The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Comparison of Cas9 activators in multiple species
Open accessAbstract
Several programmable transcription factors exist based on the versatile Cas9 protein, yet their relative potency and effectiveness across various cell types and species remain unexplored. Here, we compare Cas9 activator systems and examine their ability to induce robust gene expression in several human, mouse, and fly cell lines. We also explore the potential for improved activation through the combination of the most potent activator systems, and we assess the role of cooperativity in maximizing gene expression.
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Cites
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Cited by
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Metadata
- Authors
- Chavez, A., Tuttle, M., Pruitt, B. W., Ewen-Campen, B., Chari, R., Ter-Ovanesyan, D., Haque, S. J., Cecchi, R. J., Kowal, E. J. K., Buchthal, J., Housden, B. E., Perrimon, N., Collins, J. J., & Church, G.
- Venue
- Nature Methods
- Published
- 2016-05-23
- Volume
- 13
- Issue
- 7
- Pages
- 563-567
- ISSN
- 1548-7091 (ISSN-L)
- 1548-7105
- OpenAlex
- W2400411104
- Cited by
- 519
- References
- 17
- FWCI
- 27.09
- Type
- journal article
- Language
- en
- Open access
- green
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- Chavez, A., Tuttle, M., Pruitt, B. W., Ewen-Campen, B., Chari, R., Ter-Ovanesyan, D., Haque, S. J., Cecchi, R. J., Kowal, E. J. K., Buchthal, J., Housden, B. E., Perrimon, N., Collins, J. J., & Church, G. (2016). Comparison of Cas9 activators in multiple species. Nature Methods. https://doi.org/10.1038/nmeth.3871
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