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A neuromarker of sustained attention from whole-brain functional connectivity

Open access
Rosenberg, Monica D, Finn, Emily S, Scheinost, Dustin, Papademetris, Xenophon, Shen, Xilin, Constable, R Todd, Chun, Marvin M·2016·Nature Neuroscience

Abstract

Although attention plays a ubiquitous role in perception and cognition, researchers lack a simple way to measure a person's overall attentional abilities. Because behavioral measures are diverse and difficult to standardize, we pursued a neuromarker of an important aspect of attention, sustained attention, using functional magnetic resonance imaging. To this end, we identified functional brain networks whose strength during a sustained attention task predicted individual differences in performance. Models based on these networks generalized to previously unseen individuals, even predicting performance from resting-state connectivity alone. Furthermore, these same models predicted a clinical measure of attention—symptoms of attention deficit hyperactivity disorder—from resting-state connectivity in an independent sample of children and adolescents. These results demonstrate that whole-brain functional network strength provides a broadly applicable neuromarker of sustained attention.

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Metadata

Authors
Rosenberg, M. D., Finn, E. S., Scheinost, D., Papademetris, X., Shen, X., Constable, R. T., & Chun, M. M.
Venue
Nature Neuroscience
Published
2015-11-23
Volume
19
Issue
1
Pages
165-171
ISSN
  • 1097-6256 (ISSN-L)
  • 1546-1726
OpenAlex
W2174056659
Cited by
1,014
References
52
FWCI
29.32
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: A neuromarker of sustained attention from whole-brain functional connectivity. https://app.cochat.ai/papers/10.1038/nn.4179
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Rosenberg, M. D., Finn, E. S., Scheinost, D., Papademetris, X., Shen, X., Constable, R. T., & Chun, M. M. (2016). A neuromarker of sustained attention from whole-brain functional connectivity. Nature Neuroscience. https://doi.org/10.1038/nn.4179

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