Quantitative analysis of fitness and genetic interactions in yeast on a genome scale

BioGRID: a general repository for interaction datasets

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Functional Discovery via a Compendium of Expression Profiles

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Tackling the widespread and critical impact of batch effects in high-throughput data

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The Genetic Landscape of a Cell

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Global Mapping of the Yeast Genetic Interaction Network

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High-Quality Binary Protein Interaction Map of the Yeast Interactome Network

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An in Vivo Map of the Yeast Protein Interactome

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The BioGRID Interaction Database: 2008 update

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Modular epistasis in yeast metabolism

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Coordination of Growth Rate, Cell Cycle, Stress Response, and Metabolic Activity in Yeast

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Mechanisms of Haploinsufficiency Revealed by Genome-Wide Profiling in Yeast

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A comprehensive strategy enabling high-resolution functional analysis of the yeast genome

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A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein

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Conservation and Rewiring of Functional Modules Revealed by an Epistasis Map in Fission Yeast

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Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions

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A strategy for extracting and analyzing large-scale quantitative epistatic interaction data

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Systematic Mapping of Genetic Interaction Networks

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High-resolution yeast phenomics resolves different physiological features in the saline response

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Finding function: evaluation methods for functional genomic data

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Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes

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Synthetic Genetic Array (SGA) Analysis in Saccharomyces cerevisiae and Schizosaccharomyces pombe

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Elg1 forms an alternative RFC complex important for DNA replication and genome integrity

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Functional Maps of Protein Complexes from Quantitative Genetic Interaction Data

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Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks

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Epistatic buffering of fitness loss in yeast double deletion strains

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Retrograde transport on the COG railway

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Derivation of genetic interaction networks from quantitative phenotype data

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Far3 and Five Interacting Proteins Prevent Premature Recovery from Pheromone Arrest in the Budding Yeast Saccharomyces cerevisiae

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Epistasis analysis with global transcriptional phenotypes

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Constitutive Activation of the pH-Responsive Rim101 Pathway in Yeast Mutants Defective in Late Steps of the MVB/ESCRT Pathway

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Relationship of DFG16 to the Rim101p pH Response Pathway in Saccharomyces cerevisiae and Candida albicans

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Components of the ESCRT Pathway, DFG16 , and YGR122w Are Required for Rim101 To Act as a Corepressor with Nrg1 at the Negative Regulatory Element of the DIT1 Gene of Saccharomyces cerevisiae

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Systematic quantification of gene interactions by phenotypic array analysis

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The gene PPG encodes a novel yeast protein phosphatase involved in glycogen accumulation.

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Characterization of the Yeast Amphiphysins Rvs161p and Rvs167p Reveals Roles for the Rvs Heterodimer In Vivo

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Systems-level approaches for identifying and analyzing genetic interaction networks in Escherichia coli and extensions to other prokaryotes

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A VAST staging area for regulatory proteins

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A global genetic interaction network maps a wiring diagram of cellular function

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Evolution by gene loss

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Yeast: An Experimental Organism for 21st Century Biology

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Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress

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The Yeast Deletion Collection: A Decade of Functional Genomics

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Genetic Interactions in Cancer Progression and Treatment

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Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions

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Molecular mechanisms of epistasis within and between genes

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Systematic exploration of synergistic drug pairs

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The expanding scope of DNA sequencing

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Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndromePreprint

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Systematic analysis of complex genetic interactions

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Global Genetic Networks and the Genotype-to-Phenotype Relationship

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Hierarchical Modularity and the Evolution of Genetic Interactomes across Species

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STRIPAK Complexes: structure, biological function, and involvement in human diseases

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The Genomic Landscape of Compensatory Evolution

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An integrated approach to characterize genetic interaction networks in yeast metabolism

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Mapping of signaling networks through synthetic genetic interaction analysis by RNAi

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Exploring genetic suppression interactions on a global scale

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Functional Repurposing Revealed by Comparing S. pombe and S. cerevisiae Genetic Interactions

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SGAtools: one-stop analysis and visualization of array-based genetic interaction screens

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Systematic Functional Annotation and Visualization of Biological Networks

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Systems-level antimicrobial drug and drug synergy discovery

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Gene Essentiality Analyzed by <i>In Vivo</i> Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of <i>Candida albicans</i>

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Structure-Function Analysis of Core STRIPAK Proteins

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TheCellMap.org: A Web-Accessible Database for Visualizing and Mining the Global Yeast Genetic Interaction Network

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De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences

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Quantitative Genome-Wide Genetic Interaction Screens Reveal Global Epistatic Relationships of Protein Complexes in Escherichia coli

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Mapping genetic interactions in human cancer cells with RNAi and multiparametric phenotyping

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Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways

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Strategies for target identification of antimicrobial natural products

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Charting the genetic interaction map of a cell

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Gene duplication can impart fragility, not robustness, in the yeast protein interaction network

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Exploring whole-genome duplicate gene retention with complex genetic interaction analysis

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Genetic Interaction Networks: Toward an Understanding of Heritability

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A homologue of the human STRIPAK complex controls sexual development in fungi

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Genetic interaction networks: better understand to better predict

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Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell

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Quantitative genetic-interaction mapping in mammalian cells

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A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities

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The chaperone-binding activity of the mitochondrial surface receptor Tom70 protects the cytosol against mitoprotein-induced stress

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Regulation of Recombination and Genomic MaintenancePreprint

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Recent insights into the genotype–phenotype relationship from massively parallel genetic assays

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Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways

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Translation of Genotype to Phenotype by a Hierarchy of Cell Subsystems

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Unraveling the Biology of a Fungal Meningitis Pathogen Using Chemical Genetics

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Synthetic Genetic Array Analysis for Global Mapping of Genetic Networks in Yeast

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Mapping Genetic Interaction Networks in Yeast

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Synthetic Genetic Array (SGA) Analysis in Saccharomyces cerevisiae and Schizosaccharomyces pombe

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Synthetic Genetic Array AnalysisPreprint

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