Quantitative analysis of fitness and genetic interactions in yeast on a genome scale

Baryshnikova, Anastasia, Costanzo, Michael, Kim, Yungil, Ding, Huiming, Koh, Judice, Toufighi, Kiana, Youn, Ji-Young, Ou, Jiongwen +11 more·2010·Nature Methods

Cited by (364)

Items 101–200 of 364

  1. Yeast as a Heterologous Model System to Uncover Type III Effector Function
    Crina Popa, Núria S. Coll, Marc Valls, Guido Sessa · 2016 · PLoS Pathogens
  2. Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs
    Mount, Harley O’Connor, Revie, Nicole M., Todd, Robert T., Anstett, Kaitlin, Collins, Cathy, Costanzo, Michael, Boone, Charles, Robbins, Nicole, Selmecki, Anna, Cowen, Leah E. · 2018 · PLOS Genetics
  3. Yeast genetic interaction screens in the age of CRISPR/Cas
    Neil R. Adames, Jenna E. Gallegos, Jean Peccoud · 2018 · Current Genetics
  4. Exploratory Analysis of Biological Networks through Visualization, Clustering, and Functional Annotation in Cytoscape
    Anastasia Baryshnikova · 2016 · Cold Spring Harbor Protocols
  5. Proteome-scale movements and compartment connectivity during the eukaryotic cell cycle
    Athanasios Litsios, Benjamin Grys, Oren Z. Kraus, Helena Friesen, Catherine Ross, Myra Paz David Masinas, Duncan T. Forster, Mary Couvillion, Stefanie Timmermann, Maximilian Billmann et al. · 2024 · Cell
  6. A scalable double-barcode sequencing platform for characterization of dynamic protein-protein interactions
    Ulrich Schlecht, Zhimin Liu, Jamie R. Blundell, Robert P. St.Onge, Sasha F. Levy · 2017 · Nature Communications
  7. Comparison of Profile Similarity Measures for Genetic Interaction Networks
    Raamesh Deshpande, Benjamin VanderSluis, Chad L. Myers · 2013 · PLoS ONE
  8. CRISPR-mediated genetic interaction profiling identifies RNA binding proteins controlling metazoan fitness
    Adam D. Norris, Xicotencatl Gracida, John A. Calarco · 2017 · eLife
  9. Chemical-genomic profiling: Systematic analysis of the cellular targets of bioactive molecules
    Kerry Andrusiak, Jeff S. Piotrowski, Charles M. Boone · 2011 · Bioorganic & Medicinal Chemistry
  10. EURASIP Journal on Bioinformatics and Systems Biology
    2013 · EURASIP Journal on Bioinformatics and Systems Biology
  11. AlphaDesign: a de novo protein design framework based on AlphaFold
    2025
  12. All or Nothing: Protein Complexes Flip Essentiality between Distantly Related Eukaryotes
    Colm J. Ryan, Nevan J. Krogan, Pádraig Cunningham, Gerard Cagney · 2013 · Genome Biology and Evolution
  13. Exploring Quantitative Yeast Phenomics with Single-Cell Analysis of DNA Damage Foci
    Erin B. Styles, Karen Founk, Lee Zamparo, Tina Lynn Sing, Dogus Murat Altintas, Cyril Ribeyre, Virginie Ribaud, Jacques Rougemont, David N. Mayhew, Michael Costanzo et al. · 2016 · Cell Systems
  14. Genome-wide Analysis Reveals Novel and Discrete Functions for Tubulin Carboxy-Terminal Tails
    Jayne Aiken, David Sept, Michael Costanzo, Charles M. Boone, John A. Cooper, Jeffrey K. Moore · 2014 · Current Biology
  15. Natural variants suppress mutations in hundreds of essential genes
    Leopold Parts, Amandine Batté, Maykel Lopes, Michael Wai-Keong Yuen, Meredith Laver, Bryan-Joseph San Luis, Jia‐Xing Yue, Carles Pons, Elise Eray, Patrick Aloy et al. · 2021 · Molecular Systems Biology
  16. Tiered Assembly of the Yeast Far3-7-8-9-10-11 Complex at the Endoplasmic Reticulum
    Tammy Pracheil, Zhengchang Liu · 2013 · Journal of Biological Chemistry
  17. Development of Ultra-High-Density Screening Tools for Microbial “Omics”
    Gordon J. Bean, Philipp A. Jaeger, Sondra Bahr, Trey Ideker · 2014 · PLoS ONE
  18. Synthetic lethal approaches for assessing combinatorial efficacy of chemotherapeutic drugs
    Rebecca A. Jackson, Ee Sin Chen · 2016 · Pharmacology & Therapeutics
  19. Synthetic Genetic Array Analysis
    Elena Kuzmin, Michael Costanzo, Brenda Andrews, Charles M. Boone · 2016 · Cold Spring Harbor Protocols
  20. Constructing module maps for integrated analysis of heterogeneous biological networks
    David Amar, Ron Shamir A · 2014 · Nucleic Acids Research
  21. Synthetic Lethality between Gene Defects Affecting a Single Non-essential Molecular Pathway with Reversible Steps
    Andrei Y. Zinovyev, Inna Kuperstein, Emmanuel Barillot, Wolf‐Dietrich Heyer · 2013 · PLoS Computational Biology
  22. Direct screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1
    Hanneke Vlaming, Thom M. Molenaar, Tibor van Welsem, Deepani W. Poramba‐Liyanage, Desirée E.C. Smith, Arno Velds, Liesbeth Hoekman, Tessy Korthout, Sjoerd Hendriks, Maarten A. F. Altelaar et al. · 2016 · eLife
  23. Use of genetic and chemical synthetic lethality as probes of complexity in bacterial cell systems
    Kristina Klobucar, Eric D. Brown · 2017 · FEMS Microbiology Reviews
  24. Evolutionary constraints in variable environments, from proteins to networks
    Katja M. Taute, Sebastian Gude, Philippe Nghe, Sander J. Tans · 2014 · Trends in Genetics
  25. Single cell functional genomics reveals the importance of mitochondria in cell-to-cell phenotypic variation
    Riddhiman Dhar, Alsu Missarova, Ben Lehner, Lucas B. Carey · 2019 · eLife
  26. Integrated analysis of numerous heterogeneous gene expression profiles for detecting robust disease-specific biomarkers and proposing drug targets
    David Amar, Tom Aharon Hait, Shai Izraeli, Ron Shamir A · 2015 · Nucleic Acids Research
  27. 38 Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome
    Andrew J. Finch, Christine Hilcenko, Nicolas Basse, Lesley F. Drynan, Beatriz Goyenechea, Tobias Menne, Á. González Fernández, Peter J. Simpson, Clive S. D’Santos, Mark Johan Arends et al. · 2011 · Leukemia Research
  28. Unligated Okazaki Fragments Induce PCNA Ubiquitination and a Requirement for Rad59-Dependent Replication Fork Progression
    Hai Dang Nguyen, Jordan R. Becker, Yee Mon Thu, Michael Costanzo, Elizabeth N. Koch, Stephanie N. Smith, Kyungjae Myung, Chad L. Myers, Charles M. Boone, Anja‐Katrin Bielinsky · 2013 · PLoS ONE
  29. Synthetic Lethal Networks for Precision Oncology: Promises and Pitfalls
    John Paul Shen, Trey Ideker · 2018 · Journal of Molecular Biology
  30. A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A
    Sultan Ciftci-Yilmaz, Wei-Chun Au, Prashant K Mishra, Jessica R. Eisenstatt, Joy W. Chang, Anthony R. Dawson, Iris Zhu, Mahfuzur Rahman, Sven Bilke, Michael Costanzo et al. · 2018 · Genetics
  31. Synthetic lethal gene pairs: Experimental approaches and predictive models
    Shan Tang, Birkan Gökbağ, Kunjie Fan, Shuai Shao, Yang Huo, Xue Wu, Lijun Cheng, Lang Li · 2022 · Frontiers in Genetics
  32. Roles of Mitochondrial Dynamics under Stressful and Normal Conditions in Yeast Cells
    Дмитрий Алексеевич Кнорре, Konstantin Yu. Popadin, С. С. Соколов, Fedor F. Severin · 2013 · Oxidative Medicine and Cellular Longevity
  33. Functional genomics of human brain development and implications for autism spectrum disorders
    Mark N. Ziats, Luke P. Grosvenor, Owen M. Rennert · 2015 · Translational Psychiatry
  34. Predicting chemotherapeutic drug combinations through gene network profiling
    Thi Thuy Trang Nguyen, Jacqueline Kia Kee Chua, Kwi Shan Seah, Seok Hwee Koo, Jie Yin Yee, Eugene Guorong Yang, Kim Kiat Lim, Shermaine Pang, Audrey Yuen, Louxin Zhang et al. · 2016 · Scientific Reports
  35. Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae
    Dimitris Kyriakou, Emmanouil Stavrou, Panayiota Demosthenous, Georgia Angelidou, Bryan-Joseph San Luis, Charles M. Boone, Vasilis J. Promponas, Antonis Kirmizis · 2016 · BMC Biology
  36. Using BEAN-counter to quantify genetic interactions from multiplexed barcode sequencing experiments
    Scott W. Simpkins, Raamesh Deshpande, Justin Nelson, Sheena Claire Li, Jeff S. Piotrowski, Henry N. Ward, Yoko Yashiroda, Hiroyuki Osada, Minoru Yoshida, Charles M. Boone et al. · 2019 · Nature Protocols
  37. SCRaMbLEing of a Synthetic Yeast Chromosome with Clustered Essential Genes Reveals Synthetic Lethal Interactions
    Peixia Wang, Hui Xu, Hao Li, Hebing Chen, Sijie Zhou, Fangfang Tian, Bing‐Zhi Li, Xiaochen Bo, Yi Wu, Ying‐Jin Yuan · 2020 · ACS Synthetic Biology
  38. Synthetic physical interactions map kinetochore regulators and regions sensitive to constitutive Cdc14 localization
    Guðjón Ólafsson, Peter Harold Thorpe · 2015 · Proceedings of the National Academy of Sciences
  39. Genetic profiling of protein burden and nuclear export overload
    Reiko Kintaka, Koji Makanae, Shotaro Namba, Hisaaki Kato, Keiji Kito, Shinsuke Ohnuki, Yoshikazu Ohya, Brenda Andrews, Charles M. Boone, Hisao Moriya · 2020 · eLife
  40. iSeq: A New Double-Barcode Method for Detecting Dynamic Genetic Interactions in Yeast
    Mia Jaffe, Gavin Sherlock, Sasha F. Levy · 2017 · G3 Genes Genomes Genetics
  41. A Bayesian non-parametric mixed-effects model of microbial growth curves
    Peter D. Tonner, Cynthia L. Darnell, Francesca M. L. Bushell, Peter A. Lund, Amy Schmid, Scott C. Schmidler · 2020 · PLoS Computational Biology
  42. Functional assessment of the “two-hit” model for neurodevelopmental defects in Drosophila and X. laevis
    Lucilla Pizzo, Micaela C. Lasser, Tanzeen Yusuff, Matthew Jensen, Phoebe Ingraham, Emily Huber, Mayanglambam Dhruba Singh, Connor Monahan, Janani S. Iyer, Inshya Desai et al. · 2021 · PLoS Genetics
  43. Tubulin isotypes optimize distinct spindle positioning mechanisms during yeast mitosis
    Emmanuel T. Nsamba, Abesh Bera, Michael Costanzo, Charles M. Boone, Mohan L. Gupta · 2021 · The Journal of Cell Biology
  44. A Lysine-Rich Region within Fungal BAG Domain-Containing Proteins Mediates a Novel Association with Ribosomes
    Jacob Verghese, Kevin A. Morano · 2012 · Eukaryotic Cell
  45. Comparative 3D Genome Structure Analysis of the Fission and the Budding Yeast
    Ke Qin Gong, Harianto Tjong, Xianghong Jasmine Zhou, Frank Alber · 2015 · PLoS ONE
  46. Yeast Systems Biology: Our Best Shot at Modeling a Cell
    Charles M. Boone · 2014 · Genetics
  47. A role for Mog1 in H2Bub1 and H3K4me3 regulation affecting RNAPII transcription and mRNA export
    Paula Oliete‐Calvo, Joan Serrano‐Quílez, Carme Nuño‐Cabanes, Maria E. Pérez-Martínez, Luis Miguel Mendes Soares, Bernhard Dichtl, Stephen Buratowski, José Enrique Pérez-Ortín, Susana Rodríguez‐Navarro · 2018 · EMBO Reports
  48. Links between critical proteins drive the controllability of protein interaction networks
    Stefan Wuchty, Toni A. Boltz, Hande Küçük‐McGinty · 2017 · PROTEOMICS
  49. Re-defining synthetic lethality by phenotypic profiling for precision oncology
    Yevhen A. Akimov, Tero A. Aittokallio · 2021 · Cell chemical biology
  50. Posterior Association Networks and Functional Modules Inferred from Rich Phenotypes of Gene Perturbations
    Xin Wang, Mauro A. A. Castro, Klaas W. Mulder, Florian M. Markowetz · 2012 · PLoS Computational Biology
  51. Predicting complex phenotype–genotype interactions to enable yeast engineering: Saccharomyces cerevisiae as a model organism and a cell factory
    Duygu Dikicioǧlu, Pınar Pir, Stephen G. Oliver · 2013 · Biotechnology Journal
  52. Mapping a diversity of genetic interactions in yeast
    Jolanda S. van Leeuwen, Charles M. Boone, Brenda Andrews · 2017 · Current Opinion in Systems Biology
  53. Mms1 and Mms22 stabilize the replisome during replication stress
    Jessica A. Vaisica, Anastasija Baryshnikova, Michael Costanzo, Charles M. Boone, Grant W. Brown · 2011 · Molecular Biology of the Cell
  54. Context-defined cancer co-dependency mapping identifies a functional interplay between PRC2 and MLL-MEN1 complex in lymphoma
    Xiao Chen, Yinglu Li, Fang Zhu, Xinjing Xu, Brian Estrella, Manuel A. Pazos, John T. McGuire, Dimitris Karagiannis, Varun Sahu, Mustafo Mustafokulov et al. · 2023 · Nature Communications
  55. Exploring the Molecular Basis of Antifungal Synergies Using Genome-Wide Approaches
    Ameeta Kishore Agarwal, Siddharth Tripathi, Tao Xu, Melissa Ruth Jacob, Xing‐Cong Li, Alice Mae Clark · 2012 · Frontiers in Microbiology
  56. Lithium Chloride Sensitivity in Yeast and Regulation of Translation
    Maryam Hajikarimlou, Kathryn Hunt, Grace Kirby, Sarah Takallou, Sasi Kumar Jagadeesan, Katayoun Omidi, Mohsen Hooshyar, Daniel. J. Burnside, Houman Moteshareie, Mohan Babu et al. · 2020 · International Journal of Molecular Sciences
  57. Gradients in gene essentiality reshape antibacterial research
    Andrew M. Hogan, Silvia T. Cardona · 2022 · FEMS Microbiology Reviews
  58. A Systems Biology Approach Reveals the Role of a Novel Methyltransferase in Response to Chemical Stress and Lipid Homeostasis
    Elena Lissina, Brian Y. Young, Malene L. Urbanus, Xue Li Guan, Jonathan D. Lowenson, Shawn S. Hoon, Anastasia Baryshnikova, Isabelle Riezman, Magali Michaut, Howard Riezman et al. · 2011 · PLoS Genetics
  59. Synthetic protein interactions reveal a functional map of the cell
    Lisa K Berry, Guðjón Ólafsson, Elena Ledesma-Fernández, Peter Harold Thorpe · 2016 · eLife
  60. Identifying Pseudomonas syringae Type III Secreted Effector Function via a Yeast Genomic Screen
    Amy Huei‐Yi Lee, D. Patrick Bastedo, Ji‐Young Youn, Timothy Lo, Maggie A. Middleton, Inga Kireeva, Jee Yeon Lee, Sara Sharifpoor, Anastasia Baryshnikova, Jianfeng Zhang et al. · 2018 · G3 Genes Genomes Genetics
  61. Mapping DNA damage‐dependent genetic interactions in yeast via party mating and barcode fusion genetics
    J. Javier Díaz-Mejía, Albi Celaj, Joseph C. Mellor, Atina G. Coté, Attila Balint, Brandon Ho, Pritpal Bansal, Fatemeh Shaeri, Marinella Gebbia, Jochen Weile et al. · 2018 · Molecular Systems Biology
  62. Protein kinase A controls yeast growth in visible light
    Mikael Molin, Katarina Logg, Kristofer Bodvard, Ken Peeters, Annabelle Forsmark, Friederike Roger, Anna Jörhov, Neha Mishra, Jean‐Marc Billod, Sabiha Amir et al. · 2020 · BMC Biology
  63. Association and dissociation between the mitochondrial Far complex and Atg32 regulate mitophagy
    Aleksei Innokentev, Kentaro Furukawa, Tomoyuki Fukuda, Tetsu Saigusa, Keiichi Inoue, Shun‐ichi Yamashita, Tomotake Kanki · 2020 · eLife
  64. Striatin-1 is a B subunit of protein phosphatase PP2A that regulates dendritic arborization and spine development in striatal neurons
    Daniel Li, Veronica Musante, Wen‐Liang Zhou, Marina R. Picciotto, Angus Clark Nairn · 2018 · Journal of Biological Chemistry
  65. Differential analysis of high-throughput quantitative genetic interaction data
    Gordon J. Bean, Trey E. Ideker · 2012 · Genome biology
  66. Budding Yeast: An Ideal Backdrop for In vivo Lipid Biochemistry
    Pushpendra Singh · 2017 · Frontiers in Cell and Developmental Biology
  67. A resource for functional profiling of noncoding RNA in the yeast Saccharomyces cerevisiae
    Steven Parker, Marcin G. Fraczek, Jian Wu, Sara Shamsah, Alkisti Manousaki, Kobchai Dungrattanalert, Rogério Alves de Almeida, Diego Estrada‐Rivadeneyra, Walid Omara, Daniela Delneri et al. · 2017 · RNA
  68. Reverse PCA, a Systematic Approach for Identifying Genes Important for the Physical Interaction between Protein Pairs
    Ifat Lev, Marina Volpe, Liron Goor, Nelly Levinton, Liach Emuna, Shay Ben‐Aroya · 2013 · PLoS Genetics
  69. Multiple Genetic Interaction Experiments Provide Complementary Information Useful for Gene Function Prediction
    Magali Michaut, Gary D. Bader · 2012 · PLoS Computational Biology
  70. The nucleolar protein Viriato/Nol12 is required for the growth and differentiation progression activities of the Dpp pathway during Drosophila eye development
    Joana Catarina Lima Marinho, Torcato Martins, Marta Neto, Fernando Casares, Paulo S. Pereira · 2013 · Developmental Biology
  71. Microfluidic genome-wide profiling of intrinsic electrical properties in Saccharomyces cerevisiae
    Michael D. Vahey, Laia Quirós Pesudo, J. Peter Svensson, Leona D. Samson, Joel Voldman B · 2013 · Lab on a Chip
  72. Ameliorating the Metabolic Burden of the Co-expression of Secreted Fungal Cellulases in a High Lipid-Accumulating Yarrowia lipolytica Strain by Medium C/N Ratio and a Chemical Chaperone
    Hui Wei, Wei Wang, Hal S. Alper, Qi Xu, Eric P. Knoshaug, Stefanie Van Wychen, Chien-Yuan Lin, Yonghua Luo, Stephen R. Decker, Michael E. Himmel et al. · 2019 · Frontiers in Microbiology
  73. Measuring genetic interactions in human cells by RNAi and imaging
    Christina Laufer, Bernd Fischer, Wolfgang K. Huber, Michael Boutros · 2014 · Nature Protocols
  74. Sensitivity of yeast to lithium chloride connects the activity of YTA6 and YPR096C to translation of structured mRNAs
    Maryam Hajikarimlou, Houman Moteshareie, Katayoun Omidi, Mohsen Hooshyar, Sarah Shaikho, Thomas David Daniel Kazmirchuk, Daniel. J. Burnside, Sarah Takallou, Narges Zare, Sasi Kumar Jagadeesan et al. · 2020 · PLoS ONE
  75. Points of view: Points of review (part 2)
    Bang Wong · 2011 · Nature Methods
  76. Predicting bioprocess targets of chemical compounds through integration of chemical-genetic and genetic interactions
    Scott W. Simpkins, Justin Nelson, Raamesh Deshpande, Sheena Claire Li, Jeff S. Piotrowski, Erin H. Wilson, Abraham Abera Gebre, Hamid Safizadeh, Reika Okamoto, Mami Yoshimura et al. · 2018 · PLoS Computational Biology
  77. Detecting genetic interactions using parallel evolution in experimental populations
    Kaitlin J. Fisher, Sergey Kryazhimskiy, Gregory I. Lang · 2019 · Philosophical Transactions of the Royal Society B Biological Sciences
  78. Using colony size to measure fitness in Saccharomyces cerevisiae
    James H. Miller, Vincent J. Fasanello, Ping Liu, Emery R. Longan, Carlos A. Botero, Justin C. Fay · 2022 · PLoS ONE
  79. A functional connectome: regulation of Wnt/TCF-dependent transcription by pairs of pathway activators
    Jamie Freeman, David W. Smith, Branko Latinkic, Kenneth Ewan, Lee J. Samuel, Massimo Zollo, Natascia Marino, Lorraine Tyas, Nick S. Jones, Trevor C. Dale · 2015 · Molecular Cancer
  80. Exploitation of genetic interaction network topology for the prediction of epistatic behavior
    Gregorio Alanis‐Lobato, Carlo Vittorio Cannistraci, Timothy Ravasi · 2013 · Genomics
  81. The strength of genetic interactions scales weakly with mutational effects
    Andrea Velenich, Jeff Gore · 2013 · Genome biology
  82. Synthetic Genetic Arrays: Automation of Yeast Genetics
    Elena Kuzmin, Michael Costanzo, Brenda Andrews, Charles M. Boone · 2016 · Cold Spring Harbor Protocols
  83. Interrogation of γ-tubulin alleles using high-resolution fitness measurements reveals a distinct cytoplasmic function in spindle alignment
    Kristian Shulist, Eric Yen, Susanne Kaitna, Allen Y. Leary, Alexandra Decterov, Debarun Gupta, Jackie Vogel · 2017 · Scientific Reports
  84. One-Cell Doubling Evaluation by Living Arrays of Yeast, ODELAY!
    Thurston Herricks, David J. Dilworth, Fred David Mast, Song Li, Jennifer J. Smith, Alexander V. Ratushny, John D. Aitchison · 2017 · G3 Genes Genomes Genetics
  85. Worm Perturb-Seq: massively parallel whole-animal RNAi and RNA-seq
    Hefei Zhang, Xuhang Li, Dongyuan Song, Onur Yukselen, Shivani Nanda, Alper Küçükural, Jingyi Jessica Li, Manuel G. Garber, Albertha J.M. Walhout · 2025 · Nature Communications
  86. The Networked Partial Correlation and Its Application to the Analysis of Genetic Interactions
    Alberto Roverato, Robert Castelo · 2016 · Journal of the Royal Statistical Society Series C (Applied Statistics)
  87. The structure balance of gene-gene networks beyond pairwise interactions
    Nastaran Allahyari, Amir Kargaran, Ali Hosseiny, Gholamreza Jafari · 2022 · PLoS ONE
  88. Yeast Phenomics: An Experimental Approach for Modeling Gene Interaction Networks that Buffer Disease
    John L. Hartman, Chandler Stisher, Darryl Alan Outlaw, Jingyu Guo, Najaf A. Shah, Dehua Tian, Sean M. Santos, John W. Rodgers, Richard White · 2015 · Genes
  89. The Role of Protein Interactions in Mediating Essentiality and Synthetic Lethality
    David Talavera, David L. Robertson, Simon C. Lovell · 2013 · PLoS ONE
  90. Network-assisted target identification for haploinsufficiency and homozygous profiling screens
    Sheng Wang, Jian Peng · 2017 · PLoS Computational Biology
  91. ‘Small volume—big problem’: culturing Yarrowia lipolytica in high-throughput micro-formats
    Ewelina Celińska, Maria Gorczyca · 2024 · Microbial Cell Factories
  92. Genome-wide conditional degron libraries for functional genomics
    Eduardo Gameiro, Karla A. Juárez-Núñez, Jia Jun Fung, Susmitha Shankar, Brian Luke, Anton Khmelinskii · 2024 · The Journal of Cell Biology
  93. ChemGAPP: a tool for chemical genomics analysis and phenotypic profiling
    Hannah M. Doherty, George Kritikos, Marco Galardini, Manuel Banzhaf, Danesh Moradigaravand · 2023 · Bioinformatics
  94. Noise reduction in genome-wide perturbation screens using linear mixed-effect models
    Danni Yu, John Danku, Ivan R. Baxter, Sungjin Kim, Olena K. Vatamaniuk, David E. Salt, Olga Vitek A · 2011 · Bioinformatics
  95. Endosomal trafficking and DNA damage checkpoint kinases dictate survival to replication stress by regulating amino acid uptake and protein synthesis
    Arta Ajazi, Christopher Bruhn, Ghadeer Shubassi, Chiara Lucca, Elisa Ferrari, Angela Cattaneo, Angela Bachi, Nicola Manfrini, Stefano Biffo, Emanuele Martini et al. · 2021 · Developmental Cell
  96. Global Linkage Map Connects Meiotic Centromere Function to Chromosome Size in Budding Yeast
    Anastasia Baryshnikova, Benjamin VanderSluis, Michael Costanzo, Chad L. Myers, S. Rita, Brenda Andrews, Charles M. Boone · 2013 · G3 Genes Genomes Genetics
  97. τ-SGA: synthetic genetic array analysis for systematically screening and quantifying trigenic interactions in yeast
    Elena Kuzmin, Mahfuzur Rahman, Benjamin VanderSluis, Michael Costanzo, Chad L. Myers, Brenda Andrews, Charles M. Boone · 2021 · Nature Protocols
  98. Functional Genomics Using the Saccharomyces cerevisiae Yeast Deletion Collections
    Corey Nislow, Lai Hong Wong, Amy Huei‐Yi Lee, Guri N. Giaever · 2016 · Cold Spring Harbor Protocols
  99. Dimensionality reduction methods for extracting functional networks from large‐scale CRISPR screens
    Arshia Zernab Hassan, Henry N. Ward, Mahfuzur Rahman, Maximilian Billmann, Yoonkyu Lee, Chad L. Myers · 2023 · Molecular Systems Biology
  100. Functional genomics in the study of yeast cell polarity: moving in the right direction
    Erin B. Styles, Ji‐Young Youn, Mojca Mattiazzi Ušaj, Brenda Andrews · 2013 · Philosophical Transactions of the Royal Society B Biological Sciences