The Fanconi anaemia/BRCA pathway

D'Andrea, Alan D., Grompe, Markus·2003·Nature Reviews Cancer

Cited by (823)

Items 401–500 of 823

  1. The Fanconi Family Adds a Fraternal Twin
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  2. Nematode modulation of inflammatory bowel disease
    Rose Whelan, Susanne Hartmann, Sebastian Rausch · 2011 · PROTOPLASMA
  3. Finding the needle in the hay stack: Hematopoietic stem cells in Fanconi anemia
    Lars Müller, David A. Williams · 2009 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
  4. Overlooked FANCD2 variant encodes a promising, portent tumor suppressor, and alternative polyadenylation contributes to its expression
    Bing Han, Yihang Shen, Piyan Zhang, Jayabal Panneerselvam, Raymond Che, Jun Zhang, Herbert Yu, Peiwen Fei · 2017 · Oncotarget
  5. Molecular Biology of Oral Cavity Squamous Cell Carcinoma
    Michael Elliot Kupferman, Jeffrey N. Myers · 2006 · Otolaryngologic Clinics of North America
  6. A new nuclease member of the FAN club
    Huang, Min, D'Andrea, Alan D · 2010 · Nature Structural & Molecular Biology
  7. Co-opting the Fanconi Anemia Genomic Stability Pathway Enables Herpesvirus DNA Synthesis and Productive Growth
    Heidi Karttunen, Jeffrey N. Savas, Caleb C. McKinney, Yu-Hung Chen, John R. Yates, Veijo Hukkanen, Tony T. Huang, Ian Mohr · 2014 · Molecular Cell
  8. A computational model for classification of BRCA2 variants using mouse embryonic stem cell-based functional assays
    Kajal Biswas, Gary B. Lipton, Stacey Stauffer, Teresa L. Sullivan, Linda Cleveland, Eileen A. Southon, Susan W. Reid, Valentin Magidson, Edwin S. Iversen, Shyam K. Sharan · 2020 · npj Genomic Medicine
  9. Histone deacetylases as new therapy targets for platinum-resistant epithelial ovarian cancer
    Dmitri Pchejetski, Albandri Alfraidi, Keith A. Sacco, Heba A Alshaker, Aun Muhammad, Leonardo Monzon · 2015 · Journal of Cancer Research and Clinical Oncology
  10. Lower level of BRCA2 protein in heterozygous mutation carriers is correlated with an increase in DNA double strand breaks and an impaired DSB repair
    Katrin Arnold, Minkyoung Kim, Katrin Frerk, Lutz Edler, Larissa Savelyeva, Peter Schmezer, Ruprecht Wiedemeyer · 2006 · Cancer Letters
  11. Telomere dynamics in Fancg-deficient mouse and human cells
    Sonia Franco, Henri J. van de Vrugt, Piedad Fernández, Miguel Aracil, Fré Arwert, Marı́a A. Blasco · 2004 · Blood
  12. Human Mus81 and FANCB independently contribute to repair of DNA damage during replication
    Yuji Nomura, Noritaka Adachi, Hideki Koyama · 2007 · Genes to Cells
  13. UBE2W Interacts with FANCL and Regulates the Monoubiquitination of Fanconi Anemia Protein FANCD2
    Yingying Zhang, Xiaowei Zhou, Lixia Zhao, Chao Li, Heng-Qi Zhu, Long Xu, Liran Shan, Xiang Liao, Zekun Guo, Peitang Huang · 2011 · Molecules and Cells
  14. Rad18 is required for functional interactions between FANCD2, BRCA2, and Rad51 to repair DNA topoisomerase 1-poisons induced lesions and promote fork recovery
    Kaushlendra K. Tripathi, Chinnadurai Mani, David W Clark, Komaraiah Palle · 2016 · Oncotarget
  15. Evaluation of the methods to identify patients who may benefit from PARP inhibitor use
    Diana Gkeok Stzuan Lim, Joanne Yuen Yie Ngeow · 2016 · Endocrine Related Cancer
  16. Establishment and Characterization of a New Intrahepatic Cholangiocarcinoma Cell Line Resistant to Gemcitabine
    Chiara Varamo, Caterina Peraldo Neia, Paola Ostano, Marco Basiricò, Chiara Raggi, Paola Bernabei, Tiziana Venesio, Enrico Berrino, Massimo Aglietta, Francesco Leone et al. · 2019 · Cancers
  17. Reduced FOXF1 links unrepaired DNA damage to pulmonary arterial hypertension
    Sarasa Isobe, Ramesh V. Nair, Helen Y. Kang, Lingli Wang, Jan-Renier A. J. Moonen, Tsutomu Shinohara, Aiqin Cao, Shalina Taylor, Shoichiro Otsuki, David P. Marciano et al. · 2023 · Nature Communications
  18. Genome Stability Pathways in Head and Neck Cancers
    Glenn Jenkins, Kenneth John O'Byrne, Benedict James Panizza, Derek J. Richard · 2013 · International Journal of Genomics
  19. Cell cycle inhibitor, p19INK4d, promotes cell survival and decreases chromosomal aberrations after genotoxic insult due to enhanced DNA repair
    María Élida Scassa, Mariela Claudia Marazita, Julieta María Ceruti, Abel L. Carcagno, Pablo F. Sirkin, Marcela González‐Cid, Omar P. Pignataro, Eduardo Tomás Cánepa · 2007 · DNA repair
  20. Systems-level analysis of risk genes reveals the modular nature of schizophrenia
    Jiewei Liu, Ming Li, Xiong‐Jian Luo, Bing Su · 2018 · Schizophrenia Research
  21. Secular Trends in Outcomes for Fanconi Anemia Patients Who Receive Transplants: Implications for Future Studies
    Philip S. Rosenberg, Blanche P. Alter, Gèrard Socié, Éliane Gluckman · 2005 · Transplantation and Cellular Therapy
  22. A cross‐linker‐sensitive myeloid leukemia cell line from a 2‐year‐old boy with severe Fanconi anemia and biallelic FANCD1/BRCA2 mutations
    Stefan Meyer, William D. Fergusson, Anneke B. Oostra, Annette L. Medhurst, Quinten Waisfisz, Johan P. de Winter, Fei Chen, Trevor F. Carr, Jill Clayton‐Smith, Tara Clancy et al. · 2005 · Genes Chromosomes and Cancer
  23. ZNF365 Promotes Stability of Fragile Sites and Telomeres
    Yuqing Zhang, Sandra Jean Shin, Debra Liu, Elena V. Ivanova, Friedrich Foerster, Haoqiang Ying, Hongwu Zheng, Yonghong Xiao, Zhengming Chen, Alexei I. Protopopov et al. · 2013 · Cancer Discovery
  24. Basic and Preclinical Research for Personalized Medicine
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  25. Loss of ribonuclease DIS3 hampers genome integrity in myeloma by disrupting DNA:RNA hybrid metabolism
    Ilaria Gritti, Veronica Basso, Darawan Rinchai, Federica Corigliano, Silvia Pivetti, Marco Gaviraghi, Dalia Rosano, Davide Mazza, Sara Barozzi, Marco Roncador et al. · 2022 · The EMBO Journal
  26. BRCA1: A Missing Link in the Fanconi Anemia/BRCA Pathway
    Alan D. D’Andrea · 2013 · Cancer Discovery
  27. Genetic changes and DNA damage responses in the prostate
    Taija af Hällström, Marikki Laiho · 2008 · The Prostate
  28. Loss of Ubr2, an E3 ubiquitin ligase, leads to chromosome fragility and impaired homologous recombinational repair
    Yan Ouyang, Yong Tae Kwon, Jee Young An, Danny Eller, Shih-Chang Tsai, Silvia V. Diaz-Perez, Joshua J. Troke, Michael A. Teitell, York Marahrens · 2006 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
  29. Multifunctional nanoparticles for targeting cancer and inflammatory diseases
    Shardool Jain, Aatman S. Doshi, Arun K. Iyer, Mansoor M. Amiji · 2013 · Journal of drug targeting
  30. Fanconi Anemia and Ubiquitination
    Yingying Zhang, Xiaowei Zhou, Peitang Huang · 2007 · Journal of genetics and genomics/Journal of Genetics and Genomics
  31. FAVL impairment of the Fanconi anemia pathway promotes the development of human bladder cancer
    Jayabal Panneerselvam, Hwan Ki Park, Jun Zhang, Fred Duafalia Dudimah, Piyan Zhang, Hong Wang, Peiwen Fei · 2012 · Cell Cycle
  32. Ethical considerations in genomic testing for hematologic disorders
    Jonathan Michael Marron, Steven Joffe · 2017 · Blood
  33. Involvement of FANCD2 in Energy Metabolism via ATP5α
    Jayabal Panneerselvam, Chi Ma, Manoj K. Nepal, Yihang Shen, Raymond Che, James Turkson, Peiwen Fei · 2017 · Scientific Reports
  34. The nuclear accumulation of the Fanconi anemia protein FANCE depends on FANCC
    France Léveillé, Miriam Ferrer, Annette L. Medhurst, El Houari Laghmani, Martin A. Rooimans, Patrick Bier, Jûrgen Steltenpool, Tom A. Titus, John H. Postlethwait, Maureen E. Hoatlin et al. · 2006 · DNA repair
  35. Syndromes Predisposing to Pediatric Central Nervous System Tumors: Lessons Learned and New Promises
    Anita Villani, David M. Malkin, Uri Y. Tabori · 2011 · Current Neurology and Neuroscience Reports
  36. Fanconi anemia proteins in telomere maintenance
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  37. Understanding DNA Damage Response and DNA Repair in Multiple Myeloma
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  38. Genomic Instability in Chronic Myeloid Leukemia: Targets for Therapy?
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  39. Selection and the Cell Cycle: Positive Darwinian Selection in a Well-Known DNA Damage Response Pathway
    Mary J. O’Connell · 2010 · Journal of Molecular Evolution
  40. Mammalian SNM1 is required for genome stability
    Aaron Hemphill, Donald A. Bruun, Lori A. Thrun, Yassmine M. N. Akkari, Yumi Torimaru, K. Hejna, Petra M. Jakobs, James Hejna, Steven J.M. Jones, Susan B. Olson et al. · 2008 · Molecular Genetics and Metabolism
  41. 3R coordination by Fanconi anemia proteins
    Gaëtane Macé‐Aimé, Massimo Bogliolo, Jean-Hugues Guervilly, Jean-Antoine Dugas du Villard, Filippo Rosselli · 2005 · Biochimie
  42. MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links
    Qinqin Jiang, Manikandan Paramasivam, Bernadette Aressy, Junmin Wu, Marina A. Bellani, Wei Tong, Michael M. Seidman, Roger A. Greenberg · 2015 · Genes & Development
  43. A score of DNA damage repair pathway with the predictive ability for chemotherapy and immunotherapy is strongly associated with immune signaling pathway in pan-cancer
    Ke Ding, Youhua He, Jinfen Wei, Shuying Fu, Jiajian Wang, Zixi Chen, Haibo Zhang, Yimo Qu, Keying Liang, Xiaocheng Gong et al. · 2022 · Frontiers in Immunology
  44. K63-linked ubiquitination of FANCG is required for its association with the Rap80-BRCA1 complex to modulate homologous recombination repair of DNA interstand crosslinks
    Bin Zhu, Kaowen Yan, Li Li, Menghan Lin, Sufang Zhang, Qiguang He, Duo Zheng, Hua Yang, Genze Shao · 2014 · Oncogene
  45. The involvement of FANCM, FANCI, and checkpoint proteins in the interstrand DNA crosslink repair pathway is conserved in C. elegans
    Kyong Yun Lee, Kee Yang Chung, Hyeon‐Sook Koo · 2010 · DNA repair
  46. Assessment of FANCD2 nuclear foci formation in paraffin-embedded tumors: a potential patient-enrichment strategy for treatment with DNA interstrand crosslinking agents
    Wenrui Duan, Li Gao, Weiqiang Zhao, Marino E. Leon, Wolfgang Sadée, Amy Webb, Kimberly Erin Resnick, Xin Wu, Bhuvaneswari Ramaswamy, David E. Cohn et al. · 2012 · Translational research
  47. Bone marrow transplantation from matched related donors for patients with Fanconi anemia using low‐dose busulfan and cyclophosphamide as conditioning
    Lamia Torjemane, Saloua Ladeb, Tarek Ben Othman, A Abdelkefi, Amel Lakhal, A Ben Abdeladhim · 2005 · Pediatric Blood & Cancer
  48. FANCD2 mRNA Overexpression is a Bona Fide Indicator of Lymph Node Metastasis in Human Colorectal Cancer
    Heita Ozawa, Masaaki Iwatsuki, Koshi Mimori, Tetsuya Sato, Fredrik Johansson, Hiroyuki Toh, Masahiko Watanabe, Masaki Mori · 2010 · Annals of Surgical Oncology
  49. Influence of microglia on retinal progenitor cell turnover and cell replacement
    Andrew D. Dick · 2008 · Eye
  50. Applications of Hemagglutinating Virus of Japan in therapeutic delivery systems
    Yasufumi Kaneda · 2008 · Expert Opinion on Drug Delivery
  51. Bone Marrow Failure: A Child Is Not Just a Small Adult (But an Adult Can Have a Childhood Disease)
    Blanche P. Alter · 2005 · Hematology
  52. Molecular characterization of three novel Fanconi anemia mutations in Israeli Arabs
    Hannah Tamary, Orly Dgany, Helen Toledano, Zvi Shalev, Tatyana Krasnov, Lea Shalmon, Tali Schechter, Dani Bercovich, Dina Attias, Ruth Laor et al. · 2004 · European Journal Of Haematology
  53. Repeated Sequences in CASPASE-5 and FANCD2 but not NF1 Are Targets for Mutation in Microsatellite-Unstable Acute Leukemia/Myelodysplastic Syndrome
    Judith Offman, Karen E. Gascoigne, Fiona Bristow, Peter Macpherson, Margherita Bignami, Ida Casorelli, Giuseppe G.M. Leone, Livio Pagano, Simona Sica, Ozay Halil et al. · 2005 · Molecular Cancer Research
  54. Disparate contributions of the Fanconi anemia pathway and homologous recombination in preventing spontaneous mutagenesis
    John M. Hinz, Peter B. Nham, Salustra S. Urbin, Irene M. Jones, Larry H. Thompson · 2007 · Nucleic Acids Research
  55. DNA Repair: Exploiting the Fanconi Anemia Pathway As a Potential Therapeutic Target
    Tomáš Hucl, Eike Gallmeier · 2011 · Physiological Research
  56. Diagnosis of Fanconi Anaemia by ionising radiation- or mitomycin C-induced micronuclei
    Flavia Zita Francies, Rosalind Wainwright, Janet Poole, Kim De Leeneer, Ilse Coene, Greet Wieme, Hélène Antoine Poirel, Bénédicte Brichard, Stephanie Vermeulen, Anne Vral et al. · 2017 · DNA repair
  57. SARS-CoV-2 and the DNA damage response
    Roger J.A. Grand · 2023 · Journal of General Virology
  58. BRCA /Fanconi anemia pathway implicates chemoresistance to gemcitabine in biliary tract cancer
    Shinsuke Nakashima, Shogo Kobayashi, Hiroaki Nagano, Akira Tomokuni, Yoshito Tomimaru, Tadafumi Asaoka, Naoki Hama, Hiroshi Wada, Koichi Kawamoto, Shigeru Marubashi et al. · 2015 · Cancer Science
  59. A modified thymine for the synthesis of site-specific thymine-guanine DNA interstrand crosslinks
    Jawad Alzeer, Orlando D. Schärer · 2006 · Nucleic Acids Research
  60. Veliparib Alone or in Combination with Mitomycin C in Patients with Solid Tumors With Functional Deficiency in Homologous Recombination Repair
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  61. Regulation of various DNA repair pathways by E3 ubiquitin ligases
    Chandramouli Natarajan, Ken’ichi Takeda · 2017 · Journal of Cancer Research and Therapeutics
  62. Disease classification via gene network integrating modules and pathways
    Zhilong Mi, Binghui Guo, Ziqiao Yin, Jiahui Li, Zhiming Zheng · 2019 · Royal Society Open Science
  63. Loss of GGN Leads to Pre-Implantation Embryonic Lethality and Compromised Male Meiotic DNA Double Strand Break Repair in the Mouse
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  64. Coordinated action of the Fanconi anemia and ataxia telangiectasia pathways in response to oxidative damage
    Pau Castillo Bosch, Massimo Bogliolo, Jordi Surrallés · 2011 · DNA repair
  65. Clinical Significance of FANCD2 Gene Expression and its Association with Tumor Progression in Hepatocellular Carcinoma
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  66. Loss of homologous recombination or non-homologous end-joining leads to radial formation following DNA interstrand crosslink damage
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  67. A role for PKR in hematologic malignancies
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  68. Frequency of Fanconi anemia in Brazil and efficacy of screening for the FANCA 3788-3790del mutation
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  70. The Fanconi Anemia/BRCA Pathway
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  72. The Caenorhabditis elegans FancD2 ortholog is required for survival following DNA damage
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  76. Fanconi anemia D2 protein confers chemoresistance in response to the anticancer agent, irofulven
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  77. Disrupted Signaling through the Fanconi Anemia Pathway Leads to Dysfunctional Hematopoietic Stem Cell Biology: Underlying Mechanisms and Potential Therapeutic Strategies
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  94. Uncoupling of transcription and translation of Fanconi anemia (FANC) complex proteins during spermatogenesis
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  95. Promise and challenges of human iPSC-based hematologic disease modeling and treatment
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  96. Identification of a robust DNA methylation signature for Fanconi anemia.
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