DNA repair pathways as targets for cancer therapy
Helleday, Thomas, Petermann, Eva, Lundin, Cecilia, Hodgson, Ben, Sharma, Ricky A.·2008·Nature Reviews Cancer
DOI 10.1038/nrc2342
Cites (229)
Items 201–229 of 229
- Roles of SGS1, MUS81, and RAD51 in the repair of lagging-strand replication defects in Saccharomyces cerevisiaeMiki Ii, Steven J. Brill · 2005 · Current Genetics
- Characterization of the Repeat-Tract Instability and Mutator Phenotypes Conferred by a Tn3 Insertion in RFC1, the Large Subunit of the Yeast Clamp LoaderYali Xie, Christopher M. Counter, Eric Alani · 1999 · Genetics
- Mgs1 and Rad18/Rad5/Mms2 are required for survival of Saccharomyces cerevisiae mutants with novel temperature/cold sensitive alleles of the DNA polymerase delta subunit, Pol31.Niloofar Davoodi Vijeh Motlagh, M. Seki, Dana Branzei, T. Enomoto · 2006 · DNA Repair
- Modulation of nitrosourea resistance in human colon cancer by O6-methylguanineStanton L. Gerson, Nathan A. Berger, Cheryl Arce · 1992 · Biochemical Pharmacology
- A Dbf4p BRCA1 C-Terminal-Like Domain Required for the Response to Replication Fork Arrest in Budding YeastCarrie Gabrielse, Charles T. Miller, Kristopher H. McConnell, Aaron D. DeWard, Catherine A. Fox, Michael Weinreich · 2006 · Genetics
- Topoisomerase I-Dependent Viability Loss in Saccharomyces cerevisiae Mutants Defective in Both SUMO Conjugation and DNA RepairXiaole L. Chen, Hannah R. Silver, Ling Xiong · 2007 · Genetics
- Diminished S-Phase Cyclin-Dependent Kinase Function Elicits Vital Rad53-Dependent Checkpoint Responses in Saccharomyces cerevisiaeDaniel G. Gibson, Jennifer G. Aparicio, Fangfang Hu, Oscar M. Aparicio · 2004 · Molecular and Cellular Biology
- A New Saccharomyces cerevisiae Strain with a Mutant Smt3-Deconjugating Ulp1 Protein Is Affected in DNA Replication and Requires Srs2 and Homologous Recombination for Its ViabilityChristine Soustelle, Laurence Vernis, Karine Fréon, Anne Reynaud-Angelin, Roland Chanet, Francis Fabre, Martine Heude · 2004 · Molecular and Cellular Biology
- The therapeutic potential ofO6-alkylguanine DNA alkyltransferase inhibitorsOmar A Khan, Mark Ross Middleton · 2007 · Expert Opinion on Investigational Drugs
- STM1, a gene which encodes a guanine quadruplex binding protein, interacts with CDC13 in Saccharomyces cerevisiaeNaoyuki Hayashi, Seishi Murakami · 2002 · Molecular Genetics and Genomics
- Genomic Instability in CancerSara Rockwell, Jianling Yuan, Shani Peretz · 2001 · Novartis Foundation symposium
- Analysis of Conditional Mutations in the Saccharomyces cerevisiae MLH1 Gene in Mismatch Repair and in Meiotic Crossing OverJuan Lucas Argueso, Daniel L. Smith, James Yi, Marc Waase, Sumeet Sarin, Eric Alani · 2002 · Genetics
- Molecular cloning and characterization of a mammalian excision repair gene that partially restores UV resistance to xeroderma pigmentosum complementation group D cells.Janet E. Arrand, Neil M. Bone, Robert T. Johnson · 1989 · Proceedings of the National Academy of Sciences
- Coordinated functions of WSS1, PSY2 and TOF1 in the DNA damage responseBryan M. O’Neill · 2004 · Nucleic Acids Research
- The Rad1-Rad10 Complex Promotes the Production of Gross Chromosomal Rearrangements From Spontaneous DNA Damage in Saccharomyces cerevisiaeJi‐Young Hwang, Stephanie N. Smith, Kyungjae Myung · 2005 · Genetics
- Functional and physical interaction between Sgs1 and Top3 and Sgs1-independent function of Top3 in DNA recombination repair.Ryoko Onodera, Masayuki Seki, Ayako Ui · 2002 · Genes & Genetic Systems
- Sudden Telomere Lengthening Triggers a Rad53-dependent Checkpoint inSaccharomyces cerevisiaeValeria Viscardi, Enrico Baroni, Michele Romano, Giovanna Lucchini, Maria Pia Longhese · 2003 · Molecular Biology of the Cell
- Regulation of homologous integration in yeast by the DNA repair proteins Ku70 and RecQYoshimasa Yamana, Toshinari Maeda, Hiroyuki Ohba · 2005 · Molecular Genetics and Genomics
- Xeroderma pigmentosum complementation group F in a non-Japanese patientPaul G. Norris, John L.M. Hawk, J Avery, Francesco Giannelli · 1988 · Journal of the American Academy of Dermatology
- Disparate contributions of the Fanconi anemia pathway and homologous recombination in preventing spontaneous mutagenesisJohn M. Hinz, Peter B. Nham, Salustra S. Urbin, Irene M. Jones, Larry H. Thompson · 2007 · Nucleic Acids Research
- Distinct roles of DNA polymerases δ and ε at the replication fork in Xenopus egg extracts智行 福居 · 2004
- Participation of poly(ADP-robose) polymerase in the drug sensitivity in human lung cancer cell linesSachiyo Kubo, Mitsuko Matsutani, Kazuhiko Nakagawa · 1992 · Journal of Cancer Research and Clinical Oncology
- Abrogation of the Chk1-Pds1 Checkpoint Leads to Tolerance of Persistent Single-Strand Breaks in Saccharomyces cerevisiaeAnandi S. Karumbati, Thomas E. Wilson · 2005 · Genetics
- A mutation in yeast Tel1p that causes differential effects on the DNA damage checkpoint and telomere maintenanceMikhail Chakhparonian, David Faucher, Raymund J. Wellinger · 2005 · Current Genetics
- Strategies for Cloning Mammalian DNA Repair GenesLarry H. Thompson · 2003 · Humana Press eBooks
- Effect of Hypoxia on DNA Synthesis in the Bone Marrow and Spleen of the RatWALTER A. RAMBACH, John A. Cooper, Howard L. Alt · 1954 · Science
- Use of Yeast for Detection of Endogenous Abasic Lesions, Their Source, and Their RepairSerge Boiteux, Marie Guillet · 2006 · Methods in enzymology on CD-ROM/Methods in enzymology
- Phase I Trial of Intravenous Thymidine and Carboplatin in Patients With Advanced CancerH. Ian Robins, Kendra D. Tutsch, Doerthe M. Katschinski et al. · 1999 · Journal of Clinical Oncology
- Alterations in DNA repair and telomere maintenance mechanism affect response to porphyrins in yeast.Elżbieta Izbicka, Larry D. Barnes, Angela K. Robinson · 2001 · PubMed