Zhao, Yan Ping Yu, Ji-Han Wang, Lei Guo, Jun-Ye Liu, Jie Pu, Jing Lv · 2023 · World Journal of Gastroenterology
- Targeting tumours with genetically enhanced T lymphocytesMichel Sadelain, Isabelle Rivière, Renier J. Brentjens · 2003 · Nature reviews. Cancer
- Roles of PD-1/PD-L1 Pathway: Signaling, Cancer, and BeyondLuoyan Ai, Antao Xu, Jie Xu · 2020 · Advances in experimental medicine and biology
- Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejectionNatalia Rubinstein, Mariano J. Alvarez, Norberto W. Zwirner, Marta A. Toscano, Juan M. Ilarregui, Alicia Bravo, José Mordoh, Leonardo Fainboim, Osvaldo Luis Podhajcer, Gabriel A. Rabinovich · 2004 · Cancer Cell
- Antagonist Antibodies to PD-1 and B7-H1 (PD-L1) in the Treatment of Advanced Human Cancer—ResponseMario Sznol, Lieping Chen · 2013 · Clinical Cancer Research
- B7-H1 is a ubiquitous antiapoptotic receptor on cancer cellsTakeshi Azuma, Sheng Yao, Gefeng Zhu, Andrew S. Flies, Sarah J. Flies, Lieping Chen · 2008 · Blood
- PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cellsIwai, Y. · 2004 · International Immunology
- Application of PD-1 Blockade in Cancer ImmunotherapyXiaomo Wu, Zhongkai Gu, Chen Yang, Borui Chen, Wei Chen, Liqiang Weng, Xiaolong Liu · 2019 · Computational and Structural Biotechnology Journal
- Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-responseDongrui Wang, Xianlin Wu, Yingli Sun · 2022 · Signal Transduction and Targeted Therapy
- Immune Modulation in Cancer with AntibodiesDavid B. Page, Michael A. Postow, Margaret K. Callahan, James Patrick Allison, Jedd D. Wolchok · 2013 · Annual Review of Medicine
- The Common γ-Chain Cytokines IL-2, IL-7, IL-15, and IL-21 Induce the Expression of Programmed Death-1 and Its LigandsKinter, Audrey L., Godbout, Emily J., McNally, Jonathan P., Sereti, Irini, Roby, Gregg A., O’Shea, Marie A., Fauci, Anthony S. · 2008 · The Journal of Immunology
- Role of the Tumor Microenvironment in Breast CancerSavas Deniz Soysal, Alexandar Tzankov, Simone E. Muenst · 2015 · Pathobiology
- Pembrolizumab (Keytruda)Gin Wai Kwok, Thomas C. C. Yau, Joanne Wing Yan Chiu, Eric Tse, Yok‐Lam Kwong · 2016 · Human Vaccines & Immunotherapeutics
- 5‐Fluorouracil resistance mechanisms in colorectal cancer: From classical pathways to promising processesBlondy, Sabrina, David, Valentin, Verdier, Mireille, Mathonnet, Muriel, Perraud, Aurélie, Christou, Niki · 2020 · Cancer Science
- Prognostic and predictive value of PDL1 expression in breast cancerRenaud Sabatier, Pascal Finetti, Émilie Mamessier, José Adélaı̈de, Max Chaffanet, Hamid Raza Ali, Patrice Viens, Carlos Caldas, Daniel Birnbaum, François Bertucci · 2014 · Oncotarget
- Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: an update on implications for chronic infections and tumor evasionChristian U. Blank, Andréas Mackensen · 2006 · Cancer Immunology Immunotherapy
- Critical Role of the Programmed Death-1 (PD-1) Pathway in Regulation of Experimental Autoimmune EncephalomyelitisAlan David Salama, Tanuja Chitnis, Jaime Imitola, Mohammed Javeed Ansari, Hisaya Akiba, Fumihiko Tushima, Miyuki Azuma, Hideo Yagita∥, Mohamed H. Sayegh, Samia Joseph Khoury · 2003 · The Journal of Experimental Medicine
- Tim-3/galectin-9 signaling pathway mediates T-cell dysfunction and predicts poor prognosis in patients with hepatitis B virus-associated hepatocellular carcinomaLi, Hang, Wu, Ke, Tao, Kaixiong, Chen, Libo, Zheng, Qichang, Lu, Xiaoming, Liu, Jun, Shi, Liang, Liu, Chuanqiao, Wang, Guobin et al. · 2012 · Hepatology
- COX2/mPGES1/PGE
<sub>2</sub>
pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cellsPrima, Victor, Kaliberova, Lyudmila N., Kaliberov, Sergey, Curiel, David T., Kusmartsev, Sergei · 2017 · Proceedings of the National Academy of Sciences
- Immunohistochemical localization of programmed death-1 ligand-1 (PD-L1) in gastric carcinoma and its clinical significanceChangping Wu, Yibei Zhu, Jingting Jiang, Jiemin Zhao, Xueguang Zhang, Ning Xu · 2006 · Acta Histochemica
- Antagonist Antibodies to PD-1 and B7-H1 (PD-L1) in the Treatment of Advanced Human CancerMario Sznol, Lieping Chen · 2013 · Clinical Cancer Research
- B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma.Scott Eric Strome, Haidong Dong, Hideto Tamura, Stephen G. Voss, Dallas B. Flies, Koji Tamada, Diva R. Salomão, John C. Cheville, Fumiya Hirano, Wei Yu Lin et al. · 2003 · PubMed