The DOI matches its Crossref record; 117 of the 117 references it cites were found in a registry or an index.
Normal tissue reactions to radiotherapy: towards tailoring treatment dose by genotype
Open accessAbstract
A key challenge in radiotherapy is to maximize radiation doses to cancer cells while minimizing damage to surrounding healthy tissue. As severe toxicity in a minority of patients limits the doses that can be safely given to the majority, there is interest in developing a test to measure an individual's radiosensitivity before treatment. Variation in sensitivity to radiation is an inherited genetic trait and recent progress in genotyping raises the possibility of genome-wide studies to characterize genetic profiles that predict patient response to radiotherapy.
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Cites
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
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Genetics of Food Intake Self-Regulation in Childhood: Literature Review and Research Opportunities
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Radiotherapy plus Cetuximab for Squamous-Cell Carcinoma of the Head and Neck
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Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
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Self-citation
Cited by
Graves, D. B. (2012) · Journal of Physics D: Applied Physics · doi:10.1088/0022-3727/45/26/263001 · Cited by 1,518
Ionizing Radiation-Induced DNA Damage, Response, and Repair
Santivasi, W. L., & Xia, F. (2014) · Antioxidants & Redox Signaling · doi:10.1089/ars.2013.5668 · Cited by 593
A genome-based model for adjusting radiotherapy dose (GARD): a retrospective, cohort-based study
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Cancer risks associated with external radiation from diagnostic imaging procedures
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Bourgeois-Daigneault, M.-C., Roy, D. G., Aitken, A. S., El Sayes, N., Martin, N. T., Varette, O., Falls, T., St-Germain, L. E., Pelin, A., Lichty, B. D., et al. (2018) · Science Translational Medicine · doi:10.1126/scitranslmed.aao1641 · Cited by 293
Metadata
- Authors
- Barnett, G. C., West, C. M. L., Dunning, A. M., Elliott, R. M., Coles, C. E., Pharoah, P. D. P., & Burnet, N. G.
- Venue
- Nature Reviews Cancer
- Published
- 2009-01-16
- Volume
- 9
- Issue
- 2
- Pages
- 134-142
- ISSN
- 1474-175X (ISSN-L)
- 1474-1768
- OpenAlex
- W2016899305
- Cited by
- 771
- References
- 117
- FWCI
- 3.88
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Normal tissue reactions to radiotherapy: towards tailoring treatment dose by genotype. https://app.cochat.ai/papers/10.1038/nrc2587
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- Barnett, G. C., West, C. M. L., Dunning, A. M., Elliott, R. M., Coles, C. E., Pharoah, P. D. P., & Burnet, N. G. (2009). Normal tissue reactions to radiotherapy: towards tailoring treatment dose by genotype. Nature Reviews Cancer. https://doi.org/10.1038/nrc2587
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
