Itohara, Shigeyoshi

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

Bergers, G., Brekken, R., McMahon, G., Vu, T. H., Itoh, T., Tamaki, K., Tanzawa, K., Thorpe, P., Itohara, S., Werb, Z., et al. (2000) · Nature Cell Biology

Angiogenesis and VEGF in CancerProtease and Inhibitor Mechanisms

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Single App knock-in mouse models of Alzheimer’s disease

Saito, T., Matsuba, Y., Mihira, N., Takano, J., Nilsson, P., Itohara, S., Iwata, N., & Saido, T. C. (2014) · Nature Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

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Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain

Imayoshi, I., Sakamoto, M., Ohtsuka, T., Takao, K., Miyakawa, T., Yamaguchi, M., Mori, K., Ikeda, T., Itohara, S., & Kageyama, R. (2008) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

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Nav1.1 Localizes to Axons of Parvalbumin-Positive Inhibitory Interneurons: A Circuit Basis for Epileptic Seizures in Mice Carrying an Scn1a Gene Mutation

Ogiwara, I., Miyamoto, H., Morita, N., Atapour, N., Mazaki, E., Inoue, I., Takeuchi, T., Itohara, S., Yanagawa, Y., Obata, K., et al. (2007) · The Journal of Neuroscience

Epilepsy research and treatmentIon channel regulation and function

Cited by 879

The Membrane-Anchored MMP Inhibitor RECK Is a Key Regulator of Extracellular Matrix Integrity and Angiogenesis

Oh, J., Takahashi, R., Kondo, S., Mizoguchi, A., Adachi, E., Sasahara, R. M., Nishimura, S., Imamura, Y., Kitayama, H., Alexander, D. B., et al. (2001) · Cell

Protease and Inhibitor MechanismsTGF-β signaling in diseases

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Ventral CA1 neurons store social memory

Okuyama, T., Kitamura, T., Roy, D. S., Itohara, S., & Tonegawa, S. (2016) · Science

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 657

Mutant Mice and Neuroscience: Recommendations Concerning Genetic Background

Silva, A. J., Simpson, E. M., Takahashi, J. S., Lipp, H.-P., Nakanishi, S., Wehner, J. M., Giese, K. P., Tully, T., Abel, T., Chapman, P. F., et al. (1997) · Neuron

Animal Genetics and ReproductionMemory and Neural Mechanisms

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Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions

Gomi, H., Yokoyama, T., Fujimoto, K., Ikeda, T., Katoh, A., Itoh, T., & Itohara, S. (1995) · Neuron

Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments

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Cognitive deficits in single App knock-in mouse models

Masuda, A., Kobayashi, Y., Kogo, N., Saito, T., Saido, T. C., & Itohara, S. (2016) · Neurobiology of Learning and Memory

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 248

Autistic-like phenotypes in Cadps2-knockout mice and aberrant CADPS2 splicing in autistic patients

Sadakata, T., Washida, M., Iwayama, Y., Shoji, S., Sato, Y., Ohkura, T., Katoh-Semba, R., Nakajima, M., Sekine, Y., Tanaka, M., et al. (2007) · Journal of Clinical Investigation

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

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GABAergic Control of Adult Hippocampal Neurogenesis in Relation to Behavior Indicative of Trait Anxiety and Depression States

Earnheart, J. C., Schweizer, C., Crestani, F., Iwasato, T., Itohara, S., Mohler, H., & Lüscher, B. (2007) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 203

S100B is increased in Parkinson’s disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-α pathway

Sathe, K., Maetzler, W., Lang, J. D., Mounsey, R. B., Fleckenstein, C., Martin, H. L., Schulte, C., Mustafa, S., Synofzik, M., Vukovic, Z., et al. (2012) · Brain

Parkinson's Disease Mechanisms and TreatmentsS100 Proteins and Annexins

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Targeted disruption of the mouse 3-phosphoglycerate dehydrogenase gene causes severe neurodevelopmental defects and results in embryonic lethality

Yoshida, K., Furuya, S., Osuka, S., Mitoma, J., Shinoda, Y., Watanabe, M., Azuma, N., Tanaka, H., Hashikawa, T., Itohara, S., et al. (2004) · Journal of Biological Chemistry

Amino Acid Enzymes and MetabolismNeurogenesis and neuroplasticity mechanisms

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Axonal netrin-Gs transneuronally determine lamina-specific subdendritic segments

Nishimura-Akiyoshi, S., Niimi, K., Nakashiba, T., & Itohara, S. (2007) · Proceedings of the National Academy of Sciences

Axon Guidance and Neuronal SignalingNeuroscience and Neuropharmacology Research

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RacGAP α2-Chimaerin Function in Development Adjusts Cognitive Ability in Adulthood

Iwata, R., Ohi, K., Kobayashi, Y., Masuda, A., Iwama, M., Yasuda, Y., Yamamori, H., Tanaka, M., Hashimoto, R., Itohara, S., et al. (2014) · Cell Reports

Memory and Neural MechanismsNeurogenesis and neuroplasticity mechanisms

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Monoclonal antibodies discriminating netrin-G1 and netrin-G2 neuronal pathways

Niimi, K., Nishimura-Akiyoshi, S., Nakashiba, T., & Itohara, S. (2007) · Journal of Neuroimmunology

Axon Guidance and Neuronal SignalingDevelopmental Biology and Gene Regulation

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