High-resolution insertion-site analysis by linear amplification-mediated PCR (LAM-PCR)

Schmidt, Manfred, Schwarzwaelder, Kerstin, Bartholomae, Cynthia, Zaoui, Karim, Ball, Claudia, Pilz, Ingo, Braun, Sandra, Glimm, Hanno +1 more·2007·Nature Methods

DOI 10.1038/nmeth1103

Cited by (328)

Items 201–300 of 328

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Joerg Enssle, Grant D. Trobridge, Kirsten A. Keyser, Christina M. Ironside, Brian C. Beard, Hans‐Peter Kiem · 2009 · Human Gene Therapy
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Karl Petri, Richard Gabriel, Leticia Agúndez, Raffaele Fronza, Saira Afzal, Christine Kaeppel, R. Michael Linden, Els Henckaerts, Manfred Schmidt · 2015 · Journal of Virology
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Eleni Papanikolaou, Anna Paruzynski, Ioannis N. Kasampalidis, Annette Deichmann, Evangelos Stamateris, Manfred Schmidt, Christof V. Kalle, Nicholas P. Anagnou · 2014 · Molecular Therapy
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Giada Mattiuzzo, Yasuhiro Takeuchi, Linda Scobie · 2012 · Methods in molecular biology
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Zhao Zhang, Hua Jiang, Li Huang, Sixi Liu, Xiaoya Zhou, Yun Cai, Ming Li, Fei Gao, Xiaoting Liang, Kam‐Sze Tsang et al. · 2024 · Protein & Cell
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Hanno Glimm, Claudia R. Ball, Christof V. Kalle · 2011 · Cell stem cell
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Coral González-Prieto, Richard Gabriel, Christoph Dehio, Manfred Schmidt, Matxalen Llosa · 2017 · Applied and Environmental Microbiology
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Ping Zhang, Devika Ganesamoorthy, Son Hoang Nguyen, Raymond Au, Lachlan Coin, Siok‐Keen Tey · 2020 · Journal for ImmunoTherapy of Cancer
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Georg von Jonquières, Caroline D. Rae, Gary D. Housley · 2021 · Frontiers in Cellular Neuroscience
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Dan Bai, Xi Zhou, Wang Luo, Hongyan Yu, Shulian Bai, You Wu, Lin Song, Kena Chen, Yaxing Xie, Xueping Chen et al. · 2022 · Biosensors and Bioelectronics
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Oksana Zavidij, Claudia R. Ball, Friederike Herbst, Felix Oppel, Sylvia Fessler, Manfred Schmidt, Christof V. Kalle, Hanno Glimm · 2012 · Stem Cells
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Christoph Stephan, Hanna‐Mari Baldauf, Joanne Barry, Frank Anton Giordano, Cynthia C. Bartholomae, Annette Haberl, Markus Bickel, Manfred Schmidt, Stephanie Laufs, Lars Kaderali et al. · 2014 · Journal of Antimicrobial Chemotherapy
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Simone Scholz, Raffaele Fronza, Cynthia C. Bartholomae, Daniela Cesana, Eugenio Montini, Christof V. Kalle, Irene Gil-Fariña, Manfred Schmidt · 2017 · Human Gene Therapy
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Giulio Di Minin, Andreas Postlmayr, Anton Wutz · 2018 · PLoS Computational Biology
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Daniela Cesana, Monica Volpin, Yasmin Natalia Serina Secanechia, Eugenio Montini · 2017 · Springer eBooks
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Ruhi Phaltane, Reinhard Haemmerle, Michael Rothe, Ute Modlich, Thomas Moritz · 2013 · Human Gene Therapy
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Shengwen Zhang, Amy Bastille, Susana Gordo, Nikhil Ramesh, Jenisha Vora, Elizabeth McCarthy, Xiaohan Zhang, Dylan Frank, Chih‐Wei Ko, Carmen Wu et al. · 2022 · PLoS ONE
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Marshall W. Huston, Adriaan R.A. Riegman, Rana Yadak, Yvette van Helsdingen, Helen de Boer, Niek Peter van Til, Gerard Wagemaker · 2014 · Human Gene Therapy
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Aaron Shaw, Guiandre L. Joseph, Aparna C. Jasti, Lakshmi Sastry, Scott R. Witting, Kenneth G. Cornetta · 2016 · Gene Therapy
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Tim Aranyossy, Lars Thielecke, Ingmar Glauche, Boris Fehse, Kerstin Cornils · 2017 · Human Gene Therapy
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Wenjie Ouyang, Guoyi Dong, Weihua Zhao, Jing Li, Ziheng Zhou, Gaohui Yang, Rongrong Liu, Yue Li, Qiaoxia Zhang, Xin Du et al. · 2020 · Human Gene Therapy
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Jun Wang, Nan Xiao, Zhengnong Zhu, Haiyan Qiao, Fang Zhao, Lukun Zhang, Jizhou Gou, Mengji Lu, Yun He, Hongzhou Lu et al. · 2025 · Signal Transduction and Targeted Therapy
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Catherine W. Kaiser, Eric Christian Rouchka, Melissa L. Smith · 2026 · Journal of Translational Medicine
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Sofie A. O’Brien, Juhi Ojha, Paul Y K Wu, Wei‐Shou Hu · 2020 · Biotechnology Progress
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Pin Cui · 2016 · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver
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