Pain vulnerability: a neurobiological perspective
Denk, Franziska, McMahon, Stephen B, Tracey, Irene·2014·Nature Neuroscience
DOI 10.1038/nn.3628
Cited by (361)
Items 101–200 of 361
- The OPRM1 A118G polymorphism modulates the descending pain modulatory system for individual pain experience in young women with primary dysmenorrheaShyh‐Yuh Wei, Li‐Fen Chen, Ming‐Wei Lin, Wei‐Chi Li, Intan Low, Ching‐Ju Yang, Hsiang‐Tai Chao, Jen‐Chuen Hsieh · 2017 · Scientific Reports
- CD4+ αβ T cell infiltration into the leptomeninges of lumbar dorsal roots contributes to the transition from acute to chronic mechanical allodynia after adult rat tibial nerve injuriesBin Du, You‐Quan Ding, Xia Xiao, Hong-Yi Ren, Bingyin Su, Jian‐Guo Qi · 2018 · Journal of Neuroinflammation
- Adverse childhood experience and adult persistent pain and disability: protocol for a systematic review and meta-analysisBussières, André, Hartvigsen, Jan, Ferreira, Manuela L., Ferreira, Paulo H., Hancock, Mark J., Stone, Laura S., Wideman, Timothy H., Boruff, Jill, Elklit, Ask · 2020 · Systematic Reviews
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- NAAA-regulated lipid signaling governs the transition from acute to chronic painYannick Fotio, Kwang‐Mook Jung, Francesca Palese, André Obenaus, Alex Mabou Tagne, Lin Lin, Tarif Ibne Rashid, Romario Pacheco, Amandine Jullienne, Jade Ramirez et al. · 2021 · Science Advances
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- A sociocultural neuroscience approach to painSteven R. Anderson, Elizabeth A. Reynolds Losin · 2016 · Culture and Brain
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- Reduced limbic microstructural integrity in functional neurological disorderIbai Palacio Diez, Benjamin Williams, Marek R. Kubicki, Nikos Makris, David L. Perez · 2019 · Psychological Medicine
- The association of early life stressors with pain sensitivity and pain experience at 22 yearsRobert Waller, Anne Julia Smith, Peter O’Sullivan, Helen Slater, Michele M. Sterling, Leon Melville Straker · 2019 · Pain
- Fear avoidance beliefs in back pain-free subjects are reflected by amygdala-cingulate responsesMichael Lukas Meier, Philipp Stämpfli, Andrea Vrana, Barry Kim Humphreys, Erich Seifritz, Sabina Hotz Boendermaker · 2015 · Frontiers in Human Neuroscience
- MicroRNA Circulating in the Early Aftermath of Motor Vehicle Collision Predict Persistent Pain Development and Suggest a Role for microRNA in Sex-Specific Pain DifferencesSarah D. Linnstaedt, Margaret G. Walker, Joel S. Parker, Eunice Yeh, Robert Sons, Erin Zimny, Christopher Lewandowski, Phyllis L. Hendry, Kathia Damiron, Claire Pearson et al. · 2015 · Molecular Pain
- Development of Cardiovascular Indices of Acute Pain Responding in Infants: A Systematic ReviewJordana A. Waxman, Rebecca Pillai Riddell, Paula Tablon Modica, Louis A. Schmidt, Angelina Pinhasov · 2016 · Pain Research and Management
- Amplified pain syndromes in childrenCara M. Hoffart, Dustin P. Wallace · 2014 · Current Opinion in Rheumatology
- Neurobiological basis for pain vulnerability: why me?Franziska Denk, Stephen Brendan McMahon · 2017 · Pain
- SIRT1 Decreases Emotional Pain Vulnerability with Associated CaMKIIα Deacetylation in Central AmygdalaChenghua Zhou, Yuqing Wu, Xiaobao Ding, Naihao Shi, Youqin Cai, Zhizhong Z. Pan · 2020 · Journal of Neuroscience
- Epigenetic upregulation of Cdk5 in the dorsal horn contributes to neuropathic pain in ratsKai Li, Guoqing Zhao, Longyun Li, Guangzhi Wu, Shusen Cui · 2014 · Neuroreport
- Molecular identification of bulbospinal ON neurons by GPER, which drives pain and morphine toleranceYingfu Jiao, Po Gao, Dong Li, Xiaowei Ding, Youqiang Meng, Jiahong Qian, Ting Gao, Ruoxi Wang, Tao Jiang, Yunchun Zhang et al. · 2022 · Journal of Clinical Investigation
- Skin-to-skin contact—An effective intervention on pain and stress reduction in preterm infantsHalyna Pavlyshyn, Iryna Sarapuk · 2023 · Frontiers in Pediatrics
- When thinking about pain contributes to suffering: the example of pain catastrophizingJennifer A. Haythornthwaite, Claudia M. Campbell, Robert Randolph Edwards · 2024 · Pain
- Chronic post-surgical pain after total knee arthroplasty: a narrative reviewDan Luo, Zhidong Fan, Wenqin Yin · 2024 · Perioperative Medicine
- MicroRNA 320a Predicts Chronic Axial and Widespread Pain Development Following Motor Vehicle Collision in a Stress-Dependent MannerSarah D. Linnstaedt, Kyle D. Riker, Margaret G. Walker, Jennifer E. Nyland, Erin Zimny, Christopher Lewandowski, Phyllis L. Hendry, Kathia Damiron, Claire Pearson, Marc‐Anthony Velilla et al. · 2016 · Journal of Orthopaedic and Sports Physical Therapy
- Neuroimaging enters the pain biomarker arenaIrene Tracey · 2021 · Science Translational Medicine
- Pain, from perception to action: A computational perspectiveZhe Sage Chen, Jing Wang · 2022 · iScience
- A cholinergic circuit that relieves pain despite opioid toleranceShivang Sullere, Alissa Kunczt, Daniel S. McGehee · 2023 · Neuron
- Loss in Executive Functioning Best Explains Changes in Pain Responsiveness in Patients with Dementia-Related Cognitive DeclineMiriam Kunz A, Veit Mylius, Karsten Schepelmann, Stefan Lautenbacher · 2015 · Behavioural Neurology
- Strategy-dependent modulation of cortical pain circuits for the attenuation of pain.E. Schulz, A. Stankewitz, V. Witkovský, A. Winkler, I. Tracey · 2019 · Cortex; a journal devoted to the study of the nervous system and behavior
- Identification of novel common variants associated with chronic pain using conditional false discovery rate analysis with major depressive disorder and assessment of pleiotropic effects of LRFN5Keira J.A. Johnston, Mark J. Adams, Barbara I. Nicholl, Joey Ward, Rona J. Strawbridge, Andrew Mark McIntosh, Daniel J. Smıth, Mark E.S. Bailey · 2019 · Translational Psychiatry
- Microglia: sculptors of neuropathic pain?Harry L Ward, Steven Jon West · 2020 · Royal Society Open Science
- A vision for the future of wearable sensors in spine care and its challenges: narrative reviewPaul W. Hodges, Wolbert van den Hoorn · 2021 · Journal of Spine Surgery
- Test–retest reliability of evoked heat stimulation BOLD fMRIJaymin Upadhyay, Jordan D. Lemme, Julie Anderson, David Bleakman, Thomas H. Large, Jeffrey L. Evelhoch, Richard J Hargreaves, David Borsook, Lino R. Becerra · 2015 · Journal of Neuroscience Methods
- Pain (and pleasure) in marketing and consumption: An integrative literature review and directions for future researchMinas N. Kastanakis, Σόλων Μαγρίζος, Katerina Kampouri · 2021 · Journal of Business Research
- Primary Role of the Amygdala in Spontaneous Inflammatory Pain- Associated Activation of Pain Networks – A Chemogenetic Manganese-Enhanced MRI ApproachDaigo Arimura, Kei Shinohara, Yukari Takahashi, Yae K. Sugimura, Mariko Sugimoto, Tomokazu Tsurugizawa, Keishi Marumo, Fusao Kato · 2019 · Frontiers in Neural Circuits
- Hypothyroidism and somatization: results from E-Mode patient self-assessment of thyroid therapy, a cross-sectional, International Online Patient SurveyPerros, Petros, Nagy, Endre Vezekenyi, Papini, Enrico, Van Der Feltz-Cornelis, Christina Maria, Weetman, Anthony Peter, Hay, Harriet Alexandra, Abad-Madroñero, Juan, Tallett, Amy Johanna, Bilas, Megan, Lakwijk, Peter et al. · 2023 · Thyroid
- The Role of The Rostral Ventromedial Medulla in Stress ResponsesMarco Pagliusi, Felipe V. Gomes · 2023 · Brain Sciences
- Epigenome-wide DNA methylation profiling of conditioned pain modulation in individuals with non-specific chronic low back painBurel R. Goodin, Demario S. Overstreet, Terence M. Penn, Rahm J. Bakshi, Tammie L. Quinn, Andrew Sims, Travis Ptacek, Pamela Jackson, D. Leann Long, Edwin N. Aroke · 2022 · Clinical Epigenetics
- Central sensitization-related changes of effective and functional connectivity in the rat inflammatory trigeminal pain modelTamás Spisák, Zsófia Pozsgay, Csaba Aranyi, Szabolcs Dávid, Pál Kocsis, Gabriella Nyitrai, Dávid Gajári, Miklós Emri, András Czurkó, Zsigmond Tamás Kincses · 2016 · Neuroscience
- Neuroimaging Studies of Primary DysmenorrheaIntan Low, Shyh‐Yuh Wei, Pin-Shiuan Lee, Wei‐Chi Li, Lin-Chien Lee, Jen‐Chuen Hsieh, Li‐Fen Chen · 2018 · Advances in experimental medicine and biology
- Nociception and PainCarolyn M. McKune, Joanna C. Murrell, Andrea Mary Nolan, Kate White, Bonnie D. Wright · 2015
- Persistent inflammatory pain is linked with anxiety-like behaviors, increased blood corticosterone, and reduced global DNA methylation in the rat amygdalaRichard L. Spinieli, Rafael Alves Cazuza, Amanda J. Sales, Ruither Oliveira Gomes Carolino, Diana Martinez, Janete Aparecida Anselmo‐Franci, Maral Tajerian, Christie Ramos Andrade Leite‐Panissi · 2022 · Molecular Pain
- A vulnerability to chronic pain and its interrelationship with resistance to analgesiaIrene Tracey · 2016 · Brain
- Pain-sensorimotor interactions: New perspectives and a new modelGreg M. Murray, Barry John Sessle · 2024 · Neurobiology of Pain
- Contribution of mesolimbic dopamine and kappa opioid systems to the transition from acute to chronic painFernanda Vergara, Natalia Fantin Sardi, Ana Carolina Pescador, Gisele Oliveira Guaita, Cristina Aparecida Jark Stern, Juliana Geremias Chichorro, Luana Fischer · 2020 · Neuropharmacology
- Neuromodulatory Signaling in Chronic Pain Patients: A Narrative ReviewGiustino Varrassi, Matteo Luigi Giuseppe Leoni, Giacomo Farì, Ameen Abdulhasan Al-Alwany, Sarah Al Sharie, Diego Fornasari · 2025 · Cells
- Quantifying Blood-Spinal Cord Barrier Permeability after Peripheral Nerve Injury in the Living MouseLindsay S. Cahill, Christine L. Laliberté, Xue Jun Liu, Jonathan E. Bishop, Brian J. Nieman, Jeffrey S. Mogil, Robert E. Sorge, Catherine Danielle Jones, Michael W. Salter, R. Mark Henkelman · 2014 · Molecular Pain
- Brain Connectivity Predicts Chronic Pain in Acute Mild Traumatic Brain InjuryNoam Bosak, Paulo Branco, Pora Kuperman, Chen Buxbaum, Ruth Manor Cohen, Shiri Fadel, Rabab Zubeidat, Rafi Hadad, Amir Lawen, Noam Saadon‐Grosman et al. · 2022 · Annals of Neurology
- Conditioned pain modulation is associated with heightened connectivity between the periaqueductal grey and cortical regionsRichard Neil Harrison, Wiebke Gandhi, Carien M. van Reekum, Tim Vaughn Salomons · 2022 · PAIN Reports
- The effect of mindfulness on the inflammatory, psychological and biomechanical domains of adult patients with low back pain: A randomized controlled clinical trialGustavo G. Díez, Eduardo Anitua, Nazareth P. Castellanos, Carmelo Vázquez, Purificación Galindo‐Villardón, Mohammad Hamdan Alkhraisat · 2022 · PLoS ONE
- Pain vulnerability and DNA methyltransferase 3a involved in the affective dimension of chronic painWei Wang, Caiyue Li, Youqing Cai, Zhizhong Z. Pan · 2017 · Molecular Pain
- Repurposing of Tranilast for Potential Neuropathic Pain Treatment by Inhibition of Sepiapterin Reductase in the BH4 PathwayBenjamin J. R. Moore, Barira Islam, Sean Ward, Olivia Jackson, Rebecca Armitage, Jack Blackburn, Shozeb M Haider, Patrick McHugh · 2019 · ACS Omega
- Improving neuropathic pain treatment – by rigorous stratification from bench to bedsideNadia Soliman, Dilara Kersebaum, Timothy Lawn, Juliane Sachau, Manon Sendel, Jan Vollert · 2023 · Journal of Neurochemistry
- Epigenetic modulation of Wnt signaling contributes to neuropathic pain in ratsWei Feng, RUYNAG TENG, Yang Zhao, JIE GAO, Haichen Chu · 2015 · Molecular Medicine Reports
- Transition from Acute to Chronic Pain: Where Cells, Systems and Society MeetGlare, Paul, Overton, Sarah, Aubrey, Karin · 2020 · Pain Management
- Neurochemical dynamics of acute orofacial pain in the human trigeminal brainstem nuclear complexNuno M.P. de Matos, Andreas Hock, Michael Wyss, Dominik Alois Ettlin, Mike Brügger · 2017 · NeuroImage
- Genetic and epigenetic mechanisms influencing acute to chronic postsurgical pain transitions in pediatrics: Preclinical to clinical evidenceAdam J. Dourson, Adam Willits, Namrata G.R. Raut, Leena Kader, Erin E. Young, Michael P. Jankowski, Vidya Chidambaran · 2022 · Canadian Journal of Pain
- Early life inflammation is associated with spinal cord excitability and nociceptive sensitivity in human infantsMaría Mercedes Cobo, Gabrielle Green, Foteini Andritsou, Luke Baxter, Ria Evans Fry, Annika Grabbe, Deniz Gursul, Amy Hoskin, Gabriela Schmidt Mellado, Marianne van der Vaart et al. · 2022 · Nature Communications
- Midbrain glutamatergic circuit mechanism of resilience to socially transferred allodynia in male miceYi Han, Lin Ai, Lingzhen Song, Yu Zhou, Dandan Chen, Sha Sha, Ran Ji, Qize Li, Qingyang Bu, Xiangyu Pan et al. · 2024 · Nature Communications
- The dorsal posterior insula is not an island in pain but subserves a fundamental role - Response to: “Evidence against pain specificity in the dorsal posterior insula” by Davis et al.Andrew R. Segerdahl, Melvin Mezue, Thomas W. Okell, John T. Farrar, Irene Tracey · 2015 · F1000Research
- Common Pediatric Pain Disorders and Their Clinical AssociationsTheresa J. Donnelly, Aneeka Bott, Minh Bui, Shuxiang Goh, Tiina Jaaniste, Cindy Chapman, Matthew Crawford, John Llewelyn Hopper, G. David Champion · 2017 · Clinical Journal of Pain
- Low-threshold mechanoreceptors play a frequency-dependent dual role in subjective ratings of mechanical allodyniaLine S. Löken, Eugene Paul Duff, Irene Tracey · 2017 · Journal of Neurophysiology
- Risikostratifizierung bezüglich der Entwicklung von chronischem postoperativem SchmerzStephan Alexander Schug, Julie Bruce · 2018 · Der Schmerz
- G-Protein-Coupled Estrogen Receptor (GPER) in the Rostral Ventromedial Medulla Is Essential for Mobilizing Descending Inhibition of ItchTing Gao, Dong Li, Jiahong Qian, Xiaowei Ding, Yi Zheng, Meimei Wu, Li Meng, Yingfu Jiao, Po Gao, Ping Luo et al. · 2021 · Journal of Neuroscience
- Environmental factors and their impact on chronic pain development and maintenanceMorena Brazil Sant’Anna, Louise Faggionato Kimura, Willians Fernando Vieira, Vanessa O. Zambelli, Leonardo Santana Novaes, Natália Gabriele Hösch, Gisele Picolo · 2024 · Physics of Life Reviews
- Hormonal Contraceptive Treatment May Reduce the Risk of Fibromyalgia in Women with Dysmenorrhea: A Cohort StudyCheng‐Hao Tu, Cheng‐Li Lin, Su‐Tso Yang, Wei‐Chih Shen, Yi‐Hung Chen · 2020 · Journal of Personalized Medicine
- The Prediction of Acute Postoperative Pain Based on Neural Oscillations Measured before the SurgeryQi Han, Lupeng Yue, Fei Gao, Libo Zhang, Li Hu, Yi Feng · 2021 · Neural Plasticity
- Functional and diffusion MRI reveal the neurophysiological basis of neonates’ noxious-stimulus evoked brain activityLuke Baxter, Fiona Moultrie, Sean P. Fitzgibbon, Marianne Aspbury, Roshni C. Mansfield, Matteo Bastiani, Richard Rogers, Saâd Jbabdi, Eugene Paul Duff, Rebeccah Slater · 2021 · Nature Communications
- Early Life Pain Experience Changes Adult Functional Pain Connectivity in the Rat Somatosensory and the Medial Prefrontal CortexPishan Chang, Lorenzo Fabrizi D, Maria Fitzgerald · 2022 · Journal of Neuroscience
- Beyond biopsychosocial: The keystone mechanism theory of painTimothy Lawn, Manon Sendel, Ralf Baron, Jan Vollert · 2023 · Brain Behavior and Immunity
- Psychosocial and cardiometabolic predictors of chronic pain onset in Native Americans: serial mediation analyses of 2-year prospective data from the Oklahoma Study of Native American Pain RiskJamie L. Rhudy, Felicitas A. Huber, Tyler A. Toledo, Parker A. Kell, Erin N. Street, Joanna O. Shadlow · 2021 · Pain
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- The influence of High Dose Spinal Cord Stimulation on the descending pain modulatory system in patients with failed back surgery syndromeSander De Groote, Lisa Goudman, Ronald R. Peeters, Bengt Linderoth, Peter Van Schuerbeek, Stefan G. Sunaert, Mats De Jaeger, Ann De Smedt, José Antonio De Andrés, Maarten Moens · 2019 · NeuroImage Clinical
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- A multidisciplinary assessment of pain in juvenile idiopathic arthritisJaymin Upadhyay, Jordan D. Lemme, Mariesa Cay, Hanne C. van der Heijden, Diana Sibai, Benjamin D. Goodlett, Jeffery Lo, Kacie J. Hoyt, Maria L. Taylor, Melissa M. Hazen et al. · 2021 · Seminars in Arthritis and Rheumatism
- The Role of Positive Psychological Factors in the Association between Pain Intensity and Pain Interference in Individuals with Chronic Musculoskeletal Pain: A Cross-Sectional StudyJavier Martínez-Calderón, Mar Flores-Cortés, Susana Clavero-Cano, José Miguel Morales‐Asencio, Mark P. Jensen, Antonio Rondón-Ramos, Juan Luis Díaz-Cerrillo, Gina Rocío Ariza-Hurtado, Alejandro Luque-Suárez · 2020 · Journal of Clinical Medicine
- Involvement of P2X7 Receptors and BDNF in the Pathogenesis of Central Poststroke PainYung‐Hui Kuan, Hsi-Chien Shih, Bai‐Chuang Shyu · 2018 · Advances in experimental medicine and biology
- MHCII-restricted T helper cells: an emerging trigger for chronic tactile allodynia after nerve injuriesYou‐Quan Ding, Han Luo, Jian‐Guo Qi · 2020 · Journal of Neuroinflammation
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