Lateral habenula neurons signal errors in the prediction of reward information

Bromberg-Martin, Ethan S, Hikosaka, Okihide·2011·Nature Neuroscience
DOI 10.1038/nn.2902

Cited by (275)

Items 201–275 of 275

  1. Basal Ganglia—A Motion Perspective
    Sten E. Grillner, Brita Robertson, Jeanette Hellgren Kotaleski · 2020 · Comprehensive physiology
  2. Habenula contributions to negative self-cognitions
    Po‐Han Kung, Matthew D. Greaves, Eva Guerrero-Hreins, Ben J. Harrison, Christopher G. Davey, Kim Louise Felmingham, Holly Carey, Priya Sumithran, Robyn M. Brown, Bradford Armstrong Moffat et al. · 2025 · Nature Communications
  3. A decision-space model explains context-specific decision-making
    Dirk W. Beck, Cory N. Heaton, Luis D. Davila, Lara I. Rakocevic, Sabrina M. Drammis, Danil Tyulmankov, Atanu Giri, Shreeya Umashankar Beck, Qingyang Zhang, Michael Pokojovy et al. · 2025 · Nature Communications
  4. Mediation of mPFC‐LHb pathway in acupuncture inhibition of cocaine psychomotor activity
    Suchan Chang, Hyung Kyu Kim, Yeonhee Ryu, Han Byeol Jang, Danbi Ahn, Bong Hyo Lee, Dong‐ho Youn, Bae Hwan Lee, Hee Young Kim · 2023 · Addiction Biology
  5. Metacognition of curiosity: People underestimate the seductive lure of non-instrumental information
    Sunae Kim, Michiko Sakaki, Kou Murayama · 2023 · Psychonomic Bulletin & Review
  6. Nicotinic Acetylcholine Receptors Along the Habenulo-Interpeduncular Pathway: Roles in Nicotine Withdrawal and Other Aversive Aspects
    Dang Q. Dao, Ramiro Salas, Mariella De Biasi · 2014 · The Receptors
  7. Intrinsic functional connections determine how curiosity and prediction errors enhance memory
    Kathrin C. J. Eschmann, Ashvanti Valji, Kim S. Graham, Andrew D. Lawrence, Matthias J. Gruber · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  8. Is interesting knowledge a reward? An integrative model of emotion, reward and appraisal frameworks of epistemic curiosity.
    Asli Erdemli, Catherine Audrin, David Sander · 2024
  9. Pharmacological evaluation of lateral habenula and rostromedial tegmental nucleus in the expression of ethanol-induced place preference
    Sukanya G. Gakare, Rajesh Ramesh Ugale · 2023 · Behavioural Pharmacology
  10. Do goldfish like to be informed?
    Victor Ajuwon, Tiago Monteiro, Mark E. Walton, Alex Kacelnik · 2025 · Proceedings of the Royal Society B Biological Sciences
  11. Does dopamine synthesis capacity predict individual variation in curiosity?
    Lieke L. F. van Lieshout, Ruben van den Bosch, Lieke Hofmans, Floris P. de Lange, Roshan Cools · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  12. Nonlinear computation by a habenula-driven recurrent inhibitory network in the raphe
    Michael B. Lynn, Sean D. Geddes, Mohamad A. Chahrour, Sébastien Maillé, Léa Caya-Bissonnette, Emerson F. Harkin, Erik Harvey‐Girard, Samir Haj‐Dahmane, Richard Naud, Jean-Claude Béïque · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  13. When cognition overshadows affect, maladaptive information-seeking arises
    Irene Cogliati Dezza, Gaia Molinaro, Tom Verguts · 2024
  14. Addressing altered anticipation as a transdiagnostic target through computational psychiatry
    Sepúlveda, Pradyumna, Aitsahalia, Ines, Kumar, Krishan, Atkin, Tobias, Iigaya, Kiyohito · 2025 · Biological Psychiatry Cognitive Neuroscience and Neuroimaging
  15. A pathway from the anterior cingulate cortex to the lateral habenula controls chronic pain-induced depression in male mice
    Sarah H. Journée, Victor Mathis, Robin Waegaert, Sebahat Ozkan, Enora Langlois, Pilar Ortiz-Teba, Beyza Ayazgök, Léa J. Becker, Mithil Gaikwad, Michel Barrot et al. · 2026 · Neuropsychopharmacology
  16. Curiosity
    Coltan Scrivner · 2024 · Oxford University Press eBooks
  17. Habenula-Induced Inhibition of Midbrain Dopamine Neurons Is Diminished by Lesions of the Rostromedial Tegmental Nucleus
    P. Leon Brown, Heather Palacorolla, Dana L. Brady, Katelyn E. Riegger, Gregory I. Elmer, Paul D. Shepard · 2017 · Journal of Neuroscience
  18. Tonic activity in lateral habenula neurons promotes disengagement from reward-seeking behavior
    Brianna J. Sleezer, Ryan J. Post, David A. Bulkin, R. Becket Ebitz, Vladlena Lee, Kasey J. Han, Melissa R. Warden · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  19. Curiosity: A behavioral biology perspective
    Coltan Scrivner · 2021
  20. Efectos de la estimulación eléctrica habenular en la modulación de respuestas emocionales en ratas Wistar
    María Laura Herrera, Natalia Guisselle Rubio, Juan Pablo Quintanilla, Víctor Manuel Huerta, Alejandro Osorio-Forero, Melissa Andrea Cárdenas Molano, Karen Corredor, Mario Andres Valderrama, Fernando P. Cárdenas · 2018 · Acta Colombiana de Psicología
  21. On the value of advanced information about delayed rewards
    Alejandro Macías, Armando D. Machado, Marco Vasconcelos · 2024 · Animal Cognition
  22. The Lateral Habenula to Ventral Tegmental Area Pathway Is Required for Aversive Learning and Defensive Behaviors
    Marina R. Ihidoype, Jose Cesar Hernandez Silva, Kelly-Ann Pellerin, Ekaterina Martian, Maryse Pinel, Christophe D. Proulx · 2026 · Journal of Neuroscience
  23. Inhibition of ventral tegmental area projections to the paraventricular thalamus attenuates conditioned cues-induced heroin seeking behavior in rats
    Yiying Zhou, Wenchang Li, Dandan Cai, Dingding Zhuang, Xin Zhang, Miaojun Lai, Weisheng Chen, Wenhua Zhou, Huaqiang Zhu · 2025 · Metabolic Brain Disease
  24. Mu Opioid Receptor mRNA and Protein Localization Across the Rat and Mouse Habenula
    Alpa Popat, Rhiana C. Simon, Beatriz B. Aoyama, Ahana Wokhlu, Aliza T. Ehrlich, Corey C. Harwell, Elyssa B. Margolis · 2026 · The Journal of Comparative Neurology
  25. The macaque medial prefrontal cortex simultaneously represents self and others’ reward prediction error
    Atsushi Noritake, Masaki Isoda · 2025 · Cell Reports
  26. Efficiency and prioritization of inference-based credit assignment
    Rani Moran, Peter Dayan, Raymond J. Dolan · 2021 · Current Biology
  27. Investigating the Contributions of Hippocampal Memory and Reward Valuation Systems to Cost-Benefit Decision Making
    Valerie L. Tryon · 2017 · ResearchWorks at the University of Washington (University of Washington)
  28. The entopeduncular nucleus drives lateral habenula responses to negative but not positive or neutral affective stimuli
    Hao Li, Dominika Pullmann, Thomas C. Jhou · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  29. Reply to de Fleurian et al.: Toward a fuller understanding of reward prediction errors and their role in musical pleasure
    Benjamin P. Gold, Ernest Mas Herrero, Alain Dagher, Robert J. Zatorre · 2019 · Proceedings of the National Academy of Sciences
  30. Dataset: Prediction Errors Disrupt Hippocampal Representations and Update Episodic Memories
    Alyssa Hannah Sinclair, Grace M. Manalili, Iva K. Brunec, R. Alison Adcock, Morgan Barense · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  31. People adaptively use information to improve their internal and external states
    Irene Cogliati Dezza, Christina Maher, Tali Sharot · 2021
  32. The Role of Lactate in Drug Addiction
    Ruiqi Chen, Rui‐Hua Xu, Junpeng Ma · 2025 · The FASEB Journal
  33. Ventral pallidum GABA neuron inhibition augments context-appropriate defensive responses to learned threat cues
    Erica M. Ramirez, Maricela X. Martinez, Ryan K. Rokerya, Vanessa Alizo Vera, Christina M. Ruiz, Mitchell R. Farrell, Shreeya A. Walawalkar, Hazael Ramirez-Ramirez, Grace J Kollman, Stephen V. Mahler · 2026 · Neurobiology of Stress
  34. The reins of the midbrain: Task-based habenula function in healthy humans
    Amat Surroca-López, F. Medina-Osuna, Trevor Steward, Carles Soriano‐Mas · 2026 · Neuroscience & Biobehavioral Reviews
  35. Uncertainty reduction as a candidate primary reinforcer: an evolutionary and neural account
    Alan Lincoln · 2026 · Academia Neuroscience and Brain Research
  36. Affect is the Evaluative Context for the Brain’s Shifting Goals
    Adam D. LaMotte · 2025 · Adaptive Behavior
  37. Hippocampal-midbrain circuit enhances the pleasure of anticipation in the prefrontal cortex
    Kiyohito Iigaya, Tobias U. Hauser, Zeb L. Kurth-Nelson, John P. O’Doherty, Peter Dayan, Raymond J. Dolan · 2019 · CaltechAUTHORS (California Institute of Technology)
  38. The brain at play: neural substrates of social play behaviour in adolescent rats
    Linda W. M. van Kerkhof · 2013 · Utrecht University Repository (Utrecht University)
  39. Neuroscience of Value‐Guided Choice
    Gerhard Jocham, Erie D. Boorman, Timothy E.J. Behrens · 2016 · Wiley eBooks
  40. Curiosity for information predicts well-being during COVID-19 Pandemic: Contributions of loneliness and daily lifestyle
    Annabel B. Losecaat Vermeer, Anne-Katrin Muth, Damiano Terenzi, Soyoung Q. Park · 2021
  41. Erratum: Lateral habenula neurons signal errors in the prediction of reward information
    Ethan S. Bromberg-Martin, Okihide Hikosaka · 2011 · Nature Neuroscience
  42. The Effect of Prediction Error on Episodic Memory Encoding is Modulated by the Outcome of the Predictions
    Francesco Pupillo, Javier Ortiz-Tudela, Rasmus Bruckner, Yee Lee Shing · 2022
  43. Computational Primitives for Cost-Benefit Decision-Making
    Lara I. Rakocevic, Luis D. Davila, Cory N. Heaton, Dirk W. Beck, Raquel J. Ibáñez Alcalá, Sazzat Hossain, Neftali F. Reyes, Andrea Y. Macias, Alexis A. Salcido, Danil Tyulmankov et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  44. Circuitaria e assinatura neuroquímica das projeções entre a habenula lateral, o núcleo tegmental rostromedial e o núcleo dorsal da rafe.
    Chemutai Sego · 2013
  45. Monoaminergic Regulation of MeCP2 Phosphorylation in Mouse Models of Psychiatric Disease
    Ashley N. Hutchinson · 2011
  46. Förhållandet mellan nyfikenhet och en förväntad ökning av information : Nyfikenhet påverkas av möjligheten till information som förväntas reducera osäkerhet
    Emil Grönlund · 2016 · KTH Publication Database DiVA (KTH Royal Institute of Technology)
  47. The manifold role of reward value on visual attention
    Zachary J. J. Roper, Jatin G. Vaidya, Shaun P. Vecera, Edward A. Wasserman, Eliot Hazeltine, Michelle Voss · 2015
  48. On the Role of Intrinsic Rewards in Communication
    Johan Lauwereyns, Shizuka Sakurai Lauwereyns · 2016 · Advances in cognitive neurodynamics
  49. The Role of the Habenulomesencephalic Circuit in Cocaine Addiction
    Wanhong Zuo, Krešimir Krnjević, Alex Bekker, J.-H. Ye · 2017 · Elsevier eBooks
  50. Altered Neural and Behavioral Associability-Based Learning in Posttraumatic Stress Disorder
    Vanessa M. Brown · 2015 · VTechWorks (Virginia Tech)
  51. Neural Circuit Mechanisms Underlying Dopamine Reward Prediction Errors
    Ju Tian · 2016 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
  52. Functional Anatomy of the Major Tracts
    Nivedita Agarwal · 2017 · Springer eBooks
  53. Editorial
    Bidyut Baran Saha, Kyaw Thu, Agung Tri Wijayanta · 2018 · Evergreen
  54. Autistic traits influence the strategic diversity of information sampling: insights from two-stage decision models
    Haoyang Lu, Li Yi, Hang Zhang · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  55. Effects of Predictive Information on Pupil Dilation during the Evaluation of Food Images
    Kajornvut Ounjai, Shunsuke Kobayashi, Johan Lauwereyns · 2019 · Biomedical Engineering International Conference
  56. Spatial and temporal gaze decisions during walking: role of uncertainty, task priority, and motor cost
    Domínguez Zamora, Francisco Javier · 2020
  57. Neural Circuitry of Information Seeking
    Ethan S. Bromberg-Martin, Ilya E. Monosov · 2020
  58. Lateral Habenula Neurons Signal Step-by-Step Changes of Reward Forecast
    Hyunchan Lee, Okihide Hikosaka · 2022 · SSRN Electronic Journal
  59. Faculty Opinions recommendation of A hypothalamus-habenula circuit controls aversion.
    Sreedharan Sajikumar, Radha Raghuraman · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  60. Endocannabinoid signaling in the lateral habenula regulates opioid addiction
    Jiang-Hong Ye, Kelsey L. Tam, Xinyu Gu, Wanhong Zuo, Rao Fu, Ying‐Xian Pan · 2023 · Elsevier eBooks
  61. Sensorimotor-linked reward modulates smooth pursuit eye movements in monkeys
    Yongxiang Hu, Huan Wang, Mati Joshua, Yan Yang · 2024 · Frontiers in Neuroscience
  62. The lateral habenula is required for maternal behavior in the mouse dam
    Jessie Benedict, Robert H. Cudmore, Diarra Oden, Aleah Spruell, David J. Linden · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  63. The effect of noninstrumental information on reward learning
    Jake Ryan Embrey, Amy X. Li, Shi Xian Liew, Ben Rhodri Newell · 2024 · Memory & Cognition
  64. Computational Primitives for Cost-Benefit Decision-Making
    Alexander Friedman, Lara I. Rakocevic, Luis D. Davila, Cory N. Heaton, Dirk W. Beck, Raquel J. Ibáñez Alcalá, Sazzat Hossain, Neftali F. Reyes, Andrea Y. Macias, Alexis A. Salcido et al. · 2025 · SSRN Electronic Journal
  65. Asymmetrical modulation of fear expression via GABA B receptors in the mouse medial habenula
    Cihan Önal, Peter Koppensteiner, Mary Muhia, Elodie Le Monnier, Ryuichi Shigemoto · 2026 · Proceedings of the National Academy of Sciences
  66. Exploring the Convergence of Curiosity Across Behavioural Tasks and Personality Trait Questionnaires
    Hayley K. Jach · 2025 · Social and Personality Psychology Compass
  67. The lateral habenula as a link between negative outcomes and adaptive strategy switching
    Victoria I. Hones, Maeve C. Bottoms, Jesse T. Miles, Sheri J. Y. Mizumori · 2026 · Learning & Memory
  68. Rôle des stimuli sensoriels et de la palatabilité dans la prise orale de nicotine chez la souris
    Salma Tannous · 2019 · theses.fr (ABES)
  69. The Role of Progress-Based Intrinsic Motivation in Learning : Evidence from Human Behavior and Future Directions
    Alexandr Ten · 2022
  70. Study of the role of the lateral habenula in fear conditioning and stress response in rat
    Laura Durieux · 2021 · theses.fr (ABES)
  71. Learning reinforces curiosity for related information
    Yaniv Abir, Jane Mok, Christopher A. Baldassano, Caroline B Marvin, Daphna Shohamy A · 2026 · Proceedings of the National Academy of Sciences
  72. Habenula volume alterations in adults born very preterm
    Theresa Stüwe, Angelika Maurer, Marcel Daamen, Barbara Daria Wichtmann, Hyun Soo Ko, Neeraj Upadhyay, Benita Schmitz‐Koep, Markus Essler, Julian Luetkens, Claus Zimmer et al. · 2026 · Scientific Reports
  73. Multiplexing of functionally distinct inputs by intrinsic modulation of spike timing in a monoaminergic nucleus
    Michael B. Lynn, Leonard Maler, Jean-Claude Béïque · 2026 · Cell Reports
  74. Evolutionary rise of a synaptic mechanism for creating and diversifying key reinforcement signals
    Natalia Rodríguez-Sosa, Lupita Rios, You‐Hsin Lin, Volodymyr Rybalchenko, Yash Sharma, Alaa Hajeissa, Ian Chambers, Nien-Shao Wang, Raghav Rajesh, Vishal Narla et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  75. Apathy is associated with lower perceptual curiosity
    Leon Tay, Patrick Cooper, Emily Colton, Jocelyn A. Halim, Stefan Bode, Trevor T.‐J. Chong · 2026 · Cognition