Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice

Langfelder, Peter, Cantle, Jeffrey P, Chatzopoulou, Doxa, Wang, Nan, Gao, Fuying, Al-Ramahi, Ismael, Lu, Xiao-Hong, Ramos, Eliana Marisa +14 more·2016·Nature Neuroscience

DOI 10.1038/nn.4256

Cited by (408)

Items 101–200 of 408

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Carlos Estevez‐Fraga, André Altmann, Christopher S Parker, Rachael I. Scahill, Beatrice Costa, Zhongbo Chen, Claudia Manzoni, Angeliki Zarkali, Alexandra Dürr, Raymund A.C. Roos et al. · 2023 · Brain
Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models
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Proteomic Analysis of Huntington’s Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets
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Su Yang, Huiming Yang, Luoxiu Huang, Luxiao Chen, Zhaohui Steve Qin, Shihua Li, Xiao‐Jiang Li · 2020 · Proceedings of the National Academy of Sciences
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Jae Wook Hyeon, Albert H. Kim, Hiroko Yano · 2021 · Neurochemistry International
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Tamara Ratovitski, Raghothama Chaerkady, Kai Kammers, Jacqueline C. Stewart, Anialak Zavala, Olga Pletniková, Juan Carlos Troncoso, Dobrila D. Rudnicki, Russell L. Margolis, Robert Norman Cole et al. · 2016 · Journal of Proteome Research
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Buck, Eva, Bayer, Hanna, Lindenberg, Katrin S., Hanselmann, Johannes, Pasquarelli, Noemi, Ludolph, Albert C., Weydt, Patrick, Witting, Anke · 2017 · Frontiers in Molecular Neuroscience
Transcriptional Dysregulation in Huntington’s Disease: The Role in Pathogenesis and Potency for Pharmacological Targeting
Aleksandra Pogoda-Wesołowska, Natalia Chmielewska, Piotr Maciejak, Janusz Szyndler · 2020 · Current Medicinal Chemistry
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Manuela Bozzi, Francesca Sciandra · 2020 · International Journal of Molecular Sciences
Huntington’s disease mouse models: unraveling the pathology caused by CAG repeat expansion
Julia Kaye, Terry Reisine, Steven M. Finkbeiner · 2021 · Faculty Reviews
Deletion of SUMO1 attenuates behavioral and anatomical deficits by regulating autophagic activities in Huntington disease
Uri Nimrod Ramírez-Jarquín, Manish Sharma, Wuyue Zhou, Neelam Shahani, Srinivasa Subramaniam · 2022 · Proceedings of the National Academy of Sciences
Early detection of exon 1 huntingtin aggregation in zQ175 brains by molecular and histological approaches
Edward J. Smith, Kirupa Sathasivam, Christian Landles, Georgina F Osborne, Michael Atwood Mason, Casandra Gomez-Paredes, Bridget A. Taxy, Rebecca E Milton, Anne Ast, Franziska Schindler et al. · 2022 · Brain Communications
HttQ111/+ Huntington’s Disease Knock-in Mice Exhibit Brain Region-Specific Morphological Changes and Synaptic Dysfunction
Marina V. Kovalenko, Austen J. Milnerwood, James V. Giordano, Jason St. Claire, Jolene R. Guide, Mary Stromberg, Tammy Gillis, Ellen Sapp, Marian DiFiglia, Marcy E. MacDonald et al. · 2018 · Journal of Huntington s Disease
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Conformation Polymorphism of Polyglutamine Proteins
Xinran Feng, Shouqing Luo, Boxun Lu · 2018 · Trends in Biochemical Sciences
Protein changes in synaptosomes of Huntington's disease knock-in mice are dependent on age and brain region
Ellen Sapp, Connor Seeley, Maria Iuliano, Elizabeth Weisman, Petr Vodička, Marian DiFiglia, Kimberly B. Kegel-Gleason · 2020 · Neurobiology of Disease
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Guendalina Bergonzoni, Jessica Döring, Marta Biagioli · 2021 · Frontiers in Cellular Neuroscience
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Daniele Bertoglio, Jonathan Bard, Manuela Heßmann, Longbin Liu, Annette Gärtner, Stef De Lombaerde, Britta Huscher, Franziska Zajicek, Alan Miranda, Finn Peters et al. · 2022 · Science Translational Medicine
Differential Alteration in Expression of Striatal GABAAR Subunits in Mouse Models of Huntington’s Disease
Zhuowei Du, Margot Tertrais, Gilles Courtand, Thierry Lesté-Lasserre, Laura Cardoit, F. Masmejean, Christophe Halgand, Yoon H. Cho, Maurice Garret · 2017 · Frontiers in Molecular Neuroscience
Unsupervised discovery of phenotype-specific multi-omics networks
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Marija Fjodorova, Morgane Louessard, Zongze Li, Daniel Cabezas de la Fuente, Emma Dyke, Simon P. Brooks, Anselme L. Perrier, Meng Li · 2019 · Stem Cell Reports
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Andrea M. Reyes-Ortiz, Edsel M. Abud, Mara S. Burns, Jie Wu, Sarah J. Hernandez, Nicolette R. McClure, Keona Q. Wang, Corey J. Schulz, Ricardo Miramontes, Alice Lau et al. · 2022 · iScience
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Christian Landles, Georgina F Osborne, Jemima M Phillips, María Cañibano-Pico, Iulia M Nita, Nadira S. Ali, Konstantin Bobkov, Jonathan R. Greene, Kirupa Sathasivam, Gillian P. Bates · 2024 · Brain Communications
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Co-expression Patterns between ATN1 and ATXN2 Coincide with Brain Regions Affected in Huntington’s Disease
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