Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner

Chauhan, Vikash P., Stylianopoulos, Triantafyllos, Martin, John D., Popović, Zoran, Chen, Ou, Kamoun, Walid S., Bawendi, Moungi G., Fukumura, Dai +1 more·2012·Nature Nanotechnology

Cited by (1,000)

Items 101–200 of 1,000

  1. Losartan treatment enhances chemotherapy efficacy and reduces ascites in ovarian cancer models by normalizing the tumor stroma
    Yanxia Zhao, Jinghong Cao, Alexander Melamed, Michael J. Worley, Allison Ann Gockley, Dennis Jones, Hadi Tavakoli Nia, Yanling Zhang, Triantafyllos Stylianopoulos, Ashwin Srinivasan Kumar et al. · 2019 · Proceedings of the National Academy of Sciences
  2. Pharmacological and physical vessel modulation strategies to improve EPR-mediated drug targeting to tumors
    Ojha, Tarun, Pathak, Vertika, Shi, Yang, Hennink, Wim E., Moonen, Chrit T.W., Storm, Gert, Kiessling, Fabian, Lammers, Twan · 2017 · Advanced Drug Delivery Reviews
  3. Exploiting nanotechnology to overcome tumor drug resistance: Challenges and opportunities
    Ameya R. Kirtane, Stephen Kalscheuer, Jayanth Panyam · 2013 · Advanced Drug Delivery Reviews
  4. Hydrophobic IR780 encapsulated in biodegradable human serum albumin nanoparticles for photothermal and photodynamic therapy
    Chenxiao Jiang, Hao Cheng, Ahu Yuan, Xiaolei Tang, Jinhui Wu, Yiqiao Hu · 2014 · Acta Biomaterialia
  5. Nanoparticles for modulating tumor microenvironment to improve drug delivery and tumor therapy
    Yang, Shu, Gao, Huile · 2017 · Pharmacological Research
  6. Micro/nano-bubble-assisted ultrasound to enhance the EPR effect and potential theranostic applications
    Lei Duan, Yang Li, Juan Jin, Fang Yang, Dong Liu, Ke Hu, Qinxin Wang, Yuanbin Yue, Ning Gu · 2019 · Theranostics
  7. Thermal immuno-nanomedicine in cancer
    Zhe Yang, Di Gao, Jing Zhao, Gaojie Yang, Ming Guo, Ying Wang, Xuechun Ren, Jong Seung Kim, Lin Jin, Zhongmin Tian et al. · 2023 · Nature Reviews Clinical Oncology
  8. Physical Properties of Nanoparticles That Result in Improved Cancer Targeting
    Randa Zein, Wissam Sharrouf, Kim A. Selting · 2020 · Journal of Oncology
  9. Current Challenges of Cancer Anti-angiogenic Therapy and the Promise of Nanotherapeutics
    Abdalla, Ahmed M.E., Xiao, Lin, Ullah, Muhammad Wajid, Yu, Miao, Ouyang, Chenxi, Yang, Guang · 2018 · Theranostics
  10. Electrochemical detection of nanoparticles by ‘nano-impact’ methods
    Wei Cheng, Richard G. Compton · 2014 · TrAC Trends in Analytical Chemistry
  11. Nanomedicine strategies to overcome the pathophysiological barriers of pancreatic cancer
    Pavan P. Adiseshaiah, Rachael M. Crist, Sara S. Hook, Scott E. McNeil · 2016 · Nature Reviews Clinical Oncology
  12. Advances of medical nanorobots for future cancer treatments
    Xiangyi Kong, Peng Gao, Jing Wang, Yi Fang, Kuo Chu Hwang · 2023 · Journal of Hematology & Oncology
  13. Mechanisms of enhanced drug delivery in brain metastases with focused ultrasound-induced blood–tumor barrier disruption
    Costas Arvanitis, Vasileios Askoxylakis, Yutong Guo, Meenal Datta, Jonas Kloepper, Gino B. Ferraro, Miguel O. Bernabéu, Dai Fukumura, Nathan Judson McDannold, Rakesh K. Jain · 2018 · Proceedings of the National Academy of Sciences
  14. Interstitial fluid flow in cancer: implications for disease progression and treatment
    Jennifer M. Munson, Adrian C. Shieh · 2014 · Cancer Management and Research
  15. Nanoplatform Assembled from a CD44-Targeted Prodrug and Smart Liposomes for Dual Targeting of Tumor Microenvironment and Cancer Cells
    Lv, Yaqi, Xu, Chaoran, Zhao, Xiangmei, Lin, Chenshi, Yang, Xin, Xin, Xiaofei, Zhang, Li, Qin, Chao, Han, Xiaopeng, Yang, Lei et al. · 2018 · ACS Nano
  16. Hyperthermia and smart drug delivery systems for solid tumor therapy
    Ann L.B. Seynhaeve, Mohamadreza Amin, Dieter Haemmerich, Gerard C. van Rhoon, Timo L.M. ten Hagen · 2020 · Advanced Drug Delivery Reviews
  17. Designing nanomedicine for immuno-oncology
    Wen Jiang, Christina A. Von Roemeling, Yuanxin Chen, Yaqing Qie, Xiujie Liu, Jianzhu Chen, Betty Y.S. Kim · 2017 · Nature Biomedical Engineering
  18. Remodeling the Tumor Microenvironment with Emerging Nanotherapeutics
    Qin Chen, Guangxuan Liu, Shuo Liu, Hongyan Su, Yue Wang, Jingyu Li, Cong Luo · 2017 · Trends in Pharmacological Sciences
  19. Advanced engineered nanoparticulate platforms to address key biological barriers for delivering chemotherapeutic agents to target sites
    Jun Cao, Dennis Huang, Nicholas A. Peppas · 2020 · Advanced Drug Delivery Reviews
  20. Microfluidic modelling of the tumor microenvironment for anti-cancer drug development
    Shang, Menglin, Soon, Ren Hao, Lim, Chwee Teck, Khoo, Bee Luan, Han, Jongyoon · 2019 · Lab on a Chip
  21. Photoswitchable nanoparticles for in vivo cancer chemotherapy
    Rong Tong, Homer H. Chiang, Daniel S. Kohane · 2013 · Proceedings of the National Academy of Sciences
  22. Renal‐Clearable Nickel‐Doped Carbon Dots with Boosted Photothermal Conversion Efficiency for Multimodal Imaging‐Guided Cancer Therapy in the Second Near‐Infrared Biowindow
    Boshi Tian, Shikai Liu, Lili Feng, Shaohua Liu, Shili Gai, Yunlu Dai, Lisi Xie, Bin Liu, Piaoping Yang, Yanli Zhao · 2021 · Advanced Functional Materials
  23. Mesoporous Silica Nanoparticle-Supported Lipid Bilayers (Protocells) for Active Targeting and Delivery to Individual Leukemia Cells
    Paul N. Durfee, Yu‐Shen Lin, Darren Robert Dunphy, Ayșe Jane Muñiz, Kimberly S. Butler, Kevin R. Humphrey, Amanda J. Lokke, Jacob Ongudi Agola, Stanley S. Chou, I‐Ming Chen et al. · 2016 · ACS Nano
  24. Improving cancer therapy through the nanomaterials-assisted alleviation of hypoxia
    Abhishek Sahu, Inchan Kwon, Giyoong Tae · 2019 · Biomaterials
  25. Tumor extravasation and infiltration as barriers of nanomedicine for high efficacy: The current status and transcytosis strategy
    Quan Zhou, Chengyuan Dong, Wufa Fan, Haiping Jiang, Jiajia Xiang, Nasha Qiu, Ying Piao, Tao Xie, Yingwu Luo, Zichen Li et al. · 2020 · Biomaterials
  26. Targeting Tumor-Associated Fibroblasts for Therapeutic Delivery in Desmoplastic Tumors
    Miao, Lei, Liu, Qi, Lin, C. Michael, Luo, Cong, Wang, Yuhua, Liu, Lina, Yin, Weiyan, Hu, Shihao, Kim, William Y., Huang, Leaf · 2017 · Cancer Research
  27. Overcoming the biological barriers in the tumor microenvironment for improving drug delivery and efficacy
    Zhou, Yang, Chen, Xianchun, Cao, Jun, Gao, Huile · 2020 · Journal of Materials Chemistry B
  28. Exerting Enhanced Permeability and Retention Effect Driven Delivery by Ultrafine Iron Oxide Nanoparticles with T1–T2 Switchable Magnetic Resonance Imaging Contrast
    Liya Wang, Jing Huang, Hongbo Chen, Hui Chen Wu, Yaolin Xu, Yuancheng Li, Hong Liang Yi, Yongqiang A. Wang, Lily P H Yang, Hui Z. Mao · 2017 · ACS Nano
  29. Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy
    Vikash P. Chauhan, Ivy X. Chen, Rong Tong, Mei Rosa Ng, John D. Martin, Kamila Naxerova, Michelle W. Wu, Peigen Huang, Yves Boucher, Daniel S. Kohane et al. · 2019 · Proceedings of the National Academy of Sciences
  30. Recent Advances in Nanostrategies Capable of Overcoming Biological Barriers for Tumor Management
    Da Huo, Xiqun Jiang, Yong Hu · 2019 · Advanced Materials
  31. Improving drug accumulation and photothermal efficacy in tumor depending on size of ICG loaded lipid-polymer nanoparticles
    Pengfei Zhao, Mingbin Zheng, Caixia Yue, Zhenyu Luo, Ping Gong, Guanhui Gao, Zonghai Sheng, Cuifang Zheng, Lintao Cai · 2014 · Biomaterials
  32. Modulating tumor hypoxia by nanomedicine for effective cancer therapy
    Jahanban‐Esfahlan, Rana, de la Guardia, Miguel, Ahmadi, Delshad, Yousefi, Bahman · 2018 · Journal of Cellular Physiology
  33. Magnetic Iron Oxide Nanoparticles As Drug Carriers: Clinical Relevance
    Kheireddine El‐Boubbou · 2018 · Nanomedicine
  34. Thirty Years of Cancer Nanomedicine: Success, Frustration, and Hope
    Lucia Salvioni, Maria Antonietta Rizzuto, Jessica Armida Bertolini, Laura Pandolfi, Miriam Colombo, Davide Prosperi · 2019 · Cancers
  35. Enhancing tumor penetration of nanomedicines
    Sun, Qingxue, Ojha, Tarun, Kiessling, Fabian, Lammers, Twan, Shi, Yang · 2017 · Biomacromolecules
  36. EPR-effect: Utilizing size-dependent Nanoparticle Delivery to Solid Tumors
    Triantafyllos Stylianopoulos · 2013 · Therapeutic Delivery
  37. Nanogel carrier design for targeted drug delivery
    David M. Eckmann, Russell J. Composto, Andrew Tsourkas, Vladimir R. Muzykantov · 2014 · Journal of Materials Chemistry B
  38. Improved intratumoral nanoparticle extravasation and penetration by mild hyperthermia
    Li Li, Timo L.M. ten Hagen, Michiel Bolkestein, Astrid Gasselhuber, Jeremy Yatvin, Gerard C. van Rhoon, Alexander M.M. Eggermont, Dieter Haemmerich, Gerben A. Koning · 2013 · Journal of Controlled Release
  39. Mitochondria-Targeted and Ultrasound-Activated Nanodroplets for Enhanced Deep-Penetration Sonodynamic Cancer Therapy
    Liang Zhang, Hengjing Yi, Jiao Song, Ju Huang, Ke Yang, Bin Tan, Dong Wang, Nanlan Yang, Zhigang Wang, Xingsheng Li · 2019 · ACS Applied Materials & Interfaces
  40. Personalized Nanomedicine
    Twan Lammers, Larissa Yokota Rizzo, Gert Storm, Fabian M. Kiessling · 2012 · Clinical Cancer Research
  41. Targeting the tumour vasculature: from vessel destruction to promotion
    Sophie Guelfi, Kairbaan Hodivala‐Dilke, Gabriele Bergers · 2024 · Nature reviews. Cancer
  42. Impact of Semiconducting Perylene Diimide Nanoparticle Size on Lymph Node Mapping and Cancer Imaging
    Zhèn Yáng, Rui Tian, Jinjun Wu, Quli Fan, Bryant C. Yung, Gang Niu, Orit Jacobson, Zhantong Wang, Gang Liu, Guocan Yu et al. · 2017 · ACS Nano
  43. Tumor angiogenesis revisited: Regulators and clinical implications
    Roberto Ronca, Mohammed Benkheil, Stefania Maria Filomena Mitola, Sofie Struyf, Sandra Liekens · 2017 · Medicinal Research Reviews
  44. TGF-β inhibition combined with cytotoxic nanomedicine normalizes triple negative breast cancer microenvironment towards anti-tumor immunity
    Myrofora Panagi, Chrysovalantis Voutouri, Fotios Mpekris, Panagiotis Papageorgis, Margaret R. Martin, John D. Martin, Philippos Demetriou, Chryso Pierides, Christiana Polydorou, Andreas Stylianou et al. · 2020 · Theranostics
  45. Smart chemistry in polymeric nanomedicine
    Rong Tong, Li Tang, Liang Ma, Chunlai Tu, Ryan Baumgartner, Jianjun Cheng · 2014 · Chemical Society Reviews
  46. Cooperativity Principles in Self-Assembled Nanomedicine
    Yang Li, Yiguang Wang, Gang Huang, Jinming Gao · 2018 · Chemical Reviews
  47. Probing nanoparticle translocation across the permeable endothelium in experimental atherosclerosis
    YongTae Kim, Mark E. Lobatto, Tomohiro Kawahara, Bomy Lee Chung, Aneta J. Mieszawska, Brenda L. Sánchez-Gaytán, François Fay, Max L. Senders, Claudia Calcagno, Jacob R. Becraft et al. · 2014 · Proceedings of the National Academy of Sciences
  48. Current Approaches for Improving Intratumoral Accumulation and Distribution of Nanomedicines
    Mikhail O. Durymanov, Andrey A. Rosenkranz, Alexander S. Sobolev · 2015 · Theranostics
  49. Merging the best of both worlds: hybrid lipid-enveloped matrix nanocomposites in drug delivery
    Koen Raemdonck, Kevin Braeckmans, Jo Demeester, Stefaan C. De Smedt · 2013 · Chemical Society Reviews
  50. Photosensitization Priming of Tumor Microenvironments Improves Delivery of Nanotherapeutics via Neutrophil Infiltration
    Dafeng Chu, Xinyue Dong, Qi Zhao, Jingkai Gu, Zhenjia Wang · 2017 · Advanced Materials
  51. Supramolecularly Engineered NIR‐II and Upconversion Nanoparticles In Vivo Assembly and Disassembly to Improve Bioimaging
    Mengyao Zhao, Benhao Li, Peiyuan Wang, Lingfei Lu, Zhengcheng Zhang, Lu Liu, Shangfeng Wang, Dandan Li, Rui Wang, Fan Zhang · 2018 · Advanced Materials
  52. An Updated Review on EPR-Based Solid Tumor Targeting Nanocarriers for Cancer Treatment
    Majid Sharifi, William Chi Shing Cho, Asal Ansariesfahani, Rahil Tarharoudi, Hedyeh Malekisarvar, Soyar Sari, Samir Haj Bloukh, Zehra Edis, Mohamadreza Amin, Jason P. Gleghorn et al. · 2022 · Cancers
  53. Engineered strategies to enhance tumor penetration of drug-loaded nanoparticles
    Souri, Mohammad, Soltani, M., Moradi Kashkooli, Farshad, Kiani Shahvandi, Mohammad · 2022 · Journal of Controlled Release
  54. Tumor penetrability and anti-angiogenesis using iRGD-mediated delivery of doxorubicin-polymer conjugates
    Ke Wang, Xiaofeng Zhang, Yang Liu, Chang Liu, Baohong Jiang, Yanyan Jiang · 2014 · Biomaterials
  55. Nanodrug Delivery Systems Modulate Tumor Vessels to Increase the Enhanced Permeability and Retention Effect
    Huang, Dong, Sun, Lingna, Huang, Leaf, Chen, Yanzuo · 2021 · Journal of Personalized Medicine
  56. Reengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity
    John D. Martin, Dai Fukumura, Dan Gabriel Duda, Yves Boucher, Rakesh K. Jain · 2016 · Cold Spring Harbor Perspectives in Medicine
  57. Pathological angiogenesis and inflammation in tissues
    Ji-Hak Jeong, Uttam Ojha, You Mie Lee · 2020 · Archives of Pharmacal Research
  58. Biological Effects of Nanoparticles on Macrophage Polarization in the Tumor Microenvironment
    Derek Reichel, Manisha Tripathi, J. Manuel Perez · 2018 · Nanotheranostics
  59. Mesoporous silica/organosilica nanoparticles: Synthesis, biological effect and biomedical application
    Bowen Yang, Yu Chen, Jianlin Shi · 2019 · Materials Science and Engineering R Reports
  60. First Experience of 18F-Alfatide in Lung Cancer Patients Using a New Lyophilized Kit for Rapid Radiofluorination
    Weixing Wan, Ning Guo, Donghui Pan, Chunjing Yu, Yuan Weng, Shineng Luo, Hong Yan Ding, Yuping Xu, Lizhen Wang, Lixin Lang et al. · 2013 · Journal of Nuclear Medicine
  61. Sonoporation enhances liposome accumulation and penetration in tumors with low EPR
    Benjamin Theek, Maike Baues, Tarun Ojha, Diana Möckel, Seena Koyadan Veettil, Julia Steitz, Louis van Bloois, Gert Storm, Fabian M. Kiessling, Twan Lammers · 2016 · Journal of Controlled Release
  62. Polymer encapsulation of ruthenium complexes for biological and medicinal applications
    Elise Villemin, Yih Ching Ong, C.M. Thomas, Gilles Gasser · 2019 · Nature Reviews Chemistry
  63. The Solid Mechanics of Cancer and Strategies for Improved Therapy
    Triantafyllos Stylianopoulos · 2016 · Journal of Biomechanical Engineering
  64. Photonanomedicine: a convergence of photodynamic therapy and nanotechnology
    Girgis Obaid, Mans Broekgaarden, Anne‐Laure Bulin, Huang‐Chiao Huang, Jerrin Kuriakose, Joyce Liu, Tayyaba G. Hasan · 2016 · Nanoscale
  65. The challenges facing block copolymer micelles for cancer therapy: In vivo barriers and clinical translation
    Sina Eetezadi, Sandra N. Ekdawi, Christine J. Allen · 2014 · Advanced Drug Delivery Reviews
  66. Rational Design of Nanoparticles with Deep Tumor Penetration for Effective Treatment of Tumor Metastasis
    Zhiwen Zhang, Hong Wang, Tao Tan, Jie Li, Zhiwan Wang, Yaping Li · 2018 · Advanced Functional Materials
  67. Tumor‐Exocytosed Exosome/Aggregation‐Induced Emission Luminogen Hybrid Nanovesicles Facilitate Efficient Tumor Penetration and Photodynamic Therapy
    Daoming Zhu, Yanhong Duo, Meng Suo, Yonghua Zhao, Ligang Xia, Zheng Zheng, Li Yang, Ben Zhong Tang · 2020 · Angewandte Chemie International Edition
  68. Pharmacokinetics of magnetic iron oxide nanoparticles for medical applications
    Julia Nowak‐Jary, Beata Machnicka · 2022 · Journal of Nanobiotechnology
  69. Breaking through the basement membrane barrier to improve nanotherapeutic delivery to tumours
    Qin Wang, Qirui Liang, Jiaxiang Dou, Han Zhou, Cici Zeng, Huimin Pan, Yanqiong Shen, Quan Li, Yi Liu, David Tai Leong et al. · 2023 · Nature Nanotechnology
  70. Mesenchymal stem cell-based cell engineering with multifunctional mesoporous silica nanoparticles for tumor delivery
    Xinglu Huang, Fan Zhang, Hui Wang, Gang Niu, Ki Young Choi, Magdalena Swierczewska, Guofeng Zhang, Haokao Gao, Zhe Wang, Lei Zhu et al. · 2012 · Biomaterials
  71. Numerical modeling of drug delivery in a dynamic solid tumor microvasculature
    Mostafa Sefidgar, Madjid Soltani, Kaamran Raahemifar, M. Sadeghi, Hossein Bazmara, Majid Bazargan, Mojtaba Mousavi Naeenian · 2015 · Microvascular Research
  72. Tumor Microenvironment Targeted Nanotherapy
    Clara Fernandes, Divya Suares, Mayur C. Yergeri · 2018 · Frontiers in Pharmacology
  73. Magnetically Actuated Drug Delivery Helical Microrobot with Magnetic Nanoparticle Retrieval Ability
    Hyoryong Lee, Dong‐In Kim, Su-hyun Kwon, Sukho Park · 2021 · ACS Applied Materials & Interfaces
  74. Lipase‐Triggered Water‐Responsive “Pandora's Box” for Cancer Therapy: Toward Induced Neighboring Effect and Enhanced Drug Penetration
    Cheng Wang, Shaoqing Chen, Yunxin Wang, Xuerong Liu, Fuqiang Hu, Jihong Sun, Hong Yuan · 2018 · Advanced Materials
  75. Towards principled design of cancer nanomedicine to accelerate clinical translation
    Souri, Mohammad, Soltani, M., Moradi Kashkooli, Farshad, Kiani Shahvandi, Mohammad, Chiani, Mohsen, Shariati, Fatemeh Sadat, Mehrabi, Mohammad Reza, Munn, Lance L. · 2022 · Materials Today Bio
  76. Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy
    Adapala, R K, Thoppil, R J, Ghosh, K, Cappelli, H C, Dudley, A C, Paruchuri, S, Keshamouni, V, Klagsbrun, M, Meszaros, J G, Chilian, W M et al. · 2016 · Oncogene
  77. Radiation effects on the tumor microenvironment: Implications for nanomedicine delivery
    Shawn Stapleton, David Anthony Jaffray, Michael Milosevic · 2016 · Advanced Drug Delivery Reviews
  78. Extracellular matrix physical properties govern the diffusion of nanoparticles in tumor microenvironment
    Xiaocong He, Yuanyuan Yang, Yulong Han, Chunyu Cao, Zhongbin Zhang, Lingxiao Li, Cailan Xiao, Hui Guo, Lin Wang, Lichun Han et al. · 2022 · Proceedings of the National Academy of Sciences
  79. Modulating the Tumor Microenvironment to Enhance Tumor Nanomedicine Delivery
    Zhang, Bo, Hu, Yu, Pang, Zhiqing · 2017 · Frontiers in Pharmacology
  80. Nano–Bio Interactions in Cancer: From Therapeutics Delivery to Early Detection
    Yuan Liu, Junqing Wang, Qingqing Xiong, Daniel Hornburg, Wei Tao, Omid Cameron Farokhzad · 2020 · Accounts of Chemical Research
  81. Mathematical modeling in cancer nanomedicine: a review
    Prashant Dogra, Joseph D. Butner, Yao-Li Chuang, Sergio Caserta, Shreya Goel, C. Jeffrey Brinker, Vittorio Cristini C, Zhihui Wang · 2019 · Biomedical Microdevices
  82. Size shrinkable drug delivery nanosystems and priming the tumor microenvironment for deep intratumoral penetration of nanoparticles
    Yimin Niu, Jianhua Zhu, Yang Li, Huihui Shi, Yaxiang Gong, Rui Li, Qiang Huo, Tao Ma, Yang Liu · 2018 · Journal of Controlled Release
  83. Enhanced Radiosensitization by Gold Nanoparticles with Acid‐Triggered Aggregation in Cancer Radiotherapy
    Yumin Zhang, Fan Huang, Chunhua Ren, Jinjian Liu, Lijun Yang, Shizhu Chen, Jinglin Chang, Cuihong Yang, Weiwei Wang, Chuangnian Zhang et al. · 2019 · Advanced Science
  84. Exploring the Tumor Microenvironment with Nanoparticles
    Lei Miao, Leaf Huang · 2015 · Cancer treatment and research
  85. NIR‐II‐Excited Intravital Two‐Photon Microscopy Distinguishes Deep Cerebral and Tumor Vasculatures with an Ultrabright NIR‐I AIE Luminogen
    Wang, Shaowei, Liu, Jie, Goh, Chi Ching, Ng, Lai Guan, Liu, Bin · 2019 · Advanced Materials
  86. Remodeling Tumor Vasculature to Enhance Delivery of Intermediate-Sized Nanoparticles
    Wen Jiang, Yuhui Huang, Yi An, Betty Y.S. Kim · 2015 · ACS Nano
  87. Improved anticancer effects of albumin-bound paclitaxel nanoparticle via augmentation of EPR effect and albumin-protein interactions using S-nitrosated human serum albumin dimer
    Ryo Kinoshita, Yu Ishima, Victor Tuan Giam Chuang, Hideaki Nakamura, Jun Qun Fang, Hiroshi Watanabe, Taro Shimizu, Keiichiro Okuhira, Tatsuhiro Ishida, Hiroshi Maeda et al. · 2017 · Biomaterials
  88. Metabolic modulation via mTOR pathway and anti-angiogenesis remodels tumor microenvironment using PD-L1-targeting codelivery
    Binfan Chen, Ang Gao, Bin Tu, Yonghui Wang, Xiaolu Yu, Yingshu Wang, Yanfeng Xiu, Bing Wang, Yakun Wan, Yongzhuo Huang · 2020 · Biomaterials
  89. Lipid-Coated Cisplatin Nanoparticles Induce Neighboring Effect and Exhibit Enhanced Anticancer Efficacy
    Shutao Guo, Yuhua Wang, Lei Miao, Zhenghong Xu, C. Michael Lin, Yuan Zhang, Leaf Huang · 2013 · ACS Nano
  90. Machine-learning-assisted single-vessel analysis of nanoparticle permeability in tumour vasculatures
    Zhu, Mingsheng, Zhuang, Jie, Li, Zhe, Liu, Qiqi, Zhao, Rongping, Gao, Zhanxia, Midgley, Adam C., Qi, Tianyi, Tian, Jingwei, Zhang, Zhixuan et al. · 2023 · Nature Nanotechnology
  91. Self-sufficing H2O2-responsive nanocarriers through tumor-specific H2O2 production for synergistic oxidation-chemotherapy
    Junjie Li, Wendong Ke, Lei Wang, Mingming Huang, Wei Yin, Ping Zhang, Qixian Chen, Zhishen Ge · 2016 · Journal of Controlled Release
  92. Nanoparticle Targeting of Neutrophils for Improved Cancer Immunotherapy
    Dafeng Chu, Qi Zhao, Jian Yu, Faya Zhang, Hui Zhang, Zhenjia Wang · 2016 · Advanced Healthcare Materials
  93. Tranilast-induced stress alleviation in solid tumors improves the efficacy of chemo- and nanotherapeutics in a size-independent manner
    Panagiotis Papageorgis, Christiana Polydorou, Fotios Mpekris, Chrysovalantis Voutouri, Eliana A. Agathokleous, Constantina P. Kapnissi‐Christodoulou, Triantafyllos Stylianopoulos · 2017 · Scientific Reports
  94. Tumour microenvironment responsive nanoconstructs for cancer theranostic
    Arif Gulzar, Jiating Xu, Chen Wang, Fei He, Dan Yang, Shili Gai, Piaoping Yang, Jun Lin, Dayong Jin, Bengang Xing · 2019 · Nano Today
  95. Active Transportation of Liposome Enhances Tumor Accumulation, Penetration, and Therapeutic Efficacy
    Guowei Wang, Bihan Wu, Qunying Li, Siqin Chen, Xiaoqin Jin, Yajing Liu, Zhuxian Zhou, Youqing Shen, Pintong Huang · 2020 · Small
  96. Cationic Nanoparticles Have Superior Transvascular Flux into Solid Tumors: Insights from a Mathematical Model
    Triantafyllos Stylianopoulos, Konstantinos Soteriou, Dai Fukumura, Rakesh K. Jain · 2012 · Annals of Biomedical Engineering
  97. Metformin Inhibits Metastatic Breast Cancer Progression and Improves Chemosensitivity by Inducing Vessel Normalization via PDGF-B Downregulation
    Wang, Ji-Chang, Li, Guang-Yue, Wang, Bo, Han, Su-Xia, Sun, Xin, Jiang, Yi-Na, Shen, Yan-Wei, Zhou, Can, Feng, Jun, Lu, Shao-Ying et al. · 2019 · Journal of Experimental & Clinical Cancer Research
  98. Renal‐Clearable PEGylated Porphyrin Nanoparticles for Image‐Guided Photodynamic Cancer Therapy
    Liang Cheng, Dawei Jiang, Anyanee Kamkaew, Hector F. Valdovinos, Hyung‐Jun Im, Liangzhu Feng, Christopher G. England, Shreya Goel, Todd E. Barnhart, Zhuang Liu et al. · 2017 · Advanced Functional Materials
  99. Overcoming Physiological Barriers to Nanoparticle Delivery—Are We There Yet?
    Oliver S. Thomas, Wilfried Weber · 2019 · Frontiers in Bioengineering and Biotechnology
  100. Dexamethasone Increases Cisplatin-Loaded Nanocarrier Delivery and Efficacy in Metastatic Breast Cancer by Normalizing the Tumor Microenvironment
    John D. Martin, Myrofora Panagi, Chenyu Wang, Thahomina Khan, Margaret R. Martin, Chrysovalantis Voutouri, Kazuko Toh, Panagiotis Papageorgis, Fotios Mpekris, Christiana Polydorou et al. · 2019 · ACS Nano