The Fanconi anaemia/BRCA pathway

D'Andrea, Alan D., Grompe, Markus·2003·Nature Reviews Cancer

DOI 10.1038/nrc970

Cited by (823)

Items 201–300 of 823

The Fanconi anemia/BRCA pathway: A coordinator of cross-link repair
Kanchan D. Mirchandani, Alan D. D’Andrea · 2006 · Experimental Cell Research
Homology-directed Fanconi anemia pathway cross-link repair is dependent on DNA replication
Koji Nakanishi, Francesca Cavallo, Loı̈c Perrouault, Carine Giovannangeli, Mary Ellen Moynahan, Marco Barchi, Erika Brunet, Maria Jasin · 2011 · Nature Structural & Molecular Biology
Oxidant Hypersensitivity of Fanconi Anemia Type C-deficient Cells Is Dependent on a Redox-regulated Apoptotic Pathway
Mohammad Reza Saadatzadeh, Khadijeh Bijangi‐Vishehsaraei, Ping Hong, Heidi Bergmann, Laura S. Haneline · 2004 · Journal of Biological Chemistry
Potential Application of Curcumin and Its Analogues in the Treatment Strategy of Patients with Primary Epithelial Ovarian Cancer
Katarzyna Maria Terlikowska, Anna Maria Witkowska, Małgorzata Elżbieta Zujko, Bożena Dobrzycka, Slawomir Jerzy Terlikowski · 2014 · International Journal of Molecular Sciences
Cdc7 kinase – A new target for drug development
Ronan T. Swords, Devalingam Mahalingam, Michael E O'Dwyer, Corrado Santocanale, Kevin R. Kelly, Jennifer S. Carew, Francis Joseph Giles · 2009 · European Journal of Cancer
Fanconi Anemia: A DNA repair disorder characterized by accelerated decline of the hematopoietic stem cell compartment and other features of aging
Robert M. Brosh, Marina A. Bellani, Yie Liu, Michael M. Seidman · 2016 · Ageing Research Reviews
The Fanconi anemia group A protein modulates homologous repair of DNA double-strand breaks in mammalian cells
Yun‐Gui Yang, Zdenko Herceg, Koji Nakanishi, Ilja Demuth, Colette Piccoli, Jocelyne Michelon, Gabriele Hildebrand, Maria Jasin, Martin Digweed, Zhao‐Qi Wang · 2005 · Carcinogenesis
DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer
Yunxiao Meng, Chi‐Wei Chen, Mingo M. H. Yung, Wei Sun, Jing Fang Sun, Zhuqing Li, Jing Li, Zongzhu Li, Wei Zhou, Stephanie S. Liu et al. · 2018 · Cancer Letters
An ATR- and BRCA1-Mediated Fanconi Anemia Pathway Is Required for Activating the G2/M Checkpoint and DNA Damage Repair upon Rereplication
Wenge Zhu, Anindya Dutta · 2006 · Molecular and Cellular Biology
BRCA1 Associates with Processive RNA Polymerase II
Susan A. Krum, Gustavo A. Miranda, Chenwei Lin, Timothy F. Lane · 2003 · Journal of Biological Chemistry
Insights into a Critical Role of the FOXO3a-FOXM1 Axis in DNA Damage Response and Genotoxic Drug Resistance
Gabriela Nestal de Moraes, Laura Bella, Stefania Zona, Matthew J. Burton, Eric W.‐F. Lam · 2016 · Current Drug Targets
Clinical management of BRCA1 and BRCA2 mutation carriers
Susan M. Domchek, Barbara Weber · 2006 · Oncogene
Neoadjuvant treatments in triple-negative breast cancer patients: where we are now and where we are going
Claudia Omarini, Giorgia Guaitoli, Stefania Pipitone, Luca I. Moscetti, Laura Cortesi, Stefano Cascinu, Federico Piacentini · 2018 · Cancer Management and Research
DNA Repair Gene Polymorphisms and Risk of Pancreatic Cancer
Donghui Li, Hideo Suzuki, Bing-Rong Liu, Jeffrey S. Morris, Jun Liu, Taro Okazaki, Yanan Li, Ping Chang, James L. Abbruzzese · 2009 · Clinical Cancer Research
Multiple TPR motifs characterize the Fanconi anemia FANCG protein
Eric Blom, Henri J. van de Vrugt, Yne de Vries, Johan P. de Winter, Fré Arwert, Hans Joenje · 2003 · DNA repair
Fanconi Anemia Pathway: Mechanisms of Breast Cancer Predisposition Development and Potential Therapeutic Targets
Can-Bin Fang, Hua-Tao Wu, Manli Zhang, Jing Liu, Guo‐Jun Zhang · 2020 · Frontiers in Cell and Developmental Biology
Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis
Younghoon Kee, Jung Min Kim, Alan D. D’Andrea · 2009 · Genes & Development
Fanconi anaemia proteins: Major roles in cell protection against oxidative damage
Giovanni Pagano, Hagop Youssoufian · 2003 · BioEssays
Evaluation of Fanconi Anemia genes in familial breast cancer predisposition.
Sheila Seal, Rita Barfoot, Hiran Jayatilake, Paula Smith, Anthony Renwick, Linda Bascombe, Lesley McGuffog, D. Gareth Evans, Diana Eccles, Douglas F. Easton et al. · 2003 · PubMed
Experimental approaches to the study of primordial germ cell lineage and proliferation
Massimo De Felici · 2004 · Human Reproduction Update
Lessons learned from DNA repair defective syndromes
Kai‐Martin Thoms, Christiane Kuschal, Steffen Emmert · 2007 · Experimental Dermatology
Direct DNA Binding Activity of the Fanconi Anemia D2 Protein
Woo-Hyun Park, Steven P. Margossian, Andrew A. Horwitz, Amanda M. Simons, Alan D. D’Andrea, Jeffrey D. Parvin · 2005 · Journal of Biological Chemistry
The interplay of Fanconi anemia proteins in the DNA damage response
XiaoZhe Wang, Alan D. D’Andrea · 2004 · DNA repair
Toll-Like Receptor 9 Regulates the Lung Macrophage Phenotype and Host Immunity in Murine Pneumonia Caused byLegionella pneumophila
Urvashi Bhan, Glenda Trujillo, Kenneth E. Lyn-Kew, Michael W. Newstead, Xianying Zeng, Cory M. Hogaboam, Arthur Μ. Krieg, Theodore J. Standiford · 2008 · Infection and Immunity
Resistance of hypoxic cells to ionizing radiation is influenced by homologous recombination status
Debbie Sprong, Hilde L. Janssen, Conchita Vens, Adrian C. Begg · 2005 · International Journal of Radiation Oncology*Biology*Physics
FANCF methylation contributes to chemoselectivity in ovarian cancer
Olufunmilayo Ibironke Olopade, Minjie Wei · 2003 · Cancer Cell
Molecular analysis of sister chromatid recombination in mammalian cells
Nadine Puget, Melodie L. Knowlton, Ralph Scully · 2004 · DNA repair
Genomic instability and radiation
John B. Little · 2003 · Journal of Radiological Protection
The yeast Snm1 protein is a DNA 5′-exonuclease
Xiaoroang Li, James Hejna, Robb E. Moses · 2004 · DNA repair
The ATM/p53/p21 Pathway Influences Cell Fate Decision between Apoptosis and Senescence in Reoxygenated Hematopoietic Progenitor Cells
Xiaoling Zhang, June Li, Daniel P. Sejas, Qishen Pang · 2005 · Journal of Biological Chemistry
Oxidative Stress/Damage Induces Multimerization and Interaction of Fanconi Anemia Proteins
Su-Jung Park, Samantha L. M. Ciccone, Brian D. Beck, Byounghoon Hwang, Brian W. Freie, D. Wade Clapp, Suk‐Hee Lee · 2004 · Journal of Biological Chemistry
Genetic predictors of taxane-induced neurotoxicity in a SWOG phase III intergroup adjuvant breast cancer treatment trial (S0221)
Lara E. Sucheston, Hua Zhao, Song Yao, Gary Zirpoli, Song Liu, William Eric Barlow, Halle C. F. Moore, George Thomas Budd, Dawn L. Hershman, Warren Davis et al. · 2011 · Breast Cancer Research and Treatment
The S phase checkpoint: When the crowd meets at the fork
Vanesa Gottifredi, Carol L. Prives · 2005 · Seminars in Cell and Developmental Biology
Downregulation of Fanconi Anemia Genes in Sporadic Head and Neck Squamous Cell Carcinoma
Volkert B. Wreesmann, Cherry L. Estilo, David W. Eisele, Bhuvanesh Singh, Steven J. Wang · 2007 · ORL
Monoubiquitylation in the Fanconi anemia DNA damage response pathway
Arno F. Alpi, Ketan J. Patel · 2009 · DNA repair
Breaking the DNA damage response to improve cervical cancer treatment
Hylke W. Wieringa, Ate G.J. van der Zee, Elisabeth G.E. de Vries, Marcel A.T.M. van Vugt · 2015 · Cancer Treatment Reviews
Bi‐allelic silencing of the Fanconi anaemia gene FANCF in acute myeloid leukaemia
Marc D. Tischkowitz, Najim Ameziane, Quinten Waisfisz, Johan P. de Winter, Richard Harris, Toshiyasu Taniguchi, Alan D. D’Andrea, Shirley Victoria Hodgson, Christopher George Mathew, Hans Joenje · 2003 · British Journal of Haematology
The role of the RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system
Kay F. Macleod · 2008 · Nature reviews. Cancer
The structure of the FANCM–MHF complex reveals physical features for functional assembly
Yuyong Tao, Changjiang Jin, Xu Li, Shali Qi, Lingluo Chu, Liwen Niu, Xuebiao Yao, Maikun Teng · 2012 · Nature Communications
CDYL1 fosters double-strand break-induced transcription silencing and promotes homology-directed repair
Enas R. Abu‐Zhayia, Samah W. Awwad, Bella M. Ben‐Oz, Hanan Khoury-Haddad, Nabieh Ayoub · 2017 · Journal of Molecular Cell Biology
The DNA double-strand break response pathway: becoming more BRCAish than ever
Nicholas S. Y. Ting, Wen‐Hwa Lee · 2004 · DNA repair
Ex vivo culture of Fancc-/- stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy
Xiaxin Li, Michelle M. Le Beau, Samantha L. M. Ciccone, Feng‐Chun Yang, Brian W. Freie, Chen Shi, Jin Yuan, Ping Hong, Attilio Orazi, Laura S. Haneline et al. · 2005 · Blood
The Fanconi anemia pathway: Repairing the link between DNA damage and squamous cell carcinoma
Lindsey E. Romick‐Rosendale, Vivian Wai Yan Lui, Jennifer Rubin Grandis, Susanne I. Wells · 2013 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
Current Approaches to Pancreatic Cancer Screening
Ankit Chhoda, Lingeng Lu, Barbara M. Clerkin, Harvey A. Risch, James J. Farrell · 2018 · American Journal Of Pathology
Dedicated to the core: Understanding the Fanconi anemia complex
Allan M. Gurtan, Alan D. D’Andrea · 2006 · DNA repair
DNA repair pathways and hereditary cancer susceptibility syndromes
Malinda L Spry · 2007 · Frontiers in bioscience
Distinct binding of BRCA2 BRC repeats to RAD51 generates differential DNA damage sensitivity
Gouri Chatterjee, Judit Jiménez-Sáinz, Thomas Presti, Tiffany Tuyen Minh Nguyen, Ryan B. Jensen · 2016 · Nucleic Acids Research
p97 Promotes a Conserved Mechanism of Helicase Unloading during DNA Cross-Link Repair
George Fullbright, Halley B. Rycenga, Jordon D. Gruber, David T. Long · 2016 · Molecular and Cellular Biology
Rad18-mediated Translesion Synthesis of Bulky DNA Adducts Is Coupled to Activation of the Fanconi Anemia DNA Repair Pathway
Ihn Young Song, Komaraiah Palle, Aditi U. Gurkar, Satoshi Tateishi, Gary M. Kupfer, Cyrus Vaziri · 2010 · Journal of Biological Chemistry
Targeted treatment of recurrent platinum-resistant ovarian cancer: current and emerging therapies
Mantia-Smaldone, Edwards, Anda Vlad · 2010 · Cancer Management and Research
Sub‐nuclear localization of Rad51 in response to DNA damage
Emil Mladenov, Boyka Anachkova, Irina R. Tsaneva · 2006 · Genes to Cells
New insights into the Fanconi anemia pathway from an isogenic FancG hamster CHO mutant
Robert S. Tebbs, John M. Hinz, Nazumi Alice Yamada, James B. Wilson, Edmund P. Salazar, Cynthia B. Thomas, Irene M. Jones, Nigel J. Jones, Larry H. Thompson · 2004 · DNA repair
Breast cancer prognostication and prediction in the postgenomic era
Per Eystein Lønning, Stian Knappskog, Vidar Staalesen, Ranjan Chrisanthar, JR Lillehaug · 2007 · Annals of Oncology
DNA Damage: From Chronic Inflammation to Age-Related Deterioration
Άννα Ιωαννίδου, Evi Goulielmaki, George A. Garinis · 2016 · Frontiers in Genetics
Survival of the fittest: in vivo selection and stem cell gene therapy
Tobias Neff, Brian C. Beard, Hans‐Peter Kiem · 2005 · Blood
The Fanconi anemia pathway and ubiquitin
Céline F. Jacquemont, Toshiyasu Taniguchi · 2007 · BMC Biochemistry
Epigenetic Drivers of Genetic Alterations
Minoru Toyota, Hiromu Suzuki · 2010 · Advances in genetics
Targeting abnormal DNA double strand break repair in cancer
Feyruz Virgilia Rassool, Alan E. Tomkinson · 2010 · Cellular and Molecular Life Sciences
Crosslinks and crosstalk
Mary A. Risinger, Joanna Louise Groden · 2004 · Cancer Cell
Increased Atherosclerotic Lesions in LDL Receptor Deficient Mice With Hematopoietic Nuclear Receptor Rev‐erbα Knock‐ Down
Hongling Ma, Wenbin Zhong, Yingliang Jiang, Coralie Fontaine, Shiqian Li, Jiangnan Fu, Vesa M. Olkkonen, Bart Staels, Daoguang Yan · 2013 · Journal of the American Heart Association
Heterozygosity for p53 (Trp53 +/−) Accelerates Epithelial Tumor Formation in Fanconi Anemia Complementation Group D2 (Fancd2) Knockout Mice
Scott Robert Houghtaling, Laura A. Granville, Yassmine M. N. Akkari, Yumi Torimaru, Susan B. Olson, Milton J. Finegold, Markus Grompe · 2005 · Cancer Research
Triamcinolone acetonide activates an anti-inflammatory and folate receptor–positive macrophage that prevents osteophytosis in vivo
M. Siebelt, Nicoline M. Korthagen, Wu Wei, Harald C. Groen, Yvonne M. Bastiaansen-Jenniskens, C. Müller, Jan Hendrik Waarsing, Marion de Jong, Harrie Weinans · 2015 · Arthritis Research & Therapy
FANCD2 and DNA Damage
Manoj K. Nepal, Raymond Che, Chi Ma, Jun Zhang, Peiwen Fei · 2017 · International Journal of Molecular Sciences
Fanconi anemia in Ashkenazi Jews
David Ivan Kutler, Arleen D. Auerbach · 2004 · Familial Cancer
Hypoxia-reoxygenation induces premature senescence in FA bone marrow hematopoietic cells
Xiaoling Zhang, June Li, Daniel P. Sejas, Qishen Pang · 2005 · Blood
Efficient Deletion of Normal Brca2-Deficient Intestinal Epithelium by Poly(ADP-Ribose) Polymerase Inhibition Models Potential Prophylactic Therapy
Trevor Hay, Helen Jenkins, Owen James Sansom, Niall M.B. Martin, Graeme C.M. Smith, Alan Richard Clarke · 2005 · Cancer Research
Fanconi Anemia Complementation Group FANCD2 Protein Serine 331 Phosphorylation Is Important for Fanconi Anemia Pathway Function and BRCA2 Interaction
Gang Zhi, James B. Wilson, Xiaoyong Chen, Diane S. Krause, Yuxuan Xiao, Nigel J. Jones, Gary M. Kupfer · 2009 · Cancer Research
Epigenetic Deregulation of DNA Repair and Its Potential for Therapy
Monika E. Hegi, Davide Sciuscio, Anastasia Murat, Marc Levivier, Roger Stupp · 2009 · Clinical Cancer Research
XRCC2 and XRCC3 Regulate the Balance between Short- and Long-Tract Gene Conversions between Sister Chromatids
Ganesh Nagaraju, Andrea J. Hartlerode, Amy Kwok, Gurushankar Chandramouly, Ralph Scully · 2009 · Molecular and Cellular Biology
Homozygous disruption of PDZD7 by reciprocal translocation in a consanguineous family: a new member of the Usher syndrome protein interactome causing congenital hearing impairment
Eberhard Schneider, Tina Märker, Angelika Daser, Gabriele Frey-Mahn, Vera Beyer, Ruxandra Farcas, Brigitte Schneider-Rätzke, Nicolai Kohlschmidt, Bärbel Grossmann, Katharina Bauß et al. · 2008 · Human Molecular Genetics
Fancd2 functions in a double strand break repair pathway that is distinct from non-homologous end joining
Scott Robert Houghtaling, Amy Hanlon Newell, Yassmine M. N. Akkari, Toshiyasu Taniguchi, Susan B. Olson, Markus Grompe · 2005 · Human Molecular Genetics
Targeted Disruption of FANCC and FANCG in Human Cancer Provides a Preclinical Model for Specific Therapeutic Options
Eike Gallmeier, Eric S. Calhoun, Carlo Rago, Jonathan Robert Brody, Steven Clark Cunningham, Tomáš Hucl, Myriam Gorospe, Manu Kohli, Christoph Lengauer C, Scott E. Kern · 2006 · Gastroenterology
CtBP1 Is Expressed in Melanoma and Represses the Transcription of p16INK4a and Brca1
Hui Deng, Jing Liu, Yu Deng, Gangwen Han, Yiqun G. Shellman, Steven E. Robinson, John J. Tentler, William Allen Robinson, David Albert Norris, Xiao‐Jing Wang et al. · 2013 · Journal of Investigative Dermatology
Replication Stress, Defective S-phase Checkpoint and Increased Death in Plk2-Deficient Human Cancer Cells
Elizabeth M. Matthew, Tim J. Yen, David T. Dicker, Jay F. Dorsey, Wensheng Yang, Arunasalam Navaraj, Wafik S. El‐Deiry · 2007 · Cell Cycle
Disruption of the Fanconi anemia/BRCA pathway in sporadic cancer
Alex Lyakhovich, Jordi Surrallés · 2005 · Cancer Letters
Death by Abl: A Matter of Location
Jiangyu Zhu, Jean Y. J. Wang · 2004 · Current topics in developmental biology/Current Topics in Developmental Biology
Improvement of spinal non-viral IL-10gene delivery by D-mannose as a transgene adjuvant to control chronic neuropathic pain
Ellen C. Dengler, Lauren A Alberti, Brandi N. Bowman, Audra A. Kerwin, Jenny L. Wilkerson, Daniel R Moezzi, Eugene Limanovich, James Alfred Wallace, Erin D. Milligan · 2014 · Journal of Neuroinflammation
Expression Signature Defined by FOXM1–CCNB1 Activation Predicts Disease Recurrence in Non–Muscle-Invasive Bladder Cancer
Seon‐Kyu Kim, Yun-Gil Roh, Kiejung Park, Tae‐Hong Kang, Wun‐Jae Kim, Ju‐Seog Lee, Sun-Hee Leem, In‐Sun Chu · 2014 · Clinical Cancer Research
Nucleophosmin Regulates Cell Cycle Progression and Stress Response in Hematopoietic Stem/Progenitor Cells
June Li, Daniel P. Sejas, Reena Rani, Tara Koretsky, Grover C. Bagby, Qishen Pang · 2006 · Journal of Biological Chemistry
Regulation of hematopoietic stem cell fate by the ubiquitin proteasome system
Kelly Moran-Crusio, Linsey B. Reavie, Iannis Aifantis · 2012 · Trends in Immunology
Regulation of stem cell function by protein ubiquitylation
Alexandros Strikoudis, María Guillamot, Iannis Aifantis · 2014 · EMBO Reports
Fanconi DNA repair pathway is required for survival and long‐term maintenance of neural progenitors
Karine Sii-Felice, Olivier Etienne, Françoise Hoffschir, Céline Mathieu, Lydia Riou, Vilma Barroca, Céline Haton, Fré Arwert, Pierre Fouchet, François Dominique Boussin et al. · 2008 · The EMBO Journal
Crosstalk between BRCA‐Fanconi anemia and mismatch repair pathways prevents MSH2‐dependent aberrant DNA damage responses
Min Peng, Jenny Xie, Anna J. Ucher, Janet Stavnezer, Sharon B. Cantor · 2014 · The EMBO Journal
Genes causing inherited cancer as beacons to identify the mechanisms of chemoresistance
Per Eystein Lønning · 2004 · Trends in Molecular Medicine
The FANC pathway and mitosis: A replication legacy
Valeria Naim, Filippo Rosselli · 2009 · Cell Cycle
Activation of DNA damage signaling
Mats E. Ljungman · 2005 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
The Fanconi Anemia Proteins Functionally Interact with the Protein Kinase Regulated by RNA (PKR)
Xiaoling Zhang, June Li, Daniel P. Sejas, Keaney R. Rathbun, Grover C. Bagby, Qishen Pang · 2004 · Journal of Biological Chemistry
Targeting DNA repair in breast cancer: A clinical and translational update
Eitan Amir, Boštjan Šeruga, Rosario Serrano, Alberto Ocaña · 2010 · Cancer Treatment Reviews
Phenylbutyrate interferes with the Fanconi anemia and BRCA pathway and sensitizes head and neck cancer cells to cisplatin
Kyunghee Burkitt, Mats E. Ljungman · 2008 · Molecular Cancer
Protective immunity to liver-stage malaria
Lauren E. Holz, Daniel Fernandez-Ruiz, W. Heath · 2016 · Clinical & Translational Immunology
FZD5 contributes to TNBC proliferation, DNA damage repair and stemness
Yu Sun, Zhuo Wang, Na Lei, Dan Feng Dong, Wei Wang, Chenghai Zhao · 2020 · Cell Death and Disease
DNA double-strand break repair and development
E R Phillips, Peter J. McKinnon · 2007 · Oncogene
Hypersensitivity of Brca1-deficient MEF to the DNA interstrand crosslinking agent mitomycin C is associated with defect in homologous recombination repair and aberrant S-phase arrest
Jeanho Yun, Qing Zhong, Jong‐Young Kwak, Wen‐Hwa Lee · 2005 · Oncogene
The WD40 Repeats of FANCL Are Required for Fanconi Anemia Core Complex Assembly
Allan M. Gurtan, Patricia Stuckert, Alan D. D’Andrea · 2006 · Journal of Biological Chemistry
αII-Spectrin interacts with five groups of functionally important proteins in the nucleus
Deepa Sridharan, Laura McMahon, M LAMBERT · 2006 · Cell Biology International
Mutation analysis of FANCD2, BRIP1/BACH1, LMO4 and SFN in familial breast cancer
Aaron Lewis, James M. Flanagan, Anna J. Marsh, Gulietta M. Pupo, Graham J. Mann, Amanda B. Spurdle, Geoffrey John Lindeman, Jane E. Visvader, Melissa A. Brown, Georgia Chenevix‐Trench · 2005 · Breast Cancer Research
Loss of expression of FANCD2 protein in sporadic and hereditary breast cancer
Petra van der Groep, Michael Hoelzel, Horst Buerger, Hans Joenje, Johan P. de Winter, P. J. van Diest · 2007 · Breast Cancer Research and Treatment
No formation of DNA double-strand breaks and no activation of recombination repair with UVA
Rizzo, Jennifer L., Dunn, Jessica, Rees, Adam, Rünger, Thomas M. · 2011 · Journal of Investigative Dermatology
Promoter hypermethylation of FANCF and outcome in advanced ovarian cancer
S.L. Lim, P Smith, Nelofer Syed, Corneel Coens, Helen H. Wong, Maria van der Burg, Piotr W. Szlosarek, Tim Crook, J A Green · 2008 · British Journal of Cancer
Mouse models of DNA double-strand break repair and neurological disease
Pierre‐Olivier Frappart, Peter J. McKinnon · 2008 · DNA repair