The DOI matches its Crossref record; 178 of the 178 references it cites were found in a registry or an index.
Basal cell carcinomas: attack of the hedgehog
Open accessAbstract
Basal cell carcinomas (BCCs) were essentially a molecular 'black box' until some 12 years ago, when identification of a genetic flaw in a rare subset of patients who have a great propensity to develop BCCs pointed to aberrant Hedgehog signalling as the pivotal defect leading to formation of these tumours. This discovery has facilitated a remarkable increase in our understanding of BCC carcinogenesis and has highlighted the carcinogenic role of this developmental pathway when aberrantly activated in adulthood. Importantly, a phase 1 first-in-human trial of a Hedgehog inhibitor has shown real progress in halting and even reversing the growth of these tumours.
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Cites
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Integrated analysis of multimodal single-cell data
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The Malassezia Genus in Skin and Systemic Diseases
Gaitanis, G., Magiatis, P., Hantschke, M., Bassukas, I. D., & Velegraki, A. (2012) · Clinical Microbiology Reviews · doi:10.1128/cmr.00021-11 · Cited by 642
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di Masi, A., Leboffe, L., De Marinis, E., Pagano, F., Cicconi, L., Rochette-Egly, C., Lo-Coco, F., Ascenzi, P., & Nervi, C. (2015) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2014.12.003 · Cited by 403
Identification of the cell lineage at the origin of basal cell carcinoma
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Metadata
- Authors
- Epstein, E. H.
- Venue
- Nature Reviews Cancer
- Published
- 2008-10
- Volume
- 8
- Issue
- 10
- Pages
- 743-754
- ISSN
- 1474-175X (ISSN-L)
- 1474-1768
- OpenAlex
- W1990453562
- Cited by
- 834
- References
- 178
- FWCI
- 2.36
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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