Single App knock-in mouse models of Alzheimer’s disease

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Items 1,001–1,100 of 1,333

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  4. Alzheimer’s Disease
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  6. Research on the Pros and Cons of the Mouse Model of Alzheimer’s Disease
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  9. A rat model established by simulating genetic–environmental interactions recapitulates human Alzheimer's disease pathology
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  10. Dysfunctional Bladder Morphology and Functional Impairments Are Identified in the Alzheimer’s Disease APPNL-G-F/NL-G-F Murine Model
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  11. Precipitation of Insoluble Fibrin in the Brains of Alzheimer’s Disease Model Mice
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  12. Evaluating the Therapeutic Effect of an Hsp90 Inhibitor in Mouse Models of Alzheimer’s Disease
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  15. The AppNL-G-F mouse model of Alzheimer’s disease is refractory to regulatory T cell treatment
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  16. Gradual cerebral hypoperfusion in a knock-in mouse model of Alzheimer’s disease triggers cortical network dysfunctions
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  17. In vivo Protein Footprinting Reveals the Dynamic Conformational Changes of Proteome of Multiple Tissues in Progressing Alzheimer’s Disease
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  18. Cuprizone drives divergent neuropathological changes in different mouse models of Alzheimer’s disease
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  19. Uncoupling of synaptic loss from amyloid burden by an Alzheimer’s disease protective variant of PLCγ2
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  22. Age- and amyloid-β-dependent initiation of neurofibrillary tau tangles: NLFTau m/h , an improved mouse model of Alzheimer’s disease without mutations in MAPT
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  23. Alzheimer’s Disease Mutations Disrupt Neural Stem Cell Fate and Early Brain Development
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  24. Misclassification in memory modification in AppNL-G-F knock-in mouse model of Alzheimer’s disease
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  25. Proteomic characterization of neuronal extracellular vesicle interactomes in Alzheimer’s disease mouse model through TurboID-based proximity labeling
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  26. APP accumulates around dense-core amyloid plaques with presynaptic proteins in Alzheimer’s disease brain
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  28. Single Plaque Proteomics Reveals the Composition and Dynamics of the Amyloid Microenvironment in Alzheimer’s Disease
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  29. Long Wake/Short Sleep Bouts and Hyperactivity with Advanced Age in a Mouse Model of Early Onset Alzheimer’s Disease
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  30. Astrocyte-neuron mitochondrial transfer via mitoEVs supports neuronal energy metabolism and is impaired in early Alzheimer’s disease
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  31. Early memory deficits and extensive brain network disorganization in the AppNL-F/MAPT double knock-in mouse model of familial Alzheimer's disease
    Christopher Borcuk · 2021 · theses.fr (ABES)
  32. Therapeutic targeting of fibrin–microglia interactions ameliorates Alzheimer’s disease-related hyperexcitability and brain network dysfunction
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  33. Characterization of the knock-in App SAA mouse model as a powerful tool for Alzheimer’s disease preclinical research
    Lucy J. Sloan, Dylan T. Garceau, Nick Ryan, Justice Pomeroy-Tuck, Ritesh Chidambaram, Tim Ragan, Ravi S. Pandey, Erik B. Bloss, Gregory W. Carter, Adrian L. Oblak et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  34. Alzheimer’s Disease and Frontotemporal Lobar Degeneration: Mouse Models
    Janet van Eersel, Fabien Delerue, Lars Matthias Ittner, Yazi Diana Ke · 2014 · Springer eBooks
  35. Genome Editing in Mice Using TALENs
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  36. Past, Present, and Future: The Behavioral Sciences.
    John G. Darley · 1971 · Contemporary Psychology
  37. Using TUDCA to treat Alzheimer's disease after pathology onset in APP/PS1 mice
    Pedro Dionísio · 2014 · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
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    Faculdade De Farmácia · 2014
  40. Application of tissue-clearing methods for dissecting brain structure
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  41. Analysis of protein SUMOylation and its role in Alzheimer's disease using mouse models
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  42. AN ISOGENIC STEM CELL MODEL OF ALZHEIMER'S DISEASE: DIRECT EXPRESSION OF AMYLOID-BETA
    Teresa Ubina · 2017 · CSUSB ScholarWorks (California State University, San Bernardino)
  43. A variant of the Morris water task for assessing learning and memory processes in mice
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  44. FENS ‐Kavli winter symposium: Addressing the cellular phase of dementia—visions of the UK Dementia Research Institute
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  45. Multidimensional dynamics of the proteome in the neurodegenerative and ageing mammalian brain
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  46. Development of Artificial Catalysts that Selectively Photooxygenate Pathogenic Amyloid
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  47. Exploring the Role of Somatostatin in the Pathogenesis of Alzheimer’s disease
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  48. An inducible and reversible genetics platform for novel drug target discovery
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  49. Isolation housing exacerbates Alzheimer’s Disease phenotype in aged APP KI mice
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  50. The Propagation of Neurodegenerative Diseases by Inflammation and Exosomes
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  51. Amyloid Precursor Protein (APP) processing and potential targets for Alzheimer’s Disease
    Andrew B. Bonner · 2019 · Biomedical Genetics and Genomics
  52. Melanin Concentrating Hormone- and sleep-dependent synaptic downscaling is impaired in Alzheimer’s Disease
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  54. A tetracycline antibiotic minocycline prevents early aging phenotypes in mice heterozygous for RP58
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  60. Early Tactile Stimulation Influences the Development of Alzheimer Disease in Gestationally Stressed APP Nl-G-F Adult Offspring Nl-G-F/Nl-G-F Mice
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  61. circAβ RNA drives the formation and deposition of β-amyloid plaques in the sporadic Alzheimer’s disease
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  62. Effekte von chronischer Hyperhomocysteinämie und spezifischen Mikronährstoff-Interventionen auf die kognitive Leistungsfähigkeit im AppNL-G-F knock-in Mausmodell der Alzheimer-Erkrankung
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  63. Therapeutic and immunomodulatory functions of the translocator protein in Alzheimer's disease
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  65. Generation of a hybrid App NL-G-F/NL-G-F × Thy1 -GCaMP6s +/- Alzheimer disease mouse mitigates the behavioral and hippocampal encoding deficits of APP knock-in mutations of App NL-G-F/NL-G-F mice
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  81. Aβ-driven nuclear pore complex dysfunction alters activation of necroptosis proteins in a mouse model of Alzheimer’s Disease
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  86. Additional file 1 of Neuronal transcriptome, tau and synapse loss in Alzheimer’s knock-in mice require prion protein
    Austin J. Stoner, Li Fu, LaShae Nicholson, Chao Zheng, Takuya Toyonaga, Joshua M. Spurrier, Will Laird, Zhengxin Cai, Stephen M. Strittmatter · 2023 · Figshare
  87. Additional file 3 of Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity
    Arun Upadhyay, Deepak Chhangani, Nalini R. Rao, Julia Kofler, Robert J. Vassar, Diego E. Rincón-Limas, Jeffrey N. Savas · 2023 · Figshare
  88. Additional file 1 of Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis
    Richeng Jiang, Una Smailović, Hazal Haytural, Betty Marije Tijms, Hao Li, Robert Mihai Haret, Ganna Shevchenko, Gefei Chen, Axel Abelein, Johan Gobom et al. · 2022 · Figshare
  89. Additional file 7 of Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis
    Richeng Jiang, Una Smailović, Hazal Haytural, Betty Marije Tijms, Hao Li, Robert Mihai Haret, Ganna Shevchenko, Gefei Chen, Axel Abelein, Johan Gobom et al. · 2022 · Figshare
  90. Additional file 8 of Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis
    Richeng Jiang, Una Smailović, Hazal Haytural, Betty Marije Tijms, Hao Li, Robert Mihai Haret, Ganna Shevchenko, Gefei Chen, Axel Abelein, Johan Gobom et al. · 2022 · Figshare
  91. Additional file 6 of Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity
    Arun Upadhyay, Deepak Chhangani, Nalini R. Rao, Julia Kofler, Robert J. Vassar, Diego E. Rincón-Limas, Jeffrey N. Savas · 2023 · Figshare
  92. Additional file 2 of Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis
    Richeng Jiang, Una Smailović, Hazal Haytural, Betty Marije Tijms, Hao Li, Robert Mihai Haret, Ganna Shevchenko, Gefei Chen, Axel Abelein, Johan Gobom et al. · 2022 · Figshare
  93. Additional file 9 of Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity
    Arun Upadhyay, Deepak Chhangani, Nalini R. Rao, Julia Kofler, Robert J. Vassar, Diego E. Rincón-Limas, Jeffrey N. Savas · 2023 · Figshare
  94. Additional file 4 of Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity
    Arun Upadhyay, Deepak Chhangani, Nalini R. Rao, Julia Kofler, Robert J. Vassar, Diego E. Rincón-Limas, Jeffrey N. Savas · 2023 · Figshare
  95. Additional file 5 of Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity
    Arun Upadhyay, Deepak Chhangani, Nalini R. Rao, Julia Kofler, Robert J. Vassar, Diego E. Rincón-Limas, Jeffrey N. Savas · 2023 · Figshare
  96. Additional file 8 of Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity
    Arun Upadhyay, Deepak Chhangani, Nalini R. Rao, Julia Kofler, Robert J. Vassar, Diego E. Rincón-Limas, Jeffrey N. Savas · 2023 · Figshare
  97. Additional file 7 of Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity
    Arun Upadhyay, Deepak Chhangani, Nalini R. Rao, Julia Kofler, Robert J. Vassar, Diego E. Rincón-Limas, Jeffrey N. Savas · 2023 · Figshare
  98. Additional file 5 of Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis
    Richeng Jiang, Una Smailović, Hazal Haytural, Betty Marije Tijms, Hao Li, Robert Mihai Haret, Ganna Shevchenko, Gefei Chen, Axel Abelein, Johan Gobom et al. · 2022 · Figshare
  99. Plaque-associated endogenous IgG and its impact on immunohistochemical detection of mouse monoclonal IgG antibodies in mouse models of Alzheimer’s disease
    Shogo Ito, Kenta Yamauchi, Hiroshi Hama, Masato Koike, Atsushi Miyawaki, Hiroyuki Hioki · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  100. Aβ-driven nuclear pore complex dysfunction alters activation of necroptosis proteins in a mouse model of Alzheimer’s Disease
    Vibhavari Aysha Bansal, Jia Min Tan, Hui Rong Soon, Norliyana Zainolabidin, Takashi Saito, Toh Hean Ch’ng · 2024 · eLife