Multimodal profiling of single-cell morphology, electrophysiology, and gene expression using Patch-seq

Cadwell, Cathryn R, Scala, Federico, Li, Shuang, Livrizzi, Giulia, Shen, Shan, Sandberg, Rickard, Jiang, Xiaolong, Tolias, Andreas S·2017·Nature Protocols

Cited by (147)

Items 101–147 of 147

  1. Somatostatin-Expressing Neurons in the Ventral Tegmental Area Innervate Specific Forebrain Regions and Are Involved in Stress Response
    Elina I. Nagaeva, Annika Schäfer, Anni-Maija Linden, Lauri V. Elsilä, Maria Ryazantseva, Juzoh Umemori, Ksenia Egorova, Esa R. Korpi · 2023 · eNeuro
  2. Single cell transcriptome sequencing of inspiratory neurons of the preBötzinger complex in neonatal mice
    Caroline K. David, Yae K. Sugimura, Prajkta S. Kallurkar, Maria Cristina D. Picardo, Margaret S. Saha, Gregory D. Smith, Christopher A. Del Negro · 2022 · Scientific Data
  3. Accurate and Automatic Extraction of Cell Self-Rotation Speed in an ODEP Field Using an Area Change Algorithm
    Haiyang Wu, Dan Dang, Xieliu Yang, Junhai Wang, Qi Ruolong, Wenguang Yang, Wenfeng Liang · 2022 · Micromachines
  4. Identification of TPBG-Expressing Amacrine Cells in DAT-tdTomato Mouse
    Wanjing Huang, Qiang Xu, Feng Liu, Jing Su, Dongchang Xiao, Lei Tang, Zhao-Zhe Hao, Ruifeng Liu, Kangjian Xiang, Yalan Bi et al. · 2022 · Investigative Ophthalmology & Visual Science
  5. Robotic Fast Patch Clamp in Brain Slices Based on Stepwise Micropipette Navigation and Gigaseal Formation Control
    Jinyu Qiu, Qili Zhao, Ruimin Li, Yuzhu Liu, Biting Ma, Xin Jie Zhao · 2025 · Sensors
  6. Single‐Cell Transcriptomic Analysis
    Zhihong Zheng, Enguo Chen, Weiguo Lü, Gary Charles Mouradian, Matthew Robert Hodges, Mingyu Liang, Pengyuan Liu, Yan Lü · 2020 · Comprehensive physiology
  7. Neuromodulation of Hippocampal Cells and Circuits
    J. Josh Lawrence, Stuart Cobb · 2018 · Springer series in computational neuroscience
  8. Multiomics Integration at Single-Cell Resolution Using Bayesian Networks: A Case Study in Hepatocellular Carcinoma
    Muntadher Jihad, İdil Yet · 2023 · OMICS A Journal of Integrative Biology
  9. Molecular logic for cellular specializations that initiate the auditory parallel processing pathways
    Junzhan Jing, Ming Hu, Tenzin Ngodup, Qianqian Ma, Shu-Ning Natalie Lau, M. Cecilia Ljungberg, Matthew J. McGinley, Laurence O. Trussell, Xiaolong Jiang · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  10. Protocol for mapping cell lineage and cell-type identity of clonally-related cells in situ using MADM-CloneSeq
    Giselle Cheung, Florian M. Pauler, Peter Koppensteiner, Simon Hippenmeyer · 2024 · STAR Protocols
  11. LINEAR AND NONLINEAR BEHAVIORS OF THE PHOTORECEPTOR COUPLED NETWORK
    Ji‐Jie Pang, Xiaolong Jiang, Samuel Miao-Sin Wu · 2024 · Journal of Neuroscience
  12. A Guide to Understanding “State-of-the-Art” Basic Research Techniques in Anesthesiology
    Detlef Obal, Shaogen Wu, Andrew R. McKinstry-Wu, Vivianne L. Tawfik · 2020 · Anesthesia & Analgesia
  13. Correlation Analysis of Molecularly-Defined Cortical Interneuron Populations with Morpho-Electric Properties in Layer V of Mouse Neocortex
    Jun-Wei Cao, Xiaoyi Mao, Liang Zhu, Zhishuo Zhou, Shao-Na Jiang, Lin‐Yun Liu, Shuqing Zhang, Yinghui Fu, Wendong Xu, Yong‐Chun Yu · 2022 · Neuroscience Bulletin
  14. Sparse bottleneck neural networks for exploratory non-linear visualization of Patch-seq data
    Yves Bernaerts, Philipp Berens, Dmitry Kobak · 2020 · arXiv (Cornell University)
  15. An atlas of primate insular cortex reveals a signal-processing strategy in von Economo neurons
    Rui-Feng Liu, Mengyao Huang, Yuhui Shen, Mingting Shao, Junzhan Jing, N W Xu, Lei Tang, B Q Liu, Jianming Shi, F N Chen et al. · 2026 · Nature Cell Biology
  16. Circuit-selective cell-autonomous regulation of inhibition in pyramidal neurons by Ste20-like kinase
    Pedro Royero, Anne Quatraccioni, Rieke Fruengel, Mariella Hurtado Silva, Arco Bast, Thomas Ulas, Marc Beyer, Thoralf Opitz, Joachim Ludwig Schultze, Mark Evan Graham et al. · 2022 · Cell Reports
  17. Targeted single cell expression profiling identifies integrators of sleep and metabolic state
    Meng-Fu Maxwell Shih, Jiwei Zhang, Elizabeth Brown, Josh Dubnau, Alex C. Keene · 2025 · G3 Genes Genomes Genetics
  18. Preparation of acute midbrain slices containing the superior colliculus and periaqueductal Gray for patch-clamp recordings
    Oriol Pavón Arocas, Tiago Branco · 2022 · PLoS ONE
  19. Riding brain “waves” to identify human memory genes
    H. C. Moore, Bradley Charles Lega, Geneviève Konopka · 2022 · Current Opinion in Cell Biology
  20. Identification of functional immune and neuronal tumour cells in glioma
    Rachel Naomi Curry, Malcolm F. McDonald, Qianqian Ma, Jochen F. Meyer, Isamu Aiba, Brittney Lozzi, Alexis Cervantes, Yeunjung Ko, Estefania Luna-Figueroa, Dong‐Joo Choi et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  21. In situ Patch-seq analysis of microglia reveals a lack of stress genes as found in FACS-isolated microglia
    Olga Bakina, Thomas Conrad, Nina Mitic, Ramon Oliveira Vidal, Tessa Obrusnik, Somesh Sai, Christiané Nolte, Marcus Semtner, Helmut Kettenmann · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  22. 2P-NucTag: on-demand phototagging for molecular analysis of functionally identified cortical neurons
    Jingcheng Shi, Boaz Nutkovich, Dahlia Kushinsky, Bovey Y. Rao, Stephanie A. Herrlinger, Emmanouil Tsivourakis, Tiberiu S. Mihaila, Margaret E. Conde Paredes, Katayun Cohen-Kashi Malina, Cliodhna K. O’Toole et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  23. Machine Vision Based Method for Measuring Single-Cell Biophysical Properties Using Dielectrophoresis Mobility
    Shengjie Chen, Zhizhong Zhang, Rong Zhu · 2021 · International Conference on Solid-State Sensors, Actuators and Microsystems
  24. Genetics meets function in sodium channel-related pain disorders
    Jannis Körner, Natja Haag, Ingo Kurth, Angelika Lampert · 2022 · e-Neuroforum
  25. Central Channelopathies in Obesity
    Athena Hsu Li, Yi‐Ying Kuo, Shi‐Bing Yang, Pei‐Chun Chen · 2024 · Journal of physiological investigation.
  26. Touch comes of Age - Maturational Plasticity in Somatosensory Mechanosensation
    Michel, Niklas · 2020
  27. A critical assessment of single-cell transcriptomes sampled following patch-clamp electrophysiology
    Shreejoy J. Tripathy, Lilah Toker, Claire Bomkamp, Burak Ogan Mancarci, Manuel Belmadani, Paul Pavlidis · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  28. Preclinical validation of endocannabinoid system drug targets for the treatment of Dravet syndrome
    Dilara Bahceci · 2020 · The Sydney eScholarship Repository (The University of Sydney)
  29. Spezielle Anwendungen
    Fabian Christoph Roth, Markus Numberger, Andreas Draguhn · 2023 · Springer eBooks
  30. Single Cell Morphology and Dynamic Signal Analysis Based on U-Net and DeepCell
    Rongkun Zhou · 2023 · IEEE International Conference on Image Processing and Computer Applications (ICIPCA)
  31. The Application of Single-Cell Omics Technologies in Neuroscientific Research
    Jiayao Zhou · 2024 · Genomics and Applied Biology
  32. Brain cell types and distribution
    Roxana N. Kooijmans · 2024 · Elsevier eBooks
  33. High-Quality Cell Capture Reveals Transcriptomic Changes After Single-Axon Injury of Mauthner Cells
    Zheng Song, Lin Zhu, Yueru Shen, Huaitong Yao, Yuan Cai, Lingyu Shi, Xinghan Chen, Along Han, Zi-Ang Zhao, Kun Qu et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  34. Special Applications
    Fabian Christoph Roth, Markus Numberger, Andreas Draguhn · 2025 · Springer eBooks
  35. Linking ion channel gene expression to neuronal firing patterns through a statistical-biophysical model
    Wanjing Huang, Qiang Xu, Sheng Liu · 2025 · Patterns
  36. Robotic Precise Patch Clamp Measurement Method Based on a Tight and Stable Gigaseal
    Jinyu Qiu, Bingxin Li, Ruimin Li, Yuzhu Liu, Xin Jie Zhao, Qili Zhao · 2025 · IEEE Transactions on Instrumentation and Measurement
  37. Additional file 1 of DANCE: a deep learning library and benchmark platform for single-cell analysis
    Ding, Jiayuan, Liu, Renming, Hongzhi Wen, Wenzhuo Tang, Zhaoheng Li, Julian Venegas, Runze Su, Dylan Molho, Jin, Wei, Yixin Wang et al. · 2024 · Figshare
  38. Additional file 4 of DANCE: a deep learning library and benchmark platform for single-cell analysis
    Ding, Jiayuan, Liu, Renming, Hongzhi Wen, Wenzhuo Tang, Zhaoheng Li, Julian Venegas, Runze Su, Dylan Molho, Jin, Wei, Yixin Wang et al. · 2024 · Figshare
  39. Additional file 2 of DANCE: a deep learning library and benchmark platform for single-cell analysis
    Ding, Jiayuan, Liu, Renming, Hongzhi Wen, Wenzhuo Tang, Zhaoheng Li, Julian Venegas, Runze Su, Dylan Molho, Jin, Wei, Yixin Wang et al. · 2024 · Figshare
  40. Additional file 3 of DANCE: a deep learning library and benchmark platform for single-cell analysis
    Ding, Jiayuan, Liu, Renming, Hongzhi Wen, Wenzhuo Tang, Zhaoheng Li, Julian Venegas, Runze Su, Dylan Molho, Jin, Wei, Yixin Wang et al. · 2024 · Figshare
  41. Additional file 5 of DANCE: a deep learning library and benchmark platform for single-cell analysis
    Ding, Jiayuan, Liu, Renming, Hongzhi Wen, Wenzhuo Tang, Zhaoheng Li, Julian Venegas, Runze Su, Dylan Molho, Jin, Wei, Yixin Wang et al. · 2024 · Figshare
  42. Additional file 6 of DANCE: a deep learning library and benchmark platform for single-cell analysis
    Ding, Jiayuan, Liu, Renming, Hongzhi Wen, Wenzhuo Tang, Zhaoheng Li, Julian Venegas, Runze Su, Dylan Molho, Jin, Wei, Yixin Wang et al. · 2024 · Figshare
  43. 2P-NucTag: On-demand phototagging for molecular analysis of functionally identified cortical neurons
    Jingcheng Shi, Boaz Nutkovich, Dahlia Kushinsky, Bovey Y. Rao, Stephanie A. Herrlinger, Emmanouil Tsivourakis, Tiberiu S. Mihaila, Margaret E. Conde Paredes, Katayun Cohen-Kashi Malina, Cliodhna K. O’Toole et al. · 2026 · Neuron
  44. Transistors Electrochimiques Organiques (OECTs) : nouveaux capteurs pour l’analyse de l’activité électrique des micro-organes pancréatiques
    Myriam Abarkan · 2021 · theses.fr (ABES)
  45. A vast temporal continuum for sensory processing arises from a nontopographic cellular multilevel gradient
    Kathrin D. Wicke, Nikolaos Kladisios, Kathrin Kattler‐Lackes, Felix Felmy · 2026 · Proceedings of the National Academy of Sciences
  46. DuBois-Reymond prize lecture 2024: Multi-neuron patch-clamp to uncover the neuronal and synaptic physiology in the human neocortex
    Yangfan Peng, Franz Xaver Mittermaier · 2026 · Pflügers Archiv - European Journal of Physiology
  47. Robotic Cell Contents Extraction in Biological Tissues Based on Cell Membrane Capacitance Variation
    Tairan Hu, Ruimin Li, Yuzhu Liu, Biting Ma, Jinyu Qiu, Weicheng Wang, Lulu Wang, Xin Jie Zhao, Qili Zhao · 2026 · IEEE Robotics and Automation Letters