Transcribing patterns of resistance
Integrity signals
Registry
Cites
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Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Exosomes engineered to deliver siRNAs that downregulate mutant KRAS, known as iExosomes, are under clinical investigation for KRASG12D-mutant PDAC.
“Exosomes are natural nanoparticles and have been engineered to deliver specific siRNAs to downregulate production of mutant KRAS (known as iExosomes) and are under clinical investigation for the treatment of KRASG12D-mutant PDAC203,204 (NCT03608631; Supplementary Table 1).”
From The current state of the art and future trends in RAS-targeted cancer therapies (2022) · cites this paper as [203]
Cites
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance
Shaffer, S. M., Dunagin, M. C., Torborg, S. R., Torre, E. A., Emert, B., Krepler, C., Beqiri, M., Sproesser, K., Brafford, P. A., Xiao, M., et al. (2017) · Nature · doi:10.1038/nature22794 · Cited by 1,218 · see citing works
Flagged first, then by citations
- Authors
- Seton-Rogers, S.
- Corresponding author
- Seton-Rogers, Sarah
- ORCID
- Seton-Rogers, Sarah
- Venue
- Nature Reviews Cancer
- Published
- 2017-07-25
- Volume
- 17
- Issue
- 8
- Pages
- 452-453
- ISSN
- 1474-175X (ISSN-L)
- 1474-1768
- OpenAlex
- W2738938999
- Cited by
- 2
- References
- 1
- Citations by year
- 2026: 1 · 2022: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature reviews. Cancer (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Oncology › Cancer Cells and Metastasis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Melanoma and MAPK Pathways
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer Genomics and Diagnostics
- Keywords
- melanoma, drug resistance, transcriptional variability, single-cell analysis, non-genetic resistance, resistance prediction
- MeSH terms
- Humans, Transcription, Genetic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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