High-resolution insertion-site analysis by linear amplification-mediated PCR (LAM-PCR)

Cited by (328)

Items 101–200 of 328

1. Bioinformatic Clonality Analysis of Next-Generation Sequencing-Derived Viral Vector Integration Sites
   Anne Arens, Jens-Uwe Appelt, Cynthia C. Bartholomae, Richard Gabriel, Anna Paruzynski, Derek Gustafson, Nathalie Cartier, Patrick R. Aubourg, Annette Deichmann, Hanno Glimm et al. · 2012 · Human Gene Therapy Methods
2. Lentivirus-induced ‘Smart’ dendritic cells: Pharmacodynamics and GMP-compliant production for immunotherapy against TRP2-positive melanoma
   Bala Sai Sundarasetty, Lucas Chan, D Darling, G Giunti, Farzin Farzaneh, Florian Schenck, Sonja Naundorf, Klaus Kuehlcke, Eliana Ruggiero, Manfred Schmidt et al. · 2015 · Gene Therapy
3. Stem Cell Gene Therapy for Fanconi Anemia: Report from the 1st International Fanconi Anemia Gene Therapy Working Group Meeting
   Jakub Tolar, Jennifer E. Adair, Michael Nicolas Antoniou, Cynthia C. Bartholomae, Pamela Sue Becker, Bruce R. Blazar, Juan Antonio Bueren, Thomas Carroll, Marina Cavazzana, D. Wade Clapp et al. · 2011 · Molecular Therapy
4. Lentivirus-mediated Reprogramming of Somatic Cells in the Absence of Transgenic Transcription Factors
   Nicole M. Kane, Ali Nowrouzi, Sayandip Mukherjee, Michael P. Blundell, Jenny A. Greig, Wai Kwong Lee, Miles D. Houslay, Graeme Milligan, Joanne C. Mountford, Christof V. Kalle et al. · 2010 · Molecular Therapy
5. Succession of transiently active tumor‐initiating cell clones in human pancreatic cancer xenografts
   C. Ball, F. Oppel, K. R. Ehrenberg, Taronish D. Dubash, S. Dieter, Christopher M. Hoffmann, U. Abel, F. Herbst, M. Koch, J. Werner et al. · 2017 · EMBO Molecular Medicine
6. Analyzing the Genotoxicity of Retroviral Vectors in Hematopoietic Cell Gene Therapy
   L. Biasco, M. Rothe, H. Büning, A. Schambach · 2017 · Molecular Therapy: Methods & Clinical Development
7. No Evidence for Clonal Selection Due to Lentiviral Integration Sites in Human Induced Pluripotent Stem Cells
   Thomas Winkler, Amy Rose Cantilena, Jean‐Yves Métais, Xiuli Xu, Anh‐Dao Nguyen, Bhavesh R. Borate, Jessica Antosiewicz‐Bourget, Tyra G. Wolfsberg, James Alexander Thomson, Cynthia E. Dunbar · 2010 · Stem Cells
8. Integration Mapping of piggyBac-Mediated CD19 Chimeric Antigen Receptor T Cells Analyzed by Novel Tagmentation-Assisted PCR
   Motoharu Hamada, Nobuhiro Nishio, Yusuke Okuno, Satoshi Suzuki, Nozomu Kawashima, Hideki Muramatsu, Shoma Tsubota, Matthew H. Wilson, Daisuke Morita, Shinsuke Kataoka et al. · 2018 · EBioMedicine
9. Correction of Murine SCID-X1 by Lentiviral Gene Therapy Using a Codon-optimized IL2RG Gene and Minimal Pretransplant Conditioning
   Marshall W. Huston, Niek Peter van Til, Trudi P. Visser, Shazia Arshad, Martijn H. Brugman, Claudia Cattoglio, Ali Nowrouzi, Yuedan Li, Axel Schambach, Manfred Schmidt et al. · 2011 · Molecular Therapy
10. High-Definition Mapping of Retroviral Integration Sites Defines the Fate of Allogeneic T Cells After Donor Lymphocyte Infusion
    Claudia Cattoglio, Giulietta Maruggi, Cynthia C. Bartholomae, Nirav Malani, Danilo Pellin, Fabienne Cocchiarella, Zulma Irene Magnani, Fabio Ciceri, Alessandro Ambrosi, Christof V. Kalle et al. · 2010 · PLoS ONE
11. An emerging role for cyclic dinucleotide phosphodiesterase and nanoRNase activities in Mycoplasma bovis: Securing survival in cell culture
    Xifang Zhu, Éric Baranowski, Yaqi Dong, Xixi Li, Zhiyu Hao, Gang Zhao, Hui Zhang, Doukun Lu, Muhammad Asif Rasheed, Yingyu Chen et al. · 2020 · PLoS Pathogens
12. Preclinical Testing of the Safety and Tolerability of Lentiviral Vector–Mediated Above-Normal Alpha-L-Iduronidase Expression in Murine and Human Hematopoietic Cells Using Toxicology and Biodistribution Good Laboratory Practice Studies
    I. Visigalli, Stefania Delai, F. Ferro, Francesca Cecere, M. Vezzoli, F. Sanvito, F. Chanut, F. Benedicenti, Giulio Spinozzi, R. Wynn et al. · 2016 · Human Gene Therapy
13. Clonal tracking using embedded viral barcoding and high-throughput sequencing
    Charles S. Bramlett, Jiang Du, Anna Nogalska, Jiya Eerdeng, Jorge L. Contreras, Rong Lu · 2020 · Nature Protocols
14. Genome-wide Specificity of Highly Efficient TALENs and CRISPR/Cas9 for T Cell Receptor Modification
    Friederike Knipping, Mark J. Osborn, Karl Petri, Jakub Tolar, Hanno Glimm, Christof V. Kalle, Manfred Schmidt, Richard Gabriel · 2017 · Molecular Therapy — Methods & Clinical Development
15. VISPA2: a scalable pipeline for high-throughput identification and annotation of vector integration sites
    Giulio Spinozzi, Andrea Calabria, Stefano Brasca, Stefano Beretta, Ivan Merelli A, Luciano Milanesi, Eugenio Montini · 2017 · BMC Bioinformatics
16. Long-Term Episomal Transgene Expression from Mitotically Stable Integration-Deficient Lentiviral Vectors
    Hanna Kymäläinen, Jens Uwe Appelt, Frank Anton Giordano, Angela F. Davies, Caroline Mackie Ogilvie, SG Ahmed, Stephanie Laufs, Manfred Schmidt, Juergen Bode, Rafael J. Yáñez‐Muñoz et al. · 2014 · Human Gene Therapy
17. DNA enrichment approaches to identify unauthorized genetically modified organisms (GMOs)
    Alfred J. Arulandhu, Jeroen P. van Dijk, David Dobnik, Arne Holst‐Jensen, Jianxin Shi, Jana Žel, E.J. Kok · 2016 · Analytical and Bioanalytical Chemistry
18. Mbov_0503 Encodes a Novel Cytoadhesin that Facilitates Mycoplasma bovis Interaction with Tight Junctions
    Xifang Zhu, Yaqi Dong, Éric Baranowski, Xixi Li, Gang Zhao, Zhiyu Hao, Hui Zhang, Yingyu Chen, Changmin Hu, Huanchun Chen et al. · 2020 · Microorganisms
19. Identifying viral integration sites using SeqMap 2.0
    Troy Hawkins, Jessica Dantzer, Brandon J. Peters, Mary C. Dinauer, Keithanne Mockaitis, Sean David Mooney, Kenneth G. Cornetta · 2011 · Bioinformatics
20. Ribosomal DNA integrating rAAV-rDNA vectors allow for stable transgene expression.
    L. Lisowski, Ashley Lau, Zhongya Wang, Yue Zhang, Fei-Jie Zhang, Markus Grompe, Mark A. Kay · 2012 · Molecular Therapy
21. Microbial single-strand annealing proteins enable CRISPR gene-editing tools with improved knock-in efficiencies and reduced off-target effects
    Chengkun Wang, Jason K. W. Cheng, Qianhe Zhang, Nicholas W. Hughes, Qiong Xia, Monte M. Winslow, Le Cong · 2020 · Nucleic Acids Research
22. GENE-IS: Time-Efficient and Accurate Analysis of Viral Integration Events in Large-Scale Gene Therapy Data
    Saira Afzal, Stefan Wilkening, Christof V. Kalle, Manfred Schmidt, Raffaele Fronza · 2016 · Molecular Therapy — Nucleic Acids
23. Lentiviral Hematopoietic Stem Cell Gene Therapy Corrects Murine Pompe Disease
    Merel Stok, Helen de Boer, Marshall W. Huston, Edwin H. Jacobs, Onno Roovers, Trudi P. Visser, Holger Jahr, Dirk Jan Duncker, Elza Dianne van Deel, Arnold J.J. Reuser et al. · 2020 · Molecular Therapy — Methods & Clinical Development
24. RAISING is a high-performance method for identifying random transgene integration sites
    Yusaku Wada, Tomoo Sato, Hiroo Hasegawa, Takahiro Matsudaira, Naganori Nao, Ariella L. G. Coler-Reilly, Tomohiko Tasaka, Shunsuke Yamauchi, Tomohiro Okagawa, Haruka Momose et al. · 2022 · Communications Biology
25. Integrase-Deficient Lentiviral Vectors Mediate Efficient Gene Transfer to Human Vascular Smooth Muscle Cells with Minimal Genotoxic Risk
    He Chick, A. Nowrouzi, R. Fronza, R. Mcdonald, N. Kane, R. Alba, C. Delles, W. Sessa, M. Schmidt, A. Thrasher et al. · 2012 · Human Gene Therapy
26. Therapeutic expression of human clotting factors IX and × following adeno‐associated viral vector‐mediated intrauterine gene transfer in early‐gestation fetal macaques
    Jerry Kok Yen Chan, Irene Gil-Fariña, Nuryanti Binti Johana, Cecilia Rosales, Yi Wan Tan, Jessika Ceiler, Jenny McIntosh, Bryan Emmett Ogden, Simon N. Waddington, Manfred Schmidt et al. · 2018 · The FASEB Journal
27. Meeting FDA Guidance recommendations for replication-competent virus and insertional oncogenesis testing
    Kenneth G. Cornetta, Tsai‐Yu Lin, Danilo Pellin, Donald B. Kohn · 2022 · Molecular Therapy — Methods & Clinical Development
28. CReVIS-Seq: A highly accurate and multiplexable method for genome-wide mapping of lentiviral integration sites
    Heon Seok Kim, Gue‐Ho Hwang, Hyomin K. Lee, Taegeun Bae, Seong-Ho Park, Yong Jun Kim, Sun Lee, Jae-Hoon Park, Sangsu Bae, Junho K. Hur · 2021 · Molecular Therapy — Methods & Clinical Development
29. The Contained Self-Reactive Peripheral T Cell Repertoire: Size, Diversity, and Cellular Composition
    David M. Richards, Eliana Ruggiero, Ann-Cathrin Hofer, Julian P. Sefrin, Manfred Schmidt, Christof V. Kalle, Markus Feuerer · 2015 · The Journal of Immunology
30. Sola dosis facit venenum. Leukemia in gene therapy trials: a question of vectors, inserts and dosage?
    F. Staal, K. Pike-Overzet, Y. Ng, J. V. van Dongen · 2008 · Leukemia
31. Transposable Elements as Tools for Reshaping the Genome: It Is a Huge World After All!
    Solenne Bire, Florence Rouleux‐Bonnin · 2012 · Methods in molecular biology
32. High and long‐term von Willebrand factor expression after Sleeping Beauty transposon‐mediated gene therapy in a mouse model of severe von Willebrand disease
    Irina Portier, Karen Vanhoorelbeke, Sebastien Verhenne, Inge Pareyn, Nele Vandeputte, Hans Deckmyn, Daniel Goldenberg, H.B. Samal, Manvendra Singh, Zoltán Ivics et al. · 2017 · Journal of Thrombosis and Haemostasis
33. Genome-wide integration site detection using Cas9 enriched amplification-free long-range sequencing
    Joost van Haasteren, Altar M. Munis, Deborah R. Gill, Stephen C. Hyde · 2020 · Nucleic Acids Research
34. The genomic risk of somatic gene therapy
    Olga S. Kustikova, Martijn H. Brugman, Christopher Baum · 2010 · Seminars in Cancer Biology
35. DNA damage enhances integration of HIV-1 into macrophages by overcoming integrase inhibition
    Takayoshi Koyama, Binlian Sun, Kenzo Tokunaga, Masashi Tatsumi, Yukihito Ishizaka · 2013 · Retrovirology
36. Integration of retroviral vectors
    Richard Gabriel, Manfred Schmidt, Christof V. Kalle · 2012 · Current Opinion in Immunology
37. Gene therapy for Wiskott-Aldrich Syndrome—Long-term reconstitution and clinical benefits, but increased risk for leukemogenesis
    C. Braun, Maximilian Witzel, A. Paruzynski, K. Boztug, C. von Kalle, M. Schmidt, C. Klein · 2014 · Rare Diseases
38. Clonal tracking of hESCs reveals differential contribution to functional assays
    Morag H. Stewart, Sean C. Bendall, Marilyne Levadoux‐Martin, Mickie Bhatia · 2010 · Nature Methods
39. Transient expression of genes delivered to newborn rat liver using recombinant adeno‐associated virus 2/8 vectors
    Maude Flageul, Dominique Aubert, Virginie Pichard, Tuan Huy Nguyen, Ali Nowrouzi, Manfred Schmidt, Nicolas Ferry · 2009 · The Journal of Gene Medicine
40. VISPA: a Computational pipeline for the identification and analysis of genomic vector integration sites
    Andrea Calabria, Simone Leo, Fabrizio Benedicenti, Daniela Cesana, Giulio Spinozzi, Massimilano Orsini, Stefania Merella, Elia Stupka, Gianluigi Zanetti, Eugenio Montini · 2014 · Genome Medicine
41. Vector Integration and Tumorigenesis
    C. von Kalle, A. Deichmann, M. Schmidt · 2014 · Human Gene Therapy
42. Human somatic cell mutagenesis creates genetically tractable sarcomas
    Sam D. Molyneux, Paul D. Waterhouse, Dawne N. Shelton, Yang Washington Shao, Christopher M Watling, Qinglian Tang, Isaac S. Harris, Brendan Craig Dickson, Pirashaanthy Tharmapalan, Geir Kjetil Sandve et al. · 2014 · Nature Genetics
43. Linear and exponential TAIL-PCR: a method for efficient and quick amplification of flanking sequences adjacent to Tn5 transposon insertion sites
    Xianbo Jia, Xinjian Lin, Jichen Chen · 2017 · AMB Express
44. Comparative clonal analysis of reconstitution kinetics after transplantation of hematopoietic stem cells gene marked with a lentiviral SIN or a γ-retroviral LTR vector.
    K. Cornils, C. Bartholomae, L. Thielecke, C. Lange, A. Arens, I. Glauche, Ulrike Mock, K. Riecken, Sebastian Gerdes, C. von Kalle et al. · 2013 · Experimental Hematology
45. Analyzing the Number of Common Integration Sites of Viral Vectors – New Methods and Computer Programs
    U. Abel, A. Deichmann, A. Nowrouzi, R. Gabriel, C. Bartholomae, H. Glimm, C. von Kalle, M. Schmidt · 2011 · PLoS ONE
46. Genome wide functional genetics in haploid cells
    Ulrich Elling, Josef Martin Penninger · 2014 · FEBS Letters
47. Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia
    Shubhranshu Debnath, Pekka Jaako, Kavitha Siva, Michael Rothe, Jun Chen, Maria Dahl, Hubert Bobby Gaspar, Johan Flygare, Axel Schambach, Stefan Karlsson · 2017 · Molecular Therapy
48. Self-inactivating MLV vectors have a reduced genotoxic profile in human epidermal keratinocytes
    A. Cavazza, F. Cocchiarella, C. Bartholomae, M. Schmidt, C. Pincelli, F. Larcher, F. Mavilio · 2013 · Gene Therapy
49. Preclinical Efficacy and Safety Evaluation of Hematopoietic Stem Cell Gene Therapy in a Mouse Model of MNGIE
    Rana Yadak, Raquel Cabrera-Pérez, Javier Torres‐Torronteras, Marianna Bugiani, Joost C. Haeck, Marshall W. Huston, Elly Bogaerts, Steffi Goffart, Edwin H. Jacobs, Merel Stok et al. · 2018 · Molecular Therapy — Methods & Clinical Development
50. No tumour-initiating risk associated with scAAV transduction in newborn rat liver
    Vanessa Gauttier, Virginie Pichard, Denise Aubert, Christine Kaeppel, Manfred Schmidt, N. Ferry, Sophie Conchon · 2013 · Gene Therapy
51. A Non-Dicer RNase III and Four Other Novel Factors Required for RNAi-Mediated Transposon Suppression in the Human Pathogenic Yeast Cryptococcus neoformans
    Jordan E. Burke, Adam D Longhurst, Prashanthi Natarajan, Beiduo Rao, S. John Liu, Jade Sales-Lee, Yasaman Mortensen, James J. Moresco, Jolene K. Diedrich, John R. Yates et al. · 2019 · G3 Genes Genomes Genetics
52. EVI1 Inhibits Apoptosis Induced by Antileukemic Drugs via Upregulation of CDKN1A/p21/WAF in Human Myeloid Cells
    Anna Rommer, Birgit Steinmetz, Friederike Herbst, Hubert Hackl, Petra Heffeter, Daniela Heilos, Martin Filipits, Katarina Steinleitner, Shayda Hemmati, Irene Herbacek et al. · 2013 · PLoS ONE
53. Engineered dendritic cells from cord blood and adult blood accelerate effector T cell immune reconstitution against HCMV
    Anusara Daenthanasanmak, Gustavo Salguero, Bala Sai Sundarasetty, Claudia Waskow, Kadriye Nehir Cosgun, Carlos A. Guzmán, Peggy Riese, Laura Gerasch, Andreas Schneider, Alexandra Ingendoh‐Tsakmakidis et al. · 2015 · Molecular Therapy — Methods & Clinical Development
54. Evaluating a Ligation-Mediated PCR and Pyrosequencing Method for the Detection of Clonal Contribution in Polyclonal Retrovirally Transduced Samples
    M. Brugman, J. D. Suerth, M. Rothe, S. Suerbaum, A. Schambach, U. Modlich, O. Kustikova, C. Baum · 2013 · Human Gene Therapy Methods
55. High Efficiency Restriction Enzyme–Free Linear Amplification-Mediated Polymerase Chain Reaction Approach for Tracking Lentiviral Integration Sites Does Not Abrogate Retrieval Bias
    Chuanfeng Wu, Alexander Jares, Thomas Winkler, Jianjun Xie, Jean‐Yves Métais, Cynthia E. Dunbar · 2012 · Human Gene Therapy
56. Mapping the Chromosomal Insertion Site of the GFP Transgene of UBC-GFP Mice to the MHC Locus
    Shanrun Liu, Jonathan R. Lockhart, Suean Daimia Fontenard, Mike Berlett, Thomas M. Ryan · 2020 · The Journal of Immunology
57. Replication-incompetent gammaretroviral and lentiviral vector-based insertional mutagenesis screens identify prostate cancer progression genes
    Victor M. Bii, Casey P. Collins, Jonah D. Hocum, Grant D. Trobridge · 2018 · Oncotarget
58. A track of the clones: new developments in cellular barcoding
    Anne-Marie Lyne, David G. Kent, Elisa Laurenti, Kerstin Cornils, Ingmar Glauche, Leïla Perié · 2018 · Experimental Hematology
59. Infection with a newly designed dual fluorescent reporter HIV-1 effectively identifies latently infected CD4+ T cells
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60. Insights gained from single-cell analysis of chimeric antigen receptor T-cell immunotherapy in cancer
    Lu Tang, Zhongpei Huang, Heng Mei, Yu Hu · 2023 · Military Medical Research
61. From Bench to Bedside: Preclinical Evaluation of a Self-Inactivating Gammaretroviral Vector for the Gene Therapy of X-linked Chronic Granulomatous Disease
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62. Metabolic Correction of Congenital Erythropoietic Porphyria with iPSCs Free of Reprogramming Factors
    Aurélie Bedel, Miguel Taillepierre, Veronique Guyonnet‐Dupérat, Éric Lippert, Pierre R. Dubus, Sandrine Dabernat, Thibaud Mautuit, Bruno Cardinaud, C. Pain, Benoı̂t Rousseau et al. · 2012 · The American Journal of Human Genetics
63. Transgenic Expression of Human Glial Cell Line-Derived Neurotrophic Factor from Integration-Deficient Lentiviral Vectors is Neuroprotective in a Rodent Model of Parkinson's Disease
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64. DNA sonication inverse PCR for genome scale analysis of uncharacterized flanking sequences
    David E. Alquezar‐Planas, Ulrike Löber, Pin Cui, Claudia Quedenau, Wei Chen, Alex David Greenwood · 2020 · Methods in Ecology and Evolution
65. Hematopoietic Tumors in a Mouse Model of X-linked Chronic Granulomatous Disease after Lentiviral Vector-Mediated Gene Therapy
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66. Comprehensive profiling of retroviral integration sites using target enrichment methods from historical koala samples without an assembled reference genome
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67. Comparing molecular and computational approaches for detecting viral integration of AAV gene therapy constructs
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68. A genome-wide analysis of lentivector integration sites using targeted sequence capture and next generation sequencing technology.
    D. Ustek, S. Sırma, Ergun Gumus, M. Arıkan, A. Çakiris, N. Abacı, J. Mathew, Z. Emrence, H. Azakli, F. Coşan et al. · 2012 · Infection, Genetics and Evolution
69. Detection of Retroviral Integration Sites by Linear Amplification-Mediated PCR and Tracking of Individual Integration Clones in Different Samples
    Manfred Schmidt, Kerstin Schwarzwaelder, Cynthia C. Bartholomae, Hanno Glimm, Christof V. Kalle · 2009 · Methods in molecular biology
70. INSERT-seq enables high-resolution mapping of genomically integrated DNA using Nanopore sequencing
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71. Using Barcoded HIV Ensembles (B‐HIVE) for Single Provirus Transcriptomics
    Heng‐Chang Chen, Eduard Valera Zorita, Guillaume J. P. Filion · 2018 · Current Protocols in Molecular Biology
72. Long-Term Vector Integration Site Analysis Following Retroviral Mediated Gene Transfer to Hematopoietic Stem Cells for the Treatment of HIV Infection
    J. Hayakawa, Kareem N. Washington, N. Uchida, Oswald A. Phang, E. Kang, Matthew M. Hsieh, J. Tisdale · 2008 · PLoS ONE
73. Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML
    Ju Huang, Yuanfeng Liu, B C Y Au, Dwayne L. Barber, Andrea Arruda, Axel Schambach, Michael Rothe, Mark David Minden, Christopher J. Paige, Jeffrey A. Medin · 2016 · Molecular Therapy — Methods & Clinical Development
74. Integration Site and Clonal Expansion in Human Chronic Retroviral Infection and Gene Therapy
    Heather A. Niederer, Charles R. M. Bangham · 2014 · Viruses
75. Sleeping Beauty‐mediated correction of Fanconi anemia type C
    Kendra A. Hyland, Erik R. Olson, Karl J. Clark, Elena L. Aronovich, Perry B. Hackett, Bruce R. Blazar, Jakub Tolar, R. Scott McIvor · 2011 · The Journal of Gene Medicine
76. High-Throughput, Sensitive Quantification of Repopulating Hematopoietic Stem Cell Clones
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77. Lentiviral Vector-based Insertional Mutagenesis Identifies Genes Involved in the Resistance to Targeted Anticancer Therapies
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78. Generation of lentivirus-induced dendritic cells under GMP-compliant conditions for adaptive immune reconstitution against cytomegalovirus after stem cell transplantation
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79. Integration and the risk of liver cancer—Is there a real risk?
    Aradhana Kasimsetty, Denise E. Sabatino · 2024 · Journal of Viral Hepatitis
80. Insertion Site Pattern: Global Approach by Linear Amplification-Mediated PCR and Mass Sequencing
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81. Multi-reporter selection for the design of active and more specific zinc-finger nucleases for genome editing
    Benjamin L. Oakes, Danny F. Xia, Elizabeth F. Rowland, Denise J. Xu, Irina Ankoudinova, Jennifer S. Borchardt, Lei Zhang, Patrick Wen Feng Li, Jeffrey C. Miller, Edward J. Rebar et al. · 2016 · Nature Communications
82. High-titer foamy virus vector transduction and integration sites of human CD34+ cell–derived SCID-repopulating cells
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83. Gene Therapy - Developments and Future Perspectives
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84. ISAnalytics enables longitudinal and high-throughput clonal tracking studies in hematopoietic stem cell gene therapy applications
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85. Recent advances in single-nucleotide variant assay: From in vitro detection to in vivo imaging
    Huimin Yuan, Wenjing Liu, Juan Hu, Chun‐yang Zhang · 2024 · TrAC Trends in Analytical Chemistry
86. The LAM-PCR Method to Sequence LV Integration Sites
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87. VSeq-Toolkit: Comprehensive Computational Analysis of Viral Vectors in Gene Therapy
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88. Diagnosis and Early Prediction of Lymphoma Using High-Throughput Clonality Analysis of Bovine Leukemia Virus-Infected Cells
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89. Quantitative Shearing Linear Amplification Polymerase Chain Reaction: An Improved Method for Quantifying Lentiviral Vector Insertion Sites in Transplanted Hematopoietic Cell Systems
    Sheng Zhou, Melissa A. Bonner, Yong‐Dong Wang, Samuel Rapp, Suk See De Ravin, Harry L. Malech, Brian P. Sorrentino · 2014 · Human Gene Therapy Methods
90. Deciphering integration loci of CHO manufacturing cell lines using long read nanopore sequencing.
    Christian Clappier, Dennis Böttner, Daniel Heinzelmann, Anna Stadermann, P. Schulz, M. Schmidt, Benjamin Lindner · 2023 · New Biotechnology
91. Integration Site Analysis in Gene Therapy Patients: Expectations and Reality
    Luca Biasco · 2017 · Human Gene Therapy
92. Mapping Active Gene-Regulatory Regions in Human Repopulating Long-Term HSCs
    Peer Wünsche, Elias Eckert, Tim Holland‐Letz, Anna Paruzynski, Agnes Hotz‐Wagenblatt, Raffaele Fronza, Tim Rath, Irene Gil-Fariña, Manfred Schmidt, Christof V. Kalle et al. · 2018 · Cell stem cell
93. adLIMS: a customized open source software that allows bridging clinical and basic molecular research studies
    Andrea Calabria, Giulio Spinozzi, Fabrizio Benedicenti, Erika Tenderini, Eugenio Montini · 2015 · BMC Bioinformatics
94. Shedding of clinical-grade lentiviral vectors is not detected in a gene therapy setting
    Martina Cesani, Tiziana Plati, Laura Lorioli, Fabrizio Benedicenti, Daniela Redaelli, Francesca Dionisio, Luca Biasco, Eugenio Montini, Luigi Naldini, Alessandra Biffi · 2015 · Gene Therapy
95. Linear Amplification Mediated PCR – Localization of Genetic Elements and Characterization of Unknown Flanking DNA
    Richard Gabriel, Ina Kutschera, Cynthia C. Bartholomae, Christof V. Kalle, Manfred Schmidt · 2014 · Journal of Visualized Experiments
96. Rapid, accurate mapping of transgene integration in viable rhesus macaque embryos using enhanced-specificity tagmentation-assisted PCR
    Junghyun Ryu, William Chan, Jochen Martin Wettengel, Carol B. Hanna, Benjamin J. Burwitz, Jon D. Hennebold, Benjamin N. Bimber · 2022 · Molecular Therapy — Methods & Clinical Development
97. Non-clinical safety assessment of novel drug modalities: Genome safety perspectives on viral-, nuclease- and nucleotide-based gene therapies
    Myriam Lemmens, Lena Dorsheimer, Andreas Zeller, Yasmin Dietz · 2024 · Mutation Research/Genetic Toxicology and Environmental Mutagenesis
98. High-throughput monitoring of integration site clonality in preclinical and clinical gene therapy studies
    F. Giordano, J. Appelt, Barbara Link, Sebastian Gerdes, Christin-Isabell Lehrer, Simone J. Scholz, A. Paruzynski, I. Roeder, F. Wenz, H. Glimm et al. · 2015 · Molecular Therapy: Methods & Clinical Development
99. piggyBac Transposon-Based Insertional Mutagenesis in Mouse Haploid Embryonic Stem Cells
    Stephen J. Pettitt, E‐Pien Tan, Kosuke Yusa · 2014 · Methods in molecular biology
100. TEG001 Insert Integrity from Vector Producer Cells until Medicinal Product
     Straetemans, Trudy, Janssen, Anke, Jansen, Koen, Doorn, Ruud, Aarts, Tineke, van Muyden, Anna D.D., Simonis, Marieke, Bergboer, Judith, de Witte, Moniek, Sebestyen, Zsolt et al. · 2020 · Molecular Therapy