Cited by 652Schizophrenia research and treatmentNeurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

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Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia

Meyer-Lindenberg, Andreas, Miletich, Robert S., Kohn, Philip D., Esposito, Giuseppe, Carson, Richard E., Quarantelli, Mario, Weinberger, Daniel R., Berman, Karen Faith·2002·Nature Neuroscience

DOI 10.1038/nn804

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Abstract

Both dopaminergic neurotransmission and prefrontal cortex (PFC) function are known to be abnormal in schizophrenia. To test the hypothesis that these phenomena are related, we measured presynaptic dopaminergic function simultaneously with regional cerebral blood flow during the Wisconsin Card Sorting Test (WCST) and a control task in unmedicated schizophrenic subjects and matched controls. We show that the dopaminergic uptake constant Ki in the striatum was significantly higher for patients than for controls. Patients had significantly less WCST-related activation in PFC. The two parameters were strongly linked in patients, but not controls. The tight within-patient coupling of these values, with decreased PFC activation predicting exaggerated striatal 6-fluorodopa uptake, supports the hypothesis that prefrontal cortex dysfunction may lead to dopaminergic transmission abnormalities.

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Co-Planar Stereotaxic Atlas of the Human Brain
Talairach, J., & Tournoux, P. (1988) · Medical Entomology and Zoology · Cited by 11,798
Co-planar stereotaxic atlas of the human brain
Laitinen, L. (1989) · Clinical Neurology and Neurosurgery · doi:10.1016/0303-8467(89)90128-5 · Cited by 7,565
Implications of Normal Brain Development for the Pathogenesis of Schizophrenia
Weinberger, D. R. (1987) · Archives of General Psychiatry · doi:10.1001/archpsyc.1987.01800190080012 · Cited by 3,724
Self-citation
Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data
Patlak, C. S., Blasberg, R. G., & Fenstermacher, J. D. (1983) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1983.1 · Cited by 3,565
Dementia Praecox and Paraphrenia.
(1972) · Annals of Internal Medicine · doi:10.7326/0003-4819-76-6-1058_8 · Cited by 2,907
Physiologic Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia
Weinberger, D. R. (1986) · Archives of General Psychiatry · doi:10.1001/archpsyc.1986.01800020020004 · Cited by 2,025
Self-citation
Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: A hypothesis for the etiology of schizophrenia
Grace, A. A. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90196-u · Cited by 1,831
MRI-PET Registration with Automated Algorithm
Woods, R. P., Mazziotta, J. C., & Cherry, A. S. R. (1993) · Journal of Computer Assisted Tomography · doi:10.1097/00004728-199307000-00004 · Cited by 1,636
Positron-emission tomography
Ollinger, J. M., & Fessler, J. A. (1997) · IEEE Signal Processing Magazine · doi:10.1109/79.560323 · Cited by 1,168
Increased baseline occupancy of D 2 receptors by dopamine in schizophrenia
Abi-Dargham, A., Rodenhiser, J., Printz, D., Zea-Ponce, Y., Gil, R., Kegeles, L. S., Weiss, R., Cooper, T. B., Mann, J. J., Van Heertum, R. L., et al. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.14.8104 · Cited by 1,020

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Kraepelin, E., Barclay, R. M. & Robertson, G. M. Dementia Præcox and Paraphrenia (E. & S. Livingstone, Edinburgh, 1919).

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Items 501–600 of 646

A New BODIPY-Based Receptor for the Fluorescent Sensing of Catecholamines
Puglisi, R., Cavallaro, A., Pappalardo, A., Petroselli, M., Santonocito, R., & Sfrazzetto, G. T. (2024) · Molecules · doi:10.3390/molecules29153714 · Cited by 5
Neural Injury of the Dopaminergic Pathways in Patients with Middle Cerebral Artery Territory Infarct: A Diffusion Tensor Imaging Study
Seo, J. P., & Ryu, H.-J. (2023) · Brain Sciences · doi:10.3390/brainsci13060927 · Cited by 5
Increased Striatal Presynaptic Dopamine in a Nonhuman Primate Model of Maternal Immune Activation: A Longitudinal Neurodevelopmental Positron Emission Tomography Study With Implications for Schizophrenia
Smucny, J., Vlasova, R., Lesh, T. A., Rowland, D. J., Wang, G., Chaudhari, A. J., Chen, D., Iosif, A., Hogrefe, C. E., Bennett, J. L., et al. (2022) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2022.10.012 · Cited by 6
Electrophysiological Imaging Evaluation of Schizophrenia and Treatment Response
Sumiyoshi, T., Higuchi, Y., Ito, T., & Kawasaki, Y. (2011) · Springer eBooks · doi:10.1007/978-94-007-0834-1_7 · Cited by 5
Preserved Intention Maintenance and Impaired Execution of Prospective Memory Responses in Schizophrenia: Evidence from an Event-based Prospective Memory Study
Demeter, G., Szendi, I., Domján, N., Juhász, M., Greminger, N., Szöllősi, Á., & Racsmány, M. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.00593 · Cited by 5
WISCONSIN CARD SORTING TEST FOR THE STUDY OF ATTENTION DEFICIT WITH HYPERACTIVITY, PSYCHIATRIC DISORDERS, AUTISM AND AGING
Angrino, S. O., & Panesso, I. C. (2007) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) · Cited by 5
Modulation of dopamine D2 receptors as a basis of antipsychotic effect
(2003) · CRC Press eBooks · doi:10.3109/9780203427347-4 · Cited by 5
Pharmacotherapy of Schizophrenia
Sharif, Z. A., Miyamoto, S., & Lieberman, J. A. (2007) · Wiley eBooks · doi:10.1002/9780470101001.hcn033 · Cited by 5
Long-term adaptation of prefrontal circuits in a mouse model of NMDAR hypofunction
Ponserre, M., Ionescu, T. M., Franz, A. A., Deiana, S., Schuelert, N., Lamla, T., Williams, R. H., Wotjak, C. T., Hobson, S., Dine, J., et al. (2024) · Neuropharmacology · doi:10.1016/j.neuropharm.2024.109970 · Cited by 4
Glutamate Pharmacological Models Relevant to Schizophrenia and Psychosis
Rafter, M. D., Fone, K. C. F., & Moran, P. M. (2015) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-12-800981-9.00010-9 · Cited by 4
Paradoxical effects of drugs on cognitive function: the neuropsychopharmacology of the dopamine and other neurotransmitter systems
Cools, R., Aarts, E., & Mehta, M. A. (2011) · Cambridge University Press eBooks · doi:10.1017/cbo9780511978098.025 · Cited by 4
Through a Glass Darkly: Schizophrenia and Functional Brain Imaging
Lloyd, D. E. (2011) · Philosophy, psychiatry & psychology · doi:10.1353/ppp.2011.0046 · Cited by 4
Gene–Environment Interactions for Searchers: Collaboration between Epidemiology and Molecular Genetics
van Os, J., Rutten, B. P. F., & Poulton, R. (2009) · Springer eBooks · doi:10.1007/978-1-4419-0913-8_2 · Cited by 4
Identification of rare high-risk copy number variants affecting the dopamine transporter gene in mental disorders
Hoeffding, L. K., Duong, L. T. T., Ingason, A., Rosengren, A., Sorbanski, E., Witt, S. H., Djurovic, S., Andreassen, O. A., Hansen, T. F., Werge, T. M., et al. (2015) · Nordic Journal of Psychiatry · doi:10.3109/08039488.2015.1095944 · Cited by 4
Association between schizophrenia risk allele dosage of rs6994992 and whole-brain structural and functional characteristics
Zhang, W., Cai, S., Huang, K., Lv, Y., Kang, Y., Wang, Q., & Huang, L. (2019) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2019.05.005 · Cited by 5
Modeling Psychiatric Disorders in Experimental Animals
Moore, H. M., & Robbins, T. W. (2015) · Wiley eBooks · doi:10.1002/9781118753378.ch17 · Cited by 4
Investigating changes in the premotor cortex-derived frontal-striatal-thalamic subcircuit in attenuated psychosis syndrome
Katagiri, N., Tagata, H., Uchino, T., Arai, Y., Saito, J., Kamiya, K., Hori, M., Mizuno, M., & Nemoto, T. (2024) · Brain Imaging and Behavior · doi:10.1007/s11682-024-00906-6 · Cited by 3
Oxidase-like Ce(IV)-ATP-Tris coordination polymer nanoparticles for peroxide-free colorimetric detection of catecholamines
Kadlag, S. S., Ghosh, M., Pathak, A., Dey, M. K., Ghosh, A., Singh, P. K., & Swain, K. K. (2025) · Microchemical Journal · doi:10.1016/j.microc.2025.116335 · Cited by 3
Functional ultrasound imaging and prewhitening analysis reveal MK-801-induced disruption of brain network connectivity
Hakopian, E., Stepanian, A. E., Zhong, S., Agyeman, K. A., Zepeda, N., Wu, K., Liu, C. Y., Lee, D. J., & Christopoulos, V. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1562102 · Cited by 3
Rethinking the Contribution of Neuroimaging to Translation in Schizophrenia
Tost, H., Zangl, M., & Meyer‐Lindenberg, A. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-386945-6.00006-8 · Cited by 3
Self-citation
Effect of substituents on 3(S)-amino-1-hydroxy-3,4-dihydroquinolin-2(1H)-one: a DFT study
Lira, J., Valencia, D. E., Barazorda-Ccahuana, H. L., Cárdenas-Garcia, J., & Gómez, B. (2019) · Theoretical Chemistry Accounts · doi:10.1007/s00214-018-2403-0 · Cited by 3
Computational model predicts the neural mechanisms of prepulse inhibition in Drosophila larvae
Furuya, K., Katsumata, Y., Ishibashi, M., Matsumoto, Y., Morimoto, T., & Aonishi, T. (2022) · Scientific Reports · doi:10.1038/s41598-022-19210-8 · Cited by 3
MicroRNA dysregulation in glutamate and dopamine pathways of schizophrenia: From molecular pathways to diagnostic and therapeutic approaches
Khosroshahi, P. A., & Ghanbari, M. (2024) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2024.111081 · Cited by 4
Pharmakotherapie kognitiver Störungen
Gründer, G. (2007) · Springer eBooks · doi:10.1007/978-3-540-71147-6_48 · Cited by 3
Functional neuro-imaging in schizophrenia
Nosarti, C., & Shergill, S. S. (2008) · Psychiatry · doi:10.1016/j.mppsy.2008.07.017 · Cited by 3
EPIGENETIC AND GENETIC ABERRATIONS OF THE BRAIN DOPAMINERGIC SYSTEM IN SCHIZOPHRENIA AND BIPOLAR DISORDER: ACHIEVEMENTS AND PROSPECTIVE
Abdolmaleky, H. M., Ahmadkhaniha, H., Nohesara, S., & Smith, C. L. (2008) · Iranian Journal of Psychiatry and Behavioral Sciences · Cited by 3
Exploring the relation between BOLD fMRI and cognitive performance using a computer-based quantitative systems pharmacology model: Applications to the COMTVAL158MET genotype and ketamine
Geerts, H., Roberts, P., & Spiros, Ä. (2021) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2021.04.001 · Cited by 3
Errors in Text in: Suicide Risk in Primary Care Patients With Major Physical Diseases: A Case-Control Study
(2012) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2012.630 · Cited by 3
Evidence from brain imaging studies for dopaminergic alterations in schizophrenia
Abi‐Dargham, A. (2003) · CRC Press eBooks · doi:10.3109/9780203427347-3 · Cited by 3
Dopamine Receptor Imaging in Schizophrenia
Hirvonen, J., & Hietala, J. A. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-418677-4.00013-0 · Cited by 3
The Biology of Schizotaxia
Stone, W. S., Glatt, S. J., & Faraone, S. V. (2004) · Humana Press eBooks · doi:10.1007/978-1-59259-729-1_16 · Cited by 3
Dopamine and Glutamate Hypotheses of Schizophrenia
Moghaddam, B., & Homayoun, H. (2007) · Wiley eBooks · doi:10.1002/9780470101001.hcn030 · Cited by 3
High levels of impulsivity in rats are not accompanied by sensorimotor gating deficits and locomotor hyperactivity
Feja, M., Lang, M., Deppermann, L., Yüksel, A. E., & Wischhof, L. (2015) · Behavioural Processes · doi:10.1016/j.beproc.2015.10.011 · Cited by 2
From risk to chronicity: genetic and neuroimaging insights into the evolving patterns of spontaneous brain activity in schizophrenia
Zhang, Y., Wang, H., Cai, M., Wang, W., Qiao, J., Wang, X., Wu, Y., Wu, Q., Zhang, Z., Lei, M., et al. (2025) · Psychological Medicine · doi:10.1017/s0033291725102006 · Cited by 2
Applications of Clinical Dopamine Imaging
Lindsey, K. P., & Gatley, S. J. (2007) · PET Clinics · doi:10.1016/j.cpet.2007.09.005 · Cited by 2
Şizofrenide Kombinasyon Tedavileri
Altınyazar, V., & Yüksel, N. (2011) · Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology · doi:10.5455/bcp.20110701011007 · Cited by 2
Hallucinations, conscience et psychoses
Cul, A. D., Gaillard, R., Jardri, R., & Fossati, P. (2010) · L Encéphale · doi:10.1016/j.encep.2010.07.001 · Cited by 3
Stable and Unstable Activation of the Prefrontal Cortex with Dopaminergic Modulation
Tanaka, S. (2007) · Springer eBooks · doi:10.1007/978-0-387-72256-6_16 · Cited by 2
10.4 Dopamine Dysfunction in Schizophrenia: From Genetic Susceptibility to Cognitive Impairment
Tost, H., Hakimi, S., & Meyer‐Lindenberg, A. (2009) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780195373035.003.0039 · Cited by 2
Self-citation
Dopamine and Response to Antipsychotic Medication
Ntephe, C., & Demjaha, A. (2020) · Springer eBooks · doi:10.1007/978-3-030-57231-0_14 · Cited by 2
Four-modality imaging of unmedicated subjects with schizophrenia: 18F-fluorodeoxyglucose and 18F-fallypride PET, diffusion tensor imaging, and MRI
Buchsbaum, M. S., Mitelman, S. A., Christian, B. T., Merrill, B., Buchsbaum, B. R., Mitelman, D., Mukherjee, J., & Lehrer, D. S. (2021) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2021.111428 · Cited by 2
Imaging Genetics: Unraveling the Neurogenetic Risk Architecture of Mental Illness
Tost, H., Böhringer, A., & Meyer‐Lindenberg, A. (2014) · Springer eBooks · doi:10.1007/978-3-642-54542-9_7 · Cited by 2
Self-citation
THE SUBCORTICAL CONFINEMENT HYPOTHESIS: A NEUROLOGICAL MODEL FOR SCHIZOTYPAL HALLUCINATIONS.
Golembiewski, J. A. (2013) · Cureus · doi:10.7759/cureus.118 · Cited by 2
The neuromediator mechanisms of the cognitive deficit in schizophrenia
Storozheva, Z. I., Kirenskaya, A. V., & Proshin, A. T. (2015) · Neurochemical Journal · doi:10.1134/s1819712415030095 · Cited by 2
Evaluierung der Testbatterie zur Aufmerksamkeitsprüfung (TAP) als kognitiver Endophänotyp der Schizophrenie
Kley, F. (2009) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-4758 · Cited by 2
Esquizofrenia y neurodesarrollo
Valencia, J. G., Miranda, A., Jaramillo, C. A. L., Acosta, C. A. P., Franco, J. G., & Duque, J. O. (2005) · Institutional Repository University of Antioquia (University of Antioquia) · Cited by 2
[Diffusion images on brain MRI in Creutzfeldt-Jakob disease].
Nagaoka, U., Kurita, K., Hosoya, T., Kitamoto, T., & Kato, T. (1999) · PubMed · Cited by 2
Toward Predicting Impact of Common Genetic Variants on Schizophrenia Clinical Responses With Antipsychotics: A Quantitative System Pharmacology Study
Spiros, Ä., & Geerts, H. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.738903 · Cited by 1
White matter abnormalities of the frontal–striatal–thalamic circuit in individuals with attenuated positive symptom syndromes: a probabilistic tractography study
Chen, Z., Bo, Q., Zhao, L., Ding, Y., Wang, Y., Jiang, Q., Li, F., Zhou, Y., & Wang, C. (2025) · Schizophrenia · doi:10.1038/s41537-025-00635-9 · Cited by 1
Schizophrenia Beyond Genome-Wide Association Studies: It’s About Time
Pergola, G., & Weinberger, D. R. (2026) · American Journal of Psychiatry · doi:10.1176/appi.ajp.20260566 · Cited by 1
Self-citation
Neurotensin
Dobner, P. R., & Carraway, R. E. (2009) · CRC Press eBooks · doi:10.1201/9781420061161-c10 · Cited by 1
Pharmakotherapie kognitiver Störungen bei Schizophrenie – zwischen Hoffnung und Enttäuschung
Paulzen, M., & Toto, S. (2025) · Der Nervenarzt · doi:10.1007/s00115-025-01846-2 · Cited by 1
Ketamine for negative and depressive symptoms in schizophrenia: the evidence so far
Diendorfer, C., Bum, C., Weidenauer, A., Sauerzopf, U., Bartova, L., Dajic, I., Müller, L., Rujescu, D., Praschak-Rieder, N., & Willeit, M. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1766485 · Cited by 1
Evaluating neurochemical changes and associated locomotor activity in a double hit schizophrenia model
Shangase, K. B., Luvuno, M., & Mabandla, M. V. (2026) · IBRO Neuroscience Reports · doi:10.1016/j.ibneur.2026.03.004 · Cited by 1
18F-fluorodeoxyglucose PET in Major Psychiatric Disorders
Ferrando, R., & Coutinho, A. M. (2026) · PET Clinics · doi:10.1016/j.cpet.2026.05.007 · Cited by 1
fMRI Investigations of the Mesolimbic Dopaminergic Reward System in Schizophrenia
Juckel, G. (2014) · Springer eBooks · doi:10.1007/978-3-642-54542-9_12 · Cited by 1
Hirnelektrische Hypofrontalität bei schizophrenen Patienten und ihre Bedeutung für die Auswahl der neuroleptischen Medikation
Würzburg, J.-M.-U., & Ehlis, A. (2007) · Cited by 1
Frontal lobe
Clark, D. L., Boutros, N. N., & Mendez, M. F. (2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511776915.008 · Cited by 1
Developmental 17-OHPC exposure disrupts behavior regulated by the mesocorticolimbic dopaminergic system in rats
Graney, P. L., Chen, M. Y., Wood, R. I., & Wagner, C. K. (2024) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2024.173886 · Cited by 1
Promising novel drug delivery approaches in the development of therapeutics for schizophrenia disease management
Shareena, G., & Kumar, D. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13474-6.00026-3 · Cited by 1
Dopamine and the Biology and Course of Treatment Resistance
Demjaha, A., & Howes, O. D. (2014) · Springer eBooks · doi:10.1007/978-3-642-45257-4_3 · Cited by 1
¿Media la dopamina los efectos psicóticos del Cannabis? Revisión e integración de los hallazgos a través de disciplinas
Kuepper, R., Morrison, P. D., van Os, J., Murray, R. M., Kenis, G., & Henquet, C. (2012) · Psiquiatría Biológica · doi:10.1016/j.psiq.2012.09.005 · Cited by 1
Neuroimaging Biomarkers in Schizophrenia
Tost, H., & Meyer‐Lindenberg, A. (2008) · Springer eBooks · doi:10.1007/978-0-387-79251-4_11 · Cited by 1
Self-citation
Estimulación magnética transcraneal para síntomas negativos en la esquizofrenia: una revisión
Vásquez, R. M. Z., Saracco-Álvarez, R. A., & Olvera, J. G. (2010) · Hispana · Cited by 1
Effects of Sequential Frontotemporal Repetitive Transcranial Magnetic Stimulation (rTMS) on Schizophrenia
Přikryl, R., Ustohal, L., Kučerová, H. P., Čermáková, I., & Češková, E. (2010) · Cited by 1
Neuroimaging
Steele, J. D., & Lawrie, S. M. (2010) · Elsevier eBooks · doi:10.1016/b978-0-7020-3137-3.00004-8 · Cited by 1
Molecular Imaging
Červenka, S., & Farde, L. (2020) · Springer eBooks · doi:10.1007/978-3-030-35206-6_8 · Cited by 1
10.1 Dopamine Dysfunction in Schizophrenia
Abi‐Dargham, A., Slifstein, M., Kegeles, L., & Laruelle, M. A. (2009) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780195373035.003.0036 · Cited by 1
L’hypothèse dopaminergique revisitée
Guillin, O. (2006) · L Encéphale · doi:10.1016/s0013-7006(06)76262-5 · Cited by 1
In Vivo Imaging of Dopamine Receptors
Abi‐Dargham, A., & Laruelle, M. A. (2009) · The Receptors · doi:10.1007/978-1-60327-333-6_15 · Cited by 1
Untersuchungen zum endogenen Reward-System unter Therapie von atypischen und klassischen Antipsychotika
Juckel, G., Schlagenhauf, F., & Heinz, A. (2010) · Springer eBooks · doi:10.1007/978-3-211-92215-6_11 · Cited by 1
Decision-Making, Behavioral Supervision and Learning: An Executive Role for the Ventral Premotor Cortex?
Acuña, C., Pardo‐Vázquez, J. L., & Leborán, V. (2010) · Springer eBooks · doi:10.1007/978-1-4614-0785-0_23 · Cited by 1
Cerebello-Basal Ganglia Functional Network Integration in PsychosisPreprint
Jackson, T. B., Damme, K. S. F., Mittal, V. A., & Bernard, J. A. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.11.12.516285 · Cited by 1
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Goulding, S. R. (2021) · doi:10.34719/fhhg1227 · Cited by 1
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Tubiolo, P. N., Williams, J. C., Gil, R. B., Cassidy, C., Haubold, N. K., Patel, Y., Abeykoon, S. K., Zheng, Z. J., Pham, D. T., Ojeil, N., et al. (2025) · medRxiv · doi:10.1101/2025.03.31.25324962 · Cited by 1
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Peeters, S. C. T. (2015) · doi:10.26481/dis.20150624sp
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Willeit, M., Kasper, S. F., & Praschak-Rieder, N. (2014) · Springer eBooks · doi:10.1007/978-3-642-42014-6_6
A dynamic model of the onset of clinical psychosis from an epidemiological perspective
Barrera, M. D. G. D. (2009) · Research Publications (Maastricht University) · doi:10.26481/dis.20091217md
Onset, course and comorbidity of bipolar symptoms in population and treatment settings
Rossum, I. W.-V. (2010) · Research Publications (Maastricht University) · doi:10.26481/dis.20100114ir
Systematic Analysis of disease pathways in Congenital, Infantile and Juvenile Neuronal Ceroid Lipofuscinoses
Scifo, E. (2014) · Työväentutkimus Vuosikirja
A study of conditioned inhibition procedures in relation to individual differences and disorder
He, Z. (2011) · Nottingham ePrints (University of Nottingham)
Epidemiological and biological mechanisms of cannabis as cause of psychosis
Kuepper, R. (2012) · Research Publications (Maastricht University) · doi:10.26481/dis.20120504rk
Progress in Psychopharmacotherapy though Molecular Imaging
Vernaleken, I., Gruender, G., & Cumming, P. D. (2010) · Wiley eBooks · doi:10.1002/9783527630271.ch9
FGF signaling in neurogenesis and patterning of the developing midbrain and anterior hindbrain
Lahti, L. (2012) · Työväentutkimus Vuosikirja
The prefrontal cortex and information processing : nitric oxide signaling studied in an animal model of schizophrenia
Fejgin, K. (2008) · Gothenburg University Publications Electronic Archive (Gothenburg University)
Proposition d’un modèle animal de psychose schizophréniforme sur la base des troubles de la neurotransmission et du comportement spontané du rat soumis aux hautes pressions
Fechtali, T., & Abraini, J. H. (2011) · PRSM · doi:10.34874/prsm.teclab-vol2iss5.335
Characterization of the D-amino acid oxidase interactome
Popiolek, M. (2010) · UCL Discovery (University College London)
Störungen der Selbst-Fremd-Differenzierung willkürlicher Handlungen bei psychosegefährdeten Patienten und Patienten mit Schizophrenie im Vergleich zu gesunden Probanden
Hauser, M. (2011) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-15371
Characterization of dopamine D1 receptor agonists in vivo- Implications for the treatment of schizophrenia and Parkinson s disease
Isacson, R. (2008) · Figshare
Les systèmes de neurotransmission centraux et leur implication dans les psychoses
Martres, M. (2008) · Therapies · doi:10.2515/therapie:2008030
Investigation of neuronal structures and networks on the modulation of decision-making and impulse control by temporary inactivation via local microinfusion of the GABAA receptor agonist muscimol in rats
Feja, M. (2014)
Modafinil for schizophrenia
Scoriels, L., Barnett, J. H., & Jones, P. B. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008661
Bildgebende Verfahren bei psychischen Störungen
Braus, D. F., Tost, H., & Demirakça, T. (2010) · Springer eBooks · doi:10.1007/978-3-540-72340-0_6
Do All Individuals with Schizophrenia Have Cluttering
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Neto, A. F. R. (2016) · TDX (Tesis Doctorals en Xarxa)
Molecular Imaging in Schizophrenia
Howes, O. D. (2012) · Neuromethods · doi:10.1007/7657_2012_57

Authors: Meyer-Lindenberg, A., Miletich, R. S., Kohn, P. D., Esposito, G., Carson, R. E., Quarantelli, M., Weinberger, D. R., & Berman, K. F.
Affiliations: National Institutes of Health (US)
ORCID: Carson, Richard E.
Quarantelli, Mario
Weinberger, Daniel R.
Berman, Karen Faith
Venue: Nature Neuroscience
Publisher: Springer Science and Business Media LLC
Published: 2002-01-28
Volume: 5
Issue: 3
Pages: 267-271
ISSN: 1097-6256 (ISSN-L)
1546-1726
DOI: 10.1038/nn804
OpenAlex: W2004729128
Cited by: 652
References: 50
Citations by year: 2026: 8 · 2025: 14 · 2024: 13 · 2023: 9 · 2022: 15 · 2021: 30 · 2020: 16 · 2019: 32 · 2018: 20 · 2017: 25 · 2016: 31 · 2015: 41 · 2014: 35 · 2013: 38 · 2012: 40
FWCI: 19.67
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Nature Neuroscience (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Keywords: schizophrenia, prefrontal cortex, striatum, dopamine signaling, dopamine uptake, regional cerebral blood flow, Wisconsin Card Sorting Test, prefrontal cortex activation
MeSH terms: Cerebrovascular Circulation, Corpus Striatum, Dihydroxyphenylalanine, Dopamine, Fluorine Radioisotopes, Humans, Neuropsychological Tests, Schizophrenia, Statistics as Topic, Synapses, Tomography, Emission-Computed, Prefrontal Cortex

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Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia

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