The DOI matches its Crossref record; 153 of the 153 references it cites were found in a registry or an index.
Challenges and opportunities for structural DNA nanotechnology
Open accessAbstract
DNA molecules have been used to build a variety of nanoscale structures and devices over the past 30 years, and potential applications have begun to emerge. But the development of more advanced structures and applications will require a number of issues to be addressed, the most significant of which are the high cost of DNA and the high error rate of self-assembly. Here we examine the technical challenges in the field of structural DNA nanotechnology and outline some of the promising applications that could be developed if these hurdles can be overcome. In particular, we highlight the potential use of DNA nanostructures in molecular and cellular biophysics, as biomimetic systems, in energy transfer and photonics, and in diagnostics and therapeutics for human health.
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“The growing field of DNA (and RNA) origami provides many examples of compartments assembled from nucleic acids (for reviews, see Pinheiro et al. 2011;Hong et al. 2017).”
From Protocells and RNA Self-Replication (2018) · cites this paper as Pinheiro et al. 2011
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“DNA nanotechnology leverages the unparalleled molecular recognition motifs of the nitrogenous bases to create arbitrary two- and three-dimensional structures from the self-assembly of user-defined DNA strands.”
From Emerging Approaches to DNA Data Storage: Challenges and Prospects (2022) · cites this paper as [103]
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Cites
1 retracted
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Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations
Jeevanandam, J., Barhoum, A., Chan, Y. S., Dufresne, A., & Danquah, M. K. (2018) · Beilstein Journal of Nanotechnology · doi:10.3762/bjnano.9.98 · Cited by 3,362
Self-Assembly of Colloidal Nanocrystals: From Intricate Structures to Functional Materials
Boles, M. A., Engel, M., & Talapin, D. V. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00196 · Cited by 2,095
The History of Nanoscience and Nanotechnology: From Chemical–Physical Applications to Nanomedicine
Bayda, S., Adeel, M., Tuccinardi, T., Cordani, M., & Rizzolio, F. (2019) · Molecules · doi:10.3390/molecules25010112 · Cited by 2,098
Isothermal Amplification of Nucleic Acids
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A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo
Li, S., Jiang, Q., Liu, S., Zhang, Y., Tian, Y., Song, C., Wang, J., Zou, Y., Anderson, G. J., Han, J.-Y., et al. (2018) · Nature Biotechnology · doi:10.1038/nbt.4071 · Cited by 1,481
Self-citation
Metadata
- Authors
- Pinheiro, A. V., Han, D., Shih, W. M., & Yan, H.
- Affiliations
- Arizona State University (US)
- Harvard University (US)
- Corresponding author
- Shih, William M.
- Yan, Hao
- Venue
- Nature Nanotechnology
- Published
- 2011-11-06
- Volume
- 6
- Issue
- 12
- Pages
- 763-772
- ISSN
- 1748-3387 (ISSN-L)
- 1748-3395
- PMC
- PMC3334823
- OpenAlex
- W2077850544
- Cited by
- 1,292
- References
- 153
- Citations by year
- 2026: 35 · 2025: 46 · 2024: 50 · 2023: 65 · 2022: 70 · 2021: 84 · 2020: 82 · 2019: 96 · 2018: 118 · 2017: 122 · 2016: 112 · 2015: 110 · 2014: 110 · 2013: 134 · 2012: 57
- FWCI
- 8.74
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Nanotechnology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- U.S. Department of Energy (DESC0001016)
- Arizona State University
- Hansjörg Wyss Institute for Biologically Inspired Engineering, Harvard University
- Office of Naval Research
- National Institute of General Medical Sciences (R01GM088818)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Advanced biosensing and bioanalysis techniques
- Physical Sciences › Mathematics › Theoretical Computer Science › DNA and Biological Computing
- Physical Sciences › Materials Science › Biomaterials › Supramolecular Self-Assembly in Materials
- Keywords
- DNA nanotechnology, DNA nanostructures, molecular biophysics, cellular biophysics, biomimetic systems, energy transfer, photonics, diagnostics, therapeutics
- MeSH terms
- DNA, Humans, Nucleic Acid Conformation, Nanotechnology, Biomimetic Materials, Nanostructures
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