Two-day radial-arm water maze learning and memory task; robust resolution of amyloid-related memory deficits in transgenic mice
Alamed, Jennifer, Wilcock, Donna M, Diamond, David M, Gordon, Marcia N, Morgan, Dave·2006·Nature Protocols
Cited by (258)
Items 201–258 of 258
- Comparative Evaluation of Aminoguanidine, Semicarbazide and Thiosemicarbazide Treatment for Methylglyoxal-Induced Neurological Toxicity in Experimental ModelsNoushin Nikray, Nikoo Abharian, Shahin Jafari Ashtiani, Farzad Kobarfard, Mehrdad Faizi · 2024 · Iranian journal of pharmaceutical research
- ECSIT prevents Alzheimer’s disease pathology by regulating neuronal mitochondrial ROS and mitophagyAlice Lepelley, Lauren S. Vaughn, Agnieszka Staniszewski, Hong Zhang, Fang Du, Peter Koppensteiner, Zeljko Tomljanovic, Flávia Raquel Gonçalves Carneiro, Andrew F. Teich, Ipe Ninan et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Impaired 26S proteasome causes learning and memory deficiency and induces neuroinflammation mediated by NF-κB in miceChrista C. Huber, Eduardo Alberto Callegari, Maria Paez, Xiaoping Li, Abena Dwamena, Hongmin Wang · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Chronic psychosocial stress reveals Alzheimer’s disease in a novel at-risk rat modelKarim A. Alkadhi · 2023 · Journal of Contemporary Medical Sciences
- Influence of Host Age on Intracranial AAV9 TauP301L Induced TauopathyAmber M. Tetlow, Brianna M. Jackman, Mohammed M. Alhadidy, Varshini Perumal, David Morgan, Marcia N. Gordon · 2023 · Journal of Alzheimer s Disease
- Animal models of Alzheimer’s DiseaseDavid Morgan · 2017 · Oxford University Press eBooks
- Targeting the Hsp90/Aha1 Complex for the Treatment of TauopathiesLindsey B. Shelton · 2018 · Digital Commons - University of South Florida (University of South Florida)
- Early postnatal inhibition of neurosteroid synthesis changes the later-life adverse outcome of neonatal asphyxia in ratsBjörn Welzel, Ricardo Schmidt, Wolfgang Löscher · 2025 · Neuropharmacology
- PP2A methylesterase, PME‐1, and PP2A methyltransferase, LCMT‐1, control sensitivity to impairments caused by injury‐related oligomeric tauSowmya N. Sundaresh, Edward W. Vogel, Christopher D. Hue, Hong Zhang, Anna Staniszewski, Hanna L. Berman, Zafar Gill, Kesava R. Asam, Siqi Liang, Liwei Shen et al. · 2025 · Alzheimer s & Dementia
- Human Brain Contusions Contain Pathogenic Transmissible Species that Induce Progressive Cognitive Decline and Tau Pathology in MiceGloria Vegliante, Francesca Pischiutta, Elena Restelli, Federico Moro, Maria Antonietta Chiaravalloti, Ilaria Raimondi, Ilaria Bertani, Ilaria Lisi, Eliana Sammali, Rosaria Pascente et al. · 2025 · Annals of Neurology
- Disruption of the brain-spleen axis impairs monocyte-microglia communication and accelerates disease progression in a mouse model of amyloidosisTommaso Croese, Miguel Angel Abellanas, Hodaya Polonsky, Michal Arad, Javier María Peralta Ramos, Yuliya Androsova, Serena Riccitelli, Sedi Medina, Francesca Palmas, Romano Strobelt et al. · 2026 · Nature Communications
- A murine model of amyloid enhanced tauopathy: progressive changes in tau pathology and behaviorDylan J. Finneran, Taylor Desjarlais, Brianna M. Jackman, David Morgan, Marcia N. Gordon · 2026 · Alzheimer s & Dementia
- A murine model of amyloid‐enhanced tauopathy: Comparison of wild‐type and P301L‐tauDylan J. Finneran, Taylor Desjarlais, Brianna M. Jackman, Marcia N. Gordon, David Morgan · 2026 · Alzheimer s & Dementia
- A Novel Preclinical Rat Model of Alzheimer’s DiseaseKarim A. Alkadhi · 2019 · Neuromethods
- Sleeve Gastrectomy Reduces Glycemia but Does Not Affect Cognitive Impairment in Lean 5xFAD MiceItia Samuel, Rachel Ben‐Haroush Schyr, Yhara Arad, Tamar Attali, Shira Azulai, Michael Bergel, Aviv Halfon, Liron Hefetz, Tamir Hirsh, Hadar Israeli et al. · 2022 · Frontiers in Neuroscience
- Mouse model of repetitive mild traumatic brain injury (investigating cognitive impairment)Lulin Li, Andy Nguyen, Jian Luo · 2022 · Elsevier eBooks
- Generation and Characterization of the First Murine Model of Alzheimer’s Disease with Mutated AβPP Inserted in a BALB/c Background (C.B6/J-APP swe )Marta Balietti, Tiziana Casoli, Belinda Giorgetti, Roberto Colangeli, Cristina Nicoletti, Moreno Solazzi, Arianna Pugliese, Fiorenzo Conti · 2023 · Journal of Alzheimer s Disease
- Mouse Testing Methods in Psychoneuroimmunology: Measuring Behavioral ResponsesSteven A. Krauklis, Albert E. Towers, Jason M. York, Tracy Baynard, Stephen J. Gainey, Gregory G. Freund, Andrew J. Steelman · 2024 · Methods in molecular biology
- A rat model of pre-clinical Alzheimer’s diseaseKarim A. Alkadhi · 2022 · Elsevier eBooks
- IL-1β regulates TRPM2 channel in astrocytes and aggravates their apoptosis during lipopolysaccharide induced cognitive impairment in miceYujiao Yang, Shuaiying Jia, Mingfei Wang, Debo Yun · 2022 · Research Square
- GRK5KO Mouse Mirrors Mild Cognitive Impairment due to Alzheimer’s DiseaseWilliam Z. Suo · 2024 · Preprints.org
- Endogenous neuronal DNA double-strand breaks are not sufficient to drive brain aging and neurodegenerationSarah Cohen, Laura Cheradame, Karishma J. B. Pratt, Sarah Ellen Collins, Ashlie Barillas, Annika Carlson, Vijay Ramani, Gaëlle Legube, Saul Villeda, R. Dyche Mullins et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- The Role of PP2A Methylation in Susceptibility and Resistance to TBI and AD-Induced NeurodegenerationOttavio Arancio, Barclay Morrison, Russell E. Nicholls, Edward W. Vogel, Christopher D. Hue · 2013
- Implications of Human Umbilical Cord Blood Cells: An Immunotherapeutic Strategy for Alzheimer's DiseaseDonna Darlington · 2014 · Digital Commons - University of South Florida (University of South Florida)
- Diet-Induced Ketosis and Calorie Restriction in Mouse Models of Alzheimer's PathologyMilene Lara Brownlow · 2013 · Digital Commons - University of South Florida (University of South Florida)
- The Characterization of the Neuropathological Consequences of Plac1 Ablation in a Mutant Mouse ModelJacob Robert Bourgeois · 2015 · Digital Commons - University of South Florida (University of South Florida)
- Chronic stress and plasticity in the limbic system: Implications for post traumatic stress disorderAnn N. Hoffman · 2013
- IMPROVING TRAUMATIC BRAIN INJURY OUTCOMES THROUGH GENE THERAPY AND EXERCISEJordan M. Taylor · 2015 · KU ScholarWorks (University of Kansas)
- THE PROTECTIVE EFFECTS OF CHRONIC CAFFEINE TREATMENT ON THE COGNITIVE FUNCTION AND SYNAPTIC PLASTICITY IN ACUTE SLEEP DEPRIVATIONIbrahim Abdulrahman Alhaider · 2010
- Tau-Directed Immunotherapy for Alzheimer's DiseaseSulana Kay Schroeder · 2017 · Digital Commons - University of South Florida (University of South Florida)
- INSULIN-LIKE GROWTH FACTOR-1 OVEREXPRESSION MEDIATES HIPPOCAMPAL REMODELING AND PLASTICITY FOLLOWING TBIErica L. Littlejohn · 2018 · UKnowledge (University of Kentucky)
- Behavioral Testing after Experimental Traumatic Brain InjuryJr., Charles S. Cox · 2016 · CRC Press eBooks
- Peripherally expressed misfolded proteins remotely disrupt brain function and aggravate stroke-induced brain injuryYanying Liu, Kalpana Subedi, Aravind Baride, Svetlana Romanova, Christa C. Huber, Xuejun Wang, Hongmin Wang · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- BEHAVIORAL AND MOLECULAR IMPACT OF CHRONIC PSYCHOSOCIAL STRESS IN A NOVEL PRE-CLINICAL MODEL OF ALZHEIMER'S DISEASEKarim A. Alkadhi · 2015
- Evaluation of Aging and Genetic Mutation Variants on TauopathyAmber M. Tetlow · 2020 · Digital Commons - University of South Florida (University of South Florida)
- Hepatoprotective effect of trypsin/chymotrypsin against olanzapine-induced non-alcoholic steatohepatitis in ratsGhada S Mahmoud, Ghada Hosny, Sally A. Sayed · 2021 · Canadian Journal of Physiology and Pharmacology
- Kif11 overexpression rescues cognition, long-term potentiation, and spine defects in mouse and cell models of Alzheimer’s diseaseEsteban Lucero, Ronald K. Freund, Noah R. Johnson, Breanna R. Dooling, Emily M. Sullivan, Olga Prikhodko, Md. Mahiuddin Ahmed, Mark L. Dell’Acqua, Heidi J. Chial, Huntington Potter · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Ca V 3.1 T-type calcium channels regulate spatial memory processing in the dorsal subiculumSrdjan M. Joksimovic, Seyed Mohammadreza Ghodsi, Jasper A. Heinsbroek, James E. Orfila, Nicolas Busquet, Vesna Tešić, Robert Valdez, Brier Fine-Raquet, Vesna Jevtović‐Todorović, Yogendra H. Raol et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Increased Expression of KIF11/Kinesin5 Offsets Alzheimer Aβ-Mediated Toxicity and Cognitive Dysfunction in Cell Culture, Mice, and HumansEsteban Lucero, Ronald K. Freund, Alexandra N. Smith, Noah Johnson, Breanna R. Dooling, Emily M. Sullivan, Olga Prikhodko, Md. Mahiuddin Ahmed, David Alan Bennett, Timothy J. Hohman et al. · 2022 · SSRN Electronic Journal
- Experimental models and behavioral screening tests in Alzheimer's Drug development: A ReviewBijesh Vatakkeel, R. Mythreyi, Siju EN · 2024 · Research Journal of Pharmacy and Technology
- Homeostatic Activation of 26S Proteasomes by Protein Kinase A Protects against Cardiac and Neurobehavior Malfunction in Alzheimer’s Disease MiceAnand Chakroborty, Saima Ejaz, Jack O. Sternburg, Yasin Asadi, Mingqi Cai, Abena Dwamena, Samiksha Giri, Oluwagbemisola Adeniji, Md Salim Ahammed, Erin Gilstrap et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Additional file 3 of Semaphorin 4D is upregulated in neurons of diseased brains and triggers astrocyte reactivityElizabeth E. Evans, Mishra, Vikas, Crystal L. Mallow, Elaine M. Gersz, Leslie Balch, Alan P. Howell, Christine A. Reilly, Ernest Smith, Terrence Lee Fisher, Maurice Zauderer · 2022 · Figshare
- Additional file 4 of Semaphorin 4D is upregulated in neurons of diseased brains and triggers astrocyte reactivityElizabeth E. Evans, Mishra, Vikas, Crystal L. Mallow, Elaine M. Gersz, Leslie Balch, Alan P. Howell, Christine A. Reilly, Ernest Smith, Terrence Lee Fisher, Maurice Zauderer · 2022 · Figshare
- Additional file 2 of Semaphorin 4D is upregulated in neurons of diseased brains and triggers astrocyte reactivityElizabeth E. Evans, Mishra, Vikas, Crystal L. Mallow, Elaine M. Gersz, Leslie Balch, Alan P. Howell, Christine A. Reilly, Ernest Smith, Terrence Lee Fisher, Maurice Zauderer · 2022 · Figshare
- Additional file 1 of Semaphorin 4D is upregulated in neurons of diseased brains and triggers astrocyte reactivityElizabeth E. Evans, Mishra, Vikas, Crystal L. Mallow, Elaine M. Gersz, Leslie Balch, Alan P. Howell, Christine A. Reilly, Ernest Smith, Terrence Lee Fisher, Maurice Zauderer · 2022 · Figshare
- COUNTERING AGE-ASSOCIATED ALTERATIONS IN OLIGODENDROCYTE-DERIVED EXTRACELLULAR MATRIX REJUVENATES COGNITIONAmber R. Philp, L. Remesal, Karishma J. B. Pratt, Jason C. Maynard, Shanan Sahota, Turan Aghayev, Gregor Bieri, Rebecca Chu, Gabriel Avillion, Juliana Sucharov et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Disruption of the Brain-Spleen Axis Impairs Monocyte-Microglia Communication and Accelerates Disease Progression in a Model of AmyloidosisTommaso Croese, Miguel Angel Abellanas, Hodaya Polonsky, Michal Arad, Javier María Peralta Ramos, Yuliya Androsova, Serena Riccitelli, Sedi Medina, Francesca Palmas, Romano Strobel et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Métalloprotéases matricielles et maladie d'Alzheimer : étude du rôle de MT1-MMP dans le métabolisme de l'APP/AßNathalie A. Py · 2014 · theses.fr (ABES)
- Etudes de trois métalloprotéases matricielles, MT1-MMP, MT5-MMP et MMP-12 dans l'amyloïdogenèse et les atteintes inflammatoires et vasculaires associées à la maladie d'AlzheimerAmandine Bonnet · 2017 · theses.fr (ABES)
- Métalloprotéases matricielles et maladie d'Alzheimer : étude des rôles de MT1- et MT5-MMP dans l'amyloïdogenèse et la neuro-inflammationJean‐Michel Paumier · 2018 · theses.fr (ABES)
- Characterizing the Cellular and Molecular Effects of Neural Androgen Receptor Invalidation in Male MiceNida Karameh · 2018 · theses.fr (ABES)
- Etude de la contribution de l'hormone adipocytaire leptine dans la pathogenèse du syndrome de RettYasmine Belaïdouni · 2022 · theses.fr (ABES)
- Dysfonctionnement des interneurones cholinergiques du striatum comme substrat neuronal dans les troubles du spectre autistique en lien avec la délétion du gène Tshz3Jordan Molitor · 2022 · theses.fr (ABES)
- Thérapies du cancer de nouvelle génération et fonctions cognitives : Nouveaux concepts, nouveaux mécanismes, biomarqueurs originaux.Nicola Coppola · 2023 · theses.fr (ABES)
- FKBP51 inhibition by SAFit2 modulates tau pathology and cognitive deficits in PS19 miceAndrea Contreras-Marciales, Daniela Mezquite-Garcia, Laura A. Verdina, Ahmed Elnahrawy, Tiara Wolf, Jennifer Guergues, Priyanshi Parikh, Elle R. Hunter, Diana Hernandez Acosta, Stanley M. Stevens et al. · 2026 · Alzheimer s Research & Therapy
- Tau Transgenic MiceNatalie G. Horgan, Emma N. Poston, Jessica S. Fortin, David Morgan · 2026 · Neuromethods
- BindingDB Entry 50042662: Synthesis of quinoline derivatives: discovery of a potent and selective phosphodiesterase 5 inhibitor for the treatment of Alzheimer's disease.BindingDB · 2013 · UC San Diego
- BindingDB Entry 50000164: Identification of a Novel 1,2,3,4-Tetrahydrobenzo[b][1,6]naphthyridine Analogue as a Potent Phosphodiesterase 5 Inhibitor with Improved Aqueous Solubility for the Treatment of Alzheimer's Disease.BindingDB · 2019 · UC San Diego