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Cited by 758

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Fluorescence nanoscopy by ground-state depletion and single-molecule return

Open access
Fölling, Jonas, Bossi, Mariano, Bock, Hannes, Medda, Rebecca, Wurm, Christian A, Hein, Birka, Jakobs, Stefan, Eggeling, Christian, Hell, Stefan W·2008·Nature Methods

Abstract

We introduce far-field fluorescence nanoscopy with ordinary fluorophores based on switching the majority of them to a metastable dark state, such as the triplet, and calculating the position of those left or those that spontaneously returned to the ground state. Continuous widefield illumination by a single laser and a continuously operating camera yielded dual-color images of rhodamine- and fluorescent protein–labeled (living) samples, proving a simple yet powerful super-resolution approach.

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Crossref · 10.1038/nmeth.1257

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Metadata

Authors
Fölling, J., Bossi, M., Bock, H., Medda, R., Wurm, C. A., Hein, B., Jakobs, S., Eggeling, C., & Hell, S. W.
Venue
Nature Methods
Published
2008-09-15
Volume
5
Issue
11
Pages
943-945
ISSN
  • 1548-7091 (ISSN-L)
  • 1548-7105
OpenAlex
W2103241853
Cited by
758
References
1
FWCI
22.15
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Fluorescence nanoscopy by ground-state depletion and single-molecule return. https://app.cochat.ai/papers/10.1038/nmeth.1257
The paper
Fölling, J., Bossi, M., Bock, H., Medda, R., Wurm, C. A., Hein, B., Jakobs, S., Eggeling, C., & Hell, S. W. (2008). Fluorescence nanoscopy by ground-state depletion and single-molecule return. Nature Methods. https://doi.org/10.1038/nmeth.1257

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