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Cited by 1,942

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

Non-small-cell lung cancers: a heterogeneous set of diseases

Open access
Chen, Zhao, Fillmore, Christine M., Hammerman, Peter S., Kim, Carla F., Wong, Kwok-Kin·2014·Nature Reviews Cancer

Abstract

Non-small-cell lung cancers (NSCLCs), the most common lung cancers, are known to have diverse pathological features. During the past decade, in-depth analyses of lung cancer genomes and signalling pathways have further defined NSCLCs as a group of distinct diseases with genetic and cellular heterogeneity. Consequently, an impressive list of potential therapeutic targets was unveiled, drastically altering the clinical evaluation and treatment of patients. Many targeted therapies have been developed with compelling clinical proofs of concept; however, treatment responses are typically short-lived. Further studies of the tumour microenvironment have uncovered new possible avenues to control this deadly disease, including immunotherapy.

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Crossref · 10.1038/nrc3775

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Metadata

Authors
Chen, Z., Fillmore, C. M., Hammerman, P. S., Kim, C. F., & Wong, K.-K.
Venue
Nature Reviews Cancer
Published
2014-07-24
Volume
14
Issue
8
Pages
535-546
ISSN
  • 1474-175X (ISSN-L)
  • 1474-1768
OpenAlex
W1989734503
Cited by
1,942
References
45
FWCI
16.42
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Non-small-cell lung cancers: a heterogeneous set of diseases. https://app.cochat.ai/papers/10.1038/nrc3775
The paper
Chen, Z., Fillmore, C. M., Hammerman, P. S., Kim, C. F., & Wong, K.-K. (2014). Non-small-cell lung cancers: a heterogeneous set of diseases. Nature Reviews Cancer. https://doi.org/10.1038/nrc3775

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.