Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner

Chauhan, Vikash P., Stylianopoulos, Triantafyllos, Martin, John D., Popović, Zoran, Chen, Ou, Kamoun, Walid S., Bawendi, Moungi G., Fukumura, Dai +1 more·2012·Nature Nanotechnology

DOI 10.1038/nnano.2012.45

Cited by (1,000)

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Siegel, Ronald A., Kirtane, Ameya R., Panyam, Jayanth · 2017 · IEEE Transactions on Biomedical Engineering
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