The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
A multiphase transitioning peptide hydrogel for suturing ultrasmall vessels
Open accessAbstract
Many surgeries are complicated by the need to anastomose, or reconnect, micron-scale vessels. Although suturing remains the gold standard for anastomosing vessels, it is difficult to place sutures correctly through collapsed lumen, making the procedure prone to failure. Here, we report a multi-phase transitioning peptide hydrogel that can be injected into the lumen of vessels to facilitate suturing. The peptide, which contains a photocaged glutamic acid, forms a solid-like gel in a syringe and can be shear-thin delivered to the lumen of collapsed vessels (where it distends the vessel), and the space between two vessels (where it is used to approximate the vessel ends). Suturing is performed directly through the gel. Light is used to initiate the final gel-sol phase transition that disrupts the hydrogel network, allowing the gel to be removed and blood flow to resume. This gel adds a new tool to the armamentarium for micro- and supermicrosurgical procedures.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Calculation of thermal noise in atomic force microscopy
Butt, H. J., & Jaschke, M. (1995) · Nanotechnology · doi:10.1088/0957-4484/6/1/001 · Cited by 1,589
Matsuzaki, M., Ellis-Davies, G. C. R., Nemoto, T., Miyashita, Y., Iino, M., & Kasai, H. (2001) · Nature Neuroscience · doi:10.1038/nn736 · Cited by 1,563 · cited 1×
“The MNI cage, chosen for its efficient aqueous photolysis and cytocompatibility 19,20 , is incorporated at position 14 of APC1's primary sequence.”
Cited by
Biomimetic peptide self-assembly for functional materials
Levin, A., Hakala, T. A., Schnaider, L., Bernardes, G. J. L., Gazit, E., & Knowles, T. P. J. (2020) · Nature Reviews Chemistry · doi:10.1038/s41570-020-0215-y · Cited by 853
Self‐Assembled Peptide‐Based Nanomaterials for Biomedical Imaging and Therapy
Qi, G., Gao, Y., Wang, L., & Wang, H. (2018) · Advanced Materials · doi:10.1002/adma.201703444 · Cited by 527
Photoresponsive biomaterials for targeted drug delivery and 4D cell culture
Ruskowitz, E. R., & DeForest, C. A. (2018) · Nature Reviews Materials · doi:10.1038/natrevmats.2017.87 · Cited by 398
Amino Acids and Peptide‐Based Supramolecular Hydrogels for Three‐Dimensional Cell Culture
Dou, X., & Feng, C. (2017) · Advanced Materials · doi:10.1002/adma.201604062 · Cited by 355
Self-Assembling Peptide EAK16 and RADA16 Nanofiber Scaffold Hydrogel
Gelain, F., Luo, Z., & Zhang, S. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00690 · Cited by 267
Metadata
- Authors
- Smith, D. J., Brat, G. A., Medina, S. H., Tong, D., Huang, Y., Grahammer, J., Furtmüller, G. J., Oh, B. C., Nagy-Smith, K. J., Walczak, P., Brandacher, G., & Schneider, J. P.
- Venue
- Nature Nanotechnology
- Published
- 2015-11-02
- Volume
- 11
- Issue
- 1
- Pages
- 95-102
- ISSN
- 1748-3387 (ISSN-L)
- 1748-3395
- OpenAlex
- W2225592990
- Cited by
- 169
- References
- 2
- FWCI
- 5.29
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: A multiphase transitioning peptide hydrogel for suturing ultrasmall vessels. https://app.cochat.ai/papers/10.1038/nnano.2015.238
- The paper
- Smith, D. J., Brat, G. A., Medina, S. H., Tong, D., Huang, Y., Grahammer, J., Furtmüller, G. J., Oh, B. C., Nagy-Smith, K. J., Walczak, P., Brandacher, G., & Schneider, J. P. (2016). A multiphase transitioning peptide hydrogel for suturing ultrasmall vessels. Nature Nanotechnology. https://doi.org/10.1038/nnano.2015.238
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
