The DOI matches its Crossref record; 220 of the 220 references it cites were found in a registry or an index.
Tailoring to RB: tumour suppressor status and therapeutic response
Open accessAbstract
The retinoblastoma tumour suppressor (RB) is a crucial regulator of cell-cycle progression that is invoked in response to a myriad of anti-mitogenic signals. It has been hypothesized that perturbations of the RB pathway confer a synonymous proliferative advantage to tumour cells; however, recent findings demonstrate context-specific outcomes associated with such lesions. Particularly, loss of RB function is associated with differential response to wide-ranging therapeutic agents. Thus, the status of this tumour suppressor may be particularly informative in directing treatment regimens.
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Cites
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Cited by
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Metadata
- Authors
- Knudsen, E. S., & Knudsen, K. E.
- Venue
- Nature Reviews Cancer
- Published
- 2008-08-07
- Volume
- 8
- Issue
- 9
- Pages
- 714-724
- ISSN
- 1474-175X (ISSN-L)
- 1474-1768
- OpenAlex
- W2079941948
- Cited by
- 344
- References
- 220
- FWCI
- 1.07
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Knudsen, E. S., & Knudsen, K. E. (2008). Tailoring to RB: tumour suppressor status and therapeutic response. Nature Reviews Cancer. https://doi.org/10.1038/nrc2401
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
