Inactivation of the central thalamus delays self-timed saccades
Open accessAbstract
The central thalamus transmits corollary discharge signals for eye movement control, but its role in eye movement generation remains uncertain. Inactivation of the paralaminar part of the ventrolateral thalamus delayed the initiation of contraversive saccades, particularly during a new memory-guided saccade task that required self-triggering of the movement. The results suggest that signals through the thalamus regulate the timing of self-initiated saccades.
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Corollary discharge has repeatedly been implicated in the process of updating the internal record of the current saccade to facilitate planning the next.
“CD has repeatedly been implicated in this process59–64.”
From Corollary discharge across the animal kingdom (2008) · cites this paper as [64]
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- Authors
- Tanaka, M.
- Affiliations
- Hokkaido University (JP)
- Corresponding author
- Tanaka, Masaki
- ORCID
- Tanaka, Masaki
- Venue
- Nature Neuroscience
- Published
- 2005-12-11
- Volume
- 9
- Issue
- 1
- Pages
- 20-22
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- OpenAlex
- W2061325097
- Cited by
- 54
- References
- 15
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 5 · 2023: 1 · 2021: 5 · 2020: 2 · 2019: 2 · 2018: 4 · 2017: 5 · 2016: 5 · 2015: 2 · 2014: 1 · 2013: 4 · 2012: 2
- FWCI
- 0.82
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Institutional Repositories DataBase (IRDB) (submittedVersion)
- Hokkaido University Collection of Scholarly and Academic Papers (Hokkaido University) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Keywords
- central thalamus, ventrolateral thalamic nucleus, saccade timing, memory-guided saccades, corollary discharge, oculomotor control, saccade initiation
- MeSH terms
- Animals, Haplorhini, Basal Ganglia, Cerebral Cortex, Fixation, Ocular, Memory, Photic Stimulation, Saccades, Thalamus, Ventral Thalamic Nuclei
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