Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

Yamanaka, Koji, Chun, Seung Joo, Boillee, Severine, Fujimori-Tonou, Noriko, Yamashita, Hirofumi, Gutmann, David H, Takahashi, Ryosuke, Misawa, Hidemi +1 more·2008·Nature Neuroscience

Cited by (1,000)

Items 501–600 of 1,000

  1. Group I metabotropic glutamate autoreceptors induce abnormal glutamate exocytosis in a mouse model of amyotrophic lateral sclerosis
    Francesco Giribaldi, Marco Milanese, Tiziana Bonifacino, Pia Irene Anna Rossi, Silvia Di Prisco, Anna Pittaluga, Carlo Tacchetti, Aldamaria Puliti, Cesare Usai, Giambattista Bonanno · 2012 · Neuropharmacology
  2. Emerging Roles of Filopodia and Dendritic Spines in Motoneuron Plasticity during Development and Disease
    Refik Kanjhan, Peter G. Noakes, Mark C. Bellingham · 2015 · Neural Plasticity
  3. AAV2/9-mediated overexpression of MIF inhibits SOD1 misfolding, delays disease onset, and extends survival in mouse models of ALS
    Marcel F. Leyton-Jaimes, Joy Kahn, Adrian Israelson · 2019 · Proceedings of the National Academy of Sciences
  4. Omics Approach to Axonal Dysfunction of Motor Neurons in Amyotrophic Lateral Sclerosis (ALS)
    Naoki Suzuki, Tetsuya Akiyama, Hitoshi Warita, Masashi Aoki · 2020 · Frontiers in Neuroscience
  5. Pathogenic mechanisms underlying spinocerebellar ataxia type 1
    Leon Tejwani, Janghoo Lim · 2020 · Cellular and Molecular Life Sciences
  6. Potential of activated microglia as a source of dysregulated extracellular microRNAs contributing to neurodegeneration in amyotrophic lateral sclerosis
    Eleni Christoforidou, Greig Joilin, Majid Hafezparast · 2020 · Journal of Neuroinflammation
  7. Differentiating human stem cells into neurons and glial cells for neural repair
    Vimal Selvaraj · 2011 · Frontiers in bioscience
  8. Primary Cilia in Glial Cells: An Oasis in the Journey to Overcoming Neurodegenerative Diseases
    Soo Mi Ki, Hui Su Jeong, Ji Eun Lee · 2021 · Frontiers in Neuroscience
  9. Safety and efficacy of first-in-man intrathecal injection of human astrocytes (AstroRx®) in ALS patients: phase I/IIa clinical trial results
    Marc Gotkine, Yoseph Caraco, Yossef Lerner, Simcha Blotnick, Maor Wanounou, Shalom Guy Slutsky, Judith Chebath, Graciela Kuperstein, Elena Estrin, Tamir Ben‐Hur et al. · 2023 · Journal of Translational Medicine
  10. δ‐Opioid receptors up‐regulate excitatory amino acid transporters in mouse astrocytes
    Jianfeng Liang, Dongman Chao, Harleen K. Sandhu, Yanbing Yu, Li Zhang, Gianfranco Balboni, Dong Kim, Ying Xia · 2014 · British Journal of Pharmacology
  11. The neuroprotective effect of the GSK-3β inhibitor and influence on the extrinsic apoptosis in the ALS transgenic mice
    Suk-Won Ahn, Jee‐Eun Kim, Kyung Seok Park, Won-Jun Choi, Yoon‐Ho Hong, Sung‐Min Kim, Seung Hyun Kim, Kwang Woo Lee, Jung‐Joon Sung · 2012 · Journal of the Neurological Sciences
  12. Astrocytes conspire with neurons during progression of neurological disease
    James C. McGann, Daniel T. Lioy, Gail Mandel · 2012 · Current Opinion in Neurobiology
  13. Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention
    Aaron Carman Sarah Kishinevsky, John Koren III Wenjie Lou · 2013 · Journal of Alzheimer’s Disease & Parkinsonism
  14. Concise Review: The Cellular Conspiracy of Amyotrophic Lateral Sclerosis
    Andrea Serio, Rickie Patani · 2017 · Stem Cells
  15. Mitochondrial Transport and Turnover in the Pathogenesis of Amyotrophic Lateral Sclerosis
    Veronica Granatiero, Giovanni Manfredi · 2019 · Biology
  16. Modeling Motor Neuron Resilience in ALS Using Stem Cells
    Ilary Allodi, Jik Nijssen, Julio Aguila Benitez, Christoph Schweingruber, Andrea Fuchs, Gillian Bonvicini, Ming Cao, Ole Kiehn, Eva Hedlund · 2019 · Stem Cell Reports
  17. Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1G93A astrocytes
    Veronica Granatiero, Nicole M. Sayles, Angela Maria Savino, Csaba Konràd, Michael G. Kharas, Hibiki Kawamata, Giovanni Manfredi · 2021 · Autophagy
  18. Nuclear Receptors, Inflammation, and Neurodegenerative Diseases
    Kaoru Saijo, Andrea Crotti, Christopher K. Glass · 2010 · Advances in immunology
  19. Reduced levels of interleukin 33 and increased levels of soluble ST2 in subjects with amyotrophic lateral sclerosis
    C.Y. Lin, Casey MM Pfluger, Robert D. Henderson, Pamela McCombe · 2012 · Journal of Neuroimmunology
  20. Caffeic acid phenethyl ester extends survival of a mouse model of amyotrophic lateral sclerosis
    Christine V. Fontanilla, X. Wei, Liming Zhao, Brian H. Johnstone, Robert M. Pascuzzi, Martin Rhys Farlow, Yansheng Du · 2011 · Neuroscience
  21. The Inflammatory Puzzle: Piecing together the Links between Neuroinflammation and Amyotrophic Lateral Sclerosis
    Di He, Yan Chun Xu, Mingsheng Liu, Liying Cui · 2023 · Aging and Disease
  22. ALS-related misfolded protein management in motor neurons and muscle cells
    M. Galbiati, V. Crippa, P. Rusmini, Riccardo Cristofani, M.E. Cicardi, Elisa Giorgetti, Elisa Onesto, Elio Messi, Angelo Poletti · 2014 · Neurochemistry International
  23. E6-AP association promotes SOD1 aggresomes degradation and suppresses toxicity
    Amit Mishra, Megha Maheshwari, Deepak Chhangani, Noriko Fujimori-Tonou, Fumito Endo, Ajay Prakash Joshi, Nihar Ranjan Jana, Koji Yamanaka · 2012 · Neurobiology of Aging
  24. Early gene expression changes in spinal cord from SOD1G93A Amyotrophic Lateral Sclerosis animal model
    G. P. de Oliveira, Chrystian Junqueira Alves, Gerson Chadi · 2013 · Frontiers in Cellular Neuroscience
  25. ALS Patient Stem Cells for Unveiling Disease Signatures of Motoneuron Susceptibility: Perspectives on the Deadly Mitochondria, ER Stress and Calcium Triad
    Anjoscha S. Kaus, Dhruv Sareen · 2015 · Frontiers in Cellular Neuroscience
  26. Assessment of a multiple biomarker panel for diagnosis of amyotrophic lateral sclerosis
    Xueping Chen, Yongping Chen, Qianqian Wei, Ruwei Ou, Bei Cao, Bi Zhao, Huifang Shang · 2016 · BMC Neurology
  27. A Human‐Based Functional NMJ System for Personalized ALS Modeling and Drug Testing
    Xiufang Guo, Virginia Smith, Max Jackson, My Tran, Michael Thomas, Aakash Patel, Eric LoRusso, Siddharth Nimbalkar, Yunqing Cai, Christopher W. McAleer et al. · 2020 · Advanced Therapeutics
  28. How Degeneration of Cells Surrounding Motoneurons Contributes to Amyotrophic Lateral Sclerosis
    Roxane Crabé, Franck Aimond, Philippe Gosset, Frédérique Scamps, Cédric Raoul · 2020 · Cells
  29. Iron accumulation promotes TACE-mediated TNF-α secretion and neurodegeneration in a mouse model of ALS
    Jae Keun Lee, Jin Hee Shin, Byoung Joo Gwag, Eui‐Ju Choi · 2015 · Neurobiology of Disease
  30. Understanding astrocyte differentiation: Clinical relevance, technical challenges, and new opportunities in the omics era
    Michael Lattke, François Guillemot · 2022 · WIREs Mechanisms of Disease
  31. DJ‐1 forms complexes with mutant SOD1 and ameliorates its toxicity
    Satoshi Yamashita, Akira S. Mori, En Kimura, Shuji Mita, Yasushi Maeda, Teruyuki Hirano, Makoto Uchino · 2010 · Journal of Neurochemistry
  32. Recent progress in the discovery of small molecules for the treatment of amyotrophic lateral sclerosis (ALS)
    Allison S. Limpert, Margrith E. Mattmann, Nicholas D. P. Cosford · 2013 · Beilstein Journal of Organic Chemistry
  33. MCP-1/CCR2 signaling-mediated astrocytosis is accelerated in a transgenic mouse model of SOD1-mutated familial ALS
    Motoko Kawaguchi, Tomoko Yamamoto, Yoichiro Kato, Yuri Inose, Noriyuki Shibata · 2013 · Acta Neuropathologica Communications
  34. Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression
    Agnes Badu-Mensah, Xiufang Guo, Christopher W. McAleer, John W. Rumsey, James J. Hickman · 2020 · Scientific Reports
  35. Selective vulnerability of tripartite synapses in amyotrophic lateral sclerosis
    Matthew James Broadhead, Calum Bonthron, Julia Waddington, William V. Smith, Maite F. Lopez, Sarah Burley, Jessica Valli, Fei Zhu, Noboru H. Komiyama, Colin Smith et al. · 2022 · Acta Neuropathologica
  36. Young glial progenitor cells competitively replace aged and diseased human glia in the adult chimeric mouse brain
    Ricardo Vieira, John N. Mariani, Nguyen P.T. Huynh, Hans Jacob Teglbjærg Stephensen, Renee Solly, Ashley Tate, Steven J. Schanz, Natasha Cotrupi, Marzieh Mousaei, Jon Sporring A et al. · 2023 · Nature Biotechnology
  37. Myelin degeneration induced by mutant superoxide dismutase 1 accumulation promotes amyotrophic lateral sclerosis
    Suhyun Kim, Ah‐Young Chung, Ji E. Na, Se Jeong Lee, Sang Hoon Jeong, Eun‐Mi Kim, Woong Sun, Im Joo Rhyu, Hae‐Chul Park · 2019 · Glia
  38. Single-cell transcriptomic and functional studies identify glial state changes and a role for inflammatory RIPK1 signaling in ALS pathogenesis
    Matija Zelic, Anna S. Blazier, Fabrizio Pontarelli, Michael J. LaMorte, Jeremy Huang, Ozge E. Tasdemir-Yilmaz, Yi Ren, Sean K. Ryan, Cynthia Shapiro, Caroline Morel et al. · 2025 · Immunity
  39. Hu Antigen R (HuR) Is a Positive Regulator of the RNA-binding Proteins TDP-43 and FUS/TLS
    Liang Lu, Lei Zheng, Ying Si, Wenyi Luo, Gwendal Dujardin, Thaddaeus Kwan, Nicholas R. Potochick, Sunnie R. Thompson, David Alan Schneider, Peter H. King · 2014 · Journal of Biological Chemistry
  40. Glia–neuron interactions in neurological diseases: Testing non-cell autonomy in a dish
    Kathrin Meyer, Brian K. Kaspar · 2016 · Brain Research
  41. Circuit-Specific Early Impairment of Proprioceptive Sensory Neurons in the SOD1 G93A Mouse Model for ALS
    Soju Seki, Toru Yamamoto, Kiara N. Quinn, Igor Spigelman, Antonios Pantazis, Riccardo Olcese, Martina Wiedau‐Pazos, Scott H. Chandler, Sharmila Venugopal · 2019 · Journal of Neuroscience
  42. Tempol improves neuroinflammation and delays motor dysfunction in a mouse model (SOD1G93A) of ALS
    Gabriela Bortolança Chiarotto, Luciana Politti Cartarozzi, Matheus Perez, Natália P. Biscola, Aline Barroso Spejo, Fernanda Gubert, Marcondes C. França, Rosalia Méndez‐Otero, Alexandre Leite Rodrigues de Oliveira · 2019 · Journal of Neuroinflammation
  43. Altered astrocytic response to activation in SOD1G93A mice and its implications on amyotrophic lateral sclerosis pathogenesis
    Chen Benkler, Tali Ben‐Zur, Yael Barhum, Daniel Offen · 2012 · Glia
  44. Genetic validation of a therapeutic target in a mouse model of ALS
    A. Sophie de Boer, Kathryn Koszka, Evangelos Kiskinis, Naoki Suzuki, Brandi N. Davis‐Dusenbery, Kevin C. Eggan · 2014 · Science Translational Medicine
  45. Emerging Evidence Highlighting the Importance of Redox Dysregulation in the Pathogenesis of Amyotrophic Lateral Sclerosis (ALS)
    Cyril Jones Jagaraj, Sonam Parakh, Julie D. Atkin · 2021 · Frontiers in Cellular Neuroscience
  46. Oxidative and excitotoxic insults exert differential effects on spinal motoneurons and astrocytic glutamate transporters: Implications for the role of astrogliosis in amyotrophic lateral sclerosis
    Chrissandra J. Zagami, Philip M. Beart, Nicole Wallis, Phillip Nagley, Ross D. O’Shea · 2008 · Glia
  47. Advances and challenges in understanding the multifaceted pathogenesis of amyotrophic lateral sclerosis
    Florent Laferrière, Magdalini Polymenidou · 2015 · Swiss Medical Weekly
  48. Dysregulation of Astrocytic HMGB1 Signaling in Amyotrophic Lateral Sclerosis
    Brambilla, Liliana, Martorana, Francesca, Guidotti, Giulia, Rossi, Daniela · 2018 · Frontiers in Neuroscience
  49. Amyotrophic Lateral Sclerosis: Insights and New Prospects in Disease Pathophysiology, Biomarkers and Therapies
    Jameel Mohammed Al-Khayri, Mamtha Ravindran, Akshatha Banadka, Vandana Chendanda Devaiah, Kannu Priya, Praveen Nagella, Kowshik Kukkemane · 2024 · Pharmaceuticals
  50. What Knock-Out Animals Tell Us About the Effects of Caffeine
    Jiang‐Fan Chen, Liqun Yu, Hai‐Ying Shen, Jincai He, Xiaotong Wang, Rong‐Yuan Zheng · 2010 · Journal of Alzheimer s Disease
  51. Severe Neurodegeneration with Impaired Autophagy Mechanism Triggered by Ostm1 Deficiency
    Céline Héraud, Adam Griffiths, Subramanya N. M. Pandruvada, Manfred W. Kilimann, Monica Pata, Jean Vacher · 2014 · Journal of Biological Chemistry
  52. Pathogenic commonalities between spinal muscular atrophy and amyotrophic lateral sclerosis: Converging roads to therapeutic development
    Mélissa Bowerman, Lyndsay M. Murray, Frédérique Scamps, Bernard Laurent Schneider, Rashmi Kothary, Cédric Raoul · 2017 · European Journal of Medical Genetics
  53. Tweak regulates astrogliosis, microgliosis and skeletal muscle atrophy in a mouse model of amyotrophic lateral sclerosis
    Mélissa Bowerman, Céline Salsac, Emmanuelle Coque, E. Eiselt, Roman Goguyer‐Deschaumes, Alexandre Brodovitch, Linda C. Burkly, Frédérique Scamps, Cédric Raoul · 2015 · Human Molecular Genetics
  54. Deleterious effects of lymphocytes at the early stage of neurodegeneration in an animal model of amyotrophic lateral sclerosis
    Satoru Tada, Tatsusada Okuno, Teruhito Yasui, Yuji Nakatsuji, Tomoyuki Sugimoto, Hitoshi Kikutani, Saburo Sakoda · 2011 · Journal of Neuroinflammation
  55. Gut microbiota immune cross-talk in amyotrophic lateral sclerosis
    Megha Kaul, Debanjan Mukherjee, Howard L. Weiner, Laura M. Cox · 2024 · Neurotherapeutics
  56. Purinergic neurone-glia signalling in cognitive-related pathologies
    Péter Illés, Alexei Verkhratsky · 2015 · Neuropharmacology
  57. Unraveling the Complexity of Amyotrophic Lateral Sclerosis: Recent Advances from the Transgenic Mutant SOD1 Mice
    Marco Peviani, Ilaria Caron, Chiara Pizzasegola, Francesco Gensano, Massimo Tortarolo, Caterina Bendotti · 2010 · CNS & Neurological Disorders - Drug Targets
  58. The Role of Neuroinflammation in Neurodegenerative Disorders
    Jessika Suescun, Shivika Chandra, Mya Caryn Schiess · 2018 · Elsevier eBooks
  59. New insights into Wnt signaling alterations in amyotrophic lateral sclerosis: a potential therapeutic target?
    Carlos González‐Fernández, Pau González, Francisco Javier Rodríguez · 2020 · Neural Regeneration Research
  60. Genome Editing for CNS Disorders
    Fábio Teixeira Duarte, Nicole Déglon · 2020 · Frontiers in Neuroscience
  61. Defective Oligodendroglial Lineage and Demyelination in Amyotrophic Lateral Sclerosis
    Élisabeth Traiffort, Séverine Morisset‐Lopez, Mireille Moussaed, Amina Zahaf · 2021 · International Journal of Molecular Sciences
  62. Neuronal over‐expression of chromogranin A accelerates disease onset in a mouse model of ALS
    Samer Abou Ezzi, Roxanne Larivière, Makoto Urushitani, Jean‐Pierre Julien · 2010 · Journal of Neurochemistry
  63. Deregulated expression of cytoskeleton related genes in the spinal cord and sciatic nerve of presymptomatic SOD1G93A Amyotrophic Lateral Sclerosis mouse model
    Jéssica Ruivo Maximino, G. P. de Oliveira, Chrystian Junqueira Alves, Gerson Chadi · 2014 · Frontiers in Cellular Neuroscience
  64. BAFF Controls Neural Cell Survival through BAFF Receptor
    Satoru Tada, Teruhito Yasui, Yuji Nakatsuji, Tatsusada Okuno, Toru Koda, Hideki Mochizuki, Saburo Sakoda, Hitoshi Kikutani · 2013 · PLoS ONE
  65. Review: Evidence-based drug treatment in amyotrophic lateral sclerosis and upcoming clinical trials
    Albert Christian Ludolph, Sarah Jesse · 2009 · Therapeutic Advances in Neurological Disorders
  66. Significance of aberrant glial cell phenotypes in pathophysiology of amyotrophic lateral sclerosis
    Emiliano Trías, Sofía Ibarburu, Romina Barreto‐Núñez, Luis Barbeito · 2016 · Neuroscience Letters
  67. A copper-deficient form of mutant Cu/Zn-superoxide dismutase as an early pathological species in amyotrophic lateral sclerosis
    Eiichi Tokuda, Takao Nomura, Shinji Ohara, Seiji Watanabe, Koji Yamanaka, Yuta Morisaki, Hidemi Misawa, Yoshiaki Furukawa · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  68. The role of immune-mediated alterations and disorders in ALS disease
    Rodrigues Lima-Junior, João, Sulzer, David, Lindestam Arlehamn, Cecilia S., Sette, Alessandro · 2021 · Human Immunology
  69. Selective knockdown of mutant SOD1 in Schwann cells ameliorates disease in G85R mutant SOD1 transgenic mice
    Lijun Wang, Peter Pytel, M. Laura Feltri, Lawrence G. Wrabetz, Raymond P. Roos · 2012 · Neurobiology of Disease
  70. A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients
    Anne‐Li Lind, Di Wu, Eva Freyhult, Constantin Bodolea, Titti Ekegren, Anders Olof Larsson, Mats G. Gustafsson, Lenka Katila, Jonas Bergquist, Torsten Gordh et al. · 2016 · PLoS ONE
  71. Morpholino-mediated SOD1 reduction ameliorates an amyotrophic lateral sclerosis disease phenotype
    Monica Nizzardo, C. Simoné, Federica Rizzo, Gianna Ulzi, Agnese Ramirez, Mafalda Rizzuti, Andreina Bordoni, Monica Bucchia, Stefano Gatti, Nereo Bresolin et al. · 2016 · Scientific Reports
  72. Additive amelioration of ALS by co‐targeting independent pathogenic mechanisms
    Ashley E. Frakes, Lyndsey Braun, Laura Ferraiuolo, Denis C. Guttridge D, Brian K. Kaspar · 2017 · Annals of Clinical and Translational Neurology
  73. Intranasal cotinine improves memory, and reduces depressive-like behavior, and GFAP + cells loss induced by restraint stress in mice
    Nelson Perez-Urrutia, Cristhian Mendoza, Nathalie Alvarez-Ricartes, Patricia Oliveros-Matus, Florencia Echeverria, J. Alex Grizzell, George Emilio Barreto, Alexandre Iarkov, Valentina Echeverrı́a · 2017 · Experimental Neurology
  74. Astrocytic dysfunction induced by ABCA1 deficiency causes optic neuropathy
    Youichi Shinozaki, Alex Leung, Kazuhiko Namekata, Sei Saitoh, Huy Bang Nguyen, Akiko Takeda, Yosuke Danjo, Yosuke M. Morizawa, Eiji Shigetomi, Fumikazu Sano et al. · 2022 · Science Advances
  75. Human stem cell-derived astrocytes and their application to studying Nrf2-mediated neuroprotective pathways and therapeutics in neurodegeneration
    Kunal Gupta, S. Chandran, G. Hardingham · 2012 · British Journal of Clinical Pharmacology
  76. Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells
    Zhong, Zhihui, Ilieva, Hristelina, Hallagan, Lee, Bell, Robert, Singh, Itender, Paquette, Nicole, Thiyagarajan, Meenakshisundaram, Deane, Rashid, Fernandez, Jose A., Lane, Steven et al. · 2009 · Journal of Clinical Investigation
  77. Generation of GFAP::GFP astrocyte reporter lines from human adult fibroblast‐derived i PS cells using zinc‐finger nuclease technology
    Ping-Wu Zhang, Amanda M. Haidet-Phillips, Jacqueline T. Pham, Youngjin Lee, Yuqing Huo, Pentti J. Tienari, Nicholas John Maragakis, Rita Sattler, Jeffrey D. Rothstein · 2015 · Glia
  78. Telomere shortening leads to earlier age of onset in ALS mice
    Birgit Linkus, Diana Wiesner, Martina Meßner, Alexander Karabatsiakis, Annika Scheffold, K. Lenhard Rudolph, Dietmar Rudolf Thal, Jochen Hans Weishaupt, Albert Christian Ludolph, Karin M. Danzer · 2016 · Aging
  79. Testing the diagnostic accuracy of [18F]FDG-PET in discriminating spinal- and bulbar-onset amyotrophic lateral sclerosis
    Arianna Sala, Leonardo Iaccarino, Piercarlo Fania, Emilia Giovanna Vanoli, Federico Fallanca, Caterina Pagnini, Chiara Cerami, Andrea Calvo, Antonio Canosa, Marco Pagani et al. · 2019 · European Journal of Nuclear Medicine and Molecular Imaging
  80. Systemic Dental Pulp Stem Cell Secretome Therapy in a Mouse Model of Amyotrophic Lateral Sclerosis
    Wang Jun-mei, Kirstin Zuzzio, Chandler L. Walker · 2019 · Brain Sciences
  81. Circuit Mechanisms of Neurodegenerative Diseases: A New Frontier With Miniature Fluorescence Microscopy
    Craig T. Werner, Christopher J. Williams, Mercedes R. Fermelia, Da‐Ting Lin, Yun Li · 2019 · Frontiers in Neuroscience
  82. The far-reaching HAND of cART: cART effects on astrocytes
    Hemil Gonzalez, Anthony T. Podany, Lena Al‐Harthi, Jennillee Wallace · 2020 · Journal of Neuroimmune Pharmacology
  83. The Human G93A-Superoxide Dismutase-1 Mutation, Mitochondrial Glutathione and Apoptotic Cell Death
    Håkan Muyderman, P. G. Hutson, Dusan Matusica, Mary‐Louise Rogers, Robert Archer Rush · 2009 · Neurochemical Research
  84. Metalloproteinase alterations in the bone marrow of ALS patients
    Patrizia Bossolasco, Lidia Cova, Cinzia Calzarossa, Federica Servida, Niccolò Emanuele Mencacci, Francesco Onida, Elio E Polli, Giorgio Lambertenghi Deliliers, Vincenzo Silani · 2010 · Journal of Molecular Medicine
  85. Pathobiology of Neurodegeneration: The Role for Astroglia
    Alexei Verkhratsky, Robert Zorec, Jose Julio Rodriguez, Vladimir Parpura · 2016 · PubMed
  86. Astrocyte-derived Jagged-1 mitigates deleterious Notch signaling in amyotrophic lateral sclerosis
    Annelies Nonneman, Nathan Criem, Sebastian A. Lewandowski, Rik Nuyts, Dietmar Rudolf Thal, Frank W. Pfrieger, John Ravits, Philip Van Damme, An Zwijsen, Ludo Van Den Bosch et al. · 2018 · Neurobiology of Disease
  87. Thrombin and the Coag-Inflammatory Nexus in Neurotrauma, ALS, and Other Neurodegenerative Disorders
    Barry W. Festoff, Bruce A. Citron · 2019 · Frontiers in Neurology
  88. Reactive astrocytes in ALS display diminished intron retention
    Oliver Jonathan Ziff, Doaa M Taha, Hamish Crerar, Benjamin E. Clarke, Anob M. Chakrabarti, Gavin P. Kelly, Jacob Neeves, Giulia E. Tyzack, Nicholas M. Luscombe, Rickie Patani · 2021 · Nucleic Acids Research
  89. Neuroprotective Function of Cellular Prion Protein in a Mouse Model of Amyotrophic Lateral Sclerosis
    Petra Steinacker, Andreas E. Hawlik, Stefan Lehnert, Olaf Jahn, Stephen Meier, Evamaria Görz, Kerstin E. Braunstein, Marija Krzovska, Birgit Schwalenstöcker, Sarah Jesse et al. · 2010 · American Journal Of Pathology
  90. A cysteine residue affects the conformational state and neuronal toxicity of mutant SOD1 in mice: relevance to the pathogenesis of ALS
    Seiichi Nagano, Y. Takahashi, Kazuhiro Yamamoto, Hiroshi Masutani, Noriko Fujiwara, Makoto Urushitani, Toshiyuki Araki · 2015 · Human Molecular Genetics
  91. Electrophilic nitro-fatty acids prevent astrocyte-mediated toxicity to motor neurons in a cell model of familial amyotrophic lateral sclerosis via nuclear factor erythroid 2-related factor activation
    Pablo Díaz‐Amarilla, Ernesto Miquel, Andrés Trostchansky, Emiliano Trías, Ana Maria Ferreira, Bruce Α. Freeman, Patricia Cassina, Luis Barbeito, Marcelo R. Vargas, Homero Rubbo · 2016 · Free Radical Biology and Medicine
  92. Dissociation of blood-brain barrier disruption and disease manifestation in an aquaporin-4-deficient mouse model of amyotrophic lateral sclerosis
    Saori Watanabe-Matsumoto, Yasuhiro Moriwaki, Takashi Okuda, Shinji Ohara, Koji Yamanaka, Yoichiro Abe, Masato Yasui, Hidemi Misawa · 2017 · Neuroscience Research
  93. Status of ALS treatment, insights into therapeutic challenges and dilemmas
    Khamaysa, Mohammed, Pradat, Pierre-François · 2022 · Journal of Personalized Medicine
  94. Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2-Aminopyridine-Based Scaffold with a Pyridine Linker
    Heng‐Yen Wang, Yajuan Qin, Huiying Li, Linda J. Roman, Pavel Martasek E, T.L. Poulos, Richard B. Silverman · 2016 · Journal of Medicinal Chemistry
  95. Astrocytes As the Main Players in Primary Degenerative Disorders of the Human Central Nervous System
    Francisco Capani, Cecilia Quarracino, Roberto L. Caccuri, Roberto E.P. Sica · 2016 · Frontiers in Aging Neuroscience
  96. Phase 2 randomized placebo controlled double blind study to assess the efficacy and safety of tecfidera in patients with amyotrophic lateral sclerosis (TEALS Study)
    Steve Vucic, Julie Ryder, Linda Mekhael, Henderson RD, Susan Mathers, Merrilee Needham, David W Schultz, Matthew C. Kiernan · 2020 · Medicine
  97. Implication of HMGB1 signaling pathways in Amyotrophic lateral sclerosis (ALS): From molecular mechanisms to pre-clinical results
    Yam Nath Paudel, Efthalia Angelopoulou, Christina Piperi, Iekhsan Othman, Mohd. Farooq Shaikh · 2020 · Pharmacological Research
  98. Necroptosis in CNS diseases: Focus on astrocytes
    Еlena V. Mitroshina, Mariia O. Saviuk, Maria V. Vedunova · 2023 · Frontiers in Aging Neuroscience
  99. Astrocytes: Dissecting Their Diverse Roles in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
    Chiara F. Valori, Claudia Sulmona, Liliana Brambilla, Daniela Rossi · 2023 · Cells
  100. Polyglutamine toxicity in non-neuronal cells
    Jennifer W. Bradford, Shihua Li, Xiao‐Jiang Li · 2010 · Cell Research