The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Porous metal–organic-framework nanoscale carriers as a potential platform for drug delivery and imaging
Open accessAbstract
In the domain of health, one important challenge is the efficient delivery of drugs in the body using non-toxic nanocarriers. Most of the existing carrier materials show poor drug loading (usually less than 5 wt% of the transported drug versus the carrier material) and/or rapid release of the proportion of the drug that is simply adsorbed (or anchored) at the external surface of the nanocarrier. In this context, porous hybrid solids, with the ability to tune their structures and porosities for better drug interactions and high loadings, are well suited to serve as nanocarriers for delivery and imaging applications. Here we show that specific non-toxic porous iron(III)-based metal-organic frameworks with engineered cores and surfaces, as well as imaging properties, function as superior nanocarriers for efficient controlled delivery of challenging antitumoural and retroviral drugs (that is, busulfan, azidothymidine triphosphate, doxorubicin or cidofovir) against cancer and AIDS. In addition to their high loadings, they also potentially associate therapeutics and diagnostics, thus opening the way for theranostics, or personalized patient treatments.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Nanocarriers as an emerging platform for cancer therapy
Peer, D., Karp, J. M., Hong, S., Farokhzad, O. C., Margalit, R., & Langer, R. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.387 · Cited by 8,710
Cited by
BioMOFs: Metal–Organic Frameworks for Biological and Medical Applications
McKinlay, A. C., Morris, R. E., Horcajada, P., Férey, G., Gref, R., Couvreur, P., & Serre, C. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.201000048 · Cited by 1,256
Self-citationLuminescent sensors based on metal-organic frameworks
Zhang, Y., Yuan, S., Day, G., Wang, X., Yang, X., & Zhou, H.-C. (2018) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2017.06.007 · Cited by 1,255
Metal–organic frameworks as platforms for clean energy
Li, S.-L., & Xu, Q. (2013) · Energy & Environmental Science · doi:10.1039/c3ee40507a · Cited by 970
Cravillon, J., Nayuk, R., Springer, S., Feldhoff, A., Huber, K., & Wiebcke, M. (2011) · Chemistry of Materials · doi:10.1021/cm103571y · Cited by 916
Metal–Organic Frameworks for Drug Delivery: A Design Perspective
Lawson, H. D., Walton, S. P., & Chan, C. (2021) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.1c01089 · Cited by 916
Metadata
- Authors
- Horcajada, P., Chalati, T., Serre, C., Gillet, B., Sebrie, C., Baati, T., Eubank, J. F., Heurtaux, D., Clayette, P., Kreuz, C., Chang, J.-S., Hwang, Y. K., Marsaud, V., Bories, P.-N., Cynober, L., Gil, S., Férey, G., Couvreur, P., & Gref, R.
- Venue
- Nature Materials
- Published
- 2009-12-13
- Volume
- 9
- Issue
- 2
- Pages
- 172-178
- ISSN
- 1476-1122 (ISSN-L)
- 1476-4660
- OpenAlex
- W2066991705
- Cited by
- 4,260
- References
- 1
- FWCI
- 70.12
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Porous metal–organic-framework nanoscale carriers as a potential platform for drug delivery and imaging. https://app.cochat.ai/papers/10.1038/nmat2608
- The paper
- Horcajada, P., Chalati, T., Serre, C., Gillet, B., Sebrie, C., Baati, T., Eubank, J. F., Heurtaux, D., Clayette, P., Kreuz, C., Chang, J.-S., Hwang, Y. K., Marsaud, V., Bories, P.-N., Cynober, L., Gil, S., Férey, G., Couvreur, P., & Gref, R. (2010). Porous metal–organic-framework nanoscale carriers as a potential platform for drug delivery and imaging. Nature Materials. https://doi.org/10.1038/nmat2608
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
