Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice
Langfelder, Peter, Cantle, Jeffrey P, Chatzopoulou, Doxa, Wang, Nan, Gao, Fuying, Al-Ramahi, Ismael, Lu, Xiao-Hong, Ramos, Eliana Marisa, El-Zein, Karla, Zhao, Yining, Deverasetty, Sandeep, Tebbe, Andreas, Schaab, Christoph, Lavery, Daniel J, Howland, David, Kwak, Seung, Botas, Juan, Aaronson, Jeffrey S, Rosinski, Jim, Coppola, Giovanni, Horvath, Steve, Yang, X William·2016·Nature Neuroscience
DOI 10.1038/nn.4256
Cited by (408)
Items 401–408 of 408
- Mathematical Models of Neurodegenerative Diseases: Principles, Applications, and InsightsSandeep Sathyanandan Nair, V. Srinivasa Chakravarthy, Aasef G. Shaikh · 2026 · Contemporary clinical neuroscience
- Temporal single-cell atlas of full-length Huntington’s disease mouse model defines stage-specific signatures of corticostriatal dysfunctionAshley B. Robbins, Paul T. Ranum, Icnelia Huerta-Ocampo, Michael Kuckyr, Beverly L. Davidson · 2026 · Molecular Neurodegeneration
- Mutant huntingtin disrupts TET1 transcription and alters DNA methylation in a Huntington’s disease knock-in pig modelLeijie Xie, Xiaodong Liu, Can Zhang, Xinyi Niu, Laiqiang Chen, Gongke Zhou, Mingyang Zhu, C Li, Huichun Tong, Sen Yan et al. · 2026 · Cell Reports
- Proteomic Impact of Peripheral Expression of Mutant Huntingtin in C. elegansEphraim Ezeigbo, Alyssa R. Stonebraker, herbi yuliantoro, Anjola Adewoye, Anthony DeBastiani, Emily Roefer, Pritom Kumar Biswas, Peng Li, Justin A. Legleiter, Stephen J. Valentine · 2026 · Journal of Proteome Research
- Isocaloric switch from low-fat to Western high-fat diet triggers transcriptomic reprogramming and ectopic olfactory receptor responsesJonathan Bertram, Michail Lazaratos, MICHAEL KRUSE, Silke Hornemann, Alexander Sandy Mosig, Turid Frahnow, Martin A. Osterhoff, Andreas Busjahn, Anne-Cathrin Ost, Annette Schürmann et al. · 2026 · Science Advances
- Dynamic Modulation of Neural Cell Identity Maintenance via Lysine Acetyltransferase Type 3 Protein Targeted DegradationJuan Zaragoza-Lillo, Sergio Niñerola, Verónica Estefania Andrade-Montero, Francisco José López-Murcia, Tania López-Hernández, Ángel Barco, Rafael Alcalá‐Vida · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Striatal astrocyte μ-crystallin (Crym) loss contributes to early-stage Huntington’s disease pathophysiologyMatthias Ollivier, Shengnan Xia, Neža Cankar, Filippa Liliendahl Qvist, Sara G. Pelaz, Chiranjivi Neupane, Vanessa L. Hull, Riki Kawaguchi, Niels Henning Skotte, Osama Al‐Dalahmah et al. · 2026 · Neuron
- The human-specific lncRNA HD-LINC drives lipid droplet-associated neurodegeneration in Huntington’s diseaseJi‐Sun Kwon, Liyuan Wang, Naga R. Ganti, Juncheng Li, Shengnan Xia, Osama Al‐Dalahmah, Andrew S.J. Yoo · 2026 · bioRxiv (Cold Spring Harbor Laboratory)