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Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib

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EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy

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Safety and activity of anti-PD-L1 antibody in patients with advanced cancer

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Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial

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Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

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Comprehensive genomic characterization of squamous cell lung cancers

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Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain

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Crizotinib versus Chemotherapy in Advanced ALK -Positive Lung Cancer

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Phase III Study of Afatinib or Cisplatin Plus Pemetrexed in Patients With Metastatic Lung Adenocarcinoma With EGFR Mutations

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Phase III Study Comparing Cisplatin Plus Gemcitabine With Cisplatin Plus Pemetrexed in Chemotherapy-Naive Patients With Advanced-Stage Non–Small-Cell Lung Cancer

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First-Line Crizotinib versus Chemotherapy in ALK -Positive Lung Cancer

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Crizotinib in ROS1-Rearranged Non–Small-Cell Lung Cancer

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Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs

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ROS1 Rearrangements Define a Unique Molecular Class of Lung Cancers

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Ceritinib in ALK -Rearranged Non–Small-Cell Lung Cancer

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Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, double-blind, randomised phase 3 trial

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Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

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Acquired resistance to TKIs in solid tumours: learning from lung cancer

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Lung Cancer That Harbors an HER2 Mutation: Epidemiologic Characteristics and Therapeutic Perspectives

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Phase III trial of maintenance gefitinib or placebo after concurrent chemoradiotherapy and docetaxel consolidation in inoperable stage III non-small-cell lung cancer: SWOG S0023

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Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor–Resistant Disease

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LUX-Lung 4: A Phase II Trial of Afatinib in Patients With Advanced Non–Small-Cell Lung Cancer Who Progressed During Prior Treatment With Erlotinib, Gefitinib, or Both

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A phase 3 trial of whole brain radiation therapy and stereotactic radiosurgery alone versus WBRT and SRS with temozolomide or erlotinib for non-small cell lung cancer and 1 to 3 brain metastases: Radiation Therapy Oncology Group 0320

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Molecular Profiling and Targeted Therapy for Advanced Thoracic Malignancies: A Biomarker-Derived, Multiarm, Multihistology Phase II Basket Trial

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Erlotinib versus radiation therapy for brain metastases in patients with EGFR-mutant lung adenocarcinoma

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Gefitinib/Chemotherapy Vs Chemotherapy in Epidermal Growth Factor Receptor (Egfr) Mutation-Positive Non-Small-Cell Lung Cancer (Nsclc) After Progression on First-Line Gefitinib: the Phase Iii, Randomised Impress Study

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Recent updates on third generation EGFR inhibitors and emergence of fourth generation EGFR inhibitors to combat C797S resistance

Patel, H., Pawara, R., Ansari, A., & Surana, S. (2017) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2017.05.027 · Cited by 170

Immunological off-target effects of imatinib

Zitvogel, L., Rusakiewicz, S., Routy, B., Ayyoub, M., & Kroemer, G. (2016) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2016.41 · Cited by 142

Histone Deacetylase Inhibition Enhances the Antitumor Activity of a MEK Inhibitor in Lung Cancer Cells Harboring RAS Mutations

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