Heritable genome editing in C. elegans via a CRISPR-Cas9 system
Friedland, Ari E, Tzur, Yonatan B, Esvelt, Kevin M, Colaiácovo, Monica P, Church, George M, Calarco, John A·2013·Nature Methods
Cited by (879)
Items 701–800 of 879
- Glycobiology of Caenorhabditis elegansKatharina Paschinger, Shi Yan, Nicola L. B. Pohl, Iain B. H. Wilson · 2021 · Elsevier eBooks
- Efficient genome editing in carnation (Dianthus caryophyllus) using the CRISPR/Cas9 systemXueqing Fu, Kexuan Tang · 2023 · Acta Horticulturae
- Low-temperature embryo incubation suppresses off-target mutagenesis during CRISPR-Cas9 genome editing in medaka (Oryzias latipes) and zebrafish (Danio rerio)Takashi Yamanaka, Akiko Sogo, Shingo Maegawa, Masato Kinoshita · 2025 · Transgenic Research
- C30F12.4 influences oogenesis, fat metabolism, and lifespan in C. elegansLu Wang, Fei Xu, Guishuan Wang, Xiaorong Wang, Ajuan Liang, Hefeng Huang, Fei Sun · 2016 · Protein & Cell
- Therapeutic Gene Editing in Muscles and Muscle Stem CellsMohammadsharif Tabebordbar, Jason K. W. Cheng, Amy J. Wagers · 2017 · Research and perspectives in neurosciences
- CRISPR/Cas9: Contemporary designer nucleases for efficient genome editing in phytopathogenic fungiDulanjalee Lakmali Harishchandra, KWT Chethana, W Zhang, QK Xing, JB Peng, S Brooks, KD Hyde, XH Li, JY Yan · 2021 · Current Research in Environmental & Applied Mycology
- [Advances in transcription activator-like effectors--a review].Yu Tang, Lisha Li, Jun Lin · 2015 · PubMed
- CRISPR-Cas9 Genome Editing in Human Cell Lines with Donor Vector Made by Gibson AssemblyNirakar Sahoo, Victoria Cuello, Shreya Udawant, Carl Litif, Julie A. Mustard, Megan E. Keniry · 2020 · Methods in molecular biology
- Fast, Versatile and Quantitative Annotation of Complex ImagesKathleen Bates, Shen Jiang, Ruth Bates, Shivesh Chaudhary, Emily Jackson, Melinda Jue, Erin N. McCaskey, Daniel Goldman, Hang Lu · 2019 · BioTechniques
- The Amyloid Precursor-like Protein APL-1 Regulates Axon RegenerationLewie Zeng, Rachid M. El Bejjani, Marc Hammarlund · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Expanding the CRISPR/Cas toolkit: applications in proteomics and theranosticsAshwini Punde, Saurabh Dey, Riya Pandire, Arindam Bhattacharjee, Chinmoy Patra · 2025 · Frontiers in Bioengineering and Biotechnology
- The Caenorhabditis Genetics Center Curated Special Collections: a guide to protein degradation systemsJordan D. Ward, David J. Reiner, Aric L. Daul, Ann E. Rougvie · 2026 · Genetics
- A simple strategy for addition of degron tags to endogenous genes harboring prior insertions of fluorescent protein.Razan A. Fakieh, Tam Duong, You Wu, Neal R. Rasmussen, David J. Reiner · 2022 · PubMed Central
- Validation of endogenous U6 promoters for expanding the CRISPR toolbox in Nicotiana tabacumPan Luo, Si‐Yuan Li, Lulu Li, Yanyan Li, Ying Qiao, Xianzhi Wu, Meiling Wu, Zhihao Song, Yong Yang, Ji Feng et al. · 2024 · In Vitro Cellular & Developmental Biology - Plant
- Construction of a sensitive pyrogen‐testing cell model by site‐specific knock‐in of multiple genesRuobi Hu, Hui zi Li, Zhen Lei, Qing Han, Xiuyan Yu, Na Zhou, Xuehui Zhang, Yiqing Mao, Xi Wang, David M. Irwin et al. · 2019 · Biotechnology and Bioengineering
- Mutation Mapping and Identification by Whole-Genome SequencingHarold E. Smith · 2022 · Methods in molecular biology
- Visualizing Phagocytic Cargo In Vivo from Engulfment to Resolution in Caenorhabditis elegansGholamreza Fazeli, Julia Frondoni, Shruti Kolli, Ann Marie Wehman · 2023 · Methods in molecular biology
- Semantic representation of neural circuit knowledge in Caenorhabditis elegansSharan J. Prakash, Kimberly M. Van Auken, David P. Hill, Paul W. Sternberg · 2023 · Brain Informatics
- Mouse modeling of familial human SYCE1 c.197-2A>G splice site mutation leads to meiotic recombination failure and non-obstructive azoospermiaOmar Ignacio García-Martínez, Adriana Geisinger, Eliana de los Santos, Federico F. Santiñaque, Gustavo A. Folle, Jorge Luis Pórfido, María Noel Meikle, Geraldine Schlapp, Martina Crispo, Ricardo Benavente et al. · 2025 · Molecular Human Reproduction
- Gene delivery using viral vectorsDeepa H. Patel, Dipali R. Talele, Chitrali Talele · 2025 · Elsevier eBooks
- CRISPR-Cas: the effective immune systems in the prokaryotesYalda Vasebi, Reza Khakvar · 2014 · International journal of molecular and clinical microbiology
- The CRISPR-Cas9 System: A New Dawn in Gene EditingNurul Husna Mohamed Saleem · 2014 · OMICS Journal of Radiology
- Microbial genome engineering for promoting health and understanding diseaseTamás Fehér, Zsuzsa Györfy · 2015 · Repository of the Academy's Library (Library of the Hungarian Academy of Sciences)
- Procedures for Generating CRISPR Mutants with Novel Spacers Acquired from Viruses or PlasmidsMarie-Ève Dupuis, Rodolphe Barrangou, Sylvain Moineau · 2015 · Methods in molecular biology
- Inactivity periods and postural change speed can explain atypical postural change patterns of Caenorhabditis elegans mutantsTsukasa Fukunaga, Wataru Iwasaki · 2017 · BMC Bioinformatics
- Mathematical and computational analysis of CRISPR Cas9 sgRNA off-target homologiesMichael Zhou, Daisy Li, Xiaoli Huan, Josehph Manthey, Ekaterina Lioutikova, Hong Zhou · 2016 · IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
- OUP accepted manuscriptSelma Souf · 2016 · Bioscience Horizons The International Journal of Student Research
- Mathematical and computational analysis of CRISPR Cas9 sgRNA off-target homologiesMichael Zhou, Daisy Li, Xiaoli Huan, Joseph Manthey, Ekaterina Lioutikova, Hong Zhou · 2017 · International Journal of Biomathematics
- In vivo labeling of endogenous genomic loci in C. elegans using CRISPR/dCas9Nadin Memar, Aditya Sethi, Sebastian Luehr, Eric J. Lambie, Barbara Conradt · 2022 · PubMed Central
- MosSCI‐mediated exogenous gene expression is modulated by genomic positioningYuzhi Chen, Volker Manfred Arlt, Stephen Richard Stürzenbaum · 2023 · Biotechnology Journal
- Electron microscopy studies of Type III CRISPR machines in Sulfolobus solfataricusGiuseppe Cannone, Mariam T. Webber-Birungi, Laura Spagnolo · 2013 · Biochemical Society Transactions
- Emerging Technologies in the Analysis of C. elegans Nicotinic Acetylcholine ReceptorsAlison Philbrook, Michael M. Francis · 2016 · Neuromethods
- CRISPR–Cas9‐mediated mutation revealed BSPH2 protein is dispensable for male fertilityMarzieh Eskandari Shahraki, Bruno Prud’homme, P. Manjunath · 2018 · Molecular Reproduction and Development
- Design of Repair Templates for CRISPR-Cas9-Triggered Homologous Recombination in Caenorhabditis elegansHyun‐Min Kim, Xiaojuan Zhang · 2021 · Springer protocols handbooks/Springer protocols
- Allelic spectrum of the RNA guided CRISPR/Cas9 DNA repair events at PAM associated trinucleotide repeat (NGG)n in Caenorhabditis elegans.Wadim J Kapulkin · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
- Normal spindle positioning in the absence of EBPs and dynein plus-end tracking in C. elegansRuben Schmidt, Anna S. Akhmanova, Sander van den Heuvel · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
- Natural Genetic Variation in a Multigenerational Phenotype in C. ElegansLise Frézal, Émilie Demoinet, Christian Braendle, Eric Alexander Miska, Marie-Anne FFlix · 2018 · SSRN Electronic Journal
- Confirming the Pro-longevity Effects of H3K4me3-deficient set-2 Mutants in Extending Lifespan in C. elegansCarlos G. Silva-García, William B. Mair · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Cancer Therapy with CRISPR/Cas9: Prospects and ChallengesMuhammad Fahad Chaudhary, Unsa Saleem, Samia Khan, Rabiya Khan, Muhammad Asim, Fakhra Azam, Mariam Sharif, Zainab Zainab, Ali Abbas Dilawar, Muhammad Jehanzaib · 2021 · International Journal of Environment Agriculture and Biotechnology
- Revolutionizing animal husbandry: Breakthroughs in gene editing delivery systemsYuan Liu, Xue Bai, Xue Feng, Shuang Liu, Yamei Hu, Hongen Chu, Lingkai Zhang, Bei Cai, Yun Ma · 2024 · Gene
- SunTag-Based Single-Molecule Translation Imaging in Caenorhabditis elegansElise van der Salm, Stefanos Kontogiannis, Suzan Ruijtenberg · 2025 · BIO-PROTOCOL
- Advances in sleep research based on the Caenorhabditis elegans: an intestinal microbiota perspective and cutting-edge technology applicationsWan-Qi Zhang, Xiao-Lin Li, Ruipeng Xu, Yu-Long Li, Pengfei Hu, Ka-Hing Wong, Zhongyang Lin, Qiong-Qiong Yang, Bo‐Bo Zhang · 2026 · Sleep Medicine Reviews
- Caenorhabditis elegans: A Model System for Accelerating Studies on Bacillus thuringiensis Infection in InsectsMing Sun, Jianwei Shi, Alejandra Bravo · 2026 · Annual Review of Entomology
- RNA Interference as an Approach to Functional Genomics Genetic Manipulation of Opisthorchis viverriniThewarach Laha, Paul J. Brindley, Watcharapol Suyapoh, Sutas Suttiprapa · 2018 · Advances in Parasitology/Advances in parasitology
- Activating the C. elegans egg: Molecular players, current knowledge, and unanswered questionsAimee Jaramillo-Lambert, Amber R. Krauchunas · 2025 · Current topics in developmental biology/Current Topics in Developmental Biology
- Epitope-based labeling for improved live-imaging of endogenous proteins in C. elegansElise van der Salm, Mette Schroeder, Loes B. Steller, Stephanie I. Miller, Amelie Scheper, Gwen Nowee, Erik E. Griffin, Suzan Ruijtenberg · 2026 · G3 Genes Genomes Genetics
- FLInt 2.0: robust and customizable single-shot integration in C. elegansNawaphat Malaiwong, Porhathai Malaiwong, Chloe Kim, Michael O'Donnell · 2026 · G3 Genes Genomes Genetics
- Manipulation of epigenetic factors and the DNA repair machinery for improving the frequency of plant transformationAndriy Bilichak, Igor Kovalchuk · 2013 · Biocatalysis and Agricultural Biotechnology
- Using the CRISPR/Cas9 system to target cis-regulatory sequences in C. elegansMichalis Barkoulas, Aurélien Richaud, Marie‐Anne Félix · 2014
- Mapping paths: new approaches to dissect eukaryotic signaling circuitryNebibe Mutlu, Anuj Kumar · 2016 · F1000Research
- Application of targeted genome-editing technologies in Caenorhabditis elegansXuezhu Feng, Xiangyang Chen, Shouhong Guang · 2018 · Scientia Sinica Vitae
- Second Generation Genome Editing Technologies in Drug DiscoveryThomas Malcolm, David A. Mitchell, Niraj Muni · 2020 · Elsevier eBooks
- CRISPeering: Bioengineering the Host Cells through CRISPRCas9 Genome Editing System as the Next-generation of Cell FactoriesMohammad Hossein Morowvat · 2021 · Recent Patents on Biotechnology
- CRISPR–Cas systems in bioactive peptide researchKhushwant Singh Bhullar, Nan Shang, Jianping Wu · 2021 · Elsevier eBooks
- A role for worm cutl-24 in background- and parent-of-origin-dependent ER stress resistanceWenke Wang, Anna G. Flury, Andrew T. Rodriguez, Jennifer L. Garrison, Rachel B. Brem · 2022 · BMC Genomics
- An endomembrane zinc transporter negatively regulates systemic RNAi in Caenorhabditis elegansKatsufumi Dejima, Rieko Imae, Yuji Suehiro, Keita Yoshida, Shohei Mitani · 2023 · iScience
- A nematode model to evaluate microdeletion phenotype expressionKatianna R. Antkowiak, Peren Coskun, Sharon T. Noronha, Davide Tavella, Francesca Massi, Sean P. Ryder · 2023 · G3 Genes Genomes Genetics
- PBRM-1/PBAF-regulated genes in a multipotent progenitor in Caenorhabditis elegansLaura D. Mathies, Andrew C. Kim, Evan M. Soukup, Alan’da E. Thomas, Jill C. Bettinger · 2023 · G3 Genes Genomes Genetics
- A cytidine deaminase regulates axon regeneration by modulating the functions of the Caenorhabditis elegans HGF/plasminogen family protein SVH-1Tatsuhiro Shimizu, Takafumi Nomachi, Kunihiro Matsumoto, Naoki Hisamoto · 2024 · PLoS Genetics
- CRISPR/Cas9 for Genome Engineering: the Next Genomic RevolutionYaochun Zhang, Wee Song Yeo, Kar Hui Ng, Hui‐Kim Yap · 2015 · Journal of Biochemistry and Molecular Biology Research
- Establishment of Time- and Cell-Specific RNAi in Caenorhabditis elegansMasayuki Hamakawa, Takaaki Hirotsu · 2016 · Methods in molecular biology
- A CRISPR View of Biological MechanismsEduardo Martinez, Lilia Sanchez, Neftalí Vázquez, Rebecca Marks, Raechel Cedillo, Christa Respondek, Martin Holguin, Holguin, Michael W. Persans, Megan E. Keniry · 2016 · Discoveries
- Noncanonical meiosis in the nematode Caenorhabditis elegans as a model for studying the molecular bases of the homologous chromosome synapsis, crossing over, and segregationYu. F. Bogdanov · 2017 · Russian Journal of Genetics
- General Genetic StrategiesLouise M. Steele, Philip G. Morgan · 2018 · Methods in enzymology on CD-ROM/Methods in enzymology
- GTSF-1 is required for the formation of a functional RNA-dependent RNA Polymerase complex in C. elegansMiguel Vasconcelos Almeida · 2018 · Data Archiving and Networked Services (DANS)
- CRISPR-Cas Technology as a Tool to Create Animal Models for Biomedical ResearchAbhiraami Kannan-Sundhari, Shalini Kamu Reddy, Katherina Walz, Channabasavaiah B. Gurumurthy, Rolen M. Quadros · 2019 · Elsevier eBooks
- Cell Polarity in One-Cell C. elegans Embryos: Ensuring an Accurate and Precise Spatial Axis During DevelopmentMartin Mikl, Carrie R. Cowan · 2015 · Springer eBooks
- A Fusion PCR Method for Expressing Genetic Tools in C. elegansEduard Bokman, Yifat Eliezer, Alon Zaslaver · 2022 · Methods in molecular biology
- New alleles of the SWI/SNF chromatin remodeling complex gene phf-10Laura D. Mathies, GinaMari G. Blackwell, Jill C. Bettinger · 2022 · PubMed Central
- Meiotic prophase regulation and achiasmate chromosome segregation in Caenorhabditis elegansChristina M. Glazier · 2015 · eScholarship (California Digital Library)
- CRISPR-Cas9-mediated protein tagging in human cells for RESOLFT nanoscopy and the analysis of mitochondrial prohibitinsMichael Ratz · 2016
- CRISPRs in the Human MicrobiomeYuzhen Ye · 2013 · Springer eBooks
- Hox3 duplication and divergence in the LepidopteraLuca Livraghi · 2017 · Radar (Oxford Brookes University)
- DREAM Interrupted: Severing LIN-35-MuvB association in Caenorhabditis elegans impairs DREAM function but not its chromatin localizationPaul D. Goetsch, Susan Strome · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Functional genomics in Schizophyllum communePeter Jan Vonk · 2022
- Cas Variants Increased the Dimension of the CRISPR Tool KitSameer Dixit, Akanchha Shukla, Mahendra Pawar, Jyothilakshmi Vadassery · 2023 · Wiley eBooks
- The forkhead transcription factor FKH-7/FOXP acts in chemosensory neurons to regulate developmental decision-makingCynthia M. Chai, Seth R. Taylor, Carsten H. Tischbirek, Wan-Rong Wong, Long Cai, David M. Miller, Paul W. Sternberg · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- GPCR-Gαq Signaling Drives Adaptive Resistance to MEK Inhibition in BRAF-Mutant MelanomaJingyi Ke, Zi Wang, Zhengyang Guo, Guangshuo Ou, Wei Li · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Molecular analyses of visual processing and learning in honey beesHaiyang Geng · 2022
- The use of natural genetic variation in Caenorhabditis elegans to identify novel polymorphisms that can confer benzimidazole resistance in nematodesSharmilah Luthfia Jezmine Latheef · 2014 · Libraries and Cultural Resources (University of Calgary)
- Engineered Nucleases Lead to Genome Editing Revolution in RatsKazuto Yoshimi, Takehito Kaneko, Birger Voigt, Tomoji Mashimo · 2014 · Springer eBooks
- Genome Editing in NematodeTakuma Sugi · 2014 · Springer eBooks
- Glycosaminoglycan Biosynthesis in ZebrafishBeata Filipek‐Górniok · 2015 · KTH Publication Database DiVA (KTH Royal Institute of Technology)
- A quantitative analysis to unveil specific binding proteins for bioactive compoundsTomonori Arai, Masayoshi Uehata, Hiroyuki Akatsuka, Tsutomu Kamiyama · 2012 · Protein Engineering Design and Selection
- Mechanism and engineering of CRISPR-associated endonucleasesSamuel H. Sternberg · 2014 · eScholarship (California Digital Library)
- Challenges and Opportunities for Synthetic Biology in IndiaSingh Pk · 2014 · Current Synthetic and Systems Biology
- The Role of Sox4 in Regulating Choroid Fissure Closure and Retinal NeurogenesisWen, Wen · 2016 · UKnowledge (University of Kentucky)
- A Genetic Test of a Model for Two Activities of Fushi Tarazu Protein in Drosophila MelanogasterAlaa Briek · 2016 · Scholarship@Western (Western University)
- Recent Advances in the Enabling Technologies for Synthetic BiologyYinhua Lü, Xiaoli Xue, Lei LI, Zhongjun Qin, Weihong Jiang · 2015 · Scientia Sinica Vitae
- Endocytic recycling and regulation of the early-to-recycling endosome transitionLiu, Ou · 2015
- The -Omics RaceAurelio Ciancio · 2016 · Springer eBooks
- Genome Editing in Stem CellsLeon Tejwani, Cleber A. Trujillo, Charles A. Thomas, Alysson Renato Muotri · 2016 · Springer eBooks
- Studies in Caenorhabditis elegans Olfaction and LearningDaniel M. Merritt · 2016 · TSpace (University of Toronto)
- Characterization of nuclear envelope proteins NPP-16 and LEM-2 and identification of interaction partnersAdela Morales-Martínez · 2013 · DIGITAL.CSIC (Spanish National Research Council (CSIC))
- Modeling Disease In Vivo WithEleanor Dow · 2015
- The Biosynthesis of Ascarosides in Caenorhabditis elegansAllison E. Akagi · 2017 · CaltechTHESIS (California Institute of Technology)
- How to Clear HBV cccDNA: CRISPR/Cas9 Might Be PromisingYan Qiu, Ying Liu, Wen Ren, Jing Ren · 2017 · Preprints.org
- 基于CRISPR/Cas9基因编辑技术的人类遗传疾病基因治疗相关研究进展可 门, 醒妹 段, 阳 杨, 于全 魏 · 2017 · Scientia Sinica Vitae
- Неканонический мейоз у нематоды Caenorhabditis elegans как модель для изучения молекулярных основ синапсиса, кроссинговера и сегрегации гомологичных хромосом, "Генетика"Ю.Ф. Богданов · 2017 · Генетика
- Mechanism of Semaphorin-Plexin signaling in synaptic pattern formation in Caenorhabditis elegansXi Chen · 2018 · cIRcle (University of British Columbia)