The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Convolutional neural networks for automated annotation of cellular cryo-electron tomograms
Open accessAbstract
Cellular electron cryotomography offers researchers the ability to observe macromolecules frozen in action in situ, but a primary challenge with this technique is identifying molecular components within the crowded cellular environment. We introduce a method that uses neural networks to dramatically reduce the time and human effort required for subcellular annotation and feature extraction. Subsequent subtomogram classification and averaging yield in situ structures of molecular components of interest. The method is available in the EMAN2.2 software package.
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LeCun, Y., Bengio, Y., & Hinton, G. (2015) · Nature · doi:10.1038/nature14539 · Cited by 84,126
Improving neural networks by preventing co-adaptation of feature detectors
Hinton, G. E., Srivastava, N., Krizhevsky, A., Sutskever, I., & Salakhutdinov, R. R. (2012) · arXiv · doi:10.48550/arxiv.1207.0580 · Cited by 6,382
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Riguet, N., Mahul-Mellier, A.-L., Maharjan, N., Burtscher, J., Croisier, M., Knott, G., Hastings, J., Patin, A., Reiterer, V., Farhan, H., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-26684-z · Cited by 118
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Brasch, J., Goodman, K. M., Noble, A. J., Rapp, M., Mannepalli, S., Bahna, F., Dandey, V. P., Bepler, T., Berger, B., Maniatis, T., et al. (2019) · Nature · doi:10.1038/s41586-019-1089-3 · Cited by 99
Vimentin filaments integrate low-complexity domains in a complex helical structure
Eibauer, M., Weber, M. S., Kronenberg-Tenga, R., Beales, C. T., Boujemaa-Paterski, R., Turgay, Y., Sivagurunathan, S., Kraxner, J., Köster, S., Goldman, R. D., et al. (2024) · Nature Structural & Molecular Biology · doi:10.1038/s41594-024-01261-2 · Cited by 87
Microtubule architecture in vitro and in cells revealed by cryo-electron tomography
Atherton, J., Stouffer, M., Francis, F., & Moores, C. A. (2018) · Acta Crystallographica Section D Structural Biology · doi:10.1107/s2059798318001948 · Cited by 85
Metadata
- Authors
- Chen, M., Dai, W., Sun, S. Y., Jonasch, D., He, C. Y., Schmid, M. F., Chiu, W., & Ludtke, S. J.
- Venue
- Nature Methods
- Published
- 2017-08-28
- Volume
- 14
- Issue
- 10
- Pages
- 983-985
- ISSN
- 1548-7091 (ISSN-L)
- 1548-7105
- OpenAlex
- W2580555377
- Cited by
- 398
- References
- 2
- FWCI
- 11.01
- Type
- journal article
- Language
- en
- Open access
- green
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